메뉴 건너뛰기




Volumn 8, Issue 5, 2005, Pages 381-392

Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAS PROTEIN;

EID: 27644556527     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2005.10.014     Document Type: Article
Times cited : (158)

References (40)
  • 1
    • 0023177629 scopus 로고
    • Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region
    • M.A. Bender, T.D. Palmer, R.E. Gelinas, and A.D. Miller Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region J. Virol. 61 1987 1639 1646
    • (1987) J. Virol. , vol.61 , pp. 1639-1646
    • Bender, M.A.1    Palmer, T.D.2    Gelinas, R.E.3    Miller, A.D.4
  • 2
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • G. Bergers, and L.E. Benjamin Tumorigenesis and the angiogenic switch Nat. Rev. Cancer 3 2003 401 410
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 3
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • J.L. Bos ras oncogenes in human cancer: a review Cancer Res. 49 1989 4682 4689
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 4
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • T.R. Brummelkamp, R. Bernards, and R. Agami Stable suppression of tumorigenicity by virus-mediated RNA interference Cancer Cell 2 2002 243 247
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 5
    • 0842281652 scopus 로고    scopus 로고
    • Rho and Rac take center stage
    • K. Burridge, and K. Wennerberg Rho and Rac take center stage Cell 116 2004 167 179
    • (2004) Cell , vol.116 , pp. 167-179
    • Burridge, K.1    Wennerberg, K.2
  • 7
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • L.M. Coussens, and Z. Werb Inflammation and cancer Nature 420 2002 860 867
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 8
    • 85047698904 scopus 로고    scopus 로고
    • Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation
    • M. Dajee, M. Tarutani, H. Deng, T. Cai, and P.A. Khavari Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation Oncogene 21 2002 1527 1538
    • (2002) Oncogene , vol.21 , pp. 1527-1538
    • Dajee, M.1    Tarutani, M.2    Deng, H.3    Cai, T.4    Khavari, P.A.5
  • 9
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • H.F. Dvorak Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing N. Engl. J. Med. 315 1986 1650 1659
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 10
    • 0041846652 scopus 로고    scopus 로고
    • Ral-GTPases: Approaching their 15 minutes of fame
    • L.A. Feig Ral-GTPases: approaching their 15 minutes of fame Trends Cell Biol. 13 2003 419 425
    • (2003) Trends Cell Biol. , vol.13 , pp. 419-425
    • Feig, L.A.1
  • 11
    • 0742287062 scopus 로고    scopus 로고
    • Conditional animal models: A strategy to define when oncogenes will be effective targets to treat cancer
    • S. Giuriato, K. Rabin, A.C. Fan, C.M. Shachaf, and D.W. Felsher Conditional animal models: a strategy to define when oncogenes will be effective targets to treat cancer Semin. Cancer Biol. 14 2004 3 11
    • (2004) Semin. Cancer Biol. , vol.14 , pp. 3-11
    • Giuriato, S.1    Rabin, K.2    Fan, A.C.3    Shachaf, C.M.4    Felsher, D.W.5
  • 14
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • A.L. Harris Hypoxia - a key regulatory factor in tumour growth Nat. Rev. Cancer 2 2002 38 47
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 15
    • 20344365798 scopus 로고    scopus 로고
    • BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms
    • N. Ikehara, S. Semba, M. Sakashita, N. Aoyama, M. Kasuga, and H. Yokozaki BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms Int. J. Cancer 115 2005 943 950
    • (2005) Int. J. Cancer , vol.115 , pp. 943-950
    • Ikehara, N.1    Semba, S.2    Sakashita, M.3    Aoyama, N.4    Kasuga, M.5    Yokozaki, H.6
  • 16
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
    • G. Kulik, A. Klippel, and M.J. Weber Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt Mol. Cell. Biol. 17 1997 1595 1606
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 17
    • 4344617184 scopus 로고    scopus 로고
    • Leveling the playing field
    • K.H. Lim, and C.M. Counter Leveling the playing field Mol. Cell 15 2004 491 492
    • (2004) Mol. Cell , vol.15 , pp. 491-492
    • Lim, K.H.1    Counter, C.M.2
  • 19
    • 0142227019 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
    • J. Luo, B.D. Manning, and L.C. Cantley Targeting the PI3K-Akt pathway in human cancer: Rationale and promise Cancer Cell 4 2003 257 262
    • (2003) Cancer Cell , vol.4 , pp. 257-262
    • Luo, J.1    Manning, B.D.2    Cantley, L.C.3
  • 21
    • 0038011176 scopus 로고    scopus 로고
    • Rat mammary carcinogenesis induced by in situ expression of constitutive Raf kinase activity is prevented by tethering Raf to the plasma membrane
    • D.R. McFarlin, and M.N. Gould Rat mammary carcinogenesis induced by in situ expression of constitutive Raf kinase activity is prevented by tethering Raf to the plasma membrane Carcinogenesis 24 2003 1149 1153
    • (2003) Carcinogenesis , vol.24 , pp. 1149-1153
    • McFarlin, D.R.1    Gould, M.N.2
  • 22
    • 0037273083 scopus 로고    scopus 로고
    • Affinity with Raf is sufficient for Ras to efficiently induce rat mammary carcinomas
    • D.R. McFarlin, M.J. Lindstrom, and M.N. Gould Affinity with Raf is sufficient for Ras to efficiently induce rat mammary carcinomas Carcinogenesis 24 2003 99 105
    • (2003) Carcinogenesis , vol.24 , pp. 99-105
    • McFarlin, D.R.1    Lindstrom, M.J.2    Gould, M.N.3
  • 24
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes - Bipolar effects of the tumour stroma in cancer
    • M.M. Mueller, and N.E. Fusenig Friends or foes - bipolar effects of the tumour stroma in cancer Nat. Rev. Cancer 4 2004 839 849
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 25
    • 27644525734 scopus 로고    scopus 로고
    • A genetically defined normal human somatic cell system to study ras oncogenesis in vitro and in vivo
    • W.E. Balch, C.J. Der, A. Hall, eds. (San Diego, CA: Academic Press), in press.
    • O'Hayer, K.M., and Counter, C.M. (2005). A genetically defined normal human somatic cell system to study ras oncogenesis in vitro and in vivo. In Methods in Enzymology, Volume 407, Regulators and Effectors of Small GTPases, Part H: Ras Family, W.E. Balch, C.J. Der, A. Hall, eds. (San Diego, CA: Academic Press), in press.
    • (2005) Methods in Enzymology, Volume 407, Regulators and Effectors of Small GTPases, Part H: Ras Family , vol.407
    • O'Hayer, K.M.1    Counter, C.M.2
  • 26
    • 0037013147 scopus 로고    scopus 로고
    • Suppression of Myc-induced apoptosis in β cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression
    • S. Pelengaris, M. Khan, and G.I. Evan Suppression of Myc-induced apoptosis in β cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression Cell 109 2002 321 334
    • (2002) Cell , vol.109 , pp. 321-334
    • Pelengaris, S.1    Khan, M.2    Evan, G.I.3
  • 27
    • 1342288971 scopus 로고    scopus 로고
    • Opinion: Comparative biology of mouse versus human cells: Modelling human cancer in mice
    • A. Rangarajan, and R.A. Weinberg Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice Nat. Rev. Cancer 3 2003 952 959
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 952-959
    • Rangarajan, A.1    Weinberg, R.A.2
  • 28
    • 4344646902 scopus 로고    scopus 로고
    • Species- and cell type-specific requirements for cellular transformation
    • A. Rangarajan, S.J. Hong, A. Gifford, and R.A. Weinberg Species- and cell type-specific requirements for cellular transformation Cancer Cell 6 2004 171 183
    • (2004) Cancer Cell , vol.6 , pp. 171-183
    • Rangarajan, A.1    Hong, S.J.2    Gifford, A.3    Weinberg, R.A.4
  • 31
    • 11244313840 scopus 로고    scopus 로고
    • Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation
    • A. Singh, A.E. Karnoub, T.R. Palmby, E. Lengyel, J. Sondek, and C.J. Der Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation Oncogene 23 2004 9369 9380
    • (2004) Oncogene , vol.23 , pp. 9369-9380
    • Singh, A.1    Karnoub, A.E.2    Palmby, T.R.3    Lengyel, E.4    Sondek, J.5    Der, C.J.6
  • 32
    • 0024545162 scopus 로고
    • Definition of the human raf amino-terminal regulatory region by deletion mutagenesis
    • V.P. Stanton, D.W. Nichols, A.P. Laudano, and G.M. Cooper Definition of the human raf amino-terminal regulatory region by deletion mutagenesis Mol. Cell. Biol. 9 1989 639 647
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 639-647
    • Stanton, V.P.1    Nichols, D.W.2    Laudano, A.P.3    Cooper, G.M.4
  • 33
    • 0037439686 scopus 로고    scopus 로고
    • Inducible activation of Ras and Raf in adult epidermis
    • M. Tarutani, T. Cai, M. Dajee, and P.A. Khavari Inducible activation of Ras and Raf in adult epidermis Cancer Res. 63 2003 319 323
    • (2003) Cancer Res. , vol.63 , pp. 319-323
    • Tarutani, M.1    Cai, T.2    Dajee, M.3    Khavari, P.A.4
  • 34
    • 0038335337 scopus 로고    scopus 로고
    • Ras signaling, deregulation of gene expression and oncogenesis
    • A.S. Ulku, and C.J. Der Ras signaling, deregulation of gene expression and oncogenesis Cancer Treat. Res. 115 2003 189 208
    • (2003) Cancer Treat. Res. , vol.115 , pp. 189-208
    • Ulku, A.S.1    Der, C.J.2
  • 35
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase AKT pathway in human cancer
    • I. Vivanco, and C.L. Sawyers The phosphatidylinositol 3-kinase AKT pathway in human cancer Nat. Rev. Cancer 2 2002 489 501
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 37
    • 0029950722 scopus 로고    scopus 로고
    • A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation
    • M.A. White, T. Vale, J.H. Camonis, E. Schaefer, and M.H. Wigler A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation J. Biol. Chem. 271 1996 16439 16442
    • (1996) J. Biol. Chem. , vol.271 , pp. 16439-16442
    • White, M.A.1    Vale, T.2    Camonis, J.H.3    Schaefer, E.4    Wigler, M.H.5
  • 38
    • 0030728532 scopus 로고    scopus 로고
    • Stimulation of gene induction and cell growth by the Ras effector Rlf
    • R.M. Wolthuis, N.D. de Ruiter, R.H. Cool, and J.L. Bos Stimulation of gene induction and cell growth by the Ras effector Rlf EMBO J. 16 1997 6748 6761
    • (1997) EMBO J. , vol.16 , pp. 6748-6761
    • Wolthuis, R.M.1    De Ruiter, N.D.2    Cool, R.H.3    Bos, J.L.4
  • 40
    • 0032508517 scopus 로고    scopus 로고
    • Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase
    • J. Yan, S. Roy, A. Apolloni, A. Lane, and J.F. Hancock Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase J. Biol. Chem. 273 1998 24052 24056
    • (1998) J. Biol. Chem. , vol.273 , pp. 24052-24056
    • Yan, J.1    Roy, S.2    Apolloni, A.3    Lane, A.4    Hancock, J.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.