CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses

Journal of Immunology

Volumn 184, Issue 2, 2010, Pages 1102-1110

  Carbone, Teresa ^a   Nasorri, Francesca ^a   Pennino, Davide ^a   Eyerich, Kilian ^b   Foerster, Stefanie ^b   Cifaldi, Loredana ^a   Traidl Hoffman, Claudia ^b   Behrendt, Heidrun ^b   Cavani, Andrea ^a  

^a LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CD56 ANTIGEN; CD69 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR3; CYTOKINE; GAMMA INTERFERON; HAPTEN; INTERLEUKIN 2; L SELECTIN; METAL; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3; NATURAL KILLER CELL RECEPTOR NKG2A; NATURAL KILLER CELL RECEPTOR NKG2D; PERFORIN; CHEMOKINE RECEPTOR; FC RECEPTOR;

ADAPTIVE IMMUNITY; ALLERGIC REACTION; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CYTOKINE RELEASE; DERMIS; EPIDERMIS; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; KERATINOCYTE; NATURAL KILLER CELL; NICKEL HYPERSENSITIVITY; PRIORITY JOURNAL; SKIN ALLERGY; UPREGULATION; CHEMOTAXIS; IMMUNOLOGY; INNATE IMMUNITY; PATHOLOGY; SECRETION;

ADAPTIVE IMMUNITY; ANTIGENS, CD56; APOPTOSIS; CHEMOTAXIS; CYTOKINES; DERMATITIS, ALLERGIC CONTACT; HAPTENS; HUMANS; IMMUNITY, INNATE; KERATINOCYTES; KILLER CELLS, NATURAL; L-SELECTIN; RECEPTORS, CHEMOKINE; RECEPTORS, IGG;

EID: 76249118744     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902518     Document Type: Article

References (34)

1. Cavani, A., O. De Pità, and G. Girolomoni. 2007. New aspects of the molecular basis of contact allergy. Curr. Opin. Allergy Clin. Immunol. 7: 404-408.
2. Nosbaum, A., M. Vocanson, A. Rozieres, A. Hennino, and J. F. Nicolas. 2009. Allergic and irritant contact dermatitis. Eur. J. Dermatol. 19: 325-332.
3. Akiba, H., J. Kehren, M. T. Ducluzeau, M. Krasteva, F. Horand, D. Kaiserlian, F. Kaneko, and J. F. Nicolas. 2002. Skin inflammation during contact hypersensitivity is mediated by early recruitment of CD8+ T cytotoxic 1 cells inducing keratinocyte apoptosis. J. Immunol. 168: 3079-3087. (Pubitemid 34211691)
4. Traidl, C., S. Sebastiani, C. Albanesi, H. F. Merk, P. Puddu, G. Girolomoni, and A. Cavani. 2000. Disparate cytotoxic activity of nickel-specific CD8+ and CD4+ T cell subsets against keratinocytes. J. Immunol. 165: 3058-3064.
5. Trautmann, A., F. Altznauer, M. Akdis, H. U. Simon, R. Disch, E. B. Bröcker, K. Blaser, and C. A. Akdis. 2001. The differential fate of cadherins during Tcell-induced keratinocyte apoptosis leads to spongiosis in eczematous dermatitis. J. Invest. Dermatol. 117: 927-934.
6. Trautmann, A., M. Akdis, D. Kleemann, F. Altznauer, H. U. Simon, T. Graeve, M. Noll, E. B. Bröcker, K. Blaser, and C. A. Akdis. 2000. T cell-mediated Fasinduced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis. J. Clin. Invest. 106: 25-35.
7. Albanesi, C., C. Scarponi, S. Sebastiani, A. Cavani, M. Federici, S. Sozzani, and G. Girolomoni. 2001. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases. J. Leukoc. Biol. 70: 617-623.
8. Meller, S., A. I. Lauerma, F. M. Kopp, F. Winterberg, M. Anthoni, A. Müller, M. Gombert, A. Haahtela, H. Alenius, J. Rieker, et al. 2007. Chemokine responses distinguish chemical-induced allergic from irritant skin inflammation: memory T cells make the difference. J. Allergy Clin. Immunol. 119: 1470-1480.
9. Sebastiani, S., C. Albanesi, P. O. De, P. Puddu, A. Cavani, and G. Girolomoni. 2002. The role of chemokines in allergic contact dermatitis. Arch. Dermatol. Res. 293: 552-559.
10. Albanesi, C., C. Scarponi, S. Sebastiani, A. Cavani, M. Federici, O. De Pità, P. Puddu, and G. Girolomoni. 2000. IL-4 enhances keratinocyte expression of CXCR3 agonistic chemokines. J. Immunol. 165: 1395-1402. (Pubitemid 30604571)
11. Harvell, J. D., M. Nowfar-Rad, and U. Sundram. 2003. An immunohistochemical study of CD4, CD8, TIA-1 and CD56 subsets in inflammatory skin disease. J. Cutan. Pathol. 30: 108-113.
12. Bangert, C., J. Friedl, G. Stary, G. Stingl, and T. Kopp. 2003. Immunopathologic features of allergic contact dermatitis in humans: participation of plasmacytoid dendritic cells in the pathogenesis of the disease? J. Invest. Dermatol. 121: 1409-1418.
13. Gober, M. D., R. Fishelevich, Y. Zhao, D. Unutmaz, and A. A. Gaspari. 2008. Human natural killer T cells infiltrate into the skin at elicitation sites of allergic contact dermatitis. J. Invest. Dermatol. 128: 1460-1469.
14. Eyerich, K., J. Huss-Marp, U. Darsow, A. Wollenberg, S. Foerster, J. Ring, H. Behrendt, and C. Traidl-Hoffmann. 2008. Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients. Int. Arch. Allergy Immunol. 145: 213-223.
15. Lanier, L. L. 2005. NK cell recognition. Annu. Rev. Immunol. 23: 225-274.
16. Moretta, A., C. Bottino, M. Vitale, D. Pende, C. Cantoni, M. C. Mingari, R. Biassoni, and L. Moretta. 2001. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19: 197-223.
17. Di Santo, J. P. 2008. Functionally distinct NK-cell subsets: developmental origins and biological implications. Eur. J. Immunol. 38: 2948-2951.
18. Moretta, A., E. Marcenaro, S. Parolini, G. Ferlazzo, and L. Moretta. 2008. NK cells at the interface between innate and adaptive immunity. Cell Death Differ. 15: 226-233.
19. Poli, A., T. Michel, M. Thérésine, E. Andrès, F. Hentges, and J. Zimmer. 2009. CD56bright natural killer (NK) cells: an important NK cell subset. Immunology 126: 458-465.
20. Jacobs, R., G. Hintzen, A. Kemper, K. Beul, S. Kempf, G. Behrens, K.W. Sykora, and R. E. Schmidt. 2001. CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells. Eur. J. Immunol. 31: 3121-3127.
21. Fraticelli, P.,M. Sironi, G. Bianchi, D. D'Ambrosio, C. Albanesi, A. Stoppacciaro, M. Chieppa, P. Allavena, L. Ruco, G. Girolomoni, et al. 2001. Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses. J. Clin. Invest. 107: 1173-1181.
22. Frey,M., N. B. Packianathan, T. A. Fehniger, M. E. Ross,W. C.Wang, C. C. Stewart, M. A. Caligiuri, and S. S. Evans. 1998. Differential expression and function of L-selectin on CD56bright and CD56dim natural killer cell subsets. J. Immunol. 161: 400-408.
23. Campbell, J. J., S. Qin, D. Unutmaz, D. Soler, K. E. Murphy, M. R. Hodge, L. Wu, and E. C. Butcher. 2001. Unique subpopulations of CD56+ NK and NKT peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J. Immunol. 166: 6477-6482.
24. Berahovich, R. D., N. L. Lai, Z. Wei, L. L. Lanier, and T. J. Schall. 2006. Evidence for NK cell subsets based on chemokine receptor expression. J. Immunol. 177: 7833-7840. (Pubitemid 44846299)
25. Sentman, C. L., S. K. Meadows, C. R. Wira, and M. Eriksson. 2004. Recruitment of uterine NK cells: induction of CXC chemokine ligands 10 and 11 in human endometrium by estradiol and progesterone. J. Immunol. 173: 6760-6766.
26. Carlino, C., H. Stabile, S. Morrone, R. Bulla, A. Soriani, C. Agostinis, F. Bossi, C. Mocci, F. Sarazani, F. Tedesco, et al. 2008. Recruitment of circulating NK cells through decidual tissues: a possible mechanism controlling NK cell accumulation in the uterus during early pregnancy. Blood 111: 3108-3115.
27. Ottaviani, C., F. Nasorri, C. Bedini, O. de Pità, G. Girolomoni, and A. Cavani. 2006. CD56brightCD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation. Eur. J. Immunol. 36: 118-128.
28. Parolini, S., A. Santoro, E. Marcenaro, W. Luini, L. Massardi, F. Facchetti, D. Communi, M. Parmentier, A. Majorana, M. Sironi, et al. 2007. The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues. Blood 109: 3625-3632.
29. O'Leary, J. G., M. Goodarzi, D. L. Drayton, and U. H. von Andrian. 2006. T cell- and B cell-independent adaptive immunity mediated by natural killer cells. Nat. Immunol. 7: 507-516.
30. Cavani, A., F. Nasorri, C. Prezzi, S. Sebastiani, C. Albanesi, and G. Girolomoni. 2000. Human CD4+ T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses. J. Invest. Dermatol. 114: 295-302.
31. Nasorri, F., S. Sebastiani, V. Mariani, O. De Pità, P. Puddu, G. Girolomoni, and A. Cavani. 2002. Activation of nickel-specific CD4+ T lymphocytes in the absence of professional antigen-presenting cells. J. Invest. Dermatol. 118: 172-179.
32. Marcenaro, E., M. Della Chiesa, S. Pesce, S. Agaugué, and A. Moretta. 2009. The NK/DC complot. Adv. Exp. Med. Biol. 633: 7-16.
33. Cella, M., A. Fuchs,W. Vermi, F. Facchetti, K. Otero, J.K. Lennerz, J. M. Doherty, J. C. Mills, and M. Colonna. 2009. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 457: 722-725.
34. Sun, J. C., J. N. Beilke, and L. L. Lanier. 2009. Adaptive immune features of natural killer cells. Nature 457: 557-561.