Physiologic growth and pathologic genes in cardiac development and cardiomyopathy

Trends in Cardiovascular Medicine

Volumn 15, Issue 5, 2005, Pages 185-189

  Dorn II, Gerald W ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MITOCHONDRIAL PROTEIN; PROTEIN NIX; UNCLASSIFIED DRUG;

APOPTOSIS; BIOLOGICAL MODEL; CARDIOMYOPATHY; EMBRYO DEVELOPMENT; GENE; GENETIC DISORDER; GENETIC MANIPULATION; GENETIC PROCEDURES; GROWTH; HEART DEVELOPMENT; HEART DISEASE; HEART HYPERTROPHY; HEART MUSCLE; HEART MUSCLE CELL; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CARDIOMYOPATHIES; CARDIOMYOPATHY, HYPERTROPHIC; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEART; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIAL PROTEINS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 24744436182     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcm.2005.05.009     Document Type: Review

References (34)

1. J.W. Adams, Y. Sakata, and M.G. Davis Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure Proc. Natl. Acad. Sci. U.S.A. 95 1998 10140 10145
2. S.A. Akhter, L.M. Luttrell, and H.A. Rockman Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy Science 280 1998 574 577
3. B.J. Aronow, T. Toyokawa, and A. Canning Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy Physiol. Genomics 6 2001 19 28
4. G. Chen, J. Cizeau, and V.C. Vande Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins J. Biol. Chem. 274 1999 7 10
5. M.T. Crow Hypoxia, BNip3 proteins, and the mitochondrial death pathway in cardiomyocytes Circ. Res. 91 2002 183 185
6. D.D. D'Angelo, Y. Sakata, and J.N. Lorenz Transgenic Galphaq overexpression induces cardiac contractile failure in mice Proc. Natl. Acad. Sci. U.S.A. 94 1997 8121 8126
7. L.J. De Windt, H.W. Lim, and T. Taigen Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: an apoptosis-independent model of dilated heart failure Circ. Res. 86 2000 255 263
8. G.W. Dorn II, and J.H. Brown Gq signaling in cardiac adaptation and maladaptation Trends Cardiovasc. Med. 9 1999 26 34
9. G.W. Dorn II, N.M. Tepe, and J.N. Lorenz Low- and high-level transgenic expression of beta2-adrenergic receptors differentially affect cardiac hypertrophy and function in Galphaq-overexpressing mice Proc. Natl. Acad. Sci. U.S.A. 96 1999 6400 6405
10. S.A. Fisher, B.L. Langille, and D. Srivastava Apoptosis during cardiovascular development Circ. Res. 87 2000 856 864
11. W. Grossman, D. Jones, and L.P. McLaurin Wall stress and patterns of hypertrophy in the human left ventricle J. Clin. Invest. 56 1975 56 64
12. H.S. Hahn, M.G. Yussman, and T. Toyokawa Ischemic protection and myofibrillar cardiomyopathy: dose-dependent effects of in vivo deltaPKC inhibition Circ. Res. 91 2002 741 748
13. Y. Hayakawa, M. Chandra, and W. Miao Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice Circulation 108 2003 3036 3041
14. L.A. Kubasiak, O.M. Hernandez, N.H. Bishopric, and K.A. Webster Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3 Proc. Natl. Acad. Sci. U.S.A. 99 2002 12825 12830
15. F. Li, X. Wang, J.M. Capasso, and A.M. Gerdes Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development J. Mol. Cell. Cardiol. 28 1996 1737 1746
16. T. Minamino, T. Yujiri, and N. Terada MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq Proc. Natl. Acad. Sci. U.S.A. 99 2002 3866 3871
17. H. Morita, J. Seidman, and C.E. Seidman Genetic causes of human heart failure J. Clin. Invest. 115 2005 518 526
18. S. Offermanns, C.F. Toombs, Y.H. Hu, and M.I. Simon Defective platelet activation in G alpha(q)-deficient mice Nature 389 1997 183 186
19. S. Offermanns, L.P. Zhao, and A. Gohla Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice EMBO J. 17 1998 4304 4312
20. K.M. Regula, K. Ens, and L.A. Kirshenbaum Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes Circ. Res. 91 2002 226 231
21. H.A. Rockman, R.S. Ross, and A.N. Harris Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy Proc. Natl. Acad. Sci. U.S.A. 88 1991 8277 8281
22. Y. Sakata, B.D. Hoit, and S.B. Liggett Decompensation of pressure-overload hypertrophy in G alpha q-overexpressing mice Circulation 97 1998 1488 1495
23. A. Sanbe, J. Gulick, and M.C. Hanks Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter Circ. Res. 92 2003 609 616
24. M.I. Simon, M.P. Strathmann, and N. Gautam Diversity of G proteins in signal transduction Science 252 1991 802 808
25. K.M. Small, D.W. McGraw, and S.B. Liggett Pharmacology and physiology of human adrenergic receptor polymorphisms Annu. Rev. Pharmacol. Toxicol. 43 2003 381 411
26. D.S. Sohal, M. Nghiem, and M.A. Crackower Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein Circ. Res. 89 2001 20 25
27. Q. Song, A.G. Schmidt, and H.S. Hahn Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy J. Clin. Invest. 111 2003 859 867
28. A. Subramaniam, W.K. Jones, and J. Gulick Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice J. Biol. Chem. 266 1991 24613 24620
29. F. Syed, A. Odley, and H.S. Hahn Physiological growth synergizes with pathological genes in experimental cardiomyopathy Circ. Res. 95 2004 1200 1206
30. W.S. Webster Teratogen update: congenital rubella Teratology 58 1998 13 23
31. N. Wettschureck, H. Rutten, and A. Zywietz Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytes Nat. Med. 7 2001 1236 1240
32. T.M. Wilkie, P.A. Scherle, and M.P. Strathmann Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines Proc. Natl. Acad. Sci. U.S.A. 88 1991 10049 10053
33. G. Wu, T. Toyokawa, H. Hahn, and G.W. Dorn II Epsilon protein kinase C in pathological myocardial hypertrophy. Analysis by combined transgenic expression of translocation modifiers and Gaq J. Biol. Chem. 275 2000 29927 29930
34. M.G. Yussman, T. Toyokawa, and A. Odley Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy Nat. Med. 8 2002 725 730