Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma

Biochemical Pharmacology

Volumn 80, Issue 10, 2010, Pages 1517-1527

  Pistollato, Francesca ^a   Abbadi, Sara ^a   Rampazzo, Elena ^a   Viola, Giampietro ^a   Puppa, Alessandro Della ^a   Cavallini, Lucia ^a   Frasson, Chiara ^a   Persano, Luca ^a   Panchision, David M ^b   Basso, Giuseppe ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

2 Deoxyglucose; GBM differentiation; Hypoxia; Hypoxia inducible factor 1 ; Prolyl hydroxylase 2

Indexed keywords

DEOXYGLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEASOME; GLUTATHIONE; HIF1A PROTEIN, HUMAN; OXYGEN; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE; SUCCINIC ACID;

APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; DOWN REGULATION; GLIOBLASTOMA; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; STEM CELL; TUMOR CELL LINE; ADULT; BRAIN; CELL ADHESION; CELL CULTURE; CELL SURVIVAL; CHILD; CULTURE TECHNIQUE; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADULT; APOPTOSIS; BLOTTING, WESTERN; BRAIN; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHILD; DEOXYGLUCOSE; GLIOBLASTOMA; GLUTATHIONE; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIAL, MITOCHONDRIAL; OXYGEN; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUCCINATE DEHYDROGENASE; SUCCINIC ACID;

EID: 77957016401     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.08.003     Document Type: Article

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