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Volumn 178, Issue 8, 2008, Pages 787-797

Mast cells can mediate vascular permeability through regulation of the PI3K-HIF-1α-VEGF axis

Author keywords

Allergy; Inflammation; Mast cells; Vascular endothelial growth factor; Vascular permeability

Indexed keywords

2 METHOXYESTRADIOL; 2 MORPHOLINO 8 PHENYLCHROMONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OVALBUMIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SU 1498; SU 5614; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN INHIBITOR; WORTMANNIN; BIOLOGICAL MARKER; HIF1A PROTEIN, MOUSE; VASCULOTROPIN A;

EID: 54049109247     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200801-008OC     Document Type: Article
Times cited : (64)

References (47)
  • 2
    • 0026026861 scopus 로고
    • Respiratory membrane permeability and bronchial hyperreactivity in patients with stable asthma: Effects of therapy with inhaled steroids
    • Van de Graaf EA, Out TA, Roos CM, Jansen HM. Respiratory membrane permeability and bronchial hyperreactivity in patients with stable asthma: effects of therapy with inhaled steroids. Am Rev Respir Dis 1991;143:362-368.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 362-368
    • Van de Graaf, E.A.1    Out, T.A.2    Roos, C.M.3    Jansen, H.M.4
  • 3
    • 0036533666 scopus 로고    scopus 로고
    • Contribution of vascular endothelial growth factor to airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma
    • Lee YC, Kwak YG, Song CH. Contribution of vascular endothelial growth factor to airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. J Immunol 2002;168:3595-3600.
    • (2002) J Immunol , vol.168 , pp. 3595-3600
    • Lee, Y.C.1    Kwak, Y.G.2    Song, C.H.3
  • 4
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
    • Dvorak HF, Brown LF, Detmar M, Dvorak AM. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995;146:1029-1039.
    • (1995) Am J Pathol , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3    Dvorak, A.M.4
  • 6
    • 7944239539 scopus 로고    scopus 로고
    • Cysteinyl leukotriene receptor antagonist regulates vascular permeability by reducing vascular endothelial growth factor expression
    • Lee KS, Kim SR, Park HS, Jin GY, Lee YC. Cysteinyl leukotriene receptor antagonist regulates vascular permeability by reducing vascular endothelial growth factor expression. J Allergy Clin Immunol 2004;114:1093-1099.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1093-1099
    • Lee, K.S.1    Kim, S.R.2    Park, H.S.3    Jin, G.Y.4    Lee, Y.C.5
  • 7
    • 0035006275 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in patients with acute asthma
    • Lee YC, Lee HK. Vascular endothelial growth factor in patients with acute asthma. J Allergy Clin Immunol 2001;107:1106.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 1106
    • Lee, Y.C.1    Lee, H.K.2
  • 8
    • 0024533292 scopus 로고
    • Capillary growth in the mesentery of normal young rats: Intravital video and electron microscope analyses
    • Rhodin JA, Fujita H. Capillary growth in the mesentery of normal young rats: intravital video and electron microscope analyses. J Submicrosc Cytol Pathol 1989;21:1-34.
    • (1989) J Submicrosc Cytol Pathol , vol.21 , pp. 1-34
    • Rhodin, J.A.1    Fujita, H.2
  • 9
    • 0025141544 scopus 로고
    • New insights into "the riddle of the mast cells": Microenvironmental regulation of mast cell development and phenotypic heterogeneity
    • Galli SJ. New insights into "the riddle of the mast cells": microenvironmental regulation of mast cell development and phenotypic heterogeneity. Lab Invest 1990;62:5-33.
    • (1990) Lab Invest , vol.62 , pp. 5-33
    • Galli, S.J.1
  • 10
    • 0025017733 scopus 로고
    • Mast cells in the rat heart during normal growth and in cardiac hypertrophy
    • Rakusan K, Sarkar K, Turek Z, Wicker P. Mast cells in the rat heart during normal growth and in cardiac hypertrophy. Circ Res 1990;66:511-516.
    • (1990) Circ Res , vol.66 , pp. 511-516
    • Rakusan, K.1    Sarkar, K.2    Turek, Z.3    Wicker, P.4
  • 11
    • 0030878829 scopus 로고    scopus 로고
    • Complexity and redundancy in the pathogenesis of asthma: Reassessing the roles of mast cells and T cells
    • Galli SJ. Complexity and redundancy in the pathogenesis of asthma: reassessing the roles of mast cells and T cells. J Exp Med 1997;186:343-347.
    • (1997) J Exp Med , vol.186 , pp. 343-347
    • Galli, S.J.1
  • 12
    • 0033604543 scopus 로고    scopus 로고
    • Signaling through the high-affinity IgE receptor FcεRI
    • Turner H, Kinet JP. Signaling through the high-affinity IgE receptor FcεRI. Nature 1999;402:B24-B30.
    • (1999) Nature , vol.402
    • Turner, H.1    Kinet, J.P.2
  • 14
    • 0018096538 scopus 로고
    • v mice and their increase by bone marrow transplantation
    • v mice and their increase by bone marrow transplantation. Blood 1978;52:447-452.
    • (1978) Blood , vol.52 , pp. 447-452
    • Kitamura, Y.1    Go, S.2    Hatanaka, K.3
  • 17
    • 0037382808 scopus 로고    scopus 로고
    • Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma
    • Kwak YG, Song CH, Yi HK, Hwang PH, Kim JS, Lee KS, Lee YC. Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma. J Clin Invest 2003;111:1083-1092.
    • (2003) J Clin Invest , vol.111 , pp. 1083-1092
    • Kwak, Y.G.1    Song, C.H.2    Yi, H.K.3    Hwang, P.H.4    Kim, J.S.5    Lee, K.S.6    Lee, Y.C.7
  • 18
    • 0034618130 scopus 로고    scopus 로고
    • Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice
    • Williams CM, Galli SJ. Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. J Exp Med 2000;192:455-462.
    • (2000) J Exp Med , vol.192 , pp. 455-462
    • Williams, C.M.1    Galli, S.J.2
  • 20
    • 0030810734 scopus 로고    scopus 로고
    • Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice
    • Takeda K, Hamelmann E, Joetham A, Shultz LD, Larson GL, Irvin CG, Gelfand EW. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J Exp Med 1997;186:449-454.
    • (1997) J Exp Med , vol.186 , pp. 449-454
    • Takeda, K.1    Hamelmann, E.2    Joetham, A.3    Shultz, L.D.4    Larson, G.L.5    Irvin, C.G.6    Gelfand, E.W.7
  • 21
    • 0032777466 scopus 로고    scopus 로고
    • Fos localization in cytosolic and nuclear compartments in neurones of the frog, Rana esculenta, brain: An analysis carried out in parallel with GnRH molecular forms
    • Cobellis G, Vallarino M, Meccariello R, Pierantoni R, Masini MA, Mathieu M, Pernas-Alonso R, Chieffi P, Fasano S. Fos localization in cytosolic and nuclear compartments in neurones of the frog, Rana esculenta, brain: an analysis carried out in parallel with GnRH molecular forms. J Neuroendocrinol 1999;11:725-735.
    • (1999) J Neuroendocrinol , vol.11 , pp. 725-735
    • Cobellis, G.1    Vallarino, M.2    Meccariello, R.3    Pierantoni, R.4    Masini, M.A.5    Mathieu, M.6    Pernas-Alonso, R.7    Chieffi, P.8    Fasano, S.9
  • 24
    • 0036795950 scopus 로고    scopus 로고
    • Cockroach extract antigen increases bronchial airway epithelial permeability
    • Antony AB, Tepper RS, Mohammed KA. Cockroach extract antigen increases bronchial airway epithelial permeability. J Allergy Clin Immunol 2002;110:589-595.
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 589-595
    • Antony, A.B.1    Tepper, R.S.2    Mohammed, K.A.3
  • 25
    • 0001929564 scopus 로고
    • Mediators of immediate hypersensitivity
    • Middleton E Jr, Reed CE, Ellis EF, Adkinson NF Jr, Yuninger JW, Busse WW, editors, 4th ed. St. Louis, MO: Mosby;
    • Holgate ST, Robinson C, Church MK. Mediators of immediate hypersensitivity. In: Middleton E Jr, Reed CE, Ellis EF, Adkinson NF Jr, Yuninger JW, Busse WW, editors. Allergy: principles and practice, 4th ed. St. Louis, MO: Mosby; 1993. pp. 267-301.
    • (1993) Allergy: Principles and practice , pp. 267-301
    • Holgate, S.T.1    Robinson, C.2    Church, M.K.3
  • 26
    • 0028821698 scopus 로고
    • Mast-cell-leukocyte cytokine cascades in allergic inflammation
    • Galli SJ, Costa JJ. Mast-cell-leukocyte cytokine cascades in allergic inflammation. Allergy 1995;50:851-862.
    • (1995) Allergy , vol.50 , pp. 851-862
    • Galli, S.J.1    Costa, J.J.2
  • 27
    • 0032555946 scopus 로고    scopus 로고
    • Mast cells can secrete vascular permeability factor/ vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of Fcε receptor I expression
    • Boesiger J, Tsai M, Maurer M, Yamaguchi M, Brown LF, Claffey KP, Dvorak HF, Galli SJ. Mast cells can secrete vascular permeability factor/ vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of Fcε receptor I expression. J Exp Med 1998;188:1135-1145.
    • (1998) J Exp Med , vol.188 , pp. 1135-1145
    • Boesiger, J.1    Tsai, M.2    Maurer, M.3    Yamaguchi, M.4    Brown, L.F.5    Claffey, K.P.6    Dvorak, H.F.7    Galli, S.J.8
  • 28
    • 0031182836 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor by human eosinophils: Upregulation by granulocyte macrophage colony-stimulating factor and interleukin-5
    • Horiuchi T, Weller PF. Expression of vascular endothelial growth factor by human eosinophils: upregulation by granulocyte macrophage colony-stimulating factor and interleukin-5. Am J Respir Cell Mol Biol 1997;17:70-77.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 70-77
    • Horiuchi, T.1    Weller, P.F.2
  • 29
    • 0034995813 scopus 로고    scopus 로고
    • Gene expression of vascular endothelial growth factor and its receptors and angiogenesis in bronchial asthma
    • Hoshino M, Nakamura Y, Hamid QA. Gene expression of vascular endothelial growth factor and its receptors and angiogenesis in bronchial asthma. J Allergy Clin Immunol 2001;107:1034-1038.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 1034-1038
    • Hoshino, M.1    Nakamura, Y.2    Hamid, Q.A.3
  • 30
    • 0028229422 scopus 로고
    • Piecemeal degranulation of mast cells in the inflammatory eyelid lesions of interleukin-4 transgenic mice: Evidence of mast cell histamine release in vivo by diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry
    • Dvorak AM, Tepper RI, Weller PF, Morgan ES, Estrella P, Monahan-Earley RA, Galli SJ. Piecemeal degranulation of mast cells in the inflammatory eyelid lesions of interleukin-4 transgenic mice: evidence of mast cell histamine release in vivo by diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry. Blood 1994;83:3600-3612.
    • (1994) Blood , vol.83 , pp. 3600-3612
    • Dvorak, A.M.1    Tepper, R.I.2    Weller, P.F.3    Morgan, E.S.4    Estrella, P.5    Monahan-Earley, R.A.6    Galli, S.J.7
  • 31
    • 0033522927 scopus 로고    scopus 로고
    • Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
    • Fujio Y, Walsh K. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J Biol Chem 1999;274:16349-16354.
    • (1999) J Biol Chem , vol.274 , pp. 16349-16354
    • Fujio, Y.1    Walsh, K.2
  • 32
    • 0033538057 scopus 로고    scopus 로고
    • The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling
    • Thakker GD, Hajjar DP, Muller WA, Rosengart TK. The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling. J Biol Chem 1999;274:10002-10007.
    • (1999) J Biol Chem , vol.274 , pp. 10002-10007
    • Thakker, G.D.1    Hajjar, D.P.2    Muller, W.A.3    Rosengart, T.K.4
  • 33
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol 2001;21:3995-4004.
    • (2001) Mol Cell Biol , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 34
    • 0037008770 scopus 로고    scopus 로고
    • Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
    • Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, Van Obberghen E. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. J Biol Chem 2002;277:27975-27981.
    • (2002) J Biol Chem , vol.277 , pp. 27975-27981
    • Treins, C.1    Giorgetti-Peraldi, S.2    Murdaca, J.3    Semenza, G.L.4    Van Obberghen, E.5
  • 35
    • 0043234256 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells
    • Mottet D, Dumont V, Deccache Y, Demazy C, Ninane N, Raes M, Michiels C. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells. J Biol Chem 2003;278:31277-31285.
    • (2003) J Biol Chem , vol.278 , pp. 31277-31285
    • Mottet, D.1    Dumont, V.2    Deccache, Y.3    Demazy, C.4    Ninane, N.5    Raes, M.6    Michiels, C.7
  • 36
    • 17144372970 scopus 로고    scopus 로고
    • A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells
    • Li YM, Zhou BP, Deng J, Pan Y, Hay N, Hung MC. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells. Cancer Res 2005;65:3257-3263.
    • (2005) Cancer Res , vol.65 , pp. 3257-3263
    • Li, Y.M.1    Zhou, B.P.2    Deng, J.3    Pan, Y.4    Hay, N.5    Hung, M.C.6
  • 37
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • 2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 1999;15:551-578.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 38
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang GL, Semenza GL. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 1995;270:1230-1237.
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 39
    • 0035966119 scopus 로고    scopus 로고
    • Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes
    • Lukashev D, Caldwell C, Ohta A, Chen P, Sitkovsky M. Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes. J Biol Chem 2001;276:48754-48763.
    • (2001) J Biol Chem , vol.276 , pp. 48754-48763
    • Lukashev, D.1    Caldwell, C.2    Ohta, A.3    Chen, P.4    Sitkovsky, M.5
  • 40
    • 0347334750 scopus 로고    scopus 로고
    • IL-1beta-mediated upregulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
    • Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L. IL-1beta-mediated upregulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J 2003;17:2115-2117.
    • (2003) FASEB J , vol.17 , pp. 2115-2117
    • Jung, Y.J.1    Isaacs, J.S.2    Lee, S.3    Trepel, J.4    Neckers, L.5
  • 41
    • 33745451812 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1alpha in allergic airway disease of mice
    • Lee KS, Kim SR, Park SJ, Park HS, Min KH, Jin SM, Lee MK, Kim UH, Lee YC. Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1alpha in allergic airway disease of mice. J Allergy Clin Immunol 2006;118:120-127.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 120-127
    • Lee, K.S.1    Kim, S.R.2    Park, S.J.3    Park, H.S.4    Min, K.H.5    Jin, S.M.6    Lee, M.K.7    Kim, U.H.8    Lee, Y.C.9
  • 43
  • 44
    • 0035049357 scopus 로고    scopus 로고
    • An autocrine loop mediates expression of vascular endothelial growth factor in human dermal microvascular endothelial cells
    • Vega-Diaz B, Herron GS, Michel S. An autocrine loop mediates expression of vascular endothelial growth factor in human dermal microvascular endothelial cells. J Invest Dermatol 2001;116:525-530.
    • (2001) J Invest Dermatol , vol.116 , pp. 525-530
    • Vega-Diaz, B.1    Herron, G.S.2    Michel, S.3
  • 45
    • 0037441745 scopus 로고    scopus 로고
    • The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3
    • Spiekermann K, Dirschinger RJ, Schwab R, Bagrintseva K, Faber F, Buske C, Schnittger S, Kelly LM, Gilliland G, Hiddemann W. The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3. Blood 2003;101:1494-1504.
    • (2003) Blood , vol.101 , pp. 1494-1504
    • Spiekermann, K.1    Dirschinger, R.J.2    Schwab, R.3    Bagrintseva, K.4    Faber, F.5    Buske, C.6    Schnittger, S.7    Kelly, L.M.8    Gilliland, G.9    Hiddemann, W.10
  • 47
    • 0036325621 scopus 로고    scopus 로고
    • Spiekermann K, Faber F, Voswinckel R, Hiddemann W. The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells. Exp Hematol 2002;30:767-773. Am J Respir Crit Care Med 178. pp 798-804, 2008
    • Spiekermann K, Faber F, Voswinckel R, Hiddemann W. The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells. Exp Hematol 2002;30:767-773. Am J Respir Crit Care Med Vol 178. pp 798-804, 2008


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