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Volumn 28, Issue 5, 2010, Pages 851-862

Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma

Author keywords

Cancer stem cells; Glioblastoma; Hypoxia; O6 methylguanine DNA methyltransferase; Smad1 5 8; Stat3; Temozolomide

Indexed keywords

BETA TUBULIN; CD133 ANTIGEN; MAMMALIAN TARGET OF RAPAMYCIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; STAT3 PROTEIN; TEMOZOLOMIDE;

EID: 77952330272     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.415     Document Type: Article
Times cited : (257)

References (45)
  • 2
    • 53449085011 scopus 로고    scopus 로고
    • Glioblastoma and stem cells
    • Altaner C. Glioblastoma and stem cells. Neoplasma 2008;55:369-374.
    • (2008) Neoplasma , vol.55 , pp. 369-374
    • Altaner, C.1
  • 3
    • 69249150466 scopus 로고    scopus 로고
    • Biological mechanisms of bevacizumab-associated adverse events
    • Higa GM, Abraham J. Biological mechanisms of bevacizumab-associated adverse events. Expert Rev Anticancer Ther 2009;9:999-1007.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 999-1007
    • Higa, G.M.1    Abraham, J.2
  • 4
    • 52749087584 scopus 로고    scopus 로고
    • Brain tumour stem cells: Implications for cancer therapy and regenerative medicine
    • Sanchez-Martin M. Brain tumour stem cells: Implications for cancer therapy and regenerative medicine. Curr Stem Cell Res Ther 2008;3:197-207.
    • (2008) Curr Stem Cell Res Ther , vol.3 , pp. 197-207
    • Sanchez-Martin, M.1
  • 5
    • 48649104080 scopus 로고    scopus 로고
    • Temozolomide preferentially depletes cancer stem cells in glioblastoma
    • Beier D, Rohrl S, Pillai DR et al. Temozolomide preferentially depletes cancer stem cells in glioblastoma. Cancer Res 2008;68:5706-5715.
    • (2008) Cancer Res , vol.68 , pp. 5706-5715
    • Beier, D.1    Rohrl, S.2    Pillai, D.R.3
  • 7
    • 46449115281 scopus 로고    scopus 로고
    • Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
    • Murat A, Migliavacca E, Gorlia T et al. Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. J Clin Oncol 2008;26:3015-3024.
    • (2008) J Clin Oncol , vol.26 , pp. 3015-3024
    • Murat, A.1    Migliavacca, E.2    Gorlia, T.3
  • 10
    • 70350314719 scopus 로고    scopus 로고
    • The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas
    • Discussion 875
    • Cao VT, Jung TY, Jung S et al. The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas. Neurosurgery 2009;65:866-875; Discussion 875.
    • (2009) Neurosurgery , vol.65 , pp. 866-875
    • Cao, V.T.1    Jung, T.Y.2    Jung, S.3
  • 14
    • 20444485232 scopus 로고    scopus 로고
    • -/- renal cancer
    • DOI 10.1158/0008-5472.CAN-05-0169
    • Smith K, Gunaratnam L, Morley M et al. Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer. Cancer Res 2005;65:5221-5230. (Pubitemid 40827332)
    • (2005) Cancer Research , vol.65 , Issue.12 , pp. 5221-5230
    • Smith, K.1    Gunaratnam, L.2    Morley, M.3    Franovic, A.4    Mekhail, K.5    Lee, S.6
  • 15
    • 65649115060 scopus 로고    scopus 로고
    • Hypoxia helps glioma to fight therapy
    • Amberger-Murphy V. Hypoxia helps glioma to fight therapy. Curr Cancer Drug Targets 2009;9:381-390.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 381-390
    • Amberger-Murphy, V.1
  • 17
    • 59849096400 scopus 로고    scopus 로고
    • Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma
    • Pistollato F, Chen HL, Rood BR et al. Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma. Stem Cell. 2009;27:7-17.
    • (2009) Stem Cell , vol.27 , pp. 7-17
    • Pistollato, F.1    Chen, H.L.2    Rood, B.R.3
  • 18
    • 67749142355 scopus 로고    scopus 로고
    • Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells
    • Pistollato F, Rampazzo E, Abbadi S et al. Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells. Plos One 2009;4:e6206.
    • (2009) Plos One , vol.4
    • Pistollato, F.1    Rampazzo, E.2    Abbadi, S.3
  • 19
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li Z, Bao S, Wu Q et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009;15:501-513.
    • (2009) Cancer Cell , vol.15 , pp. 501-513
    • Li, Z.1    Bao, S.2    Wu, Q.3
  • 20
    • 70449687092 scopus 로고    scopus 로고
    • Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha
    • Soeda A, Park M, Lee D et al. Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha. Oncogene 2009;28:3949-3959.
    • (2009) Oncogene , vol.28 , pp. 3949-3959
    • Soeda, A.1    Park, M.2    Lee, D.3
  • 21
    • 65049084510 scopus 로고    scopus 로고
    • Distinct pools of cancer stemlike cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution
    • Piccirillo SG, Combi R, Cajola L et al. Distinct pools of cancer stemlike cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution. Oncogene 2009;28:1807-1811.
    • (2009) Oncogene , vol.28 , pp. 1807-1811
    • Piccirillo, S.G.1    Combi, R.2    Cajola, L.3
  • 22
    • 51649117107 scopus 로고    scopus 로고
    • Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
    • Hegi ME, Liu L, Herman JG et al. Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol 2008;26:4189-4199.
    • (2008) J Clin Oncol , vol.26 , pp. 4189-4199
    • Hegi, M.E.1    Liu, L.2    Herman, J.G.3
  • 24
    • 34347226670 scopus 로고    scopus 로고
    • Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes
    • DOI 10.1016/j.mcn.2007.04.003, PII S1044743107000887
    • Pistollato F, Chen HL, Schwartz PH et al. Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes. Mol Cell Neurosci 2007;35:424-435. (Pubitemid 46992832)
    • (2007) Molecular and Cellular Neuroscience , vol.35 , Issue.3 , pp. 424-435
    • Pistollato, F.1    Chen, H.-L.2    Schwartz, P.H.3    Basso, G.4    Panchision, D.M.5
  • 26
    • 70349570410 scopus 로고    scopus 로고
    • HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms
    • Marin-Hernandez A, Gallardo-Perez JC, Ralph SJ et al. HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms. Mini Rev Med Chem 2009;9:1084-1101.
    • (2009) Mini Rev Med Chem , vol.9 , pp. 1084-1101
    • Marin-Hernandez, A.1    Gallardo-Perez, J.C.2    Ralph, S.J.3
  • 27
    • 64249126758 scopus 로고    scopus 로고
    • Expression of transmembrane carbonic anhydrases, Caix and CAXII, in human development
    • Liao SY, Lerman MI, Stanbridge EJ. Expression of transmembrane carbonic anhydrases, Caix And CAXII, in human development. BMC Dev Biol 2009;9:22.
    • (2009) BMC Dev Biol , vol.9 , pp. 22
    • Liao, S.Y.1    Lerman, M.I.2    Stanbridge, E.J.3
  • 29
    • 63049097582 scopus 로고    scopus 로고
    • Glial vascular endothelial growth factor overexpression in rat brainstem under tolerable hypoxia: Evidence for a central chemosensitivity
    • Perrin JS, Araneda S, Catteau J et al. Glial vascular endothelial growth factor overexpression in rat brainstem under tolerable hypoxia: Evidence for a central chemosensitivity. J Neurosci Res 2009;87:79-85.
    • (2009) J Neurosci Res , vol.87 , pp. 79-85
    • Perrin, J.S.1    Araneda, S.2    Catteau, J.3
  • 30
    • 0032806820 scopus 로고    scopus 로고
    • Astrocyte differentiation mediated by LIF in cooperation with BMP2
    • DOI 10.1016/S0014-5793(99)00997-7, PII S0014579399009977
    • Nakashima K, Yanagisawa M, Arakawa H et al. Astrocyte differentiation mediated by LIF in cooperation with BMP2. FEBS Lett 1999;457:43-46. (Pubitemid 29388176)
    • (1999) FEBS Letters , vol.457 , Issue.1 , pp. 43-46
    • Nakashima, K.1    Yanagisawa, M.2    Arakawa, H.3    Taga, T.4
  • 32
    • 0344735881 scopus 로고    scopus 로고
    • Cancerous stem cells can arise from pediatric brain tumors
    • Hemmati HD, Nakano I, Lazareff JA et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA 2003;100:15178-15183.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15178-15183
    • Hemmati, H.D.1    Nakano, I.2    Lazareff, J.A.3
  • 33
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya T, Morrison SJ, Clarke MF et al. Stem cells, cancer, and cancer stem cells. Nature 2001;414:105-111.
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3
  • 34
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh SK, Hawkins C, Clarke ID et al. Identification of human brain tumour initiating cells. Nature 2004;432:396-401.
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 35
    • 11244293572 scopus 로고    scopus 로고
    • Isolation of cancer stem cells from adult glioblastoma multiforme
    • Yuan X, Curtin J, Xiong Y et al. Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 2004;23:9392-9400.
    • (2004) Oncogene , vol.23 , pp. 9392-9400
    • Yuan, X.1    Curtin, J.2    Xiong, Y.3
  • 36
    • 68249157942 scopus 로고    scopus 로고
    • Glioblastoma stem cells resistant to temozolomide-induced autophagy
    • Engl
    • Fu J, Liu ZG, Liu XM et al. Glioblastoma stem cells resistant to temozolomide-induced autophagy. Chin Med J (Engl) 2009;122:1255-1259.
    • (2009) Chin Med J , vol.122 , pp. 1255-1259
    • Fu, J.1    Liu, Z.G.2    Liu, X.M.3
  • 37
    • 69349095324 scopus 로고    scopus 로고
    • CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines
    • McCord AM, Jamal M, Williams ES et al. CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines. Clin Cancer Res 2009;15:5145-5153.
    • (2009) Clin Cancer Res , vol.15 , pp. 5145-5153
    • McCord, A.M.1    Jamal, M.2    Williams, E.S.3
  • 38
    • 34547126890 scopus 로고    scopus 로고
    • Optimized flow cytometric analysis of central nervous system tissue reveals novel functional relationships among cells expressing CD133, CD15, and CD24
    • DOI 10.1634/stemcells.2006-0260
    • Panchision DM, Chen HL, Pistollato F et al. Optimized flow cytometric analysis of central nervous system tissue reveals novel functional relationships among cells expressing CD133, CD15, and CD24 Stem Cells 2007;25:1560-1570. (Pubitemid 47106026)
    • (2007) Stem Cells , vol.25 , Issue.6 , pp. 1560-1570
    • Panchision, D.M.1    Chen, H.-L.2    Pistollato, F.3    Papini, D.4    Ni, H.-T.5    Hawley, T.S.6
  • 39
    • 0942266264 scopus 로고    scopus 로고
    • O6-benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in anaplastic gliomas
    • Schold SC Jr., Kokkinakis DM, Chang SM et al. O6-benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in anaplastic gliomas. Neuro Oncol 2004;6:28-32.
    • (2004) Neuro Oncol , vol.6 , pp. 28-32
    • Schold Jr., S.C.1    Kokkinakis, D.M.2    Chang, S.M.3
  • 42
    • 34648821254 scopus 로고    scopus 로고
    • Making a tumour's bed: Glioblastoma stem cells and the vascular niche
    • Gilbertson RJ, Rich JN. Making a tumour's bed: Glioblastoma stem cells and the vascular niche. Nat Rev Cancer 2007;7:733-736.
    • (2007) Nat Rev Cancer , vol.7 , pp. 733-736
    • Gilbertson, R.J.1    Rich, J.N.2
  • 43
    • 77649273107 scopus 로고    scopus 로고
    • Hypoxia inducible factors in cancer stem cells
    • Heddleston JM, Li Z, Lathia JD et al. Hypoxia inducible factors in cancer stem cells. Br J Cancer 2;102:789-795.
    • Br J Cancer , vol.2 , Issue.102 , pp. 789-795
    • Heddleston, J.M.1    Li, Z.2    Lathia, J.D.3
  • 44
    • 70350225829 scopus 로고    scopus 로고
    • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
    • Heddleston JM, Li Z, McLendon RE et al. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 2009;8:3274-3284.
    • (2009) Cell Cycle , vol.8 , pp. 3274-3284
    • Heddleston, J.M.1    Li, Z.2    McLendon, R.E.3
  • 45
    • 68549104117 scopus 로고    scopus 로고
    • The role of oxygen in regulating neural stem cells in development and disease
    • Panchision DM. The role of oxygen in regulating neural stem cells in development and disease. J Cell Physiol 2009;220:562-568.
    • (2009) J Cell Physiol , vol.220 , pp. 562-568
    • Panchision, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.