Hypoxia and HIF1α repress the differentiative effects of BMPs in high-grade glioma

Stem Cells

Volumn 27, Issue 1, 2009, Pages 7-17

  Pistollato, Francesca ^a,b   Chen, Hui Ling ^b   Rood, Brian R ^b   Zhang, Hui Zhen ^b,c   D'Avella, Domenico ^a   Denaro, Luca ^a   Gardiman, Marina ^a   Te Kronnie, Geertruy ^a   Schwartz, Philip H ^d   Favaro, Elena ^a   Indraccolo, Stefano ^e   Basso, Giuseppe ^a   Panchision, David M ^b,f  

^a UNIVERSITY OF PADOVA   (Italy)

^b CHILDREN S RESEARCH INSTITUTE   (United States)

^c Children's Hospital   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^f NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Bone morphogenetic proteins; Brain tumor; High grade glioma; Hypoxia inducible factor 1 ; Oxygen; Smad

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN P53; SMAD PROTEIN; OXYGEN;

ARTICLE; CANCER GRADING; CANCER STEM CELL; CELL EXPANSION; CONTROLLED STUDY; GENE SILENCING; GLIOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOCYTOCHEMISTRY; MITOSIS INHIBITION; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; OXYGEN TENSION; PROTEIN EXPRESSION; SOLID TUMOR; ASTROCYTE; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; CHILD; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; GENETICS; METABOLISM; MITOSIS; PATHOLOGY; SIGNAL TRANSDUCTION;

ASTROCYTES; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; CHILD; DOWN-REGULATION; GENE SILENCING; GLIOMA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MITOSIS; NEOPLASTIC STEM CELLS; OXYGEN; SIGNAL TRANSDUCTION; SMAD PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 59849096400     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2008-0402     Document Type: Article

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