-
1
-
-
0037134046
-
Allergy, parasites, and the hygiene hypothesis
-
Yazdanbakhsh M, Kremsner PG, Van Ree R. Allergy, parasites, and the hygiene hypothesis. Science 2002; 296:490-494.
-
(2002)
Science
, vol.296
, pp. 490-494
-
-
Yazdanbakhsh, M.1
Kremsner, P.G.2
Van Ree, R.3
-
2
-
-
33750350343
-
Allergy and hypersensitivity: Mechanisms of allergic disease
-
Akdis CA. Allergy and hypersensitivity: mechanisms of allergic disease. Curr Opin Immunol 2006; 18:718-726.
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 718-726
-
-
Akdis, C.A.1
-
3
-
-
23244437654
-
Innate immune responses to infection
-
quiz 250
-
Tosi MF. Innate immune responses to infection. J Allergy Clin Immunol 2005; 116:241-249; quiz 250.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 241-249
-
-
Tosi, M.F.1
-
4
-
-
64649093157
-
T regulatory cells and their counterparts: Masters of immune regulation
-
Ozdemir C, Akdis M, Akdis CA. T regulatory cells and their counterparts: masters of immune regulation. Clin Exp Allergy 2009; 39:626-639.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 626-639
-
-
Ozdemir, C.1
Akdis, M.2
Akdis, C.A.3
-
5
-
-
0024549594
-
Presentation of exogenous protein antigens by dendritic cells to T cell clones: Intact protein is presented best by immature, epidermal Langerhans cells
-
Romani N, Koide S, Crowley M, et al. Presentation of exogenous protein antigens by dendritic cells to T cell clones: intact protein is presented best by immature, epidermal Langerhans cells. J Exp Med 1989; 169:1169-1178.
-
(1989)
J Exp Med
, vol.169
, pp. 1169-1178
-
-
Romani, N.1
Koide, S.2
Crowley, M.3
-
6
-
-
63449090874
-
Mechanisms and treatment of allergic disease in the big picture of regulatoryT cells
-
quiz 747-1738
-
Akdis CA, Akdis M. Mechanisms and treatment of allergic disease in the big picture of regulatoryT cells. J Allergy Clin Immunol 2009; 123:735-746; quiz 747-1738
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 735-746
-
-
Akdis, C.A.1
Akdis, M.2
-
7
-
-
33749016485
-
Immunological mechanisms of allergen-specific immunotherapy
-
Larche M, Akdis CA, Valenta R. Immunological mechanisms of allergen-specific immunotherapy. Nat Rev Immunol 2006; 6:761-771.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 761-771
-
-
Larche, M.1
Akdis, C.A.2
Valenta, R.3
-
8
-
-
39449133957
-
A mechanism for the initiation of allergen-induced T helper type 2 responses
-
Sokol CL, Barton GM, Farr AG, Medzhitov R. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol 2008; 9:310-318.
-
(2008)
Nat Immunol
, vol.9
, pp. 310-318
-
-
Sokol, C.L.1
Barton, G.M.2
Farr, A.G.3
Medzhitov, R.4
-
9
-
-
67649216604
-
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response
-
Sokol CL, Chu NQ, Yu S, et al. Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat Immunol 2009; 10:713-720.
-
(2009)
Nat Immunol
, vol.10
, pp. 713-720
-
-
Sokol, C.L.1
Chu, N.Q.2
Yu, S.3
-
10
-
-
0031278414
-
Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgEbyan IL-13-dominated cytokine pattern: IgG4 counter-regulation by CLA-memory T cells
-
Akdis M, Akdis CA, Weigl L, et al. Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgEbyan IL-13-dominated cytokine pattern: IgG4 counter-regulation by CLA-memory T cells. J Immunol 1997; 159:4611-4619.
-
(1997)
J Immunol
, vol.159
, pp. 4611-4619
-
-
Akdis, M.1
Akdis, C.A.2
Weigl, L.3
-
11
-
-
0028965834
-
Circulating allergen-reactive T cells from patients with atopic dermatitis and allergic contact dermatitis express the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen
-
Santamaria Babi LF, Picker LJ, Perez Soler MT, et al. Circulating allergen-reactive T cells from patients with atopic dermatitis and allergic contact dermatitis express the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen. J Exp Med 1995; 181:1935-1940.
-
(1995)
J Exp Med
, vol.181
, pp. 1935-1940
-
-
Santamaria Babi, L.F.1
Picker, L.J.2
Perez Soler, M.T.3
-
12
-
-
0032865996
-
Elevated serum L-selectin levels and abnormal regulation of L-selectin expression on leukocytes in atopic dermatitis: Soluble L-selectin levels indicate disease severity
-
Shimada Y, Sato S, Hasegawa M, et al. Elevated serum L-selectin levels and abnormal regulation of L-selectin expression on leukocytes in atopic dermatitis: soluble L-selectin levels indicate disease severity. J Allergy Clin Immunol 1999; 104:163-168.
-
(1999)
J Allergy Clin Immunol
, vol.104
, pp. 163-168
-
-
Shimada, Y.1
Sato, S.2
Hasegawa, M.3
-
13
-
-
0025222172
-
Differential expression of homing-associated adhesion molecules by T cell subsets in man
-
Picker LJ, Terstappen LW, Rott LS, et al. Differential expression of homing-associated adhesion molecules by T cell subsets in man. J Immunol 1990; 145:3247-3255.
-
(1990)
J Immunol
, vol.145
, pp. 3247-3255
-
-
Picker, L.J.1
Terstappen, L.W.2
Rott, L.S.3
-
14
-
-
0034531692
-
Expression of cutaneous lymphocyte-associated antigen on human CD4(+) and CD8(+) Th2 cells
-
Akdis M, Klunker S, Schliz M, et al. Expression of cutaneous lymphocyte-associated antigen on human CD4(+) and CD8(+) Th2 cells. Eur J Immunol 2000; 30:3533-3541.
-
(2000)
Eur J Immunol
, vol.30
, pp. 3533-3541
-
-
Akdis, M.1
Klunker, S.2
Schliz, M.3
-
15
-
-
0028963377
-
Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production
-
Leung DY, Gately M, Trumble A, et al. Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production. J Exp Med 1995; 181:747-753.
-
(1995)
J Exp Med
, vol.181
, pp. 747-753
-
-
Leung, D.Y.1
Gately, M.2
Trumble, A.3
-
16
-
-
0032869237
-
T cells and T cell-derived cytokines as pathogenic factors in the nonallergic form of atopic dermatitis
-
Akdis CA, Akdis M, Simon D, et al. T cells and T cell-derived cytokines as pathogenic factors in the nonallergic form of atopic dermatitis. J Invest Dermatol 1999; 113:628-634.
-
(1999)
J Invest Dermatol
, vol.113
, pp. 628-634
-
-
Akdis, C.A.1
Akdis, M.2
Simon, D.3
-
17
-
-
0033168615
-
Skin homing (cutaneous lymphocyte-associated antigen-positive) CD8+ T cells respond to superantigen and contribute to eosinophilia and IgE production in atopic dermatitis
-
Akdis M, Simon HU, Weigl L, et al. Skin homing (cutaneous lymphocyte-associated antigen-positive) CD8+ T cells respond to superantigen and contribute to eosinophilia and IgE production in atopic dermatitis. J Immunol 1999; 163:466-475.
-
(1999)
J Immunol
, vol.163
, pp. 466-475
-
-
Akdis, M.1
Simon, H.U.2
Weigl, L.3
-
18
-
-
0026639775
-
Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis
-
Van Reijsen FC, Bruijnzeel-Koomen CA, Kalthoff FS, et al. Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis. J Allergy Clin Immunol 1992; 90:184-193.
-
(1992)
J Allergy Clin Immunol
, vol.90
, pp. 184-193
-
-
Van Reijsen, F.C.1
Bruijnzeel-Koomen, C.A.2
Kalthoff, F.S.3
-
19
-
-
0027222095
-
Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
-
Varney VA, HamidQA, GagaM, et al. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993; 92:644-651.
-
(1993)
J Clin Invest
, vol.92
, pp. 644-651
-
-
Varney, V.A.1
Hamid, Q.A.2
Gaga, M.3
-
20
-
-
0029856251
-
Allergen specificity of skin-infiltrating T cells is not restricted to a type-2 cytokine pattern in chronic skin lesions of atopic dermatitis
-
Werfel T, Morita A, Grewe M, et al. Allergen specificity of skin-infiltrating T cells is not restricted to a type-2 cytokine pattern in chronic skin lesions of atopic dermatitis. J Invest Dermatol 1996; 107:871-876.
-
(1996)
J Invest Dermatol
, vol.107
, pp. 871-876
-
-
Werfel, T.1
Morita, A.2
Grewe, M.3
-
21
-
-
0024210524
-
The relationship between infiltrating CD4+ lymphocytes, activated eosinophils, and the magnitude of the allergen-induced late phase cutaneous reaction in man
-
Frew AJ, Kay AB. The relationship between infiltrating CD4+ lymphocytes, activated eosinophils, and the magnitude of the allergen-induced late phase cutaneous reaction in man. J Immunol 1988; 141:4158-4164.
-
(1988)
J Immunol
, vol.141
, pp. 4158-4164
-
-
Frew, A.J.1
Kay, A.B.2
-
22
-
-
0028804437
-
Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen
-
Abernathy-Carver KJ, Sampson HA, Picker LJ, Leung DY. Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. J Clin Invest 1995; 95:913-918.
-
(1995)
J Clin Invest
, vol.95
, pp. 913-918
-
-
Abernathy-Carver, K.J.1
Sampson, H.A.2
Picker, L.J.3
Leung, D.Y.4
-
23
-
-
0037251961
-
Clinical and immunologic reactivity to aeroallergens in 'intrinsic' atopic dermatitis patients
-
Kerschenlohr K, Decard S, Darsow U, et al. Clinical and immunologic reactivity to aeroallergens in 'intrinsic' atopic dermatitis patients. J Allergy Clin Immunol 2003; 111:195-197.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 195-197
-
-
Kerschenlohr, K.1
Decard, S.2
Darsow, U.3
-
24
-
-
0027982108
-
Toxoplasma gondii possesses a superantigen activity that selectively expands murineTcell receptor v beta 5-bearing CD8+ lymphocytes
-
Denkers EY, Caspar P, Sher A. Toxoplasma gondii possesses a superantigen activity that selectively expands murineTcell receptor V beta 5-bearing CD8+ lymphocytes. J Exp Med 1994; 180:985-994.
-
(1994)
J Exp Med
, vol.180
, pp. 985-994
-
-
Denkers, E.Y.1
Caspar, P.2
Sher, A.3
-
25
-
-
0030959873
-
V beta 8+CD4-CD8-subpopulation induced by staphylococcal enterotoxin B
-
Chou MC, Lee SC, Lin YS, Lei HY. V beta 8+CD4-CD8-subpopulation induced by staphylococcal enterotoxin B. Immunol Lett 1997; 55:85-91.
-
(1997)
Immunol Lett
, vol.55
, pp. 85-91
-
-
Chou, M.C.1
Lee, S.C.2
Lin, Y.S.3
Lei, H.Y.4
-
26
-
-
24644475365
-
The cradle of IgE autoreactivity in atopic eczema lies in early infancy
-
Mothes N, Niggemann B, Jenneck C, et al. The cradle of IgE autoreactivity in atopic eczema lies in early infancy. J Allergy Clin Immunol 2005; 116:706-709.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 706-709
-
-
Mothes, N.1
Niggemann, B.2
Jenneck, C.3
-
27
-
-
0031764786
-
Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients
-
Natter S, Seiberler S, Hufnagl P, et al. Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients. FASEB J 1998; 12:1559-1569.
-
(1998)
FASEB J
, vol.12
, pp. 1559-1569
-
-
Natter, S.1
Seiberler, S.2
Hufnagl, P.3
-
28
-
-
0034029426
-
Autoallergy: A pathogenetic factor in atopic dermatitis?
-
Valenta R, Seiberler S, Natter S, et al. Autoallergy: a pathogenetic factor in atopic dermatitis? J Allergy Clin Immunol 2000; 105:432-437.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 432-437
-
-
Valenta, R.1
Seiberler, S.2
Natter, S.3
-
30
-
-
0033582629
-
Reciprocal control of T helper cell and dendritic cell differentiation
-
Rissoan MC, SoumelisV, Kadowaki N, et al. Reciprocal control of T helper cell and dendritic cell differentiation. Science 1999; 283:1183-1186.
-
(1999)
Science
, vol.283
, pp. 1183-1186
-
-
Rissoan, M.C.1
Soumelis, V.2
Kadowaki, N.3
-
31
-
-
33644752743
-
Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells
-
Ito T, Kanzler H, Duramad O, et al. Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells. Blood 2006; 107:2423-2431.
-
(2006)
Blood
, vol.107
, pp. 2423-2431
-
-
Ito, T.1
Kanzler, H.2
Duramad, O.3
-
32
-
-
33846438598
-
Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand
-
Ito T, Yang M, Wang YH, et al. Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand. J Exp Med 2007; 204:105-115.
-
(2007)
J Exp Med
, vol.204
, pp. 105-115
-
-
Ito, T.1
Yang, M.2
Wang, Y.H.3
-
33
-
-
0035179882
-
Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
-
Jarrossay D, Napolitani G, Colonna M, et al. Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur J Immunol 2001; 31:3388-3393.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3388-3393
-
-
Jarrossay, D.1
Napolitani, G.2
Colonna, M.3
-
34
-
-
0035903288
-
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
-
Kadowaki N, Ho S, Antonenko S, et al. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 2001; 194:863-869.
-
(2001)
J Exp Med
, vol.194
, pp. 863-869
-
-
Kadowaki, N.1
Ho, S.2
Antonenko, S.3
-
35
-
-
3142720367
-
Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
-
De Heer HJ, Hammad H, Soullie T, et al. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med 2004; 200:89-98.
-
(2004)
J Exp Med
, vol.200
, pp. 89-98
-
-
De Heer, H.J.1
Hammad, H.2
Soullie, T.3
-
36
-
-
37049020707
-
Dendritic cells in asthma and COPD: Opportunities for drug development
-
Kool M, Lambrecht BN. Dendritic cells in asthma and COPD: opportunities for drug development. Curr Opin Immunol 2007; 19:701-710.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 701-710
-
-
Kool, M.1
Lambrecht, B.N.2
-
37
-
-
0029922964
-
Immunomorphological and ultra-structural characterization of Langerhans cells and a novel, inflammatory dendritic epidermal cell (IDEC) population in lesional skin of atopic eczema
-
Wollenberg A, Kraft S, Hanau D, Bieber T. Immunomorphological and ultra-structural characterization of Langerhans cells and a novel, inflammatory dendritic epidermal cell (IDEC) population in lesional skin of atopic eczema. J Invest Dermatol 1996; 106:446-453.
-
(1996)
J Invest Dermatol
, vol.106
, pp. 446-453
-
-
Wollenberg, A.1
Kraft, S.2
Hanau, D.3
Bieber, T.4
-
38
-
-
22044432022
-
The role of dendritic cell subtypes in the pathophysiology of atopic dermatitis
-
Novak N, Bieber T. The role of dendritic cell subtypes in the pathophysiology of atopic dermatitis. J Am Acad Dermatol 2005; 53:S171-S176.
-
(2005)
J Am Acad Dermatol
, vol.53
-
-
Novak, N.1
Bieber, T.2
-
39
-
-
0025797232
-
IgE-bearing Langerhans cells are not specific to atopic eczema but are found in inflammatory skin diseases
-
Bieber T, Braun-Falco O. IgE-bearing Langerhans cells are not specific to atopic eczema but are found in inflammatory skin diseases. J Am Acad Dermatol 1991; 24:658-659.
-
(1991)
J Am Acad Dermatol
, vol.24
, pp. 658-659
-
-
Bieber, T.1
Braun-Falco, O.2
-
40
-
-
77953414965
-
The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo
-
Collington SJ, Hallgren J, Pease JE, et al. The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo. J Immunol 2010; 184:611 4-6123.
-
(2010)
J Immunol
, vol.184
, pp. 6114-6123
-
-
Collington, S.J.1
Hallgren, J.2
Pease, J.E.3
-
41
-
-
67449168402
-
Zinc transporter Znt5/Slc30a5 is required for the mast cell-mediated delayed-type allergic reaction but not the immediate-type reaction
-
Nishida K, Hasegawa A, Nakae S, et al. Zinc transporter Znt5/Slc30a5 is required for the mast cell-mediated delayed-type allergic reaction but not the immediate-type reaction. J Exp Med 2009; 206:1351-1364.
-
(2009)
J Exp Med
, vol.206
, pp. 1351-1364
-
-
Nishida, K.1
Hasegawa, A.2
Nakae, S.3
-
42
-
-
0036201876
-
Human NK1 and NK2 subsets determined by purification of IFN-gamma-secreting and IFN-gamma-nonsecreting NK cells
-
Deniz G, Akdis M, Aktas E, et al. Human NK1 and NK2 subsets determined by purification of IFN-gamma-secreting and IFN-gamma-nonsecreting NK cells. Eur J Immunol 2002; 32:879-884.
-
(2002)
Eur J Immunol
, vol.32
, pp. 879-884
-
-
Deniz, G.1
Akdis, M.2
Aktas, E.3
-
43
-
-
73349104119
-
Natural killer cells in atopic and autoimmune diseases of the skin
-
von Bubnoff D, Andres E, Hentges F, et al. Natural killer cells in atopic and autoimmune diseases of the skin. J Allergy Clin Immunol 2010; 125:60-68.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 60-68
-
-
Von Bubnoff, D.1
Andres, E.2
Hentges, F.3
-
44
-
-
76249118744
-
CD56highCD16-CD62L-NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses
-
Carbone T, Nasorri F, Pennino D, et al. CD56highCD16-CD62L-NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses. J Immunol 2010; 184:1102-1110.
-
(2010)
J Immunol
, vol.184
, pp. 1102-1110
-
-
Carbone, T.1
Nasorri, F.2
Pennino, D.3
-
45
-
-
0022640843
-
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
-
Mosmann TR, Cherwinski H, Bond MW, et al. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-2357.
-
(1986)
J Immunol
, vol.136
, pp. 2348-2357
-
-
Mosmann, T.R.1
Cherwinski, H.2
Bond, M.W.3
-
46
-
-
68249141746
-
Therapeutic manipulation of immune tolerance in allergic disease
-
Akdis M, Akdis CA. Therapeutic manipulation of immune tolerance in allergic disease. Nat Rev Drug Discov 2009; 8:645-660.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 645-660
-
-
Akdis, M.1
Akdis, C.A.2
-
47
-
-
77952584843
-
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflamma tion
-
Chang HC, Sehra S, Goswami R, et al. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflamma tion. Nat Immunol 2010; 11:527-534.
-
(2010)
Nat Immunol
, vol.11
, pp. 527-534
-
-
Chang, H.C.1
Sehra, S.2
Goswami, R.3
-
48
-
-
33845930300
-
Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration
-
Wells JW, Cowled CJ, Giorgini A, et al. Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration. J Allergy Clin Immunol 2007; 119:226-234.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 226-234
-
-
Wells, J.W.1
Cowled, C.J.2
Giorgini, A.3
-
50
-
-
34249799275
-
Coming back to a missing immune deviation as the main explanatory mechanism for the hygiene hypothesis
-
Romagnani S. Coming back to a missing immune deviation as the main explanatory mechanism for the hygiene hypothesis. J Allergy Clin Immunol 2007; 119:1511-1513.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1511-1513
-
-
Romagnani, S.1
-
51
-
-
41449083897
-
T-cell effector pathways in allergic diseases: Transcriptional mechanisms and therapeutic targets
-
quiz 824-1815
-
Chatila TA, Li N, Garcia-Lloret M, et al. T-cell effector pathways in allergic diseases: transcriptional mechanisms and therapeutic targets. J Allergy Clin Immunol 2008; 121:812-823; quiz 824-1815
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 812-823
-
-
Chatila, T.A.1
Li, N.2
Garcia-Lloret, M.3
-
52
-
-
33847331537
-
T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways
-
Fujiwara M, Hirose K, Kagami S, et al. T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways. J Allergy Clin Immunol 2007; 119:662-670.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 662-670
-
-
Fujiwara, M.1
Hirose, K.2
Kagami, S.3
-
53
-
-
38149039248
-
T cell-specific T-box transcription factor haplotype is associated with allergic asthma in children
-
Munthe-Kaas MC, Carlsen KH, Haland G, et al. T cell-specific T-box transcription factor haplotype is associated with allergic asthma in children. J Allergy Clin Immunol 2008; 121:51-56.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 51-56
-
-
Munthe-Kaas, M.C.1
Carlsen, K.H.2
Haland, G.3
-
54
-
-
40049084327
-
Increased activation-induced cell death of high IFN-gamma-producing T(H)1 cells as a mechanism of T(H)2 predominance in atopic diseases
-
Akkoc T, de Koning PJ, Ruckert B, et al. Increased activation-induced cell death of high IFN-gamma-producing T(H)1 cells as a mechanism of T(H)2 predominance in atopic diseases. J Allergy Clin Immunol 2008, 121:652-658 e651.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 652-658
-
-
Akkoc, T.1
De Koning, P.J.2
Ruckert, B.3
-
55
-
-
0033932896
-
T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis
-
Trautmann A, Akdis M, Kleemann D, et al. T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis. J Clin Invest 2000; 106:25-35.
-
(2000)
J Clin Invest
, vol.106
, pp. 25-35
-
-
Trautmann, A.1
Akdis, M.2
Kleemann, D.3
-
56
-
-
0036169602
-
T cells and eosinophils cooperate in the induction of bronchial epithelial cell apoptosis in asthma
-
Trautmann A, Schmid-Grendelmeier P, Kruger K, et al. T cells and eosinophils cooperate in the induction of bronchial epithelial cell apoptosis in asthma. J Allergy Clin Immunol 2002; 109:329-337.
-
(2002)
J Allergy Clin Immunol
, vol.109
, pp. 329-337
-
-
Trautmann, A.1
Schmid-Grendelmeier, P.2
Kruger, K.3
-
57
-
-
0038387249
-
Et al.T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells
-
Akdis M, Trautmann A, Klunker S, et al.T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells. FASEB J 2003; 17:1026-1035.
-
(2003)
FASEB J
, vol.17
, pp. 1026-1035
-
-
Akdis, M.1
Trautmann, A.2
Klunker, S.3
-
58
-
-
7044286403
-
Apoptosis in tissue inflammation and allergic disease
-
Akdis CA, Blaser K, Akdis M. Apoptosis in tissue inflammation and allergic disease. Curr Opin Immunol 2004; 16:717-723.
-
(2004)
Curr Opin Immunol
, vol.16
, pp. 717-723
-
-
Akdis, C.A.1
Blaser, K.2
Akdis, M.3
-
59
-
-
77950369161
-
IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic derma titis
-
Meyer N, Zimmermann M, Burgler S, et al. IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic derma titis. J Allergy Clin Immunol 2010; 125:858-865.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 858-865
-
-
Meyer, N.1
Zimmermann, M.2
Burgler, S.3
-
60
-
-
67649233028
-
IL-27 is expressed in chronic human eczematous skin lesions and stimulates human keratinocytes
-
Wittmann M, Zeitvogel J, Wang D, Werfel T. IL-27 is expressed in chronic human eczematous skin lesions and stimulates human keratinocytes. J Allergy Clin Immunol 2009; 124:81-89.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 81-89
-
-
Wittmann, M.1
Zeitvogel, J.2
Wang, D.3
Werfel, T.4
-
61
-
-
33750538236
-
Regulation of the T cell response
-
Romagnani S. Regulation of the T cell response. Clin Exp Allergy 2006; 36:1357-1366.
-
(2006)
Clin Exp Allergy
, vol.36
, pp. 1357-1366
-
-
Romagnani, S.1
-
62
-
-
77951890216
-
IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation
-
Sehra S, Yao Y, Howell MD, et al. IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation. J Immunol 2010; 184: 3186-3190.
-
(2010)
J Immunol
, vol.184
, pp. 3186-3190
-
-
Sehra, S.1
Yao, Y.2
Howell, M.D.3
-
63
-
-
0032213337
-
OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4-producing effectors
-
Ohshima Y, Yang LP, Uchiyama T, et al. OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4-producing effectors. Blood 1998; 92:3338-3345.
-
(1998)
Blood
, vol.92
, pp. 3338-3345
-
-
Ohshima, Y.1
Yang, L.P.2
Uchiyama, T.3
-
64
-
-
34547097277
-
Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation
-
quiz 245-1236
-
Liu YJ. Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation. J Allergy Clin Immunol 2007; 120:238-244; quiz 245-1236
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 238-244
-
-
Liu, Y.J.1
-
65
-
-
0030044161
-
Characterization of thymic stromal-derived lymphopoietin (TSLP) in murine B cell development in vitro
-
Ray RJ, Furlonger C, Williams DE, Paige CJ. Characterization of thymic stromal-derived lymphopoietin (TSLP) in murine B cell development in vitro. Eur J Immunol 1996; 26:10-16.
-
(1996)
Eur J Immunol
, vol.26
, pp. 10-16
-
-
Ray, R.J.1
Furlonger, C.2
Williams, D.E.3
Paige, C.J.4
-
66
-
-
27744510433
-
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
-
Ito T, Wang YH, Duramad O, et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J Exp Med 2005; 202:1213-1223.
-
(2005)
J Exp Med
, vol.202
, pp. 1213-1223
-
-
Ito, T.1
Wang, Y.H.2
Duramad, O.3
-
67
-
-
55149088554
-
Regulation and pro-inflammatory function of interleukin-17 family cytokines
-
Dong C. Regulation and pro-inflammatory function of interleukin-17 family cytokines. Immunol Rev 2008; 226:80-86.
-
(2008)
Immunol Rev
, vol.226
, pp. 80-86
-
-
Dong, C.1
-
68
-
-
36749051929
-
Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma
-
Ballantyne SJ, Barlow JL, Jolin HE, et al. Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma. J Allergy Clin Immunol 2007; 120: 1324-1331.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 1324-1331
-
-
Ballantyne, S.J.1
Barlow, J.L.2
Jolin, H.E.3
-
69
-
-
27744446058
-
IL-33,an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J, Owyang A, Oldham E, et al. IL-33,an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005; 23:479-490.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
-
70
-
-
77953728457
-
Over-expression of IL-33 leads to spontaneous pulmonary inflammation in mIL-33 transgenic mice
-
Zhiguang X, Wei C, Steven R, et al. Over-expression of IL-33 leads to spontaneous pulmonary inflammation in mIL-33 transgenic mice. Immunol Lett 2010; 131:159-165.
-
(2010)
Immunol Lett
, vol.131
, pp. 159-165
-
-
Zhiguang, X.1
Wei, C.2
Steven, R.3
-
71
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
72
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan PR, Harrington LE, O'Quinn DB, et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 2006; 441:231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
-
73
-
-
70449698029
-
Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13
-
e761
-
He R, Kim HY, Yoon J, et al. Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy Clin Immunol 2009; 124:761-770 e761.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 761-770
-
-
He, R.1
Kim, H.Y.2
Yoon, J.3
-
74
-
-
0037216818
-
Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma
-
Hellings PW, Kasran A, Liu Z, et al. Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am J Respir Cell Mol Biol 2003; 28:42-50.
-
(2003)
Am J Respir Cell Mol Biol
, vol.28
, pp. 42-50
-
-
Hellings, P.W.1
Kasran, A.2
Liu, Z.3
-
75
-
-
24344469562
-
Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation
-
Sergejeva S, Ivanov S, Lotvall J, Linden A. Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation. Am J Respir Cell Mol Biol 2005; 33:248-253.
-
(2005)
Am J Respir Cell Mol Biol
, vol.33
, pp. 248-253
-
-
Sergejeva, S.1
Ivanov, S.2
Lotvall, J.3
Linden, A.4
-
76
-
-
70349290628
-
Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response
-
Oyoshi MK, Elkhal A, Kumar L, et al. Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response. Proc Natl Acad Sci USA 2009; 106:14954-14959.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14954-14959
-
-
Oyoshi, M.K.1
Elkhal, A.2
Kumar, L.3
-
77
-
-
67349127266
-
Prostaglandin E2-EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
-
Yao C, Sakata D, Esaki Y, et al. Prostaglandin E2-EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion. Nat Med 2009; 15:633-640.
-
(2009)
Nat Med
, vol.15
, pp. 633-640
-
-
Yao, C.1
Sakata, D.2
Esaki, Y.3
-
78
-
-
56349093347
-
IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells
-
Dardalhon V, Awasthi A, Kwon H, et al. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol 2008; 9:1347-1355.
-
(2008)
Nat Immunol
, vol.9
, pp. 1347-1355
-
-
Dardalhon, V.1
Awasthi, A.2
Kwon, H.3
-
79
-
-
56349154943
-
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
-
Veldhoen M, UyttenhoveC, Van Snick J, et al. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol 2008; 9:1341-1346.
-
(2008)
Nat Immunol
, vol.9
, pp. 1341-1346
-
-
Veldhoen, M.1
Uyttenhove, C.2
Van Snick, J.3
-
80
-
-
67650502393
-
Th9 and allergic disease
-
Soroosh P, Doherty TA. Th9 and allergic disease. Immunology 2009; 127:450-458.
-
(2009)
Immunology
, vol.127
, pp. 450-458
-
-
Soroosh, P.1
Doherty, T.A.2
-
81
-
-
67649161002
-
IL-22-producing 'T22' T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-1 7-producing TH17 T cells
-
Nograles KE, Zaba LC, Shemer A, et al. IL-22-producing 'T22' T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-1 7-producing TH17 T cells. J Allergy Clin Immunol 2009; 123:1244-1252 e1242.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 1244-1252
-
-
Nograles, K.E.1
Zaba, L.C.2
Shemer, A.3
-
82
-
-
67651154105
-
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
-
Duhen T, Geiger R, Jarrossay D, et al. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 2009; 10:857-863.
-
(2009)
Nat Immunol
, vol.10
, pp. 857-863
-
-
Duhen, T.1
Geiger, R.2
Jarrossay, D.3
-
83
-
-
2342444617
-
Full house: 12 receptors for 27 cytokines
-
Kotenko SV, Langer JA. Full house: 12 receptors for 27 cytokines. Int Immunopharmacol 2004; 4:593-608.
-
(2004)
Int Immunopharmacol
, vol.4
, pp. 593-608
-
-
Kotenko, S.V.1
Langer, J.A.2
-
84
-
-
72849131815
-
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
-
Eyerich S, Eyerich K, Pennino D, et al. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J Clin Invest 2009; 119:3573-3585.
-
(2009)
J Clin Invest
, vol.119
, pp. 3573-3585
-
-
Eyerich, S.1
Eyerich, K.2
Pennino, D.3
-
85
-
-
76049091500
-
Human Langerhans cells induce distinct IL-22-producing CD4+T cells lacking IL-17 production
-
Fujita H, Nograles KE, Kikuchi T, et al. Human Langerhans cells induce distinct IL-22-producing CD4+T cells lacking IL-17 production. Proc Natl Acad Sci\USA 2009; 106:21795-21800.
-
(2009)
Proc Natl Acad Sci\USA
, vol.106
, pp. 21795-21800
-
-
Fujita, H.1
Nograles, K.E.2
Kikuchi, T.3
-
86
-
-
0034327264
-
T regulatory cells 1 inhibit a Th2-specific response in vivo
-
Cottrez F, Hurst SD, Coffman RL, Groux H. T regulatory cells 1 inhibit a Th2-specific response in vivo. J Immunol 2000; 165:4848-4853.
-
(2000)
J Immunol
, vol.165
, pp. 4848-4853
-
-
Cottrez, F.1
Hurst, S.D.2
Coffman, R.L.3
Groux, H.4
-
87
-
-
33845445488
-
Inhibition of human allergic T-helper type 2 immune responses by induced regulatory T cells requires the combination of interleukin-10-treated dendritic cells and transforming growth factor-beta for their induction
-
Bellinghausen I, Konig B, Bottcher I, et al. Inhibition of human allergic T-helper type 2 immune responses by induced regulatory T cells requires the combination of interleukin-10-treated dendritic cells and transforming growth factor-beta for their induction. Clin Exp Allergy 2006; 36:1546-1555.
-
(2006)
Clin Exp Allergy
, vol.36
, pp. 1546-1555
-
-
Bellinghausen, I.1
Konig, B.2
Bottcher, I.3
-
88
-
-
0032128421
-
Role of interleukin 10 in specific immunotherapy
-
Akdis CA, Blesken T, Akdis M, et al. Role of interleukin 10 in specific immunotherapy. J Clin Invest 1998; 102:98-106.
-
(1998)
J Clin Invest
, vol.102
, pp. 98-106
-
-
Akdis, C.A.1
Blesken, T.2
Akdis, M.3
-
89
-
-
52249095519
-
T-cell regulatory mechanisms in specific immunotherapy
-
Jutel M, Akdis CA. T-cell regulatory mechanisms in specific immunotherapy. Chem Immunol Allergy 2008; 94:158-177.
-
(2008)
Chem Immunol Allergy
, vol.94
, pp. 158-177
-
-
Jutel, M.1
Akdis, C.A.2
-
90
-
-
2942685507
-
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
-
Akdis M, Verhagen J, Taylor A, et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med 2004; 199:1567-1575.
-
(2004)
J Exp Med
, vol.199
, pp. 1567-1575
-
-
Akdis, M.1
Verhagen, J.2
Taylor, A.3
-
91
-
-
58149306013
-
In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure
-
Meiler F, Zumkehr J, Klunker S, et al. In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure. J Exp Med 2008; 205: 2887-2898.
-
(2008)
J Exp Med
, vol.205
, pp. 2887-2898
-
-
Meiler, F.1
Zumkehr, J.2
Klunker, S.3
-
92
-
-
0038363534
-
IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy
-
Jutel M, Akdis M, Budak F, et al. IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol 2003; 33:1205-1214.
-
(2003)
Eur J Immunol
, vol.33
, pp. 1205-1214
-
-
Jutel, M.1
Akdis, M.2
Budak, F.3
-
93
-
-
34247469039
-
IL-10-treated dendritic cells decrease airway hyperresponsiveness and airway inflammation in mice
-
Koya T, Matsuda H, Takeda K, et al. IL-10-treated dendritic cells decrease airway hyperresponsiveness and airway inflammation in mice. J Allergy Clin Immunol 2007; 119:1241-1250.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1241-1250
-
-
Koya, T.1
Matsuda, H.2
Takeda, K.3
-
94
-
-
34250843152
-
IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain-containing protein tyrosine phosphatase 1
-
Taylor A, Akdis M, Joss A, et al. IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain-containing protein tyrosine phosphatase 1. J Allergy Clin Immunol 2007; 120:76-83.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 76-83
-
-
Taylor, A.1
Akdis, M.2
Joss, A.3
-
95
-
-
29544440569
-
Absence of T-regulatory cell expression and function in atopic dermatitis skin
-
Verhagen J, Akdis M, Traidl-Hoffmann C, et al. Absence of T-regulatory cell expression and function in atopic dermatitis skin. J Allergy Clin Immunol 2006; 117:176-183.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 176-183
-
-
Verhagen, J.1
Akdis, M.2
Traidl-Hoffmann, C.3
-
96
-
-
34948846153
-
Orally administered TGF-beta is biologically active in the intestinal mucosa and enhances oral tolerance
-
Ando T, Hatsushika K, Wako M, et al. Orally administered TGF-beta is biologically active in the intestinal mucosa and enhances oral tolerance. J Allergy Clin Immunol 2007; 120:916-923.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 916-923
-
-
Ando, T.1
Hatsushika, K.2
Wako, M.3
-
97
-
-
73349115263
-
Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells
-
Klunker S, Chong MM, Mantel PY, et al. Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells. J Exp Med 2009; 206:2701-2715.
-
(2009)
J Exp Med
, vol.206
, pp. 2701-2715
-
-
Klunker, S.1
Chong, M.M.2
Mantel, P.Y.3
|