Hypoxic stress up-regulates the expression of Toll-like receptor 4 in macrophages via hypoxia-inducible factor

Immunology

Volumn 129, Issue 4, 2010, Pages 516-524

  Kim, So Young ^a   Choi, Yong Jun ^a   Joung, Sun Myung ^a   Lee, Byung Ho ^b   Jung, Yi Sook ^c   Lee, Joo Young ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

^c Ajou University   (South Korea)

Author keywords

Inflammation; Innate immunity; Macrophages monocytes; Toll receptors Toll like receptors; Transcription factors gene regulation

Indexed keywords

COBALT CHLORIDE; CYCLOOXYGENASE 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HYPOXIA INDUCIBLE FACTOR; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ARTICLE; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; HYPOXIA; INFLAMMATION; LYMPHOCYTE ACTIVATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; UPREGULATION;

ANIMALS; ANOXIA; CELL HYPOXIA; CELLS, CULTURED; COBALT; GENE EXPRESSION PROFILING; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 77949383238     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03203.x     Document Type: Article

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