Latent factor analysis to discover pathway-associated putative segmental aneuploidies in human cancers

PLoS Computational Biology

Volumn 6, Issue 9, 2010, Pages

  Lucas, Joseph E ^a   Kung, Hsiu Ni ^a,b   Chi, Jen Tsan A ^a,b  

^a DUKE UNIVERSITY   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CLONING; DIAGNOSIS; DISEASES; FACTOR ANALYSIS; GENE EXPRESSION; MULTIVARIANT ANALYSIS;

ANEUPLOIDY; BREAST CANCER; CELL LINES; COPY-NUMBER ALTERATIONS; GENE SIGNATURES; GENES EXPRESSION; HUMAN CANCER; LATENT FACTOR; LATENT FACTOR ANALYSIS; TUMOR PROGRESSIONS;

TUMORS;

FACTOR 26 PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG; MESSENGER RNA;

ANEUPLOIDY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 12Q; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA MICROARRAY; FACTORIAL ANALYSIS; GENE DOSAGE; GENE DUPLICATION; GENE EXPRESSION; GENE FUNCTION; GENETIC LINKAGE; GENETIC SIGNATURE; HUMAN; HUMAN CELL; HYPOXIA; LACTIC ACIDOSIS; LATENT FACTOR ANALYSIS; MOLECULAR CLONING; PROGNOSIS; PROMOTER REGION; TUMOR MICROENVIRONMENT; ANTIBODY SPECIFICITY; BIOLOGY; BREAST TUMOR; CELL HYPOXIA; CLUSTER ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC DATABASE; GENETICS; METABOLISM; METHODOLOGY; SIGNAL TRANSDUCTION; STATISTICAL MODEL; TUMOR CELL LINE;

ACIDOSIS, LACTIC; ANEUPLOIDY; BREAST NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; CLUSTER ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; DNA COPY NUMBER VARIATIONS; FEMALE; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, STATISTICAL; ORGAN SPECIFICITY; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 78049422909     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000920     Document Type: Article

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