-
1
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nature Rev Neurosci 2003; 4: 49-60.
-
(2003)
Nature Rev Neurosci
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
3
-
-
0024352110
-
Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation
-
Klunk WE; Pettegrew JW, Abraham D.J. Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation. J Histochem Cytochem 1989; 37: 1273-1281.
-
(1989)
J Histochem Cytochem
, vol.37
, pp. 1273-1281
-
-
Klunk, W.E.1
Pettegrew, J.W.2
Abraham, D.J.3
-
4
-
-
0024509805
-
Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1
-
Naiki H, Higuchi K, Hosokawa M, Takeda T. Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1. Anal Biochem 1989; 177: 244-249.
-
(1989)
Anal Biochem
, vol.177
, pp. 244-249
-
-
Naiki, H.1
Higuchi, K.2
Hosokawa, M.3
Takeda, T.4
-
5
-
-
0032883766
-
Impairment of membrane transport and signal transduction systems by amyloidogenic proteins
-
Mattson MP. Impairment of membrane transport and signal transduction systems by amyloidogenic proteins. Methods Enzymol 1999; 309: 733-768.
-
(1999)
Methods Enzymol
, vol.309
, pp. 733-768
-
-
Mattson, M.P.1
-
6
-
-
34548726211
-
Generic cell dysfunction in neurodegenerative disorders: Role of surfaces in early protein misfolding, aggregation, and aggregate cytotoxicity
-
Stefani M. Generic cell dysfunction in neurodegenerative disorders: role of surfaces in early protein misfolding, aggregation, and aggregate cytotoxicity. Neuroscientist 2007; 13: 519-531.
-
(2007)
Neuroscientist
, vol.13
, pp. 519-531
-
-
Stefani, M.1
-
7
-
-
0026524681
-
Evidence for changes in the Alzheimer's disease brain cortical membrane structure mediated by cholesterol
-
Mason RP, Shoemaker WJ, Shajenko L, Chambers TE, Herbette LG. Evidence for changes in the Alzheimer's disease brain cortical membrane structure mediated by cholesterol. Aging 1992; 13: 413-419.
-
(1992)
Aging
, vol.13
, pp. 413-419
-
-
Mason, R.P.1
Shoemaker, W.J.2
Shajenko, L.3
Chambers, T.E.4
Herbette, L.G.5
-
8
-
-
14844321855
-
Cholesterol homeostasis failure as a unifying cause of synaptic degeneration
-
Koudinov AL, Koudinova NV. Cholesterol homeostasis failure as a unifying cause of synaptic degeneration. J Neurol Sci 2005; 229: 233-240.
-
(2005)
J Neurol Sci
, vol.229
, pp. 233-240
-
-
Koudinov, A.L.1
Koudinova, N.V.2
-
9
-
-
31644446183
-
Cholesterol and Alzheimer's disease-is there a relation?
-
Sjögren M, Mielke M, Gustafson D, Zandi P, Skoog I. Cholesterol and Alzheimer's disease-is there a relation? Mech Ageing Dev 2006;127:138-147.
-
(2006)
Mech Ageing Dev
, vol.127
, pp. 138-147
-
-
Sjögren, M.1
Mielke, M.2
Gustafson, D.3
Zandi, P.4
Skoog, I.5
-
10
-
-
58149220667
-
Cholesterol in Alzheimer's Disease: Unresolved Questions
-
Stefani M, Liguri G. Cholesterol in Alzheimer's Disease: Unresolved Questions. Curr Alzh Res 2009; 6: 15-29.
-
(2009)
Curr Alzh Res
, vol.6
, pp. 15-29
-
-
Stefani, M.1
Liguri, G.2
-
11
-
-
0036793543
-
Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AßP (1-40) and (1-42) peptides
-
Arispe N, Doh M. Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AßP (1-40) and (1-42) peptides. FASEB J 2002; 16: 1526-1536.
-
(2002)
FASEB J
, vol.16
, pp. 1526-1536
-
-
Arispe, N.1
Doh, M.2
-
12
-
-
0036752519
-
Protein misfolding in Alzheimer's and Parkinson's disease: Genetics and molecular mechanisms
-
Forloni G, Terreni L, Bertani I, et al. Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms. Neurobiol Aging 2002; 23: 957-976.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 957-976
-
-
Forloni, G.1
Terreni, L.2
Bertani, I.3
-
14
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
-
Kojro E, Gimpl G, Lammich S, März W, Fahrenholz F. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10. Proc Natl Acad Sci USA 2001; 98: 5815-5820.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
März, W.4
Fahrenholz, F.5
-
15
-
-
10344263931
-
Neuronal membrane cholesterol loss enhances amyloid peptide generation
-
Abad-Rodriguez J, Ledesma MD, Craessaerts K, et al. Neuronal membrane cholesterol loss enhances amyloid peptide generation. J Cell Biol (2004; 167: 953-960.
-
(2004)
J Cell Biol
, vol.167
, pp. 953-960
-
-
Abad-Rodriguez, J.1
Ledesma, M.D.2
Craessaerts, K.3
-
16
-
-
31444454174
-
The role of seladin- 1/DHCR24 in cholesterol biosynthesis, APP processing and Aβ generation in vivo
-
Crameri A, Biondi E, Kuehnle K, et al. The role of seladin- 1/DHCR24 in cholesterol biosynthesis, APP processing and Aβ generation in vivo. EMBO J 2006; 25: 432-443.
-
(2006)
EMBO J
, vol.25
, pp. 432-443
-
-
Crameri, A.1
Biondi, E.2
Kuehnle, K.3
-
17
-
-
64949147821
-
Central nervous system: Cholesterol turnover, brain development and neurodegeneration
-
Dietschy JM. Central nervous system: cholesterol turnover, brain development and neurodegeneration. Biol Chem 2009; 390: 287-293.
-
(2009)
Biol Chem
, vol.390
, pp. 287-293
-
-
Dietschy, J.M.1
-
18
-
-
1442308949
-
Adipocyte cholesterol balance in obesity
-
Le Lay S, Ferre P, Dugail I. Adipocyte cholesterol balance in obesity. Biochem Soc Trans 2004; 32: 103-106.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 103-106
-
-
Le, L.S.1
Ferre, P.2
Dugail, I.3
-
19
-
-
0036667737
-
Insights into lipid raft structure and formation from experiments in model membranes
-
London E. Insights into lipid raft structure and formation from experiments in model membranes. Curr Opin Struc Biol 2002; 12: 480-486.
-
(2002)
Curr Opin Struc Biol
, vol.12
, pp. 480-486
-
-
London, E.1
-
22
-
-
0025065068
-
Regulation of phospholipid biosynthesis during cholesterol influx and high density lipoprotein-mediated cholesterol efflux in macrophages
-
Schmitz G, Beuck M, Fischer H, Nowicka G, Robenek H. Regulation of phospholipid biosynthesis during cholesterol influx and high density lipoprotein-mediated cholesterol efflux in macrophages. J Lipid Res 1990; 31: 1741-1752.
-
(1990)
J Lipid Res
, vol.31
, pp. 1741-1752
-
-
Schmitz, G.1
Beuck, M.2
Fischer, H.3
Nowicka, G.4
Robenek, H.5
-
23
-
-
0032817267
-
Sphingomyelin and related lipids: Structure, occurrence, biosynthesis and analysis
-
Ridgway ND, Byers DM, Cook HW, Storey MK. Sphingomyelin and related lipids: structure, occurrence, biosynthesis and analysis. Prog Lipid Res 1999; 38: 337-360.
-
(1999)
Prog Lipid Res
, vol.38
, pp. 337-360
-
-
Ridgway, N.D.1
Byers, D.M.2
Cook, H.W.3
Storey, M.K.4
-
24
-
-
2542488501
-
Lipid rafts-protein association and the regulation of protein activity
-
Lucero HA, Robbins PW. Lipid rafts-protein association and the regulation of protein activity. Arch Biochem Biophys 2004; 426: 208-224.
-
(2004)
Arch Biochem Biophys
, vol.426
, pp. 208-224
-
-
Lucero, H.A.1
Robbins, P.W.2
-
25
-
-
0042160147
-
Both raft- and non-raft proteins associate with CHAPS-insoluble complexes: Some APP in large complexes
-
Rouvinski A, Gahali-Sassa I, Stavb I, et al. Both raft- and non-raft proteins associate with CHAPS-insoluble complexes: some APP in large complexes. Biochem Biophys Res Com 2003; 308: 750-758.
-
(2003)
Biochem Biophys Res Com
, vol.308
, pp. 750-758
-
-
Rouvinski, A.1
Gahali-Sassa, I.2
Stavb, I.3
-
26
-
-
0036733578
-
Cholesterol, lipid rafts, and disease
-
Simons K, Ehehalt R. Cholesterol, lipid rafts, and disease. J Clin Invest 2002; 110: 597-603.
-
(2002)
J Clin Invest
, vol.110
, pp. 597-603
-
-
Simons, K.1
Ehehalt, R.2
-
27
-
-
31844442585
-
-
Pani and Dessì Eds., New York, NY, USA: Kluwer Academic/Plenum Publisher
-
Dessi S, Batetta B. In: Cell Growth and Cholesterol Esters; Pani and Dessì Eds. New York, NY, USA: Kluwer Academic/Plenum Publisher 2004; pp 1-10.
-
(2004)
Cell Growth and Cholesterol Esters
, pp. 1-10
-
-
Dessi, S.1
Batetta, B.2
-
28
-
-
33748428356
-
-
Pani and Dessì Eds. New York, NY, USA: Kluwer Academic/Plenum Publisher
-
Dessi S, Batetta B. In: Cell Growth and Cholesterol Esters; Pani and Dessì Eds. New York, NY, USA: Kluwer Academic/Plenum Publisher 2004; pp 25-33.
-
(2004)
Cell Growth and Cholesterol Esters
, pp. 25-33
-
-
Dessi, S.1
Batetta, B.2
-
29
-
-
0015890890
-
Familial hypercholesteroleia: Identification of a defect in the regulation of 3-hydroxy-3- methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol
-
Goldstein JL, Brown MS. Familial hypercholesteroleia: Identification of a defect in the regulation of 3-hydroxy-3- methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. Proc Natl Acad Sci USA 1973; 70: 2804-2808.
-
(1973)
Proc Natl Acad Sci USA
, vol.70
, pp. 2804-2808
-
-
Goldstein, J.L.1
Brown, M.S.2
-
30
-
-
0013321009
-
Familial hypercholesterolemia: Defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
-
Brown MS, Goldstein JL. Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. Proc Natl Acad Sci USA 1974; 71: 788-792.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 788-792
-
-
Brown, M.S.1
Goldstein, J.L.2
-
31
-
-
0022549920
-
A receptor-mediated pathway for cholesterol homeostasis
-
Brown MS, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science 1986; 232: 34-47.
-
(1986)
Science
, vol.232
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
32
-
-
0034604350
-
Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes
-
Nohturfft A, Yabe D, Goldstein JL, Brown MS, Espenshade PJ. Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes. Cell 2000; 102: 315-323.
-
(2000)
Cell
, vol.102
, pp. 315-323
-
-
Nohturfft, A.1
Yabe, D.2
Goldstein, J.L.3
Brown, M.S.4
Espenshade, P.J.5
-
33
-
-
0037162719
-
Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
-
Yang T, Espenshade PJ, Wright ME, et al. Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 2002; 110: 489-500.
-
(2002)
Cell
, vol.110
, pp. 489-500
-
-
Yang, T.1
Espenshade, P.J.2
Wright, M.E.3
-
34
-
-
33745307534
-
The life cycle of neutral lipids: Synthesis, storage and degradation
-
Athenstaedt K, Daum G. The life cycle of neutral lipids: synthesis, storage and degradation. Cell Mol Life Sci 2006; 63: 1355-1369.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 1355-1369
-
-
Athenstaedt, K.1
Daum, G.2
-
35
-
-
76049095353
-
Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N- terminal sequence
-
Igarashi M, Osuga J, Isshiki M, et al. Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N- terminal sequence. J Lipid Res 2010; 51: 274-285.
-
(2010)
J Lipid Res
, vol.51
, pp. 274-285
-
-
Igarashi, M.1
Osuga, J.2
Isshiki, M.3
-
36
-
-
0036424016
-
Cholesterol trafficking in the secretory and endocytic systems
-
Prinz W. Cholesterol trafficking in the secretory and endocytic systems. Sem Cell Dev Biol 2002; 13: 197-203.
-
(2002)
Sem Cell Dev Biol
, vol.13
, pp. 197-203
-
-
Prinz, W.1
-
37
-
-
28444479505
-
Role of cholesterol and lipid organization in disease
-
Maxfield FR, Tabas I. Role of cholesterol and lipid organization in disease. Nature 2005; 438: 36-45.
-
(2005)
Nature
, vol.438
, pp. 36-45
-
-
Maxfield, F.R.1
Tabas, I.2
-
38
-
-
33646168160
-
Lipid droplets: A unified view of a dynamic organelle
-
Martin S, Parton RG. Lipid droplets: a unified view of a dynamic organelle. Nature Rev Mol Cell Biol 2006; 7: 373-378.
-
(2006)
Nature Rev Mol Cell Biol
, vol.7
, pp. 373-378
-
-
Martin, S.1
Parton, R.G.2
-
39
-
-
61549115335
-
A role for lipid droplets in inter-membrane lipid traffic
-
Zehmer JK, Huang Y, Peng G, et al. A role for lipid droplets in inter-membrane lipid traffic. Proteomics 2009; 9: 914-921.
-
(2009)
Proteomics
, vol.9
, pp. 914-921
-
-
Zehmer, J.K.1
Huang, Y.2
Peng, G.3
-
40
-
-
0035289932
-
Macrophage foam cells and atherosclerosis
-
Kruth HS. Macrophage foam cells and atherosclerosis. Front Biosci 2001; 6: 429-455.
-
(2001)
Front Biosci
, vol.6
, pp. 429-455
-
-
Kruth, H.S.1
-
41
-
-
53149099668
-
Regulated association of caveolins to lipid droplets during differentiation of 3T3-L1 adipocytes
-
Blouin CM, Le LS, Lasnier F, Dugail I, Hajduch E. Regulated association of caveolins to lipid droplets during differentiation of 3T3-L1 adipocytes. Biochem Biophys Res Commun 2008; 376: 331-335.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 331-335
-
-
Blouin, C.M.1
Le, L.S.2
Lasnier, F.3
Dugail, I.4
Hajduch, E.5
-
42
-
-
0035809931
-
Caveolin-2 is targeted to lipid droplets, a new "membrane domain" in the cell
-
Fujimoto T, Kogo H, Ishiguro K, Tauchi K, Nomura R. Caveolin-2 is targeted to lipid droplets, a new "membrane domain" in the cell. J Cell Biol 2001; 152: 1079-1085.
-
(2001)
J Cell Biol
, vol.152
, pp. 1079-1085
-
-
Fujimoto, T.1
Kogo, H.2
Ishiguro, K.3
Tauchi, K.4
Nomura, R.5
-
43
-
-
33846678695
-
The ABCA subfamily-gene and protein structures, functions and associated hereditary diseases
-
Albrecht C, Viturro EP. The ABCA subfamily-gene and protein structures, functions and associated hereditary diseases. Pflugers Arch 2007; 453: 581-589.
-
(2007)
Pflugers Arch
, vol.453
, pp. 581-589
-
-
Albrecht, C.1
Viturro, E.P.2
-
46
-
-
0035949487
-
Presenilin, Notch, and the genesis and treatment of Alzheimer's disease
-
Selkoe DJ. Presenilin, Notch, and the genesis and treatment of Alzheimer's disease. Proc Natl Acad Sci USA 2001; 98: 11039-11041.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11039-11041
-
-
Selkoe, D.J.1
-
47
-
-
0034049944
-
Proteolytic processing and cell biological functions of the amyloid precursor protein
-
De Strooper B, Annaert W. Proteolytic processing and cell biological functions of the amyloid precursor protein. J Cell Sci 2000; 113: 1857-1870.
-
(2000)
J Cell Sci
, vol.113
, pp. 1857-1870
-
-
de Strooper, B.1
Annaert, W.2
-
48
-
-
0035943345
-
A portrait of Alzheimer secretases-new features and familiar faces
-
Esler WP, Wolfe MS. A portrait of Alzheimer secretases-new features and familiar faces. Science 2001; 293: 1449-1454.
-
(2001)
Science
, vol.293
, pp. 1449-1454
-
-
Esler, W.P.1
Wolfe, M.S.2
-
49
-
-
0034644836
-
Regulation of APP cleavage by α-, β- and γ- secretases
-
Nunan J, Small DH. Regulation of APP cleavage by α-, β- and γ- secretases. FEBS Lett 2000; 483: 6-10.
-
(2000)
FEBS Lett
, vol.483
, pp. 6-10
-
-
Nunan, J.1
Small, D.H.2
-
51
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K. Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J Cell Biol 2003; 160: 113-123.
-
(2003)
J Cell Biol
, vol.160
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
52
-
-
0032802332
-
Cellular biology of prion diseases
-
Harris DA. Cellular biology of prion diseases. Clin Microbiol Rev 1999; 12: 429-444.
-
(1999)
Clin Microbiol Rev
, vol.12
, pp. 429-444
-
-
Harris, D.A.1
-
53
-
-
0025991466
-
The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive
-
Caughey B, Raymond GJ. The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive. J Biol Chem 1991; 266: 18217-18223.
-
(1991)
J Biol Chem
, vol.266
, pp. 18217-18223
-
-
Caughey, B.1
Raymond, G.J.2
-
54
-
-
13244295520
-
The highways and byways of prion protein trafficking
-
Campana V, Sarnataro D, Zurzolo C. The highways and byways of prion protein trafficking. Trends Cell Biol 2005; 15: 102-111.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 102-111
-
-
Campana, V.1
Sarnataro, D.2
Zurzolo, C.3
-
56
-
-
77957936778
-
-
Springer Link
-
Legname G, DeArmond SJ, Cohen FE; Prusiner SB. (2007) Coll. Biomed. Life Sci. Springer Link, 6, 125-146.
-
(2007)
Coll. Biomed. Life Sci.
, vol.6
, pp. 125-146
-
-
Legname, G.1
Dearmond, S.J.2
Cohen, F.E.3
Prusiner, S.B.4
-
58
-
-
0035168351
-
Prion diseases: What is the neurotoxic molecule?
-
Chiesa R, Harris DA. Prion diseases: what is the neurotoxic molecule? Neurobiol Dis 2001; 8: 743-763.
-
(2001)
Neurobiol Dis
, vol.8
, pp. 743-763
-
-
Chiesa, R.1
Harris, D.A.2
-
59
-
-
0027405573
-
Processing of a cellular prion protein: Identification of N- and C-terminal cleavage sites
-
Harris DA, Huber MT, van Dijken P, et al. Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites. Biochemistry 1993; 32: 1009-1016.
-
(1993)
Biochemistry
, vol.32
, pp. 1009-1016
-
-
Harris, D.A.1
Huber, M.T.2
van Dijken, P.3
-
60
-
-
0031765769
-
Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues
-
Jimenez-Huete A, Lievens PMJ, Vidal R, et al. Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. Am J Pathol 1998; 153: 1561-1572.
-
(1998)
Am J Pathol
, vol.153
, pp. 1561-1572
-
-
Jimenez-Huete, A.1
Lievens, P.M.J.2
Vidal, R.3
-
61
-
-
42149140619
-
Regulation of beta APP and PrPc cleavage by alpha-secretase: Mechanistic and therapeutic perspectives
-
Vincent B, Cisse MA, Sunyach C, Guillot-Sestier MV, Checler F. Regulation of beta APP and PrPc cleavage by alpha-secretase: mechanistic and therapeutic perspectives. Curr Alzheimer Res 2008; 5: 202-211.
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 202-211
-
-
Vincent, B.1
Cisse, M.A.2
Sunyach, C.3
Guillot-Sestier, M.V.4
Checler, F.5
-
62
-
-
18044377435
-
Roles of proteolysis and lipid rafts in the processing of the amyloid precursor protein and prion protein
-
Hooper NM. Roles of proteolysis and lipid rafts in the processing of the amyloid precursor protein and prion protein. Biochem Soc Trans 2005; 33: 335-338.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 335-338
-
-
Hooper, N.M.1
-
63
-
-
0033636136
-
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
-
Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 2000; 28: 449-459.
-
(2000)
Neuron
, vol.28
, pp. 449-459
-
-
Kamal, A.1
Stokin, G.B.2
Yang, Z.3
Xia, C.H.4
Goldstein, L.S.5
-
64
-
-
9144274938
-
Amyloid-beta degradation: The forgotten half of Alzheimer's disease
-
Whitaker C, Eckman C, Almeida C, et al. Amyloid-beta degradation: the forgotten half of Alzheimer's disease. J Alzheimer Dis 2003; 5: 491-497.
-
(2003)
J Alzheimer Dis
, vol.5
, pp. 491-497
-
-
Whitaker, C.1
Eckman, C.2
Almeida, C.3
-
65
-
-
34547400403
-
Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein
-
Parkin ET, Watt NT, Hussain I, et al. Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein. Proc Natl Acad Sci USA 2007; 104: 11062-11067.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 11062-11067
-
-
Parkin, E.T.1
Watt, N.T.2
Hussain, I.3
-
66
-
-
34347215068
-
Prion protein and prion diseases: The good and the bad
-
Malcolm J, Gains A, LeBlanc AC. Prion protein and prion diseases: the good and the bad. Can J Neurol Sci 2007; 34: 126-145.
-
(2007)
Can J Neurol Sci
, vol.34
, pp. 126-145
-
-
Malcolm, J.1
Gains, A.2
Leblanc, A.C.3
-
68
-
-
15544374091
-
The conflicting role of brain cholesterol in Alzheimer's disease: Lessons from the brain plasminogen system
-
Ledesma MD, Dotti CG. The conflicting role of brain cholesterol in Alzheimer's disease: lessons from the brain plasminogen system. Biochem Soc Symp 2005; 72: 129-138.
-
(2005)
Biochem Soc Symp
, vol.72
, pp. 129-138
-
-
Ledesma, M.D.1
Dotti, C.G.2
-
69
-
-
34547315810
-
Alzheimer's Disease: Cholesterol, membrane rafts, isoprenoids and statins
-
Reid PC, Urano Y, Kodama T, Hamakubo T. Alzheimer's Disease: cholesterol, membrane rafts, isoprenoids and statins. J Cell Mol Med 2007; 11: 383-392.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 383-392
-
-
Reid, P.C.1
Urano, Y.2
Kodama, T.3
Hamakubo, T.4
-
70
-
-
0028966735
-
Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform
-
Taraboulos, A, Scott M, Semenov A, et al. Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. J Cell Biol 1995; 129: 121-32.
-
(1995)
J Cell Biol
, vol.129
, pp. 121-132
-
-
Taraboulos, A.1
Scott, M.2
Semenov, A.3
-
71
-
-
2442483932
-
Squalestatin cures prion-infected neurons and protects against prion neurotoxicity
-
Bate C, Salmona M, Diomede L, Williams A. Squalestatin cures prion-infected neurons and protects against prion neurotoxicity. J Biol Chem 2004; 279: 14983-14990.
-
(2004)
J Biol Chem
, vol.279
, pp. 14983-14990
-
-
Bate, C.1
Salmona, M.2
Diomede, L.3
Williams, A.4
-
72
-
-
33746890495
-
Simvastatin prolongs survival times in prion infections of the central nervous system
-
Mok SW, Thelen KM, Riemer C, et al. Simvastatin prolongs survival times in prion infections of the central nervous system. Biochem Biophys Res Commun 2006; 348: 697-702.
-
(2006)
Biochem Biophys Res Commun
, vol.348
, pp. 697-702
-
-
Mok, S.W.1
Thelen, K.M.2
Riemer, C.3
-
73
-
-
34247589262
-
Simvastatin treatment prolongs the survival of scrapie-infected mice
-
Kempster S, Bate C, Williams A. Simvastatin treatment prolongs the survival of scrapie-infected mice. Neuroreport 2006; 18: 479-482.
-
(2006)
Neuroreport
, vol.18
, pp. 479-482
-
-
Kempster, S.1
Bate, C.2
Williams, A.3
-
74
-
-
33846821715
-
Cholesterol synthesis inhibitors protect against platelet-activating factor-induced neuronal damage
-
Doi:10.1186/1742-2094-4-5
-
Bate C, Rumbold L, Williams A. Cholesterol synthesis inhibitors protect against platelet-activating factor-induced neuronal damage. J Neuroinflam 2007, 4:5. Doi:10.1186/1742-2094-4-5.
-
(2007)
J Neuroinflam
, vol.4
, pp. 5
-
-
Bate, C.1
Rumbold, L.2
Williams, A.3
-
75
-
-
45149109366
-
Induced neuroprotection independently from PrPSc accumulation in a mouse model for prion disease treated with simvastatin
-
Haviv Y, Avrahami D, Ovadia H, et al. Induced neuroprotection independently from PrPSc accumulation in a mouse model for prion disease treated with simvastatin. Arch Neurol 2008; 65: 762-773.
-
(2008)
Arch Neurol
, vol.65
, pp. 762-773
-
-
Haviv, Y.1
Avrahami, D.2
Ovadia, H.3
-
76
-
-
63149151206
-
A systems approach to prion disease
-
Doi:10.1038/msb
-
Hwang D, Lee IY, Yoo H, et al. A systems approach to prion disease. Mol Syst Biol 2009; 5:252. Doi:10.1038/msb.2009.10.
-
(2009)
Mol Syst Biol
, vol.5
, pp. 252
-
-
Hwang, D.1
Lee, I.Y.2
Yoo, H.3
-
77
-
-
42149186322
-
Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes
-
Doi:10.1186/1471-2164-9-114
-
Sorensen G, Medina S, Parchaliuk D, et al. Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes. BMC Genom 2008; 9:114. Doi:10.1186/1471-2164-9-114.
-
(2008)
BMC Genom
, vol.9
, pp. 114
-
-
Sorensen, G.1
Medina, S.2
Parchaliuk, D.3
Et al.4
-
78
-
-
71449102371
-
Prion-induced activation of cholesterogenic gene expression by SREBP2 in neuronal cells
-
Bach, C.; Gilch S.; Rost R, et al. Prion-induced activation of cholesterogenic gene expression by SREBP2 in neuronal cells. J Biol Chem 2009; 284: 31260-31269.
-
(2009)
J Biol Chem
, vol.284
, pp. 31260-31269
-
-
Bach, C.1
Gilch, S.2
Rost, R.3
-
79
-
-
0034638746
-
Statins and the risk of dementia
-
Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman DA. Statins and the risk of dementia. Lancet 2000; 356: 1627-1631.
-
(2000)
Lancet
, vol.356
, pp. 1627-1631
-
-
Jick, H.1
Zornberg, G.L.2
Jick, S.S.3
Seshadri, S.4
Drachman, D.A.5
-
81
-
-
22844431778
-
Statin use and the risk of incident dementia: The cardiovascular health study
-
Rea TD, Breitner JC, Psaty BM. Statin use and the risk of incident dementia: the cardiovascular health study. Arch Neurol 2005; 62: 1047-1051.
-
(2005)
Arch Neurol
, vol.62
, pp. 1047-1051
-
-
Rea, T.D.1
Breitner, J.C.2
Psaty, B.M.3
-
82
-
-
34249825804
-
Effect of HMG-CoA Reductase Inhibitors on [beta]-Amyloid Peptide Levels: Implications For Alzheimer's Disease
-
Höglund K, Blennow K. Effect of HMG-CoA Reductase Inhibitors on [beta]-Amyloid Peptide Levels: Implications for Alzheimer's Disease. CNS Drugs 2007; 21: 449-462.
-
(2007)
CNS Drugs
, vol.21
, pp. 449-462
-
-
Höglund, K.1
Blennow, K.2
-
83
-
-
34548291482
-
Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease
-
Li G, Larson EB, Sonnen JA, et al. Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease. Neurology 2007; 69: 878-885.
-
(2007)
Neurology
, vol.69
, pp. 878-885
-
-
Li, G.1
Larson, E.B.2
Sonnen, J.A.3
-
84
-
-
43249094747
-
Statins, incident Alzheimer disease, change in cognitive function, and neuro- pathology
-
Arvanitakis Z, Schneider JA, Wilson RS, et al. Statins, incident Alzheimer disease, change in cognitive function, and neuro- pathology. Neurology 2008; 70: 1795-1802.
-
(2008)
Neurology
, vol.70
, pp. 1795-1802
-
-
Arvanitakis, Z.1
Schneider, J.A.2
Wilson, R.S.3
-
86
-
-
65049089153
-
Statins: Mechanisms of neuroprotection
-
van der Most PJ, Dolga AM, Nijholt IM, Luiten PGM, Eise ULM. Statins: Mechanisms of neuroprotection. Prog Neurobiol 2009; 88: 64-75.
-
(2009)
Prog Neurobiol
, vol.88
, pp. 64-75
-
-
van der Most, P.J.1
Dolga, A.M.2
Nijholt, I.M.3
Luiten, P.G.M.4
Eise, U.L.M.5
-
87
-
-
33845892752
-
Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
-
Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE. Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet 2007; 39: 17-23.
-
(2007)
Nat Genet
, vol.39
, pp. 17-23
-
-
Bertram, L.1
McQueen, M.B.2
Mullin, K.3
Blacker, D.4
Tanzi, R.E.5
-
88
-
-
10744223627
-
Genetic association of acyl-coenzyme A: Cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer's disease
-
Wollmer MA, Streffer JR, Tsolaki M, et al. Genetic association of acyl-coenzyme A: cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer's disease. Mol Psychiatry 2003; 8: 635-638.
-
(2003)
Mol Psychiatry
, vol.8
, pp. 635-638
-
-
Wollmer, M.A.1
Streffer, J.R.2
Tsolaki, M.3
-
89
-
-
5144227934
-
The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease
-
Hutter-Paier B, Huttunen HJ, Puglielli L, et al. The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease. Neuron 2004; 44: 227-238.
-
(2004)
Neuron
, vol.44
, pp. 227-238
-
-
Hutter-Paier, B.1
Huttunen, H.J.2
Puglielli, L.3
-
90
-
-
34047268145
-
Knockdown of ACAT-1 reduces amyloidogenic processing of APP
-
Huttunen HJ, Greco C, Kovacs DM. Knockdown of ACAT-1 reduces amyloidogenic processing of APP. FEBS Lett 2007; 581: 1688-1692.
-
(2007)
FEBS Lett
, vol.581
, pp. 1688-1692
-
-
Huttunen, H.J.1
Greco, C.2
Kovacs, D.M.3
-
91
-
-
40449110086
-
ACAT as a drug target for Alzheimer's disease
-
Huttunen HJ, Kovacs DM. ACAT as a drug target for Alzheimer's disease. Neurodegener Dis 2008; 5: 212-214.
-
(2008)
Neurodegener Dis
, vol.5
, pp. 212-214
-
-
Huttunen, H.J.1
Kovacs, D.M.2
-
93
-
-
38849086036
-
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease
-
Wahrle SE, Jiang H, Parsadanian M, et al. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest 2008; 118: 671-682.
-
(2008)
J Clin Invest
, vol.118
, pp. 671-682
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
-
94
-
-
74949103451
-
Altered cholesterol ester cycle in skin fibroblasts from patients with Alzheimer's disease
-
Pani A, Dessì S, Diaz G, et al. Altered cholesterol ester cycle in skin fibroblasts from patients with Alzheimer's disease. J Alzheimer Dis 2009; 18: 829-841.
-
(2009)
J Alzheimer Dis
, vol.18
, pp. 829-841
-
-
Pani, A.1
Dessì, S.2
Diaz, G.3
-
95
-
-
70749123387
-
Accumulation of neutral lipids in peripheral blood mononuclear cells as a distintive trait of Alzheimer patients and asymptomatic subjects at risk of disease
-
Doi:10.1186/1741-7015-7-66
-
[95] Pani A, Mandas A, Diaz G, et al. Accumulation of neutral lipids in peripheral blood mononuclear cells as a distintive trait of Alzheimer patients and asymptomatic subjects at risk of disease. BMC Med 2009; 7: 66. Doi:10.1186/1741-7015-7-66.
-
(2009)
BMC Med
, vol.7
, pp. 66
-
-
Pani, A.1
Mandas, A.2
Diaz, G.3
-
96
-
-
35848930063
-
Accumulation of cholesterol esters in ex vivo lymphocytes from scrapie-susceptible sheep and in scrapie-infected mouse neuroblastoma cell lines
-
Pani A, Norfo C, Abete C, et al. Accumulation of cholesterol esters in ex vivo lymphocytes from scrapie-susceptible sheep and in scrapie-infected mouse neuroblastoma cell lines. Am J Infect Dis 2007; 3: 165-168.
-
(2007)
Am J Infect Dis
, vol.3
, pp. 165-168
-
-
Pani, A.1
Norfo, C.2
Abete, C.3
-
97
-
-
70049118212
-
Cholesterol metabolism in brain and skin fibroblasts from sarda breed sheep with scrapie-resistant and scrapie-susceptible genotypes
-
Pani A, Abete C, Norfo C, et al. Cholesterol metabolism in brain and skin fibroblasts from sarda breed sheep with scrapie-resistant and scrapie-susceptible genotypes. Am J Infect Dis 2007; 3:143-150.
-
(2007)
Am J Infect Dis
, vol.3
, pp. 143-150
-
-
Pani, A.1
Abete, C.2
Norfo, C.3
-
98
-
-
75849161806
-
ACAT, Cav1 and PrP expression in scrapie susceptible and resistant sheep
-
Orrù CD, Abete C, Cannas MD, et al. ACAT, Cav1 and PrP expression in scrapie susceptible and resistant sheep. Cent Eur J Biol 2010; 5: 31-37.
-
(2010)
Cent Eur J Biol
, vol.5
, pp. 31-37
-
-
Orrù, C.D.1
Abete, C.2
Cannas, M.D.3
-
99
-
-
41549105318
-
Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospho- lipase A2 activation
-
Doi:10.1186/1741-7007-6-8
-
Bate B, Tayebi M, Williams A. Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospho- lipase A2 activation. BMC Biol 2008; 6: 8. Doi:10.1186/1741-7007-6-8.
-
(2008)
BMC Biol
, vol.6
, pp. 8
-
-
Bate, B.1
Tayebi, M.2
Williams, A.3
-
100
-
-
35848936977
-
Anti-prion activity of cholesterol esterification modulators: A comparative study in ex vivo sheep fibroblasts and lymphocytes and in mouse neuroblastoma cell lines
-
Pani A, Norfo C, Abete C, et al. Anti-prion activity of cholesterol esterification modulators: a comparative study in ex vivo sheep fibroblasts and lymphocytes and in mouse neuroblastoma cell lines. Antimicrob Agents Chemother 2007; 51: 4141-4147.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 4141-4147
-
-
Pani, A.1
Norfo, C.2
Abete, C.3
-
101
-
-
77952096872
-
In vitro synergistic anti- prion effect of cholesterol ester modulators in combination with chlorpromazine and quinacrine
-
Orrù CD, Cannas MD, Vascellari S, et al. In vitro synergistic anti- prion effect of cholesterol ester modulators in combination with chlorpromazine and quinacrine. Cent Eur J Biol 2010; 5: 151-165.
-
(2010)
Cent Eur J Biol
, vol.5
, pp. 151-165
-
-
Orrù, C.D.1
Cannas, M.D.2
Vascellari, S.3
-
102
-
-
36749073968
-
Cell division modulates prion accumulation in cultured cells
-
Ghaemmaghami S, Phuan PW, Perkins B, et al. Cell division modulates prion accumulation in cultured cells. Proc Natl Acad Sci USA 2007; 104: 17971-17976.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 17971-17976
-
-
Ghaemmaghami, S.1
Phuan, P.W.2
Perkins, B.3
-
106
-
-
0034987223
-
Roles of acylcoenzyme A:Cholesterol acyltransferase-1 and -2
-
Chang TY, Chang CC, Lin S, et al. Roles of acylcoenzyme A:cholesterol acyltransferase-1 and -2. Curr Opin Lipidol 2001; 12: 289-296.
-
(2001)
Curr Opin Lipidol
, vol.12
, pp. 289-296
-
-
Chang, T.Y.1
Chang, C.C.2
Lin, S.3
-
107
-
-
41849091490
-
Intraventricular pentosan polysulphate in human prion diseases: An observational study in the UK
-
Bone I, Belton L, Walker AS, Darbyshire J. Intraventricular pentosan polysulphate in human prion diseases: an observational study in the UK. Eur J Neurol 2008; 15: 458-464.
-
(2008)
Eur J Neurol
, vol.15
, pp. 458-464
-
-
Bone, I.1
Belton, L.2
Walker, A.S.3
Darbyshire, J.4
-
108
-
-
0035908839
-
Old drugs to treat new variant Creutzfeldt-Jakob disease
-
Love R. Old drugs to treat new variant Creutzfeldt-Jakob disease. Lancet 2001; 358: 563-574.
-
(2001)
Lancet
, vol.358
, pp. 563-574
-
-
Love, R.1
-
110
-
-
77954558825
-
Alzheimer's disease therapeutic research: The path forward
-
Doi:10.1186/alzrt2
-
Aisen PS. Alzheimer's disease therapeutic research: the path forward. Alzh Res Ther 2009; 1:2. Doi:10.1186/alzrt2
-
(2009)
Alzh Res Ther
, vol.1
, pp. 2
-
-
Aisen, P.S.1
-
111
-
-
62149105940
-
Safety and efficacy of quinacrine in human prion disease (PRION-1 study): A patient- preference trial
-
Collinge J, Gorham M, Hudson F, et al. Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient- preference trial. Lancet Neurol 2009; 8: 334-344.
-
(2009)
Lancet Neurol
, vol.8
, pp. 334-344
-
-
Collinge, J.1
Gorham, M.2
Hudson, F.3
-
112
-
-
67649795561
-
Recent advances in prion chemotherapeutics
-
Sim VL, Caughey B. Recent advances in prion chemotherapeutics. Infect Dis Drug Targets 2009; 9: 81-91.
-
(2009)
Infect Dis Drug Targets
, vol.9
, pp. 81-91
-
-
Sim, V.L.1
Caughey, B.2
-
114
-
-
33745926817
-
Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments
-
Klingenstein R, Lober S, Kujala P, et al. Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments. J Neurochem 2006; 98: 748-759.
-
(2006)
J Neurochem
, vol.98
, pp. 748-759
-
-
Klingenstein, R.1
Lober, S.2
Kujala, P.3
-
115
-
-
0034001444
-
Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation
-
Doh-ura K, Iwaki T, Caughey B. Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation. J Virol 2000; 74: 4894-4897.
-
(2000)
J Virol
, vol.74
, pp. 4894-4897
-
-
Doh-Ura, K.1
Iwaki, T.2
Caughey, B.3
-
116
-
-
33750980390
-
Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS- related cell lines: Marked differences between various antipsychotic drugs
-
Fernø J, Skrede S, Vik-Mo AO, Havic B, Steen VD. Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS- related cell lines: marked differences between various antipsychotic drugs. BMC Neurosci 2006; 7: 69-80.
-
(2006)
BMC Neurosci
, vol.7
, pp. 69-80
-
-
Fernø, J.1
Skrede, S.2
Vik-Mo, A.O.3
Havic, B.4
Steen, V.D.5
-
117
-
-
70350719357
-
Psychotropic drugs up- regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells
-
Doi:10.1186/1471-2210-9-10
-
Vik-Mo AO, Fernø J, Skrede S, Steen VM. Psychotropic drugs up- regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells. BMC Pharmacol 2009; 9:10. Doi:10.1186/1471-2210-9-10.
-
(2009)
BMC Pharmacol
, vol.9
, pp. 10
-
-
Vik-Mo, A.O.1
Fernø, J.2
Skrede, S.3
Steen, V.M.4
-
118
-
-
20844435988
-
Effects of sirolimus on mesangial cell cholesterol homeostasis: A novel mechanism for its action against lipid-mediated injury in renal allografts
-
Varghese Z, Fernando R, Moorhead JF, Powis SH, Ruan XZ. Effects of sirolimus on mesangial cell cholesterol homeostasis: a novel mechanism for its action against lipid-mediated injury in renal allografts. Am J Physiol Renal Physiol 2005; 289: 43-48.
-
(2005)
Am J Physiol Renal Physiol
, vol.289
, pp. 43-48
-
-
Varghese, Z.1
Fernando, R.2
Moorhead, J.F.3
Powis, S.H.4
Ruan, X.Z.5
-
119
-
-
0027096635
-
Progesterone blocks cholesterol translocation from lysosomes
-
Butler JD, Banchette-Mackie J, Golden E, et al. Progesterone blocks cholesterol translocation from lysosomes. J Biol Chem 1992; 267: 23797-23805.
-
(1992)
J Biol Chem
, vol.267
, pp. 23797-23805
-
-
Butler, J.D.1
Banchette-Mackie, J.2
Golden, E.3
-
120
-
-
0031013536
-
Role of multidrug resistance P-glycoproteins in cholesterol esterification
-
Debry P, Nash EA, Neklason DW, Metherall JE. Role of multidrug resistance P-glycoproteins in cholesterol esterification. J Biol Chem 1997; 272: 1026-1031.
-
(1997)
J Biol Chem
, vol.272
, pp. 1026-1031
-
-
Debry, P.1
Nash, E.A.2
Neklason, D.W.3
Metherall, J.E.4
-
121
-
-
0038433334
-
Effects of troglitazone on intracellular cholesterol distribution and cholesterol-dependent cell functions in MA-10 Leydig tumor cells
-
Freeman DA, Romero A. Effects of troglitazone on intracellular cholesterol distribution and cholesterol-dependent cell functions in MA-10 Leydig tumor cells. Biochem Pharmacol 2003; 66: 307-313.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 307-313
-
-
Freeman, D.A.1
Romero, A.2
-
122
-
-
71849099881
-
Amyloid beta and APP as biomarkers for. Alzheimer's disease
-
Zetterberg H, Blennow K, Hanse E. Amyloid beta and APP as biomarkers for. Alzheimer's disease. Exp Gerontol 2010; 45: 23-29.
-
(2010)
Exp Gerontol
, vol.45
, pp. 23-29
-
-
Zetterberg, H.1
Blennow, K.2
Hanse, E.3
-
123
-
-
2542502430
-
ApoE genotype accounts for the vast majority of AD risk and AD pathology
-
Raber J, Huang Y, Ashford JW. ApoE genotype accounts for the vast majority of AD risk and AD pathology. Neurobiol Aging 2004; 25: 641-650.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 641-650
-
-
Raber, J.1
Huang, Y.2
Ashford, J.W.3
-
124
-
-
47049119998
-
Biomarkers for cognitive impairment and dementia in elderly people
-
Sonnen JA, Montin KS, Quinn JF, et al. Biomarkers for cognitive impairment and dementia in elderly people. Lancet Neurol 2008; 7: 704-714.
-
(2008)
Lancet Neurol
, vol.7
, pp. 704-714
-
-
Sonnen, J.A.1
Montin, K.S.2
Quinn, J.F.3
-
125
-
-
8344278010
-
Acyl coenzyme A:Cholesterol acyltransferase inhibitors as hypolipidemic and antiatherosclerotic drugs
-
Alegret M, Llaverias G, Silvestre JS. Acyl coenzyme A:cholesterol acyltransferase inhibitors as hypolipidemic and antiatherosclerotic drugs. Methods Find Exp Clin Pharmacol 2004; 26: 563-586.
-
(2004)
Methods Find Exp Clin Pharmacol
, vol.26
, pp. 563-586
-
-
Alegret, M.1
Llaverias, G.2
Silvestre, J.S.3
-
126
-
-
44049085833
-
A multimeric quinacrine conjugate as a potential inhibitor of Alzheimer's β-amyloid fibril formation
-
Dolphin GT, Chierici S, Ouberai M, Dumy P, Garcia J. A multimeric quinacrine conjugate as a potential inhibitor of Alzheimer's β-amyloid fibril formation. ChemBioChem 2008; 9: 952-963.
-
(2008)
ChemBioChem
, vol.9
, pp. 952-963
-
-
Dolphin, G.T.1
Chierici, S.2
Ouberai, M.3
Dumy, P.4
Garcia, J.5
-
127
-
-
77957952943
-
-
CJD (Creutzfeldt-Jakob disease) quinacrine study. Available at:, [accessed March 4, 2009]
-
CJD (Creutzfeldt-Jakob disease) quinacrine study. Available at: http://clinicaltrials.gov/ct2/show/NCT00183092 [accessed March 4, 2009].
-
-
-
-
128
-
-
79959479102
-
Efficacy of PPAR-gamma agonist pioglitazone in mild Alzheimer disease
-
Nov 16 [Epub Ahead of Print] Doi:10.1016/jneurobiolaging
-
Sato T, Hanyu H, Hirao K, et al. Efficacy of PPAR-gamma agonist pioglitazone in mild Alzheimer disease. Neurobiol Aging 2009; Nov 16 [Epub ahead of print] Doi:10.1016/jneurobiolaging. 2009.10.009.
-
(2009)
Neurobiol Aging
-
-
Sato, T.1
Hanyu, H.2
Hirao, K.3
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