Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system

RNA

Volumn 6, Issue 7, 2000, Pages 1044-1055

  Manuvakhova, Marina ^a,c   Keeling, Kim ^b   Bedwell, David M ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Aminoglycosides; Mammals; Readthrough; Suppression; Termination; Trans lation

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; GENTAMICIN; HYGROMYCIN B; KANAMYCIN A; KANAMYCIN B; LIVIDOMYCIN; NEOMYCIN; PAROMOMYCIN; STREPTOMYCIN; TOBRAMYCIN; TRANSFER RNA;

ARTICLE; BASE PAIRING; DNA FLANKING REGION; DRUG BINDING; GENE REPRESSION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; RNA SEQUENCE; RNA TRANSLATION; STOP CODON;

ANIMALS; ANTI-BACTERIAL AGENTS; CINNAMATES; CODON, TERMINATOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; GENES, REPORTER; GENTAMICINS; HUMANS; HYGROMYCIN B; KANAMYCIN; NEOMYCIN; PAROMOMYCIN; PLASMIDS; PROTEIN BIOSYNTHESIS; RABBITS; RETICULOCYTES; RIBOSOMES; RNA, MESSENGER; SISOMICIN; STREPTOMYCIN; TOBRAMYCIN;

EUKARYOTA; MAMMALIA;

EID: 0033929810     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838200000716     Document Type: Article

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