A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer

Cell

Volumn 114, Issue 3, 2003, Pages 323-334

  Lamb, Justin ^a,b   Ramaswamy, Sridhar ^a,b   Ford, Heide L ^a,e   Contreras, Bernardo ^a   Martinez, Robert V ^a,e   Kittrell, Frances S ^c   Zahnow, Cynthia A ^d   Patterson, Nick ^b   Golub, Todd R ^a,b   Ewen, Mark E ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIN D1;

ARTICLE; CANCER; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC ANALYSIS; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; UNINDEXED SEQUENCE;

EID: 0042354669     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00570-1     Document Type: Article

References (48)

1. Alizadeh A.A., Eisen M.B., Davis R.E., Ma C., Lossos I.S., Rosenwald A., Boldrick J.C., Sabet H., Tran T., Yu X.et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 403:2000;503-511.
2. Bhattacharjee A., Richards W.G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M.et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc. Natl. Acad. Sci. USA. 98:2001;13790-13795.
3. Bienvenu F., Gascan H., Coqueret O. Cyclin D1 represses STAT3 activation through a cdk4-independent mechanism. J. Biol. Chem. 276:2001;16840-16847.
4. DeRisi J.L., Iyer V.R., Brown P.O. Exploring the metabolic and genetic control of gene expression on a genomic scale. Science. 278:1997;680-686.
5. Descombes P., Schibler U. A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell. 67:1991;569-579.
6. Desprez P.-Y., Roskelley C., Campisi J., Bissell M.J. Isolation of functional cell lines from a mouse mammary epithelial cell strain. the importance of basement membrane and cell-cell interaction Mol. Cell. Diff. 1:1993;99-110.
7. Dyson N. The regulation of E2F by pRb-family proteins. Genes Dev. 12:1998;2245-2262.
8. Gaugitsch H.W., Prieschl E.E., Kalthoff F., Huber N.E., Baumruker T. A novel transiently expressed, integral membrane protein linked to cell activation. Molecular cloning via the rapid degradation signal AUUUA. J. Biol. Chem. 267:1992;11267-11273.
9. Golub T.R., Slonim D.K., Tamayo P., Huard C., Gaasenbeek M., Mesirov J.P., Coller H., Loh M.L., Downing J.R., Calgiuri M.A.et al. Molecular classification of cancer. Class discovery and class prediction by gene expression monitoring Science. 286:1999;531-537.
10. Hall M., Peters G. Genetic alterations of cyclins, cyclin-dependent kinases, and cdk inhibitors in human cancer. Adv. Cancer Res. 68:1996;67-108.
11. He T.-C., Zhou S., da Costa L.T., Yu J., Kinzler K.W., Vogelstein B. A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. USA. 95:1998;2509-2514.
12. Hinds P.W., Dowdy S.F., Eaton E.N., Arnold A., Weinberg R.A. Function of a human cyclin gene as an oncogene. Proc. Natl. Acad. Sci. USA. 91:1994;709-713.
13. Hollander M., Wolfe D. Nonparametric Statistical Methods, second edition. 1999;Wiley, New York.
14. Hughes T.R., Marton M.J., Jones A.R., Roberts C.J., Stoughton R., Armour C.D., Bennett H.A., Coffey E., Dai H., He Y.D.et al. Functional discovery via a compendium of expression profiles. Cell. 102:2000;109-126.
15. Inoue K., Sherr C.J. Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent kinase-independent mechanism. Mol. Cell. Biol. 18:1998;1590-1600.
16. Ishida S., Huang E., Zuzan H., Spang R., Leone G., West M., Nevins J.R. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol. Cell. Biol. 21:2001;4684-4699.
17. Kamano H., Klempnauer K.-H. B-Myb and cyclin D1 mediate heat shock element dependent activation of the human HSP70 promoter. Oncogene. 14:1997;1223-1229.
18. Kittrell F.S., Oborn C.J., Medina D. Development of mammary preneoplasias in vivo from mouse mammary epithelial cell lines in vitro. Cancer Res. 52:1992;1924-1932.
19. Knudsen K.E., Cavenee W.K., Arden K.C. D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability. Cancer Res. 59:1999;2297-2301.
20. Lamb J., Ladha M.H., McMahon C., Sutherland R.L., Ewen M.E. Regulation of the functional interaction between cyclin D1 and the estrogen receptor. Mol. Cell. Biol. 20:2000;8667-8675.
21. Lekstrom-Himes J., Xanthopoulos K.G. Biological role of the CCAAT/enhancer-binding protein family of transcription factors. J. Biol. Chem. 273:1998;28545-28548.
22. Neuman E., Ladha M.H., Lin N., Upton T.M., Miller S.J., DiRenzo J., Pestell R.G., Hinds P.W., Dowdy S.F., Brown M., Ewen M.E. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Mol. Cell. Biol. 17:1997;5338-5347.
23. Oyama T., Kashiwabara K., Yoshimoto K., Arnold A., Koerner F. Frequent overexpression of the cyclin D1 oncogene in invasive lobular carcinoma of the breast. Cancer Res. 58:1998;2876-2880.
24. Perou C.M., Sorlie T., Eisen M.B., van de Rijn M., Jeffrey S.S., Rees C.A., Pollack J.R., Ross D.T., Johnsen H., Akslen L.A.et al. Molecular portraits of human breast tumours. Nature. 406:2000;747-752.
25. Pomeroy S.L., Tamayo P., Gaasenbeek M., Sturla L.M., Angelo M., McLaughlin M.E., Kim J.Y., Goumnerova L.C., Black P.M., Lau C.et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature. 415:2002;436-442.
26. Ramaswamy S., Tamayo P., Rifkin R., Mukherjee S.C.-H., Yeang C.-H., Angelo M., Ladd C., Reich M., Latulippe E., Mesirov J.P.et al. Multiclass cancer diagnosis using tumor gene expression signatures. Proc. Natl. Acad. Sci. USA. 98:2001;15149-15154.
27. Ratineau C., Petry M.W., Mutoh H., Leiter A.B. Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD. J. Biol. Chem. 277:2002;8847-8853.
28. Raught B., Liao W.S., Rosen J.M. Developmentally and hormonally regulated CCAAT/enhancer-binding protein isoforms influence beta-casein gene expression. Mol. Endocrinol. 9:1995;1223-1232.
29. Raught B., Gingras A.C., James A., Medina D., Sonenberg N., Rosen J.M. Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2 alpha are correlated with neoplastic transformation of mammary epithelial cells. Cancer Res. 56:1996;4382-4386.
30. Rosenberg C.L., Wong E., Petty E.M., Bale A.E., Tsujimoto Y., Harris N.L., Arnold A. PRAD1, a candidate BCL1 oncogene. mapping and expression in centrocytic lymphoma Proc. Natl. Acad. Sci. USA. 88:1991;9638-9642.
31. Screpanti I., Romani L., Musiani P., Modesti A., Fattori E., Lazzaro D., Sellitto C., Scarpa S., Bellavia D., Lattanzio G. Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice. EMBO J. 14:1995;1932-1941.
32. Sherr C.J. G1 phase progression. Cycling on cue Cell. 79:1994;551-555.
33. Sherr C.J., Roberts J.M. CDK inhibitors. positive and negative regulators of G1-phase progression Genes Dev. 15:1999;1501-1512.
34. Singh D., Febbo P.G., Ross K., Jackson D.G., Manola J., Ladd C., Tamayo P., Renshaw A.A., D'Amico A.V., Richie J.P.et al. Gene expression correlates of clinical prostate cancer behavior. Cancer Cell. 1:2002;203-209.
35. Siu F., Chen C., Zhong C., Kilberg M.S. CCAAT/enhancer-binding protein-beta is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene. J. Biol. Chem. 276:2001;48100-48107.
36. Staunton J.E., Slonim D.K., Coller H.A., Tamayo P., Angelo M.J., Park J., Scherf U., Lee J.K., Reinhold W.O., Weinstein J.N.et al. Chemosensitivity prediction by transcriptional profiling. Proc. Natl. Acad. Sci. USA. 98:2001;10787-10792.
37. Su A.I., Welsh J.B., Sapinoso L.M., Kern S.G., Dimitrov P., Lapp H., Schultz P.G., Powell S.M., Moskaluk C.A., Frierson H.F., Hampton G.M. Molecular classification of human carcinomas by use of gene expression signatures. Cancer Res. 61:2001;7388-7393.
38. Tsukada J., Saito K., Waterman W.R., Webb A.C., Auron P.E. Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene. Mol. Cell. Biol. 14:1994;7285-7297.
39. Ubeda M., Schmitt-Ney M., Ferrer J., Habener J.F. CHOP/GADD153 and methionyl-tRNA synthetase (MetRS) genes overlap in a conserved region that controls mRNA stability. Biochem. Biophys. Res. Commun. 262:1999;31-38.
40. van 't Veer L.J., Dai H., van de Vijver M.J., He Y.D., Hart A.A., Mao M., Peterse H.L., van der Kooy K., Marton M.J., Witteveen A.T.et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 415:2002;530-536.
41. Vos C.B., Ter Haar N.T., Peterse J.L., Cornelisse C.J., van de Vijver M.J. Cyclin D1 gene amplification and overexpression are present in ductal carcinoma in situ of the breast. J. Pathol. 187:1999;279-284.
42. Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell. 81:1995;323-330.
43. Weinstat-Saslow D., Merino M.J., Manrow R.E., Lawrence J.A., Bluth R.F., Wittenbel K.D., Simpson J.F., Page D.L., Steeg P.S. Overexpression of cyclin D1 mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions. Nat. Med. 1:1995;1257-1260.
44. Zahnow C.A., Younes P., Laucirica R., Rosen J.M. Overexpression of C/EBPbeta-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer. J. Natl. Cancer Inst. 89:1997;1887-1891.
45. Zahnow C.A., Cardiff R.D., Laucirica R., Medina D., Rosen J.M. A role for CCAAT/enhancer binding protein beta-liver-enriched inhibitory protein in mammary epithelial cell proliferation. Cancer Res. 61:2001;261-269.
46. Zukerberg L.R., Yang W.-I., Gadd M., Thor A.D., Koerner F.C., Schmidt E.V., Arnold A. Cyclin D1 (PRAD1) protein expression in breast cancer. approximately one-third of infiltrating mammary carcinomas show overexpression of the cyclin D1 oncogene Mod. Pathol. 8:1995;560-567.
47. Zukerberg L.R., Benedict W.F., Arnold A., Dyson N., Harlow E., Harris N.L. Expression of the retinoblastoma protein in low-grade B-cell lymphoma. relationship to cyclin D1 Blood. 88:1996;268-276.
48. Zwijsen R.M.L., Wientjens E., Klompmaker R., van der Sman J., Bernards R., Michalides R.J.A.M. CDK-independent activation of estrogen receptor by cyclin D1. Cell. 88:1997;405-415.