메뉴 건너뛰기




Volumn 185, Issue 3, 2010, Pages 1920-1926

Altered effector CD4+ T cell function in IL-21R-/- CD4+ T cell-mediated graft-versus-host disease

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; AUTACOID; IL21R PROTEIN, MOUSE; INTERLEUKIN 21 RECEPTOR ALPHA; INTERLEUKIN DERIVATIVE;

EID: 77956408137     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902217     Document Type: Article
Times cited : (16)

References (43)
  • 2
    • 42649134105 scopus 로고    scopus 로고
    • Interleukin-21: Basic biology and implications for cancer and autoimmunity
    • Spolski, R., and W. J. Leonard. 2008. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 26: 57-79.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 57-79
    • Spolski, R.1    Leonard, W.J.2
  • 3
    • 0034633734 scopus 로고    scopus 로고
    • Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain
    • Ozaki, K., K. Kikly, D. Michalovich, P. R. Young, and W. J. Leonard. 2000. Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain. Proc. Natl. Acad. Sci. USA 97: 11439-11444.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11439-11444
    • Ozaki, K.1    Kikly, K.2    Michalovich, D.3    Young, P.R.4    Leonard, W.J.5
  • 4
    • 0345257344 scopus 로고    scopus 로고
    • Interleukin-21 inhibits dendritic cell activation and maturation
    • DOI 10.1182/blood-2003-03-0669
    • Brandt, K., S. Bulfone-Paus, D. C. Foster, and R. Rückert. 2003. Interleukin-21 inhibits dendritic cell activation and maturation. Blood 102: 4090-4098. (Pubitemid 37486993)
    • (2003) Blood , vol.102 , Issue.12 , pp. 4090-4098
    • Brandt, K.1    Bulfone-Paus, S.2    Foster, D.C.3    Ruckert, R.4
  • 10
    • 0037037544 scopus 로고    scopus 로고
    • Interleukin 21 is at helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells
    • Wurster, A. L., V. L. Rodgers, A. R. Satoskar, M. J. Whitters, D. A. Young, M. Collins, and M. J. Grusby. 2002. Interleukin 21 is aT helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells. J. Exp. Med. 196: 969-977.
    • (2002) J. Exp. Med. , vol.196 , pp. 969-977
    • Wurster, A.L.1    Rodgers, V.L.2    Satoskar, A.R.3    Whitters, M.J.4    Young, D.A.5    Collins, M.6    Grusby, M.J.7
  • 12
    • 33847412873 scopus 로고    scopus 로고
    • IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo
    • DOI 10.1182/blood-2006-05-021600
    • Fröhlich, A., B. J. Marsland, I. Sonderegger, M. Kurrer, M. R. Hodge, N. L. Harris, and M. Kopf. 2007. IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood 109: 2023-2031. (Pubitemid 46348202)
    • (2007) Blood , vol.109 , Issue.5 , pp. 2023-2031
    • Frohlich, A.1    Marsland, B.J.2    Sonderegger, I.3    Kurrer, M.4    Hodge, M.R.5    Harris, N.L.6    Kopf, M.7
  • 13
    • 0036784616 scopus 로고    scopus 로고
    • IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response
    • Strengell, M., T. Sareneva, D. Foster, I. Julkunen, and S. Matikainen. 2002. IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response. J. Immunol. 169: 3600-3605.
    • (2002) J. Immunol. , vol.169 , pp. 3600-3605
    • Strengell, M.1    Sareneva, T.2    Foster, D.3    Julkunen, I.4    Matikainen, S.5
  • 14
    • 46749156754 scopus 로고    scopus 로고
    • Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis
    • Coquet, J. M., S. Chakravarti, M. J. Smyth, and D. I. Godfrey. 2008. Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis. J. Immunol. 180: 7097-7101.
    • (2008) J. Immunol. , vol.180 , pp. 7097-7101
    • Coquet, J.M.1    Chakravarti, S.2    Smyth, M.J.3    Godfrey, D.I.4
  • 15
    • 46749133961 scopus 로고    scopus 로고
    • IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo
    • Sonderegger, I., J. Kisielow, R. Meier, C. King, and M. Kopf. 2008. IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo. Eur. J. Immunol. 38: 1833-1838.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 1833-1838
    • Sonderegger, I.1    Kisielow, J.2    Meier, R.3    King, C.4    Kopf, M.5
  • 18
    • 1942453326 scopus 로고    scopus 로고
    • Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
    • DOI 10.1016/S0092-8674(04)00335-6, PII S0092867404003356
    • King, C., A. Ilic, K. Koelsch, and N. Sarvetnick. 2004. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 117: 265-277. (Pubitemid 38496245)
    • (2004) Cell , vol.117 , Issue.2 , pp. 265-277
    • King, C.1    Ilic, A.2    Koelsch, K.3    Sarvetnick, N.4
  • 19
    • 52949091915 scopus 로고    scopus 로고
    • IL-21 signaling is critical for the development of type I diabetes in the NOD mouse
    • Spolski, R., M. Kashyap, C. Robinson, Z. Yu, and W. J. Leonard. 2008. IL-21 signaling is critical for the development of type I diabetes in the NOD mouse. Proc. Natl. Acad. Sci. USA 105: 14028-14033.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 14028-14033
    • Spolski, R.1    Kashyap, M.2    Robinson, C.3    Yu, Z.4    Leonard, W.J.5
  • 21
    • 34247573902 scopus 로고    scopus 로고
    • Graft-versus-host disease
    • Shlomchik, W. D. 2007. Graft-versus-host disease. Nat. Rev. Immunol. 7: 340-352.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 340-352
    • Shlomchik, W.D.1
  • 23
    • 0036754255 scopus 로고    scopus 로고
    • Antigen-specific T cell sensitization is impaired in Il-17-deficient mice, causing suppression of allergic cellular and humoral responses
    • DOI 10.1016/S1074-7613(02)00391-6
    • Nakae, S., Y. Komiyama, A. Nambu, K. Sudo, M. Iwase, I. Homma, K. Sekikawa, M. Asano, and Y. Iwakura. 2002. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 17: 375-387. (Pubitemid 35279557)
    • (2002) Immunity , vol.17 , Issue.3 , pp. 375-387
    • Nakae, S.1    Komiyama, Y.2    Nambu, A.3    Sudo, K.4    Iwase, M.5    Homma, I.6    Sekikawa, K.7    Asano, M.8    Iwakura, Y.9
  • 24
    • 33846910425 scopus 로고    scopus 로고
    • Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease
    • DOI 10.1182/blood-2006-08-042853
    • Sakoda, Y., D. Hashimoto, S. Asakura, K. Takeuchi, M. Harada, M. Tanimoto, and T. Teshima. 2007. Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease. Blood 109: 1756-1764. (Pubitemid 46239612)
    • (2007) Blood , vol.109 , Issue.4 , pp. 1756-1764
    • Sakoda, Y.1    Hashimoto, D.2    Asakura, S.3    Takeuchi, K.4    Harada, M.5    Tanimoto, M.6    Teshima, T.7
  • 25
    • 61849098239 scopus 로고    scopus 로고
    • Improved outcome of allogeneic bone marrow transplantation due to breastfeeding-induced tolerance to maternal antigens
    • Aoyama, K., M. Koyama, K. Matsuoka, D. Hashimoto, T. Ichinohe, M. Harada, K. Akashi, M. Tanimoto, and T. Teshima. 2009. Improved outcome of allogeneic bone marrow transplantation due to breastfeeding-induced tolerance to maternal antigens. Blood 113: 1829-1833.
    • (2009) Blood , vol.113 , pp. 1829-1833
    • Aoyama, K.1    Koyama, M.2    Matsuoka, K.3    Hashimoto, D.4    Ichinohe, T.5    Harada, M.6    Akashi, K.7    Tanimoto, M.8    Teshima, T.9
  • 26
    • 0032701975 scopus 로고    scopus 로고
    • IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation
    • Teshima, T., G. R. Hill, L. Pan, Y. S. Brinson, M. R. van den Brink, K. R. Cooke, and J. L. Ferrara. 1999. IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation. J. Clin. Invest. 104: 317-325.
    • (1999) J. Clin. Invest. , vol.104 , pp. 317-325
    • Teshima, T.1    Hill, G.R.2    Pan, L.3    Brinson, Y.S.4    Van Den Brink, M.R.5    Cooke, K.R.6    Ferrara, J.L.7
  • 28
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi, S., T. Yamaguchi, T. Nomura, and M. Ono. 2008. Regulatory T cells and immune tolerance. Cell 133: 775-787.
    • (2008) Cell , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 29
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi, S., N. Sakaguchi, M. Asano, M. Itoh, and M. Toda. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155: 1151-1164.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 31
    • 36348975870 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1182/blood-2007-04-086470
    • Fujita, S., Y. Sato, K. Sato, K. Eizumi, T. Fukaya, M. Kubo, N. Yamashita, and K. Sato. 2007. Regulatory dendritic cells protect against cutaneous chronic graft-ersus-host disease mediated through CD4+CD25+Foxp3+ regulatory T cells. Blood 110: 3793-3803. (Pubitemid 350159651)
    • (2007) Blood , vol.110 , Issue.10 , pp. 3793-3803
    • Fujita, S.1    Sato, Y.2    Sato, K.3    Eizumi, K.4    Fukaya, T.5    Kubo, M.6    Yamashita, N.7    Sato, K.8
  • 33
    • 0032535087 scopus 로고    scopus 로고
    • Donor-derived interferon gamma is required for inhibition of acute graft-versus-host disease by interleukin 12
    • Yang, Y. G., B. R. Dey, J. J. Sergio, D. A. Pearson, and M. Sykes. 1998. Donor-derived interferon gamma is required for inhibition of acute graft-versus-host disease by interleukin 12. J. Clin. Invest. 102: 2126-2135.
    • (1998) J. Clin. Invest. , vol.102 , pp. 2126-2135
    • Yang, Y.G.1    Dey, B.R.2    Sergio, J.J.3    Pearson, D.A.4    Sykes, M.5
  • 34
    • 0032211796 scopus 로고    scopus 로고
    • Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice
    • Murphy, W. J., L. A. Welniak, D. D. Taub, R. H. Wiltrout, P. A. Taylor, D. A. Vallera, M. Kopf, H. Young, D. L. Longo, and B. R. Blazar. 1998. Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice. J. Clin. Invest. 102: 1742-1748.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1742-1748
    • Murphy, W.J.1    Welniak, L.A.2    Taub, D.D.3    Wiltrout, R.H.4    Taylor, P.A.5    Vallera, D.A.6    Kopf, M.7    Young, H.8    Longo, D.L.9    Blazar, B.R.10
  • 35
    • 65349185574 scopus 로고    scopus 로고
    • Paradoxical effects of IFN-gamma in graft-versus-host disease reflect promotion of lymphohematopoietic graft-versus-host reactions and inhibition of epithelial tissue injury
    • Wang, H., W. Asavaroengchai, B. Y. Yeap, M. G. Wang, S. Wang, M. Sykes, and Y. G. Yang. 2009. Paradoxical effects of IFN-gamma in graft-versus-host disease reflect promotion of lymphohematopoietic graft-versus-host reactions and inhibition of epithelial tissue injury. Blood 113: 3612-3619.
    • (2009) Blood , vol.113 , pp. 3612-3619
    • Wang, H.1    Asavaroengchai, W.2    Yeap, B.Y.3    Wang, M.G.4    Wang, S.5    Sykes, M.6    Yang, Y.G.7
  • 36
    • 0034103630 scopus 로고    scopus 로고
    • Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets
    • Nikolic, B., S. Lee, R. T. Bronson, M. J. Grusby, and M. Sykes. 2000. Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets. J. Clin. Invest. 105: 1289-1298.
    • (2000) J. Clin. Invest. , vol.105 , pp. 1289-1298
    • Nikolic, B.1    Lee, S.2    Bronson, R.T.3    Grusby, M.J.4    Sykes, M.5
  • 38
    • 52649136967 scopus 로고    scopus 로고
    • Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease
    • Yi, T., D. Zhao, C. L. Lin, C. Zhang, Y. Chen, I. Todorov, T. LeBon, F. Kandeel, S. Forman, and D. Zeng. 2008. Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease. Blood 112: 2101-2110.
    • (2008) Blood , vol.112 , pp. 2101-2110
    • Yi, T.1    Zhao, D.2    Lin, C.L.3    Zhang, C.4    Chen, Y.5    Todorov, I.6    LeBon, T.7    Kandeel, F.8    Forman, S.9    Zeng, D.10
  • 40
    • 60849118676 scopus 로고    scopus 로고
    • In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations
    • Carlson, M. J., M. L. West, J. M. Coghill, A. Panoskaltsis-Mortari, B. R. Blazar, and J. S. Serody. 2009. In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations. Blood 113: 1365-1374.
    • (2009) Blood , vol.113 , pp. 1365-1374
    • Carlson, M.J.1    West, M.L.2    Coghill, J.M.3    Panoskaltsis-Mortari, A.4    Blazar, B.R.5    Serody, J.S.6
  • 41
    • 36749007248 scopus 로고    scopus 로고
    • Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells
    • Wei, J., O. Duramad, O. A. Perng, S. L. Reiner, Y. J. Liu, and F. X. Qin. 2007. Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells. Proc. Natl. Acad. Sci. USA 104: 18169-18174.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 18169-18174
    • Wei, J.1    Duramad, O.2    Perng, O.A.3    Reiner, S.L.4    Liu, Y.J.5    Qin, F.X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.