-
1
-
-
0027409793
-
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells
-
Manetti, R., P. Parronchi, M.G. Giudizi, M.-P. Piccini, E. Maggi, G. Trinchieri, and S. Romagnani. 1993. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J. Exp. Med. 177:1199-1204.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1199-1204
-
-
Manetti, R.1
Parronchi, P.2
Giudizi, M.G.3
Piccini, M.-P.4
Maggi, E.5
Trinchieri, G.6
Romagnani, S.7
-
2
-
-
0027491655
-
Interleukin-12 acts directly on CD4+ T cells to enhance priming for interferon-gamma production and diminishes interleukin-4 inhibition of such priming
-
Seder, R.A., R. Gazzinelli, A. Sher, and W.E. Paul. 1993. Interleukin-12 acts directly on CD4+ T cells to enhance priming for interferon-gamma production and diminishes interleukin-4 inhibition of such priming. Proc. Natl. Acad. Sci. USA. 90:10188-10192.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10188-10192
-
-
Seder, R.A.1
Gazzinelli, R.2
Sher, A.3
Paul, W.E.4
-
3
-
-
0029847368
-
Functional diversity of helper T lymphocytes
-
Abbas, A.K., K.M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nat. 383:787-793.
-
(1996)
Nat.
, vol.383
, pp. 787-793
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
4
-
-
16044363695
-
IL-12-deficient mice are defective in IFNγ production and type 1 cytokine responses
-
Magram, J., S.E. Connaughton, R.R. Warrier, D.M. Carvajal, C.-Y. Wu, J. Ferrante, C. Stewart, U. Sarmiento, D.A. Faherty, and M.K. Gately. 1996. IL-12-deficient mice are defective in IFNγ production and type 1 cytokine responses. Immunity. 4:471-481.
-
(1996)
Immunity
, vol.4
, pp. 471-481
-
-
Magram, J.1
Connaughton, S.E.2
Warrier, R.R.3
Carvajal, D.M.4
Wu, C.-Y.5
Ferrante, J.6
Stewart, C.7
Sarmiento, U.8
Faherty, D.A.9
Gately, M.K.10
-
5
-
-
0027971672
-
IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versus-host disease
-
Via, C.S., V. Rus, M.K. Gately, and F.D. Finkelman. 1994. IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versus-host disease. J. Immnnol. 153: 4040-4047.
-
(1994)
J. Immnnol.
, vol.153
, pp. 4040-4047
-
-
Via, C.S.1
Rus, V.2
Gately, M.K.3
Finkelman, F.D.4
-
6
-
-
0030006734
-
IL-12 is a central mediator of acute graft-versus-host disease in mice
-
Williamson, E., P. Garside, J.A. Bradley, and A.M. Mowat. 1996. IL-12 is a central mediator of acute graft-versus-host disease in mice. J. Immunol. 157: 689-699.
-
(1996)
J. Immunol.
, vol.157
, pp. 689-699
-
-
Williamson, E.1
Garside, P.2
Bradley, J.A.3
Mowat, A.M.4
-
7
-
-
0031202296
-
Neutralizing IL-12 during induction of murine acute graft-versus-host disease polarizes the cytokine profile toward a Th2-type alloimmune response and confers long term protection from disease
-
Williamson, E., P. Garside, J.A. Bradley, I.A.R. More, and A.M. Mowat. 1997. Neutralizing IL-12 during induction of murine acute graft-versus-host disease polarizes the cytokine profile toward a Th2-type alloimmune response and confers long term protection from disease. J. Immunol. 159:1208-1215.
-
(1997)
J. Immunol.
, vol.159
, pp. 1208-1215
-
-
Williamson, E.1
Garside, P.2
Bradley, J.A.3
More, I.A.R.4
Mowat, A.M.5
-
8
-
-
0029114990
-
Interleukin-12 inhibits murine graft-vs-host disease
-
Sykes, M., G.L. Szot, P.L. Nguyen, and D.A. Pearson. 1995. Interleukin-12 inhibits murine graft-vs-host disease. Blood. 86:2429-2438.
-
(1995)
Blood
, vol.86
, pp. 2429-2438
-
-
Sykes, M.1
Szot, G.L.2
Nguyen, P.L.3
Pearson, D.A.4
-
9
-
-
0030709464
-
Interleukin-12 preserves the graft-versus-leukemia effect of allogeneic CDS T cells while inhibiting CD4-dependent graft-versus-host disease in mice
-
Yang, Y.-G., J.J. Sergio, D.A. Pearson, G.L. Szot, A. Shimizu, and M. Sykes. 1997. Interleukin-12 preserves the graft-versus-leukemia effect of allogeneic CDS T cells while inhibiting CD4-dependent graft-versus-host disease in mice. Blood. 90:4651-4660.
-
(1997)
Blood
, vol.90
, pp. 4651-4660
-
-
Yang, Y.-G.1
Sergio, J.J.2
Pearson, D.A.3
Szot, G.L.4
Shimizu, A.5
Sykes, M.6
-
10
-
-
0030724881
-
IL-12 prevents severe acute GVHD and GVHD-associated immune dysfunction in a full MHC haplotype-mismatched murine bone marrow transplantation model
-
Yang, Y.-G., B. Dey, J.J. Sergio, and M. Sykes. 1997. IL-12 prevents severe acute GVHD and GVHD-associated immune dysfunction in a full MHC haplotype-mismatched murine bone marrow transplantation model. Transplantation. 64:1343-1352.
-
(1997)
Transplantation
, vol.64
, pp. 1343-1352
-
-
Yang, Y.-G.1
Dey, B.2
Sergio, J.J.3
Sykes, M.4
-
11
-
-
0032079469
-
IL-12 inhibits GVHD through a Fas-mediated mechanism associated with alterations in donor T cell activation and expansion
-
Dey, B., Y.-G. Yang, G.L. Szot, D.A. Pearson, and M. Sykes. 1998. IL-12 inhibits GVHD through a Fas-mediated mechanism associated with alterations in donor T cell activation and expansion. Blood. 91:3315-3322.
-
(1998)
Blood
, vol.91
, pp. 3315-3322
-
-
Dey, B.1
Yang, Y.-G.2
Szot, G.L.3
Pearson, D.A.4
Sykes, M.5
-
12
-
-
0027963161
-
Recombinant IL-12 administration induces tumor regression in association with IFN-γ production
-
Nastala, C.L., H.D. Edington, T.G. McKinney, H. Tahara, M.A. Nalesnik, MJ. Brunda, M.K. Getely, S.F. Wolf, R.D. Schreiber, W.J. Storkus, and M.T. Lotze. 1994. Recombinant IL-12 administration induces tumor regression in association with IFN-γ production. J. Immunol. 153:1697-1706.
-
(1994)
J. Immunol.
, vol.153
, pp. 1697-1706
-
-
Nastala, C.L.1
Edington, H.D.2
McKinney, T.G.3
Tahara, H.4
Nalesnik, M.A.5
Brunda, M.J.6
Getely, M.K.7
Wolf, S.F.8
Schreiber, R.D.9
Storkus, W.J.10
Lotze, M.T.11
-
13
-
-
0028987902
-
Role of interferon-γ in mediating the antitumor efficacy of interleukin-12
-
Brunda, M.J., L. Luistro, J.A. Hendrzak, M. Fountoulakis, G. Garotta, and M.K. Gately. 1995. Role of interferon-γ in mediating the antitumor efficacy of interleukin-12. J. Immunother. 17:71-77.
-
(1995)
J. Immunother.
, vol.17
, pp. 71-77
-
-
Brunda, M.J.1
Luistro, L.2
Hendrzak, J.A.3
Fountoulakis, M.4
Garotta, G.5
Gately, M.K.6
-
14
-
-
0029021419
-
IL-12 stimulates an antiviral type 1 cytokine response but lacks adjuvant activity in IFN-γ-receptor-deficient mice
-
Schijns, V.E.C.J., B.L. Haagmans, and M.C. Horzinek. 1995. IL-12 stimulates an antiviral type 1 cytokine response but lacks adjuvant activity in IFN-γ-receptor-deficient mice. J. Immunol. 155:2525-2532.
-
(1995)
J. Immunol.
, vol.155
, pp. 2525-2532
-
-
Schijns, V.E.C.J.1
Haagmans, B.L.2
Horzinek, M.C.3
-
15
-
-
0029671118
-
Roles of IFN-γ and TNF-α in IL-12-induced T helper cell-l development
-
Wenner, CA., M.L. Guler, S.E. Macatonia, A. O'Garra, and K.M. Murphy. 1996. Roles of IFN-γ and TNF-α in IL-12-induced T helper cell-l development. J. Immunol. 156:1442-1447.
-
(1996)
J. Immunol.
, vol.156
, pp. 1442-1447
-
-
Wenner, C.A.1
Guler, M.L.2
Macatonia, S.E.3
O'Garra, A.4
Murphy, K.M.5
-
16
-
-
0028560025
-
IL-2 inhibits early increases in serum gamma Interferon levels associated with graft-versus-host disease
-
Szebeni, J., M.-G. Wang, D.A. Pearson, G.L. Szot, and M. Sykes. 1994. IL-2 inhibits early increases in serum gamma Interferon levels associated with graft-versus-host disease. Transplantation. 58:1385-1393.
-
(1994)
Transplantation
, vol.58
, pp. 1385-1393
-
-
Szebeni, J.1
Wang, M.-G.2
Pearson, D.A.3
Szot, G.L.4
Sykes, M.5
|