-
1
-
-
0017670013
-
Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation
-
Paterson BM, Roberts BE, Kuff EL: Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation. Proc. Natl Acad. Sci. USA 74(10), 4370-4374 (1977).
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, Issue.10
, pp. 4370-4374
-
-
Paterson, B.M.1
Roberts, B.E.2
Kuff, E.L.3
-
2
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik PC, Stephenson ML: Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl Acad. Sci. USA 75(1), 280-284 (1978).
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, Issue.1
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
3
-
-
0005772676
-
Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide
-
Stephenson ML, Zamecnik PC: Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc. Natl Acad. Sci. USA 75(1), 285-288 (1978).
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, Issue.1
, pp. 285-288
-
-
Stephenson, M.L.1
Zamecnik, P.C.2
-
4
-
-
11144330098
-
Natural and engineered nucleic acids as tools to explore biology
-
Breaker RR: Natural and engineered nucleic acids as tools to explore biology. Nature 432(7019), 838-845 (2004).
-
(2004)
Nature
, vol.432
, Issue.7019
, pp. 838-845
-
-
Breaker, R.R.1
-
5
-
-
0032147234
-
Nucleic acid therapeutics: State of the art and future prospects
-
Gewirtz AM, Sokol DL, Ratajczak MZ: Nucleic acid therapeutics: state of the art and future prospects. Blood 92(3), 712-736 (1988).
-
(1988)
Blood
, vol.92
, Issue.3
, pp. 712-736
-
-
Gewirtz, A.M.1
Sokol, D.L.2
Ratajczak, M.Z.3
-
6
-
-
0028943759
-
Antigene, ribozyme and aptamer nucleic acid drugs: Progress and prospects
-
Stull RA, Szoka FC Jr: Antigene, ribozyme and aptamer nucleic acid drugs: progress and prospects. Pharm. Res. 12(4), 465-483 (1995).
-
(1995)
Pharm. Res.
, vol.12
, Issue.4
, pp. 465-483
-
-
Stull, R.A.1
Szoka Jr., F.C.2
-
7
-
-
0036636074
-
Nucleic-acid therapeutics: Basic principles and recent applications
-
Opalinska JB, Gewirtz AM: Nucleic-acid therapeutics: basic principles and recent applications. Nat. Rev. Drug Discov. 1(7), 503-514 (2002).
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, Issue.7
, pp. 503-514
-
-
Opalinska, J.B.1
Gewirtz, A.M.2
-
10
-
-
33645095226
-
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
-
Ng EWM, Shima DT, Calias P, Cunningham ET Jr, Guyer DR, Adamis AP: Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat. Rev. Drug Discov. 5(2), 123-132 (2006).
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, Issue.2
, pp. 123-132
-
-
Ng, E.W.M.1
Shima, D.T.2
Calias, P.3
Cunningham Jr., E.T.4
Guyer, D.R.5
Adamis, A.P.6
-
11
-
-
3242677639
-
SiRNAs: Applications in functional genomics and potential as therapeutics
-
Dorsett Y, Tuschl T: siRNAs: Applications in functional genomics and potential as therapeutics. Nat. Rev. Drug Discov. 3(4), 318-329 (2004).
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, Issue.4
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
12
-
-
34347391035
-
Utilizing RNA interference to enhance cancer drug discovery
-
Iorns E, Lord CJ, Turner N, Ashworth A: Utilizing RNA interference to enhance cancer drug discovery. Nat. Rev. Drug Discov. 6(7), 556-568 (2007).
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, Issue.7
, pp. 556-568
-
-
Iorns, E.1
Lord, C.J.2
Turner, N.3
Ashworth, A.4
-
13
-
-
33751099034
-
RNAi therapeutics: A potential new class of pharmaceutical drugs
-
Bumcrot D, Manoharan M, Koteliansky V, Sah DWY: RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat. Chem. Biol. 2(12), 711-719 (2006).
-
(2006)
Nat. Chem. Biol.
, vol.2
, Issue.12
, pp. 711-719
-
-
Bumcrot, D.1
Manoharan, M.2
Koteliansky, V.3
Sah, D.W.Y.4
-
14
-
-
33645500266
-
Progress towards in vivo use of siRNAs
-
Behlke MA: Progress towards in vivo use of siRNAs. Mol. Ther. 13(4), 644-670 (2006).
-
(2006)
Mol. Ther.
, vol.13
, Issue.4
, pp. 644-670
-
-
Behlke, M.A.1
-
15
-
-
33847036990
-
Strategies for silencing human disease using RNA interference
-
Kim DH, Rossi JJ: Strategies for silencing human disease using RNA interference. Nat. Rev. Genetics 8(3), 173-184 (2007).
-
(2007)
Nat. Rev. Genetics
, vol.8
, Issue.3
, pp. 173-184
-
-
Kim, D.H.1
Rossi, J.J.2
-
16
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
DOI 10.1038/35888
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391(6669), 806-811 (1998). (Pubitemid 28099681)
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
17
-
-
0034737298
-
RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
Zamore PD, Tuschl T, Sharp PA, Bartel DP: RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101(1), 25-33 (2000).
-
(2000)
Cell.
, vol.101
, Issue.1
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
18
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
DOI 10.1101/gad.862301
-
Elbashir SM, Lendeckel W, Tuschl T: RNA interference is mediated by 21-and 22-nucleotide RNAs. Genes Dev. 15(2), 188-200 (2001). (Pubitemid 32107664)
-
(2001)
Genes and Development
, vol.15
, Issue.2
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
19
-
-
0031657551
-
How cells respond to interferons
-
Stark GR, Kerr IM, Williams BRG, Silverman RH, Schreiber RD: How cells respond to interferons. Annu. Rev. Biochem. 67, 227-264 (1998).
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.G.3
Silverman, R.H.4
Schreiber, R.D.5
-
20
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411(6836), 494-498 (2001).
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
21
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez J, Patkaniowska A, Urlaub H, Lührmann R, Tuschl T: Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110(5), 563-574 (2002).
-
(2002)
Cell.
, vol.110
, Issue.5
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Lührmann, R.4
Tuschl, T.5
-
23
-
-
8844262560
-
RNA interference and chemically modified small interfering RNAs
-
Manoharan M: RNA interference and chemically modified small interfering RNAs. Curr. Opin. Chem. Biol. 8(6), 570-579 (2004).
-
(2004)
Curr. Opin. Chem. Biol.
, vol.8
, Issue.6
, pp. 570-579
-
-
Manoharan, M.1
-
24
-
-
33744458689
-
RNA interference with chemically modified siRNA
-
Zhang HY, Du Q, Wahlestedt C, Liang Z: RNA interference with chemically modified siRNA. Curr. Top. Med. Chem. 6(9), 893-900 (2006).
-
(2006)
Curr. Top. Med. Chem.
, vol.6
, Issue.9
, pp. 893-900
-
-
Zhang, H.Y.1
Du, Q.2
Wahlestedt, C.3
Liang, Z.4
-
25
-
-
61849162695
-
SiRNA conjugate delivery systems
-
Jeong JH, Mok H, Oh YK, Park TG: siRNA conjugate delivery systems. Bioconjugate Chem. 20, 5-14 (2009).
-
(2009)
Bioconjugate Chem.
, vol.20
, pp. 5-14
-
-
Jeong, J.H.1
Mok, H.2
Oh, Y.K.3
Park, T.G.4
-
26
-
-
67649865399
-
The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice
-
Gao S, Dagnaes-Hansen F, Nielsen EJB et al.: The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. Mol. Ther. 17(7), 1225-1233 (2009).
-
(2009)
Mol. Ther.
, vol.17
, Issue.7
, pp. 1225-1233
-
-
Gao, S.1
Dagnaes-Hansen, F.2
Nielsen, E.J.B.3
-
27
-
-
1242316928
-
Biodistribution of phosphodiester and phosphorothioate siRNA
-
Braasch DA, Paroo Z, Constantinescu A et al.: Biodistribution of phosphodiester and phosphorothioate siRNA. Bioorg. Med. Chem. Lett. 14(5), 1139-1143 (2004).
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, Issue.5
, pp. 1139-1143
-
-
Braasch, D.A.1
Paroo, Z.2
Constantinescu, A.3
-
28
-
-
60049097220
-
Efficient siRNA delivery with nonviral polymeric vehicles
-
Kim WJ, Kim SW: Efficient siRNA delivery with nonviral polymeric vehicles. Pharm. Res. 26(3), 657-666 (2008).
-
(2008)
Pharm. Res.
, vol.26
, Issue.3
, pp. 657-666
-
-
Kim, W.J.1
Kim, S.W.2
-
29
-
-
34548818764
-
Cationic lipids and polymers mediated vectors for delivery of siRNA
-
Zhang S, Zhao B, Jiang H, Wang B, Ma B: Cationic lipids and polymers mediated vectors for delivery of siRNA. J. Controlled Release 123(1), 1-10 (2007).
-
(2007)
J. Controlled Release
, vol.123
, Issue.1
, pp. 1-10
-
-
Zhang, S.1
Zhao, B.2
Jiang, H.3
Wang, B.4
Ma, B.5
-
30
-
-
22144447455
-
Design and development of polymers for gene delivery
-
Pack DW, Hoffman AS, Pun S, Stayton PS: Design and development of polymers for gene delivery. Nat. Rev. Drug Discov. 4(7), 581-593 (2005).
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, Issue.7
, pp. 581-593
-
-
Pack, D.W.1
Hoffman, A.S.2
Pun, S.3
Stayton, P.S.4
-
31
-
-
0031447208
-
DNA condensation by multivalent cations
-
Bloomfield VA: DNA condensation by multivalent cations. Biopolymers 44(3), 269-282 (1997).
-
(1997)
Biopolymers
, vol.44
, Issue.3
, pp. 269-282
-
-
Bloomfield, V.A.1
-
32
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
Boussif O, Lezoualc'h F, Zanta MA et al.: A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl Acad. Sci. USA 92(16), 7297-7301 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, Issue.16
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
-
33
-
-
78650476432
-
The proton sponge: A trick to enter cells the viruses did not exploit
-
Behr JP: The proton sponge: A trick to enter cells the viruses did not exploit. Chimia 51(1-2), 34-36 (1997).
-
(1997)
Chimia
, vol.51
, Issue.1-2
, pp. 34-36
-
-
Behr, J.P.1
-
34
-
-
0242414440
-
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
-
Sonawane ND, Szoka Jr. FC, Verkman AS: Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J. Biol. Chem. 278(45), 44826-44831 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.45
, pp. 44826-44831
-
-
Sonawane, N.D.1
Szoka Jr., F.C.2
Verkman, A.S.3
-
35
-
-
15444373116
-
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
-
Urban-Klein B, Werth S, Abuharbeid S, Czubayko F, Aigner A: RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther. 12(5), 461-466 (2005).
-
(2005)
Gene Ther.
, vol.12
, Issue.5
, pp. 461-466
-
-
Urban-Klein, B.1
Werth, S.2
Abuharbeid, S.3
Czubayko, F.4
Aigner, A.5
-
36
-
-
0035342007
-
Poly (amidoamine) (PAMAM) dendrimers: From biomimicry to drug delivery and biomedical applications
-
Esfand R, Tomalia DA: Poly (amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. Drug Discov. Today 6(8), 427-436 (2001).
-
(2001)
Drug Discov. Today
, vol.6
, Issue.8
, pp. 427-436
-
-
Esfand, R.1
Tomalia, D.A.2
-
38
-
-
33744914093
-
PAMAM dendrimers for efficient siRNA delivery and potent gene silencing
-
Zhou J, Wu J, Hafdi N, Behr JP, Erbacher P, Peng L: PAMAM dendrimers for efficient siRNA delivery and potent gene silencing. Chem. Commun. 2362-2364 (2006).
-
(2006)
Chem. Commun.
, pp. 2362-2364
-
-
Zhou, J.1
Wu, J.2
Hafdi, N.3
Behr, J.P.4
Erbacher, P.5
Peng, L.6
-
39
-
-
70349976881
-
In vivo siRNA delivery with dendritic poly (L-lysine) for the treatment of hypercholesterolemia
-
Watanabe K, Harada-Shiba M, Suzuki A et al.: In vivo siRNA delivery with dendritic poly (L-lysine) for the treatment of hypercholesterolemia. Mol. BioSyst. 5(11), 1306-1310 (2009).
-
(2009)
Mol. BioSyst
, vol.5
, Issue.11
, pp. 1306-1310
-
-
Watanabe, K.1
Harada-Shiba, M.2
Suzuki, A.3
-
40
-
-
70449700090
-
Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery
-
Taratula O, Garbuzenko OB, Kirkpatrick P et al.: Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery. J. Controlled Release 140(3), 284-293 (2009).
-
(2009)
J. Controlled Release
, vol.140
, Issue.3
, pp. 284-293
-
-
Taratula, O.1
Garbuzenko, O.B.2
Kirkpatrick, P.3
-
41
-
-
75149133614
-
Chitosan-based formulations for delivery of DNA and siRNA
-
Mao S, Sun W, Kissel T: Chitosan-based formulations for delivery of DNA and siRNA. Adv. Drug Deliv. Rev. 62, 12-27 (2010).
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 12-27
-
-
Mao, S.1
Sun, W.2
Kissel, T.3
-
42
-
-
33751419974
-
The influence of polymeric properties on chitosan-siRNA nanoparticle formulation and gene silencing
-
Liu X, Howard KA, Dong M et al.: The influence of polymeric properties on chitosan-siRNA nanoparticle formulation and gene silencing. Biomaterials 28, 1280-1288 (2007).
-
(2007)
Biomaterials
, vol.28
, pp. 1280-1288
-
-
Liu, X.1
Howard, K.A.2
Dong, M.3
-
43
-
-
33749844509
-
Development and characterisation of chitosan nanoparticles for siRNA delivery
-
Katas H, Alpar HO: Development and characterisation of chitosan nanoparticles for siRNA delivery. J. Controlled Release 115(2), 216-225 (2006).
-
(2006)
J. Controlled Release
, vol.115
, Issue.2
, pp. 216-225
-
-
Katas, H.1
Alpar, H.O.2
-
44
-
-
33748054817
-
RNA interference in vitro and in vivo using a chitosan-siRNA nanoparticle system
-
Howard KA, Rahbek UL, Liu X et al.: RNA interference in vitro and in vivo using a chitosan-siRNA nanoparticle system. Mol. Ther. 14, 476-484 (2006).
-
(2006)
Mol. Ther.
, vol.14
, pp. 476-484
-
-
Howard, K.A.1
Rahbek, U.L.2
Liu, X.3
-
45
-
-
0141927263
-
Stealth liposomes and long circulating nanoparticles: Critical issues in pharmacokinetics, opsonization and protein-binding properties
-
Moghimi SM, Szebeni J: Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog. Lipid Res. 42(6), 463-478 (2003).
-
(2003)
Prog. Lipid Res.
, vol.42
, Issue.6
, pp. 463-478
-
-
Moghimi, S.M.1
Szebeni, J.2
-
46
-
-
0037362655
-
Effect of PEGylation on pharmaceuticals
-
Harris JM, Chess RB: Effect of PEGylation on pharmaceuticals. Nat. Rev. Drug Discov. 2(3), 214-221 (2003).
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, Issue.3
, pp. 214-221
-
-
Harris, J.M.1
Chess, R.B.2
-
47
-
-
34250819325
-
Poly (ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery
-
van Vlerken LE, Vyas TK, Amiji MM: Poly (ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery. Pharm. Res. 24(8), 1405-1414 (2007).
-
(2007)
Pharm. Res.
, vol.24
, Issue.8
, pp. 1405-1414
-
-
Van Vlerken, L.E.1
Vyas, T.K.2
Amiji, M.M.3
-
48
-
-
34548644167
-
Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life
-
Sato A, Choi SW, Hirai M et al.: Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life. J. Controlled Release 122(3), 209-216 (2007).
-
(2007)
J. Controlled Release
, vol.122
, Issue.3
, pp. 209-216
-
-
Sato, A.1
Choi, S.W.2
Hirai, M.3
-
49
-
-
33750288634
-
Coronastabilized interpolyelectrolyte complexes of siRNA with nonimmunogenic, hydrophilic/cationic block copolymers prepared by aqueous RAFT polymerization
-
Scales CW, Huang F, Li N et al.: Coronastabilized interpolyelectrolyte complexes of siRNA with nonimmunogenic, hydrophilic/cationic block copolymers prepared by aqueous RAFT polymerization. Macromolecules 39(20), 6871-6881 (2006).
-
(2006)
Macromolecules
, vol.39
, Issue.20
, pp. 6871-6881
-
-
Scales, C.W.1
Huang, F.2
Li, N.3
-
50
-
-
0037428969
-
Effective drug delivery by PEGylated drug conjugates
-
Greenwald RB, Choe YH, McGuire J, Conover CD: Effective drug delivery by PEGylated drug conjugates. Adv. Drug Deliv. Rev. 55(2), 217-250 (2003).
-
(2003)
Adv. Drug Deliv. Rev.
, vol.55
, Issue.2
, pp. 217-250
-
-
Greenwald, R.B.1
Choe, Y.H.2
McGuire, J.3
Conover, C.D.4
-
51
-
-
26944452043
-
PEGylation, successful approach to drug delivery
-
Veronese FM, Pasut G: PEGylation, successful approach to drug delivery. Drug Discov. Today 10(21), 1451-1458 (2005).
-
(2005)
Drug Discov. Today
, vol.10
, Issue.21
, pp. 1451-1458
-
-
Veronese, F.M.1
Pasut, G.2
-
53
-
-
0037462992
-
PEGylated nanoparticles for biological and pharmaceutical applications
-
Otsuka H, Nagasaki Y, Kataoka K: PEGylated nanoparticles for biological and pharmaceutical applications. Adv. Drug. Deliv. Rev. 55(3), 403-419 (2003).
-
(2003)
Adv. Drug. Deliv. Rev.
, vol.55
, Issue.3
, pp. 403-419
-
-
Otsuka, H.1
Nagasaki, Y.2
Kataoka, K.3
-
54
-
-
0035937592
-
Block copolymer micelles for drug delivery: Design, characterization and biological significance
-
Kataoka K, Harada A, Nagasaki Y: Block copolymer micelles for drug delivery: design, characterization and biological significance. Adv. Drug. Deliv. Rev. 47(1), 113-131 (2001).
-
(2001)
Adv. Drug. Deliv. Rev.
, vol.47
, Issue.1
, pp. 113-131
-
-
Kataoka, K.1
Harada, A.2
Nagasaki, Y.3
-
55
-
-
0037148675
-
Block copolymer micelles for delivery of gene and related compounds
-
Kakizawa Y, Kataoka K: Block copolymer micelles for delivery of gene and related compounds. Adv. Drug. Deliv. Rev. 54(2), 203-222 (2002).
-
(2002)
Adv. Drug. Deliv. Rev.
, vol.54
, Issue.2
, pp. 203-222
-
-
Kakizawa, Y.1
Kataoka, K.2
-
56
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs
-
Matsumura Y, Maeda H: A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs. Cancer Res. 46(12), 6387-6392 (1986).
-
(1986)
Cancer Res.
, vol.46
, Issue.12
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
57
-
-
0034000453
-
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
-
Maeda H, Wu J, Sawa T, Matsumura Y, Hori K: Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control. Release 65(1-2), 271-284 (2000).
-
(2000)
J. Control. Release
, vol.65
, Issue.1-2
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Sawa, T.3
Matsumura, Y.4
Hori, K.5
-
58
-
-
33748994569
-
Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly (ethylene imine)-graft-poly (ethylene glycol) block copolymer/siRNA polyplexes
-
Mao S, Neu M, Germershaus O et al.: Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly (ethylene imine)-graft-poly (ethylene glycol) block copolymer/siRNA polyplexes. Bioconjugate Chem. 17(5), 1209-1218 (2006).
-
(2006)
Bioconjugate Chem.
, vol.17
, Issue.5
, pp. 1209-1218
-
-
Mao, S.1
Neu, M.2
Germershaus, O.3
-
59
-
-
61849103493
-
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI (-PEG)/siRNA complexes
-
Malek A, Merkel O, Fink L, Czubayko F, Kissel T, Aigner A: In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI (-PEG)/siRNA complexes. Toxicol. Appl. Pharm. 236(1), 97-108 (2009).
-
(2009)
Toxicol. Appl. Pharm.
, vol.236
, Issue.1
, pp. 97-108
-
-
Malek, A.1
Merkel, O.2
Fink, L.3
Czubayko, F.4
Kissel, T.5
Aigner, A.6
-
60
-
-
34249820576
-
Multifunctional nanocarriers
-
Torchilin VP: Multifunctional nanocarriers. Adv. Drug Deliv. Rev. 58(14), 1532-1555 (2006).
-
(2006)
Adv. Drug Deliv. Rev.
, vol.58
, Issue.14
, pp. 1532-1555
-
-
Torchilin, V.P.1
-
62
-
-
51049090204
-
Nanoparticle therapeutics: An emerging treatment modality for cancer
-
Davis ME, Chen Z, Shin DM: Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 7(9), 771-782 (2008).
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, Issue.9
, pp. 771-782
-
-
Davis, M.E.1
Chen, Z.2
Shin, D.M.3
-
63
-
-
14544298301
-
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
-
Schiffelers RM, Ansari A, Xu J et al.: Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res. 32(19), E149 (2004).
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.19
-
-
Schiffelers, R.M.1
Ansari, A.2
Xu, J.3
-
64
-
-
31544448890
-
Comparative evaluation of target-specific GFP gene silencing efficiencie for antisense ODN, synthetic siRNA, and siRNA plasmid complexed with PEI-PEG-FOL conjugate
-
Kim SH, Mok H, Jeong JH, Kim SW, Park TG: Comparative evaluation of target-specific GFP gene silencing efficiencie for antisense ODN, synthetic siRNA, and siRNA plasmid complexed with PEI-PEG-FOL conjugate. Bioconjugate Chem. 17(1), 241-244 (2007).
-
(2007)
Bioconjugate Chem.
, vol.17
, Issue.1
, pp. 241-244
-
-
Kim, S.H.1
Mok, H.2
Jeong, J.H.3
Kim, S.W.4
Park, T.G.5
-
65
-
-
1242292220
-
Partial acetylation of polyethylenimine enhances in vitro gene delivery
-
Forrest ML, Meister GE, Koerber JT, Pack DW: Partial acetylation of polyethylenimine enhances in vitro gene delivery. Pharm. Res. 21(2), 365-371 (2004)
-
(2004)
Pharm. Res.
, vol.21
, Issue.2
, pp. 365-371
-
-
Forrest, M.L.1
Meister, G.E.2
Koerber, J.T.3
Pack, D.W.4
-
66
-
-
0037069319
-
Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells
-
Thomas M, Klibanov AM: Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. Proc. Natl Acad. Sci. USA 99(23), 14640-14645 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.23
, pp. 14640-14645
-
-
Thomas, M.1
Klibanov, A.M.2
-
67
-
-
47749100430
-
Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity
-
Zintchenko A, Philipp A, Dehshahri A, Wagner E: Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity. Bioconjugate Chem. 19(7), 1448-1455 (2008).
-
(2008)
Bioconjugate Chem.
, vol.19
, Issue.7
, pp. 1448-1455
-
-
Zintchenko, A.1
Philipp, A.2
Dehshahri, A.3
Wagner, E.4
-
68
-
-
0034998969
-
Water-soluble lipopolymer for gene delivery
-
Han SO, Mahato RI, Kim SW: Water-soluble lipopolymer for gene delivery. Bioconjugate Chem. 12(3), 337-345 (2001).
-
(2001)
Bioconjugate Chem.
, vol.12
, Issue.3
, pp. 337-345
-
-
Han, S.O.1
Mahato, R.I.2
Kim, S.W.3
-
69
-
-
0345118151
-
Water-soluble lipopolymer as an efficient carrier for gene delivery to myocardium
-
DOI 10.1038/sj.gt.3301938
-
Lee M, Rentz J, Han SO, Bull DA, Kim SW: Water-soluble lipopolymer as an efficient carrier for gene delivery to myocardium. Gene Ther. 10(7), 585-593 (2003). (Pubitemid 36432610)
-
(2003)
Gene Therapy
, vol.10
, Issue.7
, pp. 585-593
-
-
Lee, M.1
Rentz, J.2
Han, S.-O.3
Bull, D.A.4
Kim, S.W.5
-
70
-
-
33947302736
-
Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy
-
Kim WJ, Chang CW, Lee M, Kim SW: Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy. J. Controlled Release 118(3), 357-363 (2007).
-
(2007)
J. Controlled Release
, vol.118
, Issue.3
, pp. 357-363
-
-
Kim, W.J.1
Chang, C.W.2
Lee, M.3
Kim, S.W.4
-
71
-
-
71249151558
-
Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery
-
Philipp A, Zhao X, Tarcha P, Wagner E, Zintchenko A: Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery. Bioconjugate Chem. 20(11), 2055-2061 (2009).
-
(2009)
Bioconjugate Chem.
, vol.20
, Issue.11
, pp. 2055-2061
-
-
Philipp, A.1
Zhao, X.2
Tarcha, P.3
Wagner, E.4
Zintchenko, A.5
-
72
-
-
73649089707
-
A highly efficient siRNA carrier of PBLG modified hyperbranched PEI
-
Chen J, Tian H, Guo Z et al.: A highly efficient siRNA carrier of PBLG modified hyperbranched PEI. Macromol. Biosci. 9 (12) 1247-1253 (2009).
-
(2009)
Macromol. Biosci
, vol.9
, Issue.12
, pp. 1247-1253
-
-
Chen, J.1
Tian, H.2
Guo, Z.3
-
73
-
-
34347346184
-
Synthesis and in vitro characterization of an ABC triblock copolymer for siRNA delivery
-
Segura T, Hubbell JA: Synthesis and in vitro characterization of an ABC triblock copolymer for siRNA delivery. Bioconjugate Chem. 18(3), 736-745 (2007).
-
(2007)
Bioconjugate Chem.
, vol.18
, Issue.3
, pp. 736-745
-
-
Segura, T.1
Hubbell, J.A.2
-
74
-
-
39749166238
-
Monomolecular assembly of siRNA and poly (ethylene glycol)-peptide copolymers
-
De Rouchey J, Schmidt C, Walker GF et al.: Monomolecular assembly of siRNA and poly (ethylene glycol)-peptide copolymers. Biomacromolecules 9(2), 724-732 (2008).
-
(2008)
Biomacromolecules
, vol.9
, Issue.2
, pp. 724-732
-
-
De Rouchey, J.1
Schmidt, C.2
Walker, G.F.3
-
75
-
-
54049107594
-
Biodegradable amphiphilic poly (ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery
-
Xiong XB, Uludaq H, Lavasanifar A: Biodegradable amphiphilic poly (ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery. Biomaterials 30(2), 242-253 (2009).
-
(2009)
Biomaterials
, vol.30
, Issue.2
, pp. 242-253
-
-
Xiong, X.B.1
Uludaq, H.2
Lavasanifar, A.3
-
76
-
-
75249090947
-
Cycloamylose-based biomaterial: Nanogel of cholesterol-bearing cationic cycloamylose for siRNA delivery
-
Toita A, Soma Y, Morimoto N, Akiyoshi K. Cycloamylose-based biomaterial: nanogel of cholesterol-bearing cationic cycloamylose for siRNA delivery. Chem. Lett. 38(11), 1114-1115 (2009).
-
(2009)
Chem. Lett.
, vol.38
, Issue.11
, pp. 1114-1115
-
-
Toita, A.1
Soma, Y.2
Morimoto, N.3
Akiyoshi, K.4
-
77
-
-
33746863376
-
Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma
-
Kim WJ, Christensen LV, Jo S et al.: Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma. Mol. Ther. 14(3), 343-350 (2006).
-
(2006)
Mol. Ther.
, vol.14
, Issue.3
, pp. 343-350
-
-
Kim, W.J.1
Christensen, L.V.2
Jo, S.3
-
78
-
-
6444243630
-
Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing
-
Itaka K, Kanayama N, Nishiyama N et al.: Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing. J. Am. Chem. Soc. 126(42), 13612-13613 (2004).
-
(2004)
J. Am. Chem. Soc.
, vol.126
, Issue.42
, pp. 13612-13613
-
-
Itaka, K.1
Kanayama, N.2
Nishiyama, N.3
-
79
-
-
31544456413
-
Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging
-
Bartlett DW, Davis ME: Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging. Nucleic Acids Res. 34(1), 322-333 (2006).
-
(2006)
Nucleic Acids Res.
, vol.34
, Issue.1
, pp. 322-333
-
-
Bartlett, D.W.1
Davis, M.E.2
-
80
-
-
67249128859
-
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic
-
Davis ME: The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic. Mol. Pharm. 6(3), 659-668 (2009).
-
(2009)
Mol. Pharm.
, vol.6
, Issue.3
, pp. 659-668
-
-
Davis, M.E.1
-
81
-
-
33947696667
-
Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles
-
Bartlett DW, Davis ME: Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles. Bioconjugate Chem. 18(2), 456-468 (2007).
-
(2007)
Bioconjugate Chem.
, vol.18
, Issue.2
, pp. 456-468
-
-
Bartlett, D.W.1
Davis, M.E.2
-
82
-
-
39549120024
-
Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles
-
Bartlett DW, Davis ME: Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles. Biotechnol. Bioeng. 99(4), 975-985 (2008).
-
(2008)
Biotechnol. Bioeng
, vol.99
, Issue.4
, pp. 975-985
-
-
Bartlett, D.W.1
Davis, M.E.2
-
83
-
-
35448973736
-
Breaking up the correlation between efficacy and toxicity for nonviral gene delivery
-
Breunig M, Lungwitz U, Liebl R, Goepferich A: Breaking up the correlation between efficacy and toxicity for nonviral gene delivery. Proc. Natl Acad. Sci. USA 104(36), 14454-14459 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.36
, pp. 14454-14459
-
-
Breunig, M.1
Lungwitz, U.2
Liebl, R.3
Goepferich, A.4
-
84
-
-
48749113674
-
Mechanistic investigation of poly (ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo
-
Breunig M, Hozsa C, Lungwitz U et al.: Mechanistic investigation of poly (ethylene imine)-based siRNA delivery: disulfide bonds boost intracellular release of the cargo. J. Controlled Release 130(1), 57-63 (2008).
-
(2008)
J. Controlled Release
, vol.130
, Issue.1
, pp. 57-63
-
-
Breunig, M.1
Hozsa, C.2
Lungwitz, U.3
-
86
-
-
67249165389
-
VEGF siRNA delivery system using arginine-grafted bioreducible poly (disulfide amine)
-
Kim SH, Jeong JH, Kim T, Kim SW, Bull DA: VEGF siRNA delivery system using arginine-grafted bioreducible poly (disulfide amine). Mol. Pharm. 6(3), 718-726 (2009).
-
(2009)
Mol. Pharm.
, vol.6
, Issue.3
, pp. 718-726
-
-
Kim, S.H.1
Jeong, J.H.2
Kim, T.3
Kim, S.W.4
Bull, D.A.5
-
87
-
-
34249825777
-
Synthesis and characterization of chemically condensed oligoethylenimine containing β-aminopropionamide linkages for siRNA delivery
-
Tarcha PJ, Pelisek J, Merdan T et al.: Synthesis and characterization of chemically condensed oligoethylenimine containing β-aminopropionamide linkages for siRNA delivery. Biomaterials 28(25), 3731-3740 (2007).
-
(2007)
Biomaterials
, vol.28
, Issue.25
, pp. 3731-3740
-
-
Tarcha, P.J.1
Pelisek, J.2
Merdan, T.3
-
88
-
-
47649089265
-
Induction of apoptosis in murine neuroblastoma by systemic delivery of transferrin-shielded siRNA polyplexes for downregulation of Ran
-
Tietze N, Pelisek J, Philipp A et al.: Induction of apoptosis in murine neuroblastoma by systemic delivery of transferrin-shielded siRNA polyplexes for downregulation of Ran. Oligonucleotides 18(2), 161-174 (2008).
-
(2008)
Oligonucleotides
, vol.18
, Issue.2
, pp. 161-174
-
-
Tietze, N.1
Pelisek, J.2
Philipp, A.3
-
89
-
-
40949100345
-
Poly (amino ester) as a carrier for si/shRNA delivery in lung cancer cells
-
Jere D, Xu CX, Arote R, Yun CH, Cho MH, Cho CS: Poly (amino ester) as a carrier for si/shRNA delivery in lung cancer cells. Biomaterials 29(16), 2535-2547 (2008).
-
(2008)
Biomaterials
, vol.29
, Issue.16
, pp. 2535-2547
-
-
Jere, D.1
Xu, C.X.2
Arote, R.3
Yun, C.H.4
Cho, M.H.5
Cho, C.S.6
-
90
-
-
63749103281
-
Acid-responsive linear polyethylenimine for efficient, specific, and biocompatible siRNA delivery
-
Shim MS, Kwon YJ: Acid-responsive linear polyethylenimine for efficient, specific, and biocompatible siRNA delivery. Bioconjugate Chem. 20(3), 488-499 (2009).
-
(2009)
Bioconjugate Chem.
, vol.20
, Issue.3
, pp. 488-499
-
-
Shim, M.S.1
Kwon, Y.J.2
-
91
-
-
58549112795
-
Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery
-
Matsumoto S, Christie RJ, Nishiyama N et al.: Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery. Biomacromolecules 10(1), 119-127 (2009).
-
(2009)
Biomacromolecules
, vol.10
, Issue.1
, pp. 119-127
-
-
Matsumoto, S.1
Christie, R.J.2
Nishiyama, N.3
-
92
-
-
13644254495
-
Lactosylated poly (ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive poly-ion complex micelles achieving enhanced gene silencing in hepatoma cells
-
Oishi M, Nagasaki Y, Itaka K, Nishiyama N, Kataoka K: Lactosylated poly (ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive poly-ion complex micelles achieving enhanced gene silencing in hepatoma cells. J. Am. Chem. Soc. 127(6), 1624-1625 (2005).
-
(2005)
J. Am. Chem. Soc.
, vol.127
, Issue.6
, pp. 1624-1625
-
-
Oishi, M.1
Nagasaki, Y.2
Itaka, K.3
Nishiyama, N.4
Kataoka, K.5
-
93
-
-
42149163566
-
Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly (ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes
-
Oishi M, Nagasaki Y, Nishiyama N et al.: Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly (ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes. Chem Bio Chem 2(9), 1290-1297 (2007).
-
(2007)
Chem. Bio. Chem.
, vol.2
, Issue.9
, pp. 1290-1297
-
-
Oishi, M.1
Nagasaki, Y.2
Nishiyama, N.3
-
94
-
-
0141838173
-
PH-responsive oligodeoxynucleotide (ODN)-poly (ethylene glycol) conjugate through acid-labile thiopropionate linkage: Preparation and poly-ion complex micelle formation
-
Oishi M, Sasaki S, Nagasaki Y, Kataoka K: pH-responsive oligodeoxynucleotide (ODN)-poly (ethylene glycol) conjugate through acid-labile thiopropionate linkage: Preparation and poly-ion complex micelle formation. Biomacromolecules 4(5), 1426-1432 (2003).
-
(2003)
Biomacromolecules
, vol.4
, Issue.5
, pp. 1426-1432
-
-
Oishi, M.1
Sasaki, S.2
Nagasaki, Y.3
Kataoka, K.4
-
95
-
-
0032472885
-
Receptor-mediated delivery of foreign genes to hepatocytes
-
Wu CH, Wu GY: Receptor-mediated delivery of foreign genes to hepatocytes. Adv. Drug Deliv. Rev. 29(3), 243-248 (1998).
-
(1998)
Adv. Drug Deliv. Rev.
, vol.29
, Issue.3
, pp. 243-248
-
-
Wu, C.H.1
Wu, G.Y.2
-
96
-
-
21044445774
-
Smart poly-ion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages
-
Oishi M, Nagatsugi F, Sasaki S, Nagasaki Y, Kataoka K: Smart poly-ion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages. Chem Bio Chem 6(4), 718-725 (2005).
-
(2005)
Chem. Bio Chem.
, vol.6
, Issue.4
, pp. 718-725
-
-
Oishi, M.1
Nagatsugi, F.2
Sasaki, S.3
Nagasaki, Y.4
Kataoka, K.5
-
97
-
-
33845216721
-
PEG conjugated VEGF siRNA for anti-angiogenic gene therapy
-
Kim SH, Jeong JH, Lee SH, Kim SW, Park TG: PEG conjugated VEGF siRNA for anti-angiogenic gene therapy. J. Controlled Release 116(2), 123-129 (2006).
-
(2006)
J. Controlled Release
, vol.116
, Issue.2
, pp. 123-129
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
98
-
-
34247153120
-
Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide
-
Lee SH, Kim SH, Park TG: Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide. Biochem. Biophys. Res. Commun. 357(2), 511-516 (2007).
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, Issue.2
, pp. 511-516
-
-
Lee, S.H.1
Kim, S.H.2
Park, T.G.3
-
99
-
-
46549085779
-
Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer
-
Kim SH, Jeong JH, Lee SH, Kim SW, Park TG: Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer. J. Controlled Release 129(2), 107-116 (2008).
-
(2008)
J. Controlled Release
, vol.129
, Issue.2
, pp. 107-116
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
100
-
-
41449109039
-
Breathing life into polycations: Functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery
-
Meyer M, Philipp A, Oskuee R, Schmidt C, Wagner E: Breathing life into polycations: Functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery. J. Am. Chem. Soc. 130(11), 3272-3273 (2008).
-
(2008)
J. Am. Chem. Soc.
, vol.130
, Issue.11
, pp. 3272-3273
-
-
Meyer, M.1
Philipp, A.2
Oskuee, R.3
Schmidt, C.4
Wagner, E.5
-
101
-
-
67249151969
-
Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate
-
Meyer M, Dohmen C, Philipp A et al.: Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate. Mol. Pharm. 6(3), 752-762 (2009).
-
(2009)
Mol. Pharm.
, vol.6
, Issue.3
, pp. 752-762
-
-
Meyer, M.1
Dohmen, C.2
Philipp, A.3
-
102
-
-
34248544999
-
Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels
-
Lee H, Mok H, Lee S, Oh YK, Park TG: Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels. J. Controlled Release 119(2), 245-252 (2007).
-
(2007)
J. Controlled Release
, vol.119
, Issue.2
, pp. 245-252
-
-
Lee, H.1
Mok, H.2
Lee, S.3
Oh, Y.K.4
Park, T.G.5
-
103
-
-
76249125385
-
Rational design of targeted cancer therapeutics through the multiconjugation of folate and cleavable siRNA to RAFT-synthesized (HPMA-s-APMA) copolymers
-
York AW, Huang F, McCormick CL: Rational design of targeted cancer therapeutics through the multiconjugation of folate and cleavable siRNA to RAFT-synthesized (HPMA-s-APMA) copolymers. Biomacromolecules 11(2), 505-514 (2010).
-
(2010)
Biomacromolecules
, vol.11
, Issue.2
, pp. 505-514
-
-
York, A.W.1
Huang, F.2
McCormick, C.L.3
-
104
-
-
47249085509
-
Reversible siRNA-polymer conjugates by RAFT polymerization
-
Heredia KL, Nguyen TH, Chang CW, Bulmus V, Davis TP, Maynard HD: Reversible siRNA-polymer conjugates by RAFT polymerization. Chem. Commun. 3245-3247 (2008).
-
(2008)
Chem. Commun.
, pp. 3245-3247
-
-
Heredia, K.L.1
Nguyen, T.H.2
Chang, C.W.3
Bulmus, V.4
Davis, T.P.5
Maynard, H.D.6
-
105
-
-
70349212212
-
Synthesis of dendritic carbohydrate end-functional polymers via RAFT: Versatile multifunctional precursors for bioconjugations
-
Xu J, Boyer C, Bulmus V, Davis TP: Synthesis of dendritic carbohydrate end-functional polymers via RAFT: Versatile multifunctional precursors for bioconjugations. J. Polym. Sci. A Polym. Chem. 47(17), 4302-4313 (2009).
-
(2009)
J. Polym. Sci. A Polym. Chem.
, vol.47
, Issue.17
, pp. 4302-4313
-
-
Xu, J.1
Boyer, C.2
Bulmus, V.3
Davis, T.P.4
-
106
-
-
34848918210
-
Impact of tumorspecific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging
-
Barlett DW, Su H, Hildebrandt IJ, Weber WA, Davis ME: Impact of tumorspecific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging. Proc. Natl Acad. Sci. USA 104(39), 15549-15554 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.39
, pp. 15549-15554
-
-
Barlett, D.W.1
Su, H.2
Hildebrandt, I.J.3
Weber, W.A.4
Davis, M.E.5
-
107
-
-
67651202350
-
Stability of siRNA polyplexes from poly (ethylenimine) and poly (ethylenimine) - G-poly (ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by fluorescence fluctuation spectroscopy and single photon emission computed tomography (SPECT) imaging
-
Merkel OM, Librizzi D, Pfestroff A et al.: Stability of siRNA polyplexes from poly (ethylenimine) and poly (ethylenimine) - g-poly (ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by fluorescence fluctuation spectroscopy and single photon emission computed tomography (SPECT) imaging. J. Controlled Release 138(2), 148-159 (2009).
-
(2009)
J. Controlled Release
, vol.138
, Issue.2
, pp. 148-159
-
-
Merkel, O.M.1
Librizzi, D.2
Pfestroff, A.3
-
108
-
-
77951237926
-
Stimuli-responsive smart nanogels for cancer diagnostics and therapy
-
Oishi M, Nagasaki Y: Stimuli-responsive smart nanogels for cancer diagnostics and therapy. Nanomedicine (Lond.) 5(3), 451-468 (2010).
-
(2010)
Nanomedicine (Lond.)
, vol.5
, Issue.3
, pp. 451-468
-
-
Oishi, M.1
Nagasaki, Y.2
-
109
-
-
67650444865
-
Enhanced cytoplasmic delivery of sirna using a stabilized poly-ion complexes based on PEGylated nanogels with a cross-linked polyamine structure
-
Tamura A, Oishi M, Nagasaki Y: Enhanced cytoplasmic delivery of sirna using a stabilized poly-ion complexes based on PEGylated nanogels with a cross-linked polyamine structure. Biomacromolecules 10(7), 1818-1827 (2009).
-
(2009)
Biomacromolecules
, vol.10
, Issue.7
, pp. 1818-1827
-
-
Tamura, A.1
Oishi, M.2
Nagasaki, Y.3
-
110
-
-
65249102723
-
Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles
-
Hu Y, Atukorale PU, Lu JJ et al.: Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles. Biomacromolecules 10(4), 756-765 (2009).
-
(2009)
Biomacromolecules
, vol.10
, Issue.4
, pp. 756-765
-
-
Hu, Y.1
Atukorale, P.U.2
Lu, J.J.3
-
111
-
-
66149148685
-
Biodegradable dextran nanogels for RNA interference: Focusing on endosomal escape and intracellular siRNA delivery
-
Raemdonck K, Naeye B, Buyens K et al.: Biodegradable dextran nanogels for RNA interference: Focusing on endosomal escape and intracellular siRNA delivery. Adv. Func. Mater. 19(9), 1406-1415 (2009).
-
(2009)
Adv. Func. Mater
, vol.19
, Issue.9
, pp. 1406-1415
-
-
Raemdonck, K.1
Naeye, B.2
Buyens, K.3
-
112
-
-
66149171496
-
Peptidefunctionalized nanogels for targeted siRNA delivery
-
Blackburn WH, Dickerson EB, Smith MH, McDonald JF, Lyon LA: Peptidefunctionalized nanogels for targeted siRNA delivery. Bioconjugate Chem. 20(5), 960-968 (2009).
-
(2009)
Bioconjugate Chem.
, vol.20
, Issue.5
, pp. 960-968
-
-
Blackburn, W.H.1
Dickerson, E.B.2
Smith, M.H.3
McDonald, J.F.4
Lyon, L.A.5
|