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Volumn 7, Issue , 2006, Pages

Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs

Author keywords

[No Author keywords available]

Indexed keywords

7 DEHYDROCHOLESTEROL; ACETYL COENZYME A ACETYLTRANSFERASE; ACYL COENZYME A DESATURASE; CHLORPROMAZINE; CLOZAPINE; FATTY ACID SYNTHASE; GERANYLTRANSFERASE; HALOPERIDOL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; LOW DENSITY LIPOPROTEIN RECEPTOR; NEUROLEPTIC AGENT; OLANZAPINE; RISPERIDONE; STEROL REGULATORY ELEMENT BINDING PROTEIN; ZIPRASIDONE;

EID: 33750980390     PISSN: 14712202     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-7-69     Document Type: Article
Times cited : (80)

References (42)
  • 6
    • 3543104951 scopus 로고    scopus 로고
    • Thematic review series: Brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal
    • Dietschy JM, Turley SD: Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal. J Lipid Res 2004, 45:1375-1397.
    • (2004) J Lipid Res , vol.45 , pp. 1375-1397
    • Dietschy, J.M.1    Turley, S.D.2
  • 8
    • 0141455897 scopus 로고    scopus 로고
    • Understanding antipsychotic "atypicality": A clinical and pharmacological moving target
    • Remington G: Understanding antipsychotic "atypicality": a clinical and pharmacological moving target. J Psychiatry Neurosci 2003, 28:275-284.
    • (2003) J Psychiatry Neurosci , vol.28 , pp. 275-284
    • Remington, G.1
  • 9
    • 0038653525 scopus 로고    scopus 로고
    • A meta-analysis of the efficacy of second-generation antipsychotics
    • Davis JM, Chen N, Glick ID: A meta-analysis of the efficacy of second-generation antipsychotics. Arch Gen Psychiatry 2003, 60:553-564.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 553-564
    • Davis, J.M.1    Chen, N.2    Glick, I.D.3
  • 10
    • 0033983417 scopus 로고    scopus 로고
    • Atypical antipsychotics: Are some more atypical than others?
    • Remington G, Kapur S: Atypical antipsychotics: are some more atypical than others? Psychopharmacology (Berl) 2000, 148:3-15.
    • (2000) Psychopharmacology (Berl) , vol.148 , pp. 3-15
    • Remington, G.1    Kapur, S.2
  • 13
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, Brown MS: SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002, 109:1125-1131.
    • (2002) J Clin Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 15
    • 0030907175 scopus 로고    scopus 로고
    • Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
    • Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL: Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 1997, 99:846-854.
    • (1997) J Clin Invest , vol.99 , pp. 846-854
    • Shimano, H.1    Horton, J.D.2    Shimomura, I.3    Hammer, R.E.4    Brown, M.S.5    Goldstein, J.L.6
  • 16
    • 0030961960 scopus 로고    scopus 로고
    • Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
    • Shimomura I, Shimano H, Horton JD, Goldstein JL, Brown MS: Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J Clin Invest 1997, 99:838-845.
    • (1997) J Clin Invest , vol.99 , pp. 838-845
    • Shimomura, I.1    Shimano, H.2    Horton, J.D.3    Goldstein, J.L.4    Brown, M.S.5
  • 17
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL: Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest 1996, 98:1575-1584.
    • (1996) J Clin Invest , vol.98 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 18
    • 0032568557 scopus 로고    scopus 로고
    • Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
    • Horton JD, Bashmakov Y, Shimomura I, Shimano H: Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc Natl Acad Sci U S A 1998, 95:5987-5992.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5987-5992
    • Horton, J.D.1    Bashmakov, Y.2    Shimomura, I.3    Shimano, H.4
  • 19
    • 0035976936 scopus 로고    scopus 로고
    • The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols
    • Janowski BA, Shan B, Russell DW: The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols. J Biol Chem 2001, 276:45408-45416.
    • (2001) J Biol Chem , vol.276 , pp. 45408-45416
    • Janowski, B.A.1    Shan, B.2    Russell, D.W.3
  • 20
    • 0033384957 scopus 로고    scopus 로고
    • Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol
    • Lange Y, Ye J, Rigney M, Steck TL: Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol. J Lipid Res 1999, 40:2264-2270.
    • (1999) J Lipid Res , vol.40 , pp. 2264-2270
    • Lange, Y.1    Ye, J.2    Rigney, M.3    Steck, T.L.4
  • 22
    • 12344326514 scopus 로고    scopus 로고
    • Treatments for schizophrenia: A critical review of pharmacology and mechanisms of action of antipsychotic drugs
    • Miyamoto S, Duncan GE, Marx CE, Lieberman JA: Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry 2005, 10:79-104.
    • (2005) Mol Psychiatry , vol.10 , pp. 79-104
    • Miyamoto, S.1    Duncan, G.E.2    Marx, C.E.3    Lieberman, J.A.4
  • 23
    • 32244431947 scopus 로고    scopus 로고
    • Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells
    • Raeder MB, Ferno J, Glambek M, Stansberg C, Steen VM: Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. Neurosci Lett 2006, 395:185-190.
    • (2006) Neurosci Lett , vol.395 , pp. 185-190
    • Raeder, M.B.1    Ferno, J.2    Glambek, M.3    Stansberg, C.4    Steen, V.M.5
  • 24
    • 0027972084 scopus 로고
    • Cholesterol homeostasis. Modulation by amphiphiles
    • Lange Y, Steck TL: Cholesterol homeostasis. Modulation by amphiphiles. J Biol Chem 1994, 269:29371-29374.
    • (1994) J Biol Chem , vol.269 , pp. 29371-29374
    • Lange, Y.1    Steck, T.L.2
  • 25
    • 0033613126 scopus 로고    scopus 로고
    • Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi
    • Nohturfft A, DeBose-Boyd RA, Scheek S, Goldstein JL, Brown MS: Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi. Proc Natl Acad Sci U S A 1999, 96:11235-11240.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 11235-11240
    • Nohturfft, A.1    DeBose-Boyd, R.A.2    Scheek, S.3    Goldstein, J.L.4    Brown, M.S.5
  • 26
    • 10644239801 scopus 로고    scopus 로고
    • Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs
    • Adams CM, Reitz J, De Brabander JK, Feramisco JD, Li L, Brown MS, Goldstein JL: Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs. J Biol Chem 2004, 279:52772-52780.
    • (2004) J Biol Chem , vol.279 , pp. 52772-52780
    • Adams, C.M.1    Reitz, J.2    De Brabander, J.K.3    Feramisco, J.D.4    Li, L.5    Brown, M.S.6    Goldstein, J.L.7
  • 27
    • 0141591549 scopus 로고    scopus 로고
    • Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles
    • Adams CM, Goldstein JL, Brown MS: Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles. Proc Natl Acad Sci U S A 2003, 100:10647-10652.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10647-10652
    • Adams, C.M.1    Goldstein, J.L.2    Brown, M.S.3
  • 29
    • 0028212507 scopus 로고
    • Developmental regulation of the expression of genes encoding proteins involved in cholesterol homeostasis
    • Ness GC: Developmental regulation of the expression of genes encoding proteins involved in cholesterol homeostasis. Am J Med Genet 1994, 50:355-357.
    • (1994) Am J Med Genet , vol.50 , pp. 355-357
    • Ness, G.C.1
  • 30
    • 0033985644 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
    • Glantz LA, Lewis DA: Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry 2000, 57:65-73.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 65-73
    • Glantz, L.A.1    Lewis, D.A.2
  • 31
    • 0032950768 scopus 로고    scopus 로고
    • Synaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illness
    • Honer WG, Falkai P, Chen C, Arango V, Mann JJ, Dwork AJ: Synaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illness. Neuroscience 1999, 91:1247-1255.
    • (1999) Neuroscience , vol.91 , pp. 1247-1255
    • Honer, W.G.1    Falkai, P.2    Chen, C.3    Arango, V.4    Mann, J.J.5    Dwork, A.J.6
  • 32
    • 0030923288 scopus 로고    scopus 로고
    • Development of the prefrontal cortex during adolescence: Insights into vulnerable neural circuits in schizophrenia
    • Lewis DA: Development of the prefrontal cortex during adolescence: insights into vulnerable neural circuits in schizophrenia. Neuropsychopharmacology 1997, 16:385-398.
    • (1997) Neuropsychopharmacology , vol.16 , pp. 385-398
    • Lewis, D.A.1
  • 33
    • 0035426751 scopus 로고    scopus 로고
    • Analysis of complex brain disorders with gene expression microarrays: Schizophrenia as a disease of the synapse
    • Mirnics K, Middleton FA, Lewis DA, Levitt P: Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends Neurosci 2001, 24:479-486.
    • (2001) Trends Neurosci , vol.24 , pp. 479-486
    • Mirnics, K.1    Middleton, F.A.2    Lewis, D.A.3    Levitt, P.4
  • 34
    • 19444372396 scopus 로고    scopus 로고
    • Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron
    • Goritz C, Mauch DH, Pfrieger FW: Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron. Mol Cell Neurosci 2005, 29:190-201.
    • (2005) Mol Cell Neurosci , vol.29 , pp. 190-201
    • Goritz, C.1    Mauch, D.H.2    Pfrieger, F.W.3
  • 35
    • 0037230328 scopus 로고    scopus 로고
    • Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes?
    • Pfrieger FW: Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? Bioessays 2003, 25:72-78.
    • (2003) Bioessays , vol.25 , pp. 72-78
    • Pfrieger, F.W.1
  • 39
    • 0031746826 scopus 로고    scopus 로고
    • Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome
    • Buchanan RW, Breier A, Kirkpatrick B, Ball P, Carpenter WTJ: Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome. Am J Psychiatry 1998, 155:751-760.
    • (1998) Am J Psychiatry , vol.155 , pp. 751-760
    • Buchanan, R.W.1    Breier, A.2    Kirkpatrick, B.3    Ball, P.4    Carpenter, W.T.J.5
  • 40
    • 0142244688 scopus 로고    scopus 로고
    • Schizophrenia
    • Freedman R: Schizophrenia. N Engl J Med 2003, 349:1738-1749.
    • (2003) N Engl J Med , vol.349 , pp. 1738-1749
    • Freedman, R.1
  • 41
    • 0023737022 scopus 로고
    • Characteristics of human and rat glioma cells grown in a defined medium
    • Akslen LA, Andersen KJ, Bjerkvig R: Characteristics of human and rat glioma cells grown in a defined medium. Anticancer Res 1988, 8:797-803.
    • (1988) Anticancer Res , vol.8 , pp. 797-803
    • Akslen, L.A.1    Andersen, K.J.2    Bjerkvig, R.3
  • 42
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • Winer J, Jung CK, Shackel I, Williams PM: Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 1999, 270:41-49.
    • (1999) Anal Biochem , vol.270 , pp. 41-49
    • Winer, J.1    Jung, C.K.2    Shackel, I.3    Williams, P.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.