Binding of endostatin to phosphatidylserine-containing membranes and formation of amyloid-like fibers

Biochemistry

Volumn 44, Issue 8, 2005, Pages 2857-2863

  Zhao, Hongxia ^a   Jutila, Arimatti ^a   Nurminen, Tuula ^a   Wickström, Sara A ^b   Keski Oja, Jorma ^b   Kinnunen, Paavo K J ^a,c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c MEMPHYS   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOSTATIN; PHOSPHATIDYLGLYCEROL (PG); TUMOR ANGIOGENESIS; TUMOR GROWTH;

BIOCHEMISTRY; FLUORESCENCE; GLYCEROL; NATURAL FIBERS; PHOSPHOLIPIDS; RESONANCE; TUMORS;

COLLAGEN;

AMYLOID; CONGO RED; ENDOSTATIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLGLYCEROL; PHOSPHATIDYLSERINE; TRYPTOPHAN;

ARTICLE; BIREFRINGENCE; CELL MEMBRANE PERMEABILITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HYDROPHOBICITY; MEMBRANE BINDING; PHASE CONTRAST MICROSCOPY; POLARIZATION MICROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SYNTHESIS;

AMYLOID; ANGIOGENESIS INHIBITORS; ANTINEOPLASTIC AGENTS; ENDOSTATINS; KINETICS; LIPOSOMES; MEMBRANES, ARTIFICIAL; MICROSCOPY, PHASE-CONTRAST; PHOSPHATIDYLSERINES; PROTEIN BINDING; SPECTROMETRY, FLUORESCENCE;

BIOCHEMISTRY; COLLAGEN; FLUORESCENCE; GLYCEROL; LIPIDS; NATURAL FIBERS; RESONANCE; TUMORS;

EID: 14344250143     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048510j     Document Type: Article

References (38)

1. Dixelius, J., Cross, M. J., Matsumoto, T., and Claesson-Welsh, L. (2003) Endostatin action and intracellular signaling: β-Catenin as a potential target? Cancer Lett. 196, 1-12.
2. Sim, B. K., MacDonald, N. J., and Gubish, E. R. (2000) Angiogenesis and endostatin: Endogenous inhibitors of tumor growth, Cancer Metastasis Rev. 19, 181-190.
3. Boehm, T., Folkman, J., Browder, T., and O'Reilly, M. S. (1997) Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance, Nature 390, 404-407.
4. O'Reilly, M. S., Boehm, T., Shing, Y., Fukai, N., Vasios, G., Lane, W. S., Flynn, E., Birkhead, J. R., Olsen, B. R., and Folkman, J. (1997) Endostatin: An endogenous inhibitor of angiogenesis and tumor growth, Cell 88, 277-285.
5. Kim, Y. M., Hwang, S., Kim, Y. M., Pyun, B. J., Kim, T. Y., Lee, S. T., Gho, Y. S., and Kwon, Y. G. (2002) Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1, J. Biol. Chem. 277, 27872-27879.
6. Dhanabal, M., Ramchandran, R., Waterman, M. J., Lu, H., Knebelmann, B., Segal, M., and Sukhatme, V. P. (1999) Endostatin induces endothelial cell apoptosis, J. Biol. Chem. 274, 11721-11726.
7. MacDonald, N. J., Shivers, W. Y., Narum, D. L., Plum, S. M., Wingard, J. N., Fuhrmann, S. R., Liang, H., Holland-Linn, J., Chen, D. H., and Sim, B. K. (2001) Endostatin binds tropomyosin. A potential modulator of the antitumor activity of endostatin, J. Biol. Chem. 276, 25190-25196.
8. 1 integrin, a possible cause of prevention of chondrosarcoma growth, J. Biochem. 131, 619-626.
9. Rehn, M., Veikkola, T., Kukk-Valdre, E., Nakamura, H., Ilmonen, M., Lombardo, C., Pihlajaniemi, T., Alitalo, K., and Vuori, K. (2001) Interaction of endostatin with integrins implicated in angiogenesis, Proc. Natl. Acad. Sci. U.S.A. 98, 1024-1029.
10. Kim, Y. M., Jang, J. W., Lee, O. H., Yeon, J., Choi, E. Y., Kim, K. W., Lee, S. T., and Kwon, Y. G. (2000) Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase, Cancer Res. 60, 5410-5413.
11. Lee, S. J., Jang, J. W., Kim, Y. M., Lee, H. I., Jeon, J. Y., Kwon, Y. G., and Lee, S. T. (2002) Endostatin binds to the catalytic domain of matrix metalloproteinase-2, FEBS Lett. 519, 147-152.
12. Wickström, S. A., Veikkola, T., Rehn, M., Pihlajaniemi, T., Alitalo, K., and Keski-Oja, J. (2001) Endostatin-induced modulation of plasminogen activation with concomitant loss of focal adhesions and actin stress fibers in cultured human endothelial cells, Cancer Res. 67, 6511-6516.
13. Sasaki, T., Larsson, H., Kreuger, J., Salmivirta, M., Claesson-Welsh, L., Lindahl, U., Hohenester, E., and Timpl, R. (1999) Structural basis and potential role of heparin/heparin sulfate binding to the angiogenesis inhibitor endostatin, EMBO J. 18, 6240-6248.
14. Richard-Blum, S., Feraud, O., Lortat-Jacob, H. Rencurosi, A., Fukai, N., Dkhissi, F., Vittet, D., Imberty, A., Olsen, B. R., and van der Rest, M. (2004) Characterization of endostatin binding to heparin and heparin sulfate by surface plasmon resonance and molecular modeling, J. Biol. Chem. 279, 2927-2936.
15. Wickström, S. A., Alitalo, K., and Keski-Oja, J. (2003) Endostatin associates with lipid rafts and induces reorganization of the actin cytoskeleton via down-regulation of RhoA activity, J. Biol. Chem. 278, 37895-37901.
16. 1 and caveolin-1, and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells, Cancer Res. 62, 5580-5589.
17. Zhao, H., Mattila, J. P., Holopainen, J. M., and Kinnunen, P. K. J. (2001) Comparison of the membrane association of two antimicrobial peptides, magainin 2 and indolicidin, Biophys. J. 81, 2979-2991.
18. Zhao, H., Rinaldi, A. C., Di Giulio, A., Simmaco, M., and Kinnunen, P. K. J. (2002) Interaction of the antimicrobial peptides temporins with model biomembranes. Comparison of temporin B and L, Biochemistry 41, 4425-4436.
19. Wiedmer, S. K., Hautala, J., Holopainen, J. M., Kinnunen, P. K. J., and Riekkola, M.-L. (2001) Study on liposomes by capillary electrophoresis, Electrophoresis 22, 1305-1313.
20. Utsugi, T., Schroit, A. J., Connor, J., Bucana, C. D., and Fidler, I. J. (1991) Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes, Cancer Res. 51, 3062-3066.
21. Ran, S., and Thorpe, P. E. (2002) Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy, Int. J. Radiat. Oncol., Biol., Phys. 54, 1479-1484.
22. Momchilova, A., Ivanova, L., Markovska, T., and Pankov, R. (2000) Stimulated nonspecific transport of phospholipids results in elevated external appearance of phosphatidylserine in rastransformed fibroblasts, Arch. Biochem. Biophys. 381, 295-301.
23. Hohenester, E., Sasaki, T., Olsen, B. R., and Timpl, R. (1998) Crystal structure of the angiogenensis inhibitor endostatin at 1.5 Å resolution, EMBO J. 17, 1656-1664.
24. Menger, F. M. (1998) Giant vesicles: Imitating the cytological processes of cell membranes, Acc. Chem. Res. 31, 789-797.
25. Träuble, H. (1976) Membrane electrostatics, in Structure of Biological Membranes (Abrahamsson, S., and Pascher, I., Eds.) pp 509-550, Plenum, New York.
26. Rytömaa, M., and Kinnunen, P. K. J. (1994) Evidence for two distinct acidic phospholipid binding sites in cytochrome c, J. Biol. Chem. 269, 1770-1774.
27. Kranenburg, O., Kroon-Batenburg, L. M., Reijerkerk, A., Wu, Y. P., Voest, E. E., and Gebbink, M. F. (2003) Recombinant endostatin forms amyloid fibrils that bind and are cytotoxic to murine neuroblastoma cells in vitro, FEBS Lett. 539, 149-155.
28. Reijerkerk, A., Mosnier, L. O., Kranenburg, O., Bouma, B. N., Carmeliet, P., Drixler, T., Meijers, J. C. M., Voest, E. E., and Gebbink, M. F. B. G. (2003) Amyloid endostatin induces endothelial cell detachment by stimulation of the plasminogen activation system, Mol. Cancer Res. 1, 561-568.
29. Zhao, H., Bose, S., Tuominen, E. K. J., and Kinnunen, P. K. J. (2004) Interaction of histone H1 with phospholipids and comparison of its binding to giant liposomes and human leukemic T cells, Biochemistry 43, 10192-10202.
30. Zhao, H., Tuominen, E. K. J., and Kinnunen, P. K. J. (2004) Formation of amyloid fibers triggered by phosphatidylserine containing membranes, Biochemistry 43, 10302-10307.
31. Dobson, C. M. (2003) Protein folding and misfolding, Nature 426, 884-890.
32. Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo, Nature 416, 535-539.
33. Caughey, B., and Lansbury, P. T., Jr. (2003) Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders, Annu. Rev. Neurosci. 26, 267-298.
34. Halliday, B. E., Silverman, J. F., and Finley, J. L. (1998) Fine-needle aspiration cytology of amyloid associated with nonneoplastic and malignant lesions, Diagn. Cytopathol. 18, 270-275.
35. Sahoo, S., Reeves, W., and DeMay, R. M. (2003) Amyloid tumor: A clinical and cytomorphologic study, Diagn. Cytopathol. 28, 325-328.
36. Hancock, R. E. W., and Scott, M. G. (2000) The role of antimicrobial peptides in animal defences, Proc. Natl. Acad. Sci. U.S.A. 97, 8856-8861.
37. Volles, M. J., and Lansbury, P. T., Jr. (2002) Vesicle permeabilization by protofibrillar α-synuclein is sensitive to Parkinson's disease-related mutations and occurs by a pore-like mechanism, Biochemistry 41, 4595-4602.
38. Old, L. J. (1988) Tumor necrosis factor, Sci. Am. 258, 41-49.