-
1
-
-
0035836642
-
Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
-
Hakak Y, Walker JR, Li C, Wong WH, Davis KL, Buxbaum JD, Haroutunian V, Fienberg AA: Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc Natl Acad Sci U S A 2001, 98:4746-4751.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4746-4751
-
-
Hakak, Y.1
Walker, J.R.2
Li, C.3
Wong, W.H.4
Davis, K.L.5
Buxbaum, J.D.6
Haroutunian, V.7
Fienberg, A.A.8
-
2
-
-
0037839787
-
Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia
-
Hof PR, Haroutunian V, Friedrich VLJ, Byne W, Buitron C, Perl DP, Davis KL: Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia. Biol Psychiatry 2003, 53:1075-1085.
-
(2003)
Biol Psychiatry
, vol.53
, pp. 1075-1085
-
-
Hof, P.R.1
Haroutunian, V.2
Friedrich, V.L.J.3
Byne, W.4
Buitron, C.5
Perl, D.P.6
Davis, K.L.7
-
3
-
-
0038643584
-
White matter changes in schizophrenia: Evidence for myelin-related dysfunction
-
Davis KL, Stewart DG, Friedman JI, Buchsbaum M, Harvey PD, Hof PR, Buxbaum J, Haroutunian V: White matter changes in schizophrenia: evidence for myelin-related dysfunction. Arch Gen Psychiatry 2003, 60:443-456.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 443-456
-
-
Davis, K.L.1
Stewart, D.G.2
Friedman, J.I.3
Buchsbaum, M.4
Harvey, P.D.5
Hof, P.R.6
Buxbaum, J.7
Haroutunian, V.8
-
4
-
-
0041328892
-
Oligodendrocyte dysfunction in schizophrenia and bipolar disorder
-
Tkachev D, Mimmack ML, Ryan MM, Wayland M, Freeman T, Jones PB, Starkey M, Webster MJ, Yolken RH, Bahn S: Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 2003, 362:798-805.
-
(2003)
Lancet
, vol.362
, pp. 798-805
-
-
Tkachev, D.1
Mimmack, M.L.2
Ryan, M.M.3
Wayland, M.4
Freeman, T.5
Jones, P.B.6
Starkey, M.7
Webster, M.J.8
Yolken, R.H.9
Bahn, S.10
-
5
-
-
0035878141
-
Electron microscopy of oligodendroglia in severe mental illness
-
Uranova N, Orlovskaya D, Vikhreva O, Zimina I, Kolomeets N, Vostrikov V, Rachmanova V: Electron microscopy of oligodendroglia in severe mental illness. Brain Res Bull 2001, 55:597-610.
-
(2001)
Brain Res Bull
, vol.55
, pp. 597-610
-
-
Uranova, N.1
Orlovskaya, D.2
Vikhreva, O.3
Zimina, I.4
Kolomeets, N.5
Vostrikov, V.6
Rachmanova, V.7
-
6
-
-
3543104951
-
Thematic review series: Brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal
-
Dietschy JM, Turley SD: Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal. J Lipid Res 2004, 45:1375-1397.
-
(2004)
J Lipid Res
, vol.45
, pp. 1375-1397
-
-
Dietschy, J.M.1
Turley, S.D.2
-
7
-
-
0035834416
-
CNS synaptogenesis promoted by glia-derived cholesterol
-
Mauch DH, Nagler K, Schumacher S, Goritz C, Muller EC, Otto A, Pfrieger FW: CNS synaptogenesis promoted by glia-derived cholesterol. Science 2001, 294:1354-1357.
-
(2001)
Science
, vol.294
, pp. 1354-1357
-
-
Mauch, D.H.1
Nagler, K.2
Schumacher, S.3
Goritz, C.4
Muller, E.C.5
Otto, A.6
Pfrieger, F.W.7
-
8
-
-
0141455897
-
Understanding antipsychotic "atypicality": A clinical and pharmacological moving target
-
Remington G: Understanding antipsychotic "atypicality": a clinical and pharmacological moving target. J Psychiatry Neurosci 2003, 28:275-284.
-
(2003)
J Psychiatry Neurosci
, vol.28
, pp. 275-284
-
-
Remington, G.1
-
9
-
-
0038653525
-
A meta-analysis of the efficacy of second-generation antipsychotics
-
Davis JM, Chen N, Glick ID: A meta-analysis of the efficacy of second-generation antipsychotics. Arch Gen Psychiatry 2003, 60:553-564.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 553-564
-
-
Davis, J.M.1
Chen, N.2
Glick, I.D.3
-
10
-
-
0033983417
-
Atypical antipsychotics: Are some more atypical than others?
-
Remington G, Kapur S: Atypical antipsychotics: are some more atypical than others? Psychopharmacology (Berl) 2000, 148:3-15.
-
(2000)
Psychopharmacology (Berl)
, vol.148
, pp. 3-15
-
-
Remington, G.1
Kapur, S.2
-
11
-
-
0032751075
-
Antipsychotic-induced weight gain: A comprehensive research synthesis
-
Allison DB, Mentore JL, Heo M, Chandler LP, Cappelleri JC, Infante MC, Weiden PJ: Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry 1999, 156:1686-1696.
-
(1999)
Am J Psychiatry
, vol.156
, pp. 1686-1696
-
-
Allison, D.B.1
Mentore, J.L.2
Heo, M.3
Chandler, L.P.4
Cappelleri, J.C.5
Infante, M.C.6
Weiden, P.J.7
-
12
-
-
27144450193
-
Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: A novel mechanism of action?
-
Ferno J, Raeder MB, Vik-Mo AO, Skrede S, Glambek M, Tronstad KJ, Breilid H, Lovlie R, Berge RK, Stansberg C, Steen VM: Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? Pharmacogenomics J 2005, 5:298-304.
-
(2005)
Pharmacogenomics J
, vol.5
, pp. 298-304
-
-
Ferno, J.1
Raeder, M.B.2
Vik-Mo, A.O.3
Skrede, S.4
Glambek, M.5
Tronstad, K.J.6
Breilid, H.7
Lovlie, R.8
Berge, R.K.9
Stansberg, C.10
Steen, V.M.11
-
13
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton JD, Goldstein JL, Brown MS: SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002, 109:1125-1131.
-
(2002)
J Clin Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
14
-
-
0142027805
-
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
-
Horton JD, Shah NA, Warrington JA, Anderson NN, Park SW, Brown MS, Goldstein JL: Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes. Proc Natl Acad Sci U S A 2003, 100:12027-12032.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12027-12032
-
-
Horton, J.D.1
Shah, N.A.2
Warrington, J.A.3
Anderson, N.N.4
Park, S.W.5
Brown, M.S.6
Goldstein, J.L.7
-
15
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
-
Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL: Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 1997, 99:846-854.
-
(1997)
J Clin Invest
, vol.99
, pp. 846-854
-
-
Shimano, H.1
Horton, J.D.2
Shimomura, I.3
Hammer, R.E.4
Brown, M.S.5
Goldstein, J.L.6
-
16
-
-
0030961960
-
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
-
Shimomura I, Shimano H, Horton JD, Goldstein JL, Brown MS: Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J Clin Invest 1997, 99:838-845.
-
(1997)
J Clin Invest
, vol.99
, pp. 838-845
-
-
Shimomura, I.1
Shimano, H.2
Horton, J.D.3
Goldstein, J.L.4
Brown, M.S.5
-
17
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
-
Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL: Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest 1996, 98:1575-1584.
-
(1996)
J Clin Invest
, vol.98
, pp. 1575-1584
-
-
Shimano, H.1
Horton, J.D.2
Hammer, R.E.3
Shimomura, I.4
Brown, M.S.5
Goldstein, J.L.6
-
18
-
-
0032568557
-
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
-
Horton JD, Bashmakov Y, Shimomura I, Shimano H: Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc Natl Acad Sci U S A 1998, 95:5987-5992.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5987-5992
-
-
Horton, J.D.1
Bashmakov, Y.2
Shimomura, I.3
Shimano, H.4
-
19
-
-
0035976936
-
The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols
-
Janowski BA, Shan B, Russell DW: The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols. J Biol Chem 2001, 276:45408-45416.
-
(2001)
J Biol Chem
, vol.276
, pp. 45408-45416
-
-
Janowski, B.A.1
Shan, B.2
Russell, D.W.3
-
20
-
-
0033384957
-
Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol
-
Lange Y, Ye J, Rigney M, Steck TL: Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol. J Lipid Res 1999, 40:2264-2270.
-
(1999)
J Lipid Res
, vol.40
, pp. 2264-2270
-
-
Lange, Y.1
Ye, J.2
Rigney, M.3
Steck, T.L.4
-
21
-
-
0038014053
-
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs
-
Kroeze WK, Hufeisen SJ, Popadak BA, Renock SM, Steinberg S, Ernsberger P, Jayathilake K, Meltzer HY, Roth BL: H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology 2003, 28:519-526.
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 519-526
-
-
Kroeze, W.K.1
Hufeisen, S.J.2
Popadak, B.A.3
Renock, S.M.4
Steinberg, S.5
Ernsberger, P.6
Jayathilake, K.7
Meltzer, H.Y.8
Roth, B.L.9
-
22
-
-
12344326514
-
Treatments for schizophrenia: A critical review of pharmacology and mechanisms of action of antipsychotic drugs
-
Miyamoto S, Duncan GE, Marx CE, Lieberman JA: Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry 2005, 10:79-104.
-
(2005)
Mol Psychiatry
, vol.10
, pp. 79-104
-
-
Miyamoto, S.1
Duncan, G.E.2
Marx, C.E.3
Lieberman, J.A.4
-
23
-
-
32244431947
-
Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells
-
Raeder MB, Ferno J, Glambek M, Stansberg C, Steen VM: Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. Neurosci Lett 2006, 395:185-190.
-
(2006)
Neurosci Lett
, vol.395
, pp. 185-190
-
-
Raeder, M.B.1
Ferno, J.2
Glambek, M.3
Stansberg, C.4
Steen, V.M.5
-
24
-
-
0027972084
-
Cholesterol homeostasis. Modulation by amphiphiles
-
Lange Y, Steck TL: Cholesterol homeostasis. Modulation by amphiphiles. J Biol Chem 1994, 269:29371-29374.
-
(1994)
J Biol Chem
, vol.269
, pp. 29371-29374
-
-
Lange, Y.1
Steck, T.L.2
-
25
-
-
0033613126
-
Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi
-
Nohturfft A, DeBose-Boyd RA, Scheek S, Goldstein JL, Brown MS: Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi. Proc Natl Acad Sci U S A 1999, 96:11235-11240.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11235-11240
-
-
Nohturfft, A.1
DeBose-Boyd, R.A.2
Scheek, S.3
Goldstein, J.L.4
Brown, M.S.5
-
26
-
-
10644239801
-
Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs
-
Adams CM, Reitz J, De Brabander JK, Feramisco JD, Li L, Brown MS, Goldstein JL: Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs. J Biol Chem 2004, 279:52772-52780.
-
(2004)
J Biol Chem
, vol.279
, pp. 52772-52780
-
-
Adams, C.M.1
Reitz, J.2
De Brabander, J.K.3
Feramisco, J.D.4
Li, L.5
Brown, M.S.6
Goldstein, J.L.7
-
27
-
-
0141591549
-
Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles
-
Adams CM, Goldstein JL, Brown MS: Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles. Proc Natl Acad Sci U S A 2003, 100:10647-10652.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10647-10652
-
-
Adams, C.M.1
Goldstein, J.L.2
Brown, M.S.3
-
28
-
-
20044370505
-
High cholesterol level is essential for myelin membrane growth
-
Saher G, Brugger B, Lappe-Siefke C, Mobius W, Tozawa R, Wehr MC, Wieland F, Ishibashi S, Nave KA: High cholesterol level is essential for myelin membrane growth. Nat Neurosci 2005, 8:468-475.
-
(2005)
Nat Neurosci
, vol.8
, pp. 468-475
-
-
Saher, G.1
Brugger, B.2
Lappe-Siefke, C.3
Mobius, W.4
Tozawa, R.5
Wehr, M.C.6
Wieland, F.7
Ishibashi, S.8
Nave, K.A.9
-
29
-
-
0028212507
-
Developmental regulation of the expression of genes encoding proteins involved in cholesterol homeostasis
-
Ness GC: Developmental regulation of the expression of genes encoding proteins involved in cholesterol homeostasis. Am J Med Genet 1994, 50:355-357.
-
(1994)
Am J Med Genet
, vol.50
, pp. 355-357
-
-
Ness, G.C.1
-
30
-
-
0033985644
-
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
-
Glantz LA, Lewis DA: Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry 2000, 57:65-73.
-
(2000)
Arch Gen Psychiatry
, vol.57
, pp. 65-73
-
-
Glantz, L.A.1
Lewis, D.A.2
-
31
-
-
0032950768
-
Synaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illness
-
Honer WG, Falkai P, Chen C, Arango V, Mann JJ, Dwork AJ: Synaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illness. Neuroscience 1999, 91:1247-1255.
-
(1999)
Neuroscience
, vol.91
, pp. 1247-1255
-
-
Honer, W.G.1
Falkai, P.2
Chen, C.3
Arango, V.4
Mann, J.J.5
Dwork, A.J.6
-
32
-
-
0030923288
-
Development of the prefrontal cortex during adolescence: Insights into vulnerable neural circuits in schizophrenia
-
Lewis DA: Development of the prefrontal cortex during adolescence: insights into vulnerable neural circuits in schizophrenia. Neuropsychopharmacology 1997, 16:385-398.
-
(1997)
Neuropsychopharmacology
, vol.16
, pp. 385-398
-
-
Lewis, D.A.1
-
33
-
-
0035426751
-
Analysis of complex brain disorders with gene expression microarrays: Schizophrenia as a disease of the synapse
-
Mirnics K, Middleton FA, Lewis DA, Levitt P: Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends Neurosci 2001, 24:479-486.
-
(2001)
Trends Neurosci
, vol.24
, pp. 479-486
-
-
Mirnics, K.1
Middleton, F.A.2
Lewis, D.A.3
Levitt, P.4
-
34
-
-
19444372396
-
Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron
-
Goritz C, Mauch DH, Pfrieger FW: Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron. Mol Cell Neurosci 2005, 29:190-201.
-
(2005)
Mol Cell Neurosci
, vol.29
, pp. 190-201
-
-
Goritz, C.1
Mauch, D.H.2
Pfrieger, F.W.3
-
35
-
-
0037230328
-
Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes?
-
Pfrieger FW: Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? Bioessays 2003, 25:72-78.
-
(2003)
Bioessays
, vol.25
, pp. 72-78
-
-
Pfrieger, F.W.1
-
36
-
-
9744251578
-
The AGNP-TDM expert group consensus guidelines: Therapeutic drug monitoring in psychiatry
-
Baumann P, Hiemke C, Ulrich S, Eckermann G, Gaertner I, Gerlach M, Kuss HJ, Laux G, Muller-Oerlinghausen B, Rao ML, Riederer P, Zernig G: The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in psychiatry. Pharmacopsychiatry 2004, 37:243-265.
-
(2004)
Pharmacopsychiatry
, vol.37
, pp. 243-265
-
-
Baumann, P.1
Hiemke, C.2
Ulrich, S.3
Eckermann, G.4
Gaertner, I.5
Gerlach, M.6
Kuss, H.J.7
Laux, G.8
Muller-Oerlinghausen, B.9
Rao, M.L.10
Riederer, P.11
Zernig, G.12
-
37
-
-
0033009682
-
Persistence of haloperidol in human brain tissue
-
Kornhuber J, Schultz A, Wiltfang J, Meineke I, Gleiter CH, Zochling R, Boissl KW, Leblhuber F, Riederer P: Persistence of haloperidol in human brain tissue. Am J Psychiatry 1999, 156:885-890.
-
(1999)
Am J Psychiatry
, vol.156
, pp. 885-890
-
-
Kornhuber, J.1
Schultz, A.2
Wiltfang, J.3
Meineke, I.4
Gleiter, C.H.5
Zochling, R.6
Boissl, K.W.7
Leblhuber, F.8
Riederer, P.9
-
38
-
-
0344141457
-
Distribution of clozapine and desmethylclozapine between blood and brain in rats
-
Weigmann H, Hartter S, Fischer V, Dahmen N, Hiemke C: Distribution of clozapine and desmethylclozapine between blood and brain in rats. Eur Neuropsychopharmacol 1999, 9:253-256.
-
(1999)
Eur Neuropsychopharmacol
, vol.9
, pp. 253-256
-
-
Weigmann, H.1
Hartter, S.2
Fischer, V.3
Dahmen, N.4
Hiemke, C.5
-
39
-
-
0031746826
-
Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome
-
Buchanan RW, Breier A, Kirkpatrick B, Ball P, Carpenter WTJ: Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome. Am J Psychiatry 1998, 155:751-760.
-
(1998)
Am J Psychiatry
, vol.155
, pp. 751-760
-
-
Buchanan, R.W.1
Breier, A.2
Kirkpatrick, B.3
Ball, P.4
Carpenter, W.T.J.5
-
40
-
-
0142244688
-
Schizophrenia
-
Freedman R: Schizophrenia. N Engl J Med 2003, 349:1738-1749.
-
(2003)
N Engl J Med
, vol.349
, pp. 1738-1749
-
-
Freedman, R.1
-
41
-
-
0023737022
-
Characteristics of human and rat glioma cells grown in a defined medium
-
Akslen LA, Andersen KJ, Bjerkvig R: Characteristics of human and rat glioma cells grown in a defined medium. Anticancer Res 1988, 8:797-803.
-
(1988)
Anticancer Res
, vol.8
, pp. 797-803
-
-
Akslen, L.A.1
Andersen, K.J.2
Bjerkvig, R.3
-
42
-
-
0033562350
-
Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
-
Winer J, Jung CK, Shackel I, Williams PM: Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 1999, 270:41-49.
-
(1999)
Anal Biochem
, vol.270
, pp. 41-49
-
-
Winer, J.1
Jung, C.K.2
Shackel, I.3
Williams, P.M.4
|