메뉴 건너뛰기




Volumn 9, Issue 17, 2010, Pages 3442-3448

Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure

Author keywords

Apoptosis; Mitochondrial permeability transition pore; Necrosis

Indexed keywords

MITOCHONDRIAL PERMEABILITY TRANSITION PORE;

EID: 77956403913     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.17.12944     Document Type: Review
Times cited : (23)

References (62)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26:239-57.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 2
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • Youle RJ, Strasser A. The BCL-2 protein family: Opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008; 9:47-59.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 4
    • 0034018813 scopus 로고    scopus 로고
    • Apoptosis in Alzheimer's disease - An update
    • Shimohama S. Apoptosis in Alzheimer's disease - an update. Apoptosis 2000; 5:9-16.
    • (2000) Apoptosis , vol.5 , pp. 9-16
    • Shimohama, S.1
  • 5
    • 0032942973 scopus 로고    scopus 로고
    • Apoptosis in the effector phase of autoimmune diabetes, multiple sclerosis and thyroiditis
    • Ohsako S, Elkon KB. Apoptosis in the effector phase of autoimmune diabetes, multiple sclerosis and thyroiditis. Cell Death Differ 1999; 6:13-21. (Pubitemid 29051850)
    • (1999) Cell Death and Differentiation , vol.6 , Issue.1 , pp. 13-21
    • Ohsako, S.1    Elkon, K.B.2
  • 7
    • 57649181391 scopus 로고    scopus 로고
    • Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
    • Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008; 135:1311-23.
    • (2008) Cell , vol.135 , pp. 1311-1323
    • Hitomi, J.1    Christofferson, D.E.2    Ng, A.3    Yao, J.4    Degterev, A.5    Xavier, R.J.6
  • 8
    • 0035197969 scopus 로고    scopus 로고
    • Autoimmune type 1 diabetes: Resolved and unresolved issues
    • DOI 10.1172/JCI200114257
    • Notkins AL, Lernmark A. Autoimmune type 1 diabetes: resolved and unresolved issues. J Clin Invest 2001; 108:1247-52. (Pubitemid 33107747)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.9 , pp. 1247-1252
    • Notkins, A.L.1    Lernmark, A.2
  • 9
    • 0029022819 scopus 로고
    • Pancreatic beta-cell dysfunction as the primary genetic lesion in NIDDM. Evidence from studies in normal glucose-tolerant individuals with a first-degree NIDDM relative
    • Pimenta W, Korytkowski M, Mitrakou A, Jenssen T, Yki-Jarvinen H, Evron W, et al. Pancreatic beta-cell dysfunction as the primary genetic lesion in NIDDM. Evidence from studies in normal glucose-tolerant individuals with a first-degree NIDDM relative. JAMA 1995; 273:1855-61.
    • (1995) JAMA , vol.273 , pp. 1855-1861
    • Pimenta, W.1    Korytkowski, M.2    Mitrakou, A.3    Jenssen, T.4    Yki-Jarvinen, H.5    Evron, W.6
  • 10
    • 12344323484 scopus 로고    scopus 로고
    • Type 2 diabetes - A matter of beta-cell life and death?
    • Rhodes CJ. Type 2 diabetes-a matter of beta-cell life and death? Science 2005; 307:380-4.
    • (2005) Science , vol.307 , pp. 380-384
    • Rhodes, C.J.1
  • 11
    • 9644268967 scopus 로고    scopus 로고
    • PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance
    • DOI 10.1172/JCI200421845
    • Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn CR. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. J Clin Invest 2004; 114:828-36. (Pubitemid 39578742)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.6 , pp. 828-836
    • Kulkarni, R.N.1    Jhala, U.S.2    Winnay, J.N.3    Krajewski, S.4    Montminy, M.5    Kahn, C.R.6
  • 12
    • 0035856952 scopus 로고    scopus 로고
    • beta-cell death during progression to diabetes
    • DOI 10.1038/414792a
    • Mathis D, Vence L, Benoist C. beta-Cell death during progression to diabetes. Nature 2001; 414:792-8. (Pubitemid 34000782)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 792-798
    • Mathis, D.1    Vence, L.2    Benoist, C.3
  • 14
    • 68049143317 scopus 로고    scopus 로고
    • Bad news for beta-cell apoptosis
    • Thomas HE, Biden TJ. Bad news for beta-cell apoptosis. Diabetes 2009; 58:1725-7.
    • (2009) Diabetes , vol.58 , pp. 1725-1727
    • Thomas, H.E.1    Biden, T.J.2
  • 15
    • 67649364114 scopus 로고    scopus 로고
    • The role of inflammation in insulitis and beta-cell loss in type 1 diabetes
    • Eizirik DL, Colli ML, Ortis F. The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nat Rev Endocrinol 2009; 5:219-26.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 219-226
    • Eizirik, D.L.1    Colli, M.L.2    Ortis, F.3
  • 17
    • 0037013147 scopus 로고    scopus 로고
    • Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression
    • DOI 10.1016/S0092-8674(02)00738-9
    • Pelengaris S, Khan M, Evan GI. Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell 2002; 109:321-34. (Pubitemid 34606875)
    • (2002) Cell , vol.109 , Issue.3 , pp. 321-334
    • Pelengaris, S.1    Khan, M.2    Evan, G.I.3
  • 18
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities
    • Cnop M, Welsh N, Jonas JC, Jorns A, Lenzen S, Eizirik DL. Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 2005; 54:97-107.
    • (2005) Diabetes , vol.54 , pp. 97-107
    • Cnop, M.1    Welsh, N.2    Jonas, J.C.3    Jorns, A.4    Lenzen, S.5    Eizirik, D.L.6
  • 20
    • 21744459080 scopus 로고    scopus 로고
    • Comparative kinetic analysis reveals that inducer-specific ion release precedes the mitochondrial permeability transition
    • Krasnikov BF, Zorov DB, Antonenko YN, Zaspa AA, Kulikov IV, Kristal BS, et al. Comparative kinetic analysis reveals that inducer-specific ion release precedes the mitochondrial permeability transition. Biochim Biophys Acta 2005; 1708:375-92.
    • (2005) Biochim Biophys Acta , vol.1708 , pp. 375-392
    • Krasnikov, B.F.1    Zorov, D.B.2    Antonenko, Y.N.3    Zaspa, A.A.4    Kulikov, I.V.5    Kristal, B.S.6
  • 21
    • 68649090703 scopus 로고    scopus 로고
    • The role of the mitochondrial permeability transition pore in heart disease
    • Halestrap AP, Pasdois P. The role of the mitochondrial permeability transition pore in heart disease. Biochim Biophys Acta 2009; 1787:1402-15.
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 1402-1415
    • Halestrap, A.P.1    Pasdois, P.2
  • 22
    • 70349105567 scopus 로고    scopus 로고
    • Mitochondrial permeability transition pore opening as a promising therapeutic target in cardiac diseases
    • Javadov S, Karmazyn M, Escobales N. Mitochondrial permeability transition pore opening as a promising therapeutic target in cardiac diseases. J Pharm Exp Ther 2009; 330:670-8.
    • (2009) J Pharm Exp Ther , vol.330 , pp. 670-678
    • Javadov, S.1    Karmazyn, M.2    Escobales, N.3
  • 23
    • 0027236162 scopus 로고
    • The mitochondrial permeability transition pore may comprise VDAC molecules. II. The electrophysiological properties of VDAC are compatible with those of the mitochondrial megachannel
    • Szabo I, De Pinto V, Zoratti M. The mitochondrial permeability transition pore may comprise VDAC molecules. II. The electrophysiological properties of VDAC are compatible with those of the mitochondrial megachannel. FEBS Lett 1993; 330:206-10.
    • (1993) FEBS Lett , vol.330 , pp. 206-210
    • Szabo, I.1    De Pinto, V.2    Zoratti, M.3
  • 24
    • 0030569305 scopus 로고    scopus 로고
    • Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore
    • DOI 10.1016/0014-5793(96)01092-7, PII S0014579396010927
    • Beutner G, Ruck A, Riede B, Welte W, Brdiczka D. Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore. FEBS Lett 1996; 396:189-95. (Pubitemid 26377822)
    • (1996) FEBS Letters , vol.396 , Issue.2-3 , pp. 189-195
    • Beutner, G.1    Ruck, A.2    Riede, B.3    Welte, W.4    Brdiczka, D.5
  • 26
    • 34247895697 scopus 로고    scopus 로고
    • Voltage-dependent anion channels are dispensable for mitochondrial- dependent cell death
    • DOI 10.1038/ncb1575, PII NCB1575
    • Baines CP, Kaiser RA, Sheiko T, Craigen WJ, Molkentin JD. Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death. Nat Cell Biol 2007; 9:550-5. (Pubitemid 46696536)
    • (2007) Nature Cell Biology , vol.9 , Issue.5 , pp. 550-555
    • Baines, C.P.1    Kaiser, R.A.2    Sheiko, T.3    Craigen, W.J.4    Molkentin, J.D.5
  • 28
    • 15844407874 scopus 로고    scopus 로고
    • Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
    • DOI 10.1038/nature03317
    • Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005; 434:652-8. (Pubitemid 40488558)
    • (2005) Nature , vol.434 , Issue.7033 , pp. 652-658
    • Nakagawa, T.1    Shimizu, S.2    Watanabe, T.3    Yamaguchi, O.4    Otsu, K.5    Yamagata, H.6    Inohara, H.7    Kubo, T.8    Tsujimoto, Y.9
  • 30
    • 53549129483 scopus 로고    scopus 로고
    • Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
    • Du H, Guo L, Fang F, Chen D, Sosunov AA, McKhann GM, et al. Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med 2008; 14:1097-105.
    • (2008) Nat Med , vol.14 , pp. 1097-1105
    • Du, H.1    Guo, L.2    Fang, F.3    Chen, D.4    Sosunov, A.A.5    McKhann, G.M.6
  • 32
    • 77953389460 scopus 로고    scopus 로고
    • Targeting cyclophilin D and the mitochondrial permeability transition enhances â-cell survival and prevents diabetes in Pdx1 deficiency
    • Fujimoto K, Chen Y, Polonsky KS, Dorn GW, 2nd. Targeting cyclophilin D and the mitochondrial permeability transition enhances â-cell survival and prevents diabetes in Pdx1 deficiency. Proc Natl Acad Sci USA 2010; 107(22):10214-9.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.22 , pp. 10214-10219
    • Fujimoto, K.1    Chen, Y.2    Polonsky, K.S.3    Dorn II, G.W.4
  • 33
    • 77952683069 scopus 로고    scopus 로고
    • Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy
    • Chen Y, Lewis W, Diwan A, Cheng EH, Matkovich SJ, Dorn GW, 2nd. Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy. Proc Natl Acad Sci USA 2010; 107:9035-42.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 9035-9042
    • Chen, Y.1    Lewis, W.2    Diwan, A.3    Cheng, E.H.4    Matkovich, S.J.5    Dorn II, G.W.6
  • 34
    • 0031031571 scopus 로고    scopus 로고
    • Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
    • DOI 10.1038/ng0197-106
    • Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Genet 1997; 15:106-10. (Pubitemid 27014961)
    • (1997) Nature Genetics , vol.15 , Issue.1 , pp. 106-110
    • Stoffers, D.A.1    Zinkin, N.T.2    Stanojevic, V.3    Clarke, W.L.4    Habener, J.F.5
  • 35
    • 0032128288 scopus 로고    scopus 로고
    • Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein
    • Stoffers DA, Stanojevic V, Habener JF. Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein. J Clin Invest 1998; 102:232-41. (Pubitemid 28323850)
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.1 , pp. 232-241
    • Stoffers, D.A.1    Stanojevic, V.2    Habener, J.F.3
  • 37
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • DOI 10.1038/371606a0
    • Jonsson J, Carlsson L, Edlund T, Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994; 371:606-9. (Pubitemid 24315741)
    • (1994) Nature , vol.371 , Issue.6498 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 39
    • 38949149704 scopus 로고    scopus 로고
    • pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
    • Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, et al. pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis. Dev Biol 2008; 314:406-17.
    • (2008) Dev Biol , vol.314 , pp. 406-417
    • Gannon, M.1    Ables, E.T.2    Crawford, L.3    Lowe, D.4    Offield, M.F.5    Magnuson, M.A.6
  • 42
    • 70350343033 scopus 로고    scopus 로고
    • Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation
    • Fujimoto K, Hanson PT, Tran H, Ford EL, Han Z, Johnson JD, et al. Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation. J Biol Chem 2009; 284:27664-73.
    • (2009) J Biol Chem , vol.284 , pp. 27664-27673
    • Fujimoto, K.1    Hanson, P.T.2    Tran, H.3    Ford, E.L.4    Han, Z.5    Johnson, J.D.6
  • 43
    • 77951901715 scopus 로고    scopus 로고
    • Cell death in the pathogenesis of heart disease: Mechanisms and significance
    • Whelan RS, Kaplinskiy V, Kitsis RN. Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu Rev Physiol 2010; 72:19-44.
    • (2010) Annu Rev Physiol , vol.72 , pp. 19-44
    • Whelan, R.S.1    Kaplinskiy, V.2    Kitsis, R.N.3
  • 44
    • 24744436182 scopus 로고    scopus 로고
    • Physiologic growth and pathologic genes in cardiac development and cardiomyopathy
    • Dorn GW, 2nd. Physiologic growth and pathologic genes in cardiac development and cardiomyopathy. Trends Cardiovasc Med 2005; 15:185-9.
    • (2005) Trends Cardiovasc Med , vol.15 , pp. 185-189
    • Dorn II, G.W.1
  • 45
    • 59449098471 scopus 로고    scopus 로고
    • Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling
    • Dorn GW, 2nd. Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling. Cardiovasc Res 2009; 81:465-73.
    • (2009) Cardiovasc Res , vol.81 , pp. 465-473
    • Dorn II, G.W.1
  • 48
    • 0032554670 scopus 로고    scopus 로고
    • Decompensation of pressure-overload hypertrophy in G alpha q-overexpressing mice
    • Sakata Y, Hoit BD, Liggett SB, Walsh RA, Dorn GW, 2nd. Decompensation of pressure-overload hypertrophy in G alpha q-overexpressing mice. Circulation 1998; 97:1488-95.
    • (1998) Circulation , vol.97 , pp. 1488-1495
    • Sakata, Y.1    Hoit, B.D.2    Liggett, S.B.3    Walsh, R.A.4    Dorn II, G.W.5
  • 52
    • 68149142474 scopus 로고    scopus 로고
    • Cardiac reanimation: Targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L
    • Dorn GW, 2nd, Kirshenbaum LA. Cardiac reanimation: targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L. Oncogene 2008; 27:158-67.
    • (2008) Oncogene , vol.27 , pp. 158-167
    • Dorn II, G.W.1    Kirshenbaum, L.A.2
  • 55
    • 38349184844 scopus 로고    scopus 로고
    • Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling and hypertrophy decompensation
    • Diwan A, Wansapura J, Syed FM, Matkovich SJ, Lorenz JN, Dorn GW, 2nd. Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling and hypertrophy decompensation. Circulation 2008; 117:396-404.
    • (2008) Circulation , vol.117 , pp. 396-404
    • Diwan, A.1    Wansapura, J.2    Syed, F.M.3    Matkovich, S.J.4    Lorenz, J.N.5    Dorn II, G.W.6
  • 56
    • 61749087672 scopus 로고    scopus 로고
    • Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death
    • Diwan A, Matkovich SJ, Yuan Q, Zhao W, Yatani A, Brown JH, et al. Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death. J Clin Invest 2009; 119:203-12.
    • (2009) J Clin Invest , vol.119 , pp. 203-212
    • Diwan, A.1    Matkovich, S.J.2    Yuan, Q.3    Zhao, W.4    Yatani, A.5    Brown, J.H.6
  • 57
    • 33644847375 scopus 로고    scopus 로고
    • 2+: Molecular determinants and functional consequences
    • 2+: Molecular determinants and functional consequences. Physiol Rev 2006; 86:369-408.
    • (2006) Physiol Rev , vol.86 , pp. 369-408
    • Rizzuto, R.1    Pozzan, T.2
  • 59
    • 22144479425 scopus 로고    scopus 로고
    • 360) prevents from irreversible injury in postischemic rat heart
    • DOI 10.1111/j.1742-4658.2005.04771.x
    • de Jesus Garcia-Rivas G, Guerrero-Hernandez A, Guerrero-Serna G, Rodriguez-Zavala JS, Zazueta C. Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart. FEBS J 2005; 272:3477-88. (Pubitemid 40979316)
    • (2005) FEBS Journal , vol.272 , Issue.13 , pp. 3477-3488
    • Garcia-Rivas, G.D.J.1    Guerrero-Hernandez, A.2    Guerrero-Serna, G.3    Rodriguez-Zavala, J.S.4    Zazueta, C.5
  • 60
    • 70349632998 scopus 로고    scopus 로고
    • Role of sarcoplasmic reticulum in mitochondrial permeability transition and cardiomyocyte death during reperfusion
    • Ruiz-Meana M, Abellan A, Miro-Casas E, Agullo E, Garcia-Dorado D. Role of sarcoplasmic reticulum in mitochondrial permeability transition and cardiomyocyte death during reperfusion. Am J Physiol Heart Circ Physiol 2009; 297:1281-9.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297 , pp. 1281-1289
    • Ruiz-Meana, M.1    Abellan, A.2    Miro-Casas, E.3    Agullo, E.4    Garcia-Dorado, D.5
  • 61
    • 67349228215 scopus 로고    scopus 로고
    • Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes
    • Odagiri K, Katoh H, Kawashima H, Tanaka T, Ohtani H, Saotome M, et al. Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes. J Mol Cell Cardiol 2009; 46:989-97.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 989-997
    • Odagiri, K.1    Katoh, H.2    Kawashima, H.3    Tanaka, T.4    Ohtani, H.5    Saotome, M.6
  • 62
    • 67649811029 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore in motor neurons: Involvement in the pathobiology of ALS mice
    • Martin LJ, Gertz B, Pan Y, Price AC, Molkentin JD, Chang Q. The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice. Exp Neurol 2009; 218:333-46.
    • (2009) Exp Neurol , vol.218 , pp. 333-346
    • Martin, L.J.1    Gertz, B.2    Pan, Y.3    Price, A.C.4    Molkentin, J.D.5    Chang, Q.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.