Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients

FASEB Journal

Volumn 12, Issue 14, 1998, Pages 1559-1569

  Natter, Susanne ^a   Seiberler, Susanne ^a   Hufnagl, Peter ^a   Binder, Bernd R ^a   Hirschl, Alexander M ^a   Ring, Johannes ^b   Abeck, Dietrich ^b   Schmidt, Tanja ^b   Valent, Peter ^a   Valenta, Rudolf ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

CDNA; Cloning; Expression in Escherichia coli; IgE autoimmunity

Indexed keywords

AUTOANTIGEN; COMPLEMENTARY DNA; IMMUNOGLOBULIN E;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ANTIGEN PRESENTING CELL; ARTICLE; ATOPIC DERMATITIS; AUTOIMMUNITY; DNA DETERMINATION; DNA LIBRARY; DNA SEQUENCE; EPITHELIUM CELL; ESCHERICHIA COLI; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL;

ARA; ESCHERICHIA COLI;

EID: 0031764786     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.12.14.1559     Document Type: Article

References (48)

1. Casolaro, V., Georas S. N., Song, Z., and Ono, S. J. (1996) Biology and genetics of atopic disease. Curr. Opin. Immunol. 8, 796-803
2. Hopkin, J. M. (1997) Mechanisms of enhanced prevalence of asthma and atopy in developed countries. Curr. Opin. Immunol. 9, 788-792
3. Ishizaka, K., Ishizaka, T., and Hornbrook, M. M. (1966) Physicochemical properties of reaginic antibody IV. Presence of a unique immunoglobulin as a carrier of reaginic activity. J. Immunol. 97, 75-86
4. Lichtenstein, L. M., and Osler, A. G. (1964) Studies on the mechanisms of hypersensitivity phenomena. IX. Histamine release from human leucocytes by ragweed pollen antigen. J. Exp. Med. 120, 507-530
5. Segal, D. M., Taurog, J. D., and Metzger, H. (1977) Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation. Proc. Natl. Acad. Sci. USA 41, 457-467
6. Leung, D. Y. M. (1993) Role of IgE in atopic dermatitis, Curr. Opin. Immunol. 5, 956-962
7. Hanifin, J. M., Cooper, K. D., and Roth, H. L. (1986) Atopy and atopic dermatitis. J. Am. Acad. Dermatol. 15, 703-706
8. Leung, D. Y. M., Rhodes, A. R., Geha, R. S., Schneider, L. C., and Ring, J. (1993) Atopic dermatitis, atopic eczema. In Dermatology in General Medicine (Fitzpatrick, T. B., Eisen, A. Z., Wolff, K., Freedberg, I. M., and Austen, K. F., eds) 4th Ed, p. 1543, McGraw-Hill, New York
9. Ruzicka, T., Ring, J., and Przybilla, B., eds (1991) Handbook of Atopic Eczema, Springer, Berlin
10. Cooper, K. D. (1989) Mechanisms of atopic dermatitis. In Immune Mechanisms in Cutaneous Disease (Norris, D. A., ed) p. 247, Marcel Dekker, New York
11. Sampson, H. A. (1990) Pathogenesis of eczema. Clin. Exp. Allergy 20, 459-467
12. Mudde, G. C., Van Reijsen, F. G., Boland, G. J., de Gast, G. C., Bruijnzeel, P. L., and Bruijnzeel Koomen, C. A. (1990) Allergen presentation by epidermal Langerhans cells from patients with atopic dermatitis is mediated by IgE. Immunology 69, 335-341
13. Maurer, D., Ebner, C., Reininger, B., Fiebiger, E., Kraft, D., Kinet,J. P., and Stingl, G. (1995) The high affinity IgE receptor (FcεRI) mediates IgE-dependent allergen presentation. J. Immunol. 154, 6285-6290
14. Maurer, D., Fiebiger, E., Ebner, C., Reininger, B., Fischer, G. F., Wichlas, S., Jouvin, M. H., Schmitt-Egenolf, M., Kraft, D., Kinet, J. P., and Stingl, G. (1996) Peripheral blood dendritic cells express FcεRI as a complex composed of FcεRIα-and FcεRIγ-chains and can use this receptor for IgE-mediated allergen presentation. J. Immunol. 157, 607-616
15. Valenta, R., and Kraft, D. (1995) Recombinant allergens for diagnosis and therapy of allergic diseases. Curr. Opin. Immunol. 7, 751-756
16. Cooper, K, D. (1994) Atopic dermatitis: recent trends in pathogenesis and therapy. J. Invest. Dermatol. 102, 128-137
17. Ring, J., Brockow, K., and Abeck, D. (1996) The therapeutic concept of 'patient management' in atopic eczema. Allergy 51, 206-215
18. Herz, U., Bunikowski, R., and Renz, H. (1998) The role of T cells in atopic dermatitis-new aspects on the dynamics of cytokine production and the contribution of bacterial superantigens. Int. Arch. Allergy Immunol. 115, 179-190
19. Berrens, L. (1970) The allergens in house dust. Prog. Allergy 14, 259-266
20. Simon, F. A. (1947) The allergen of human dander present in the skin of the general body surface. J. Invest. Dermatol. 9, 329-332
21. Hampton, S. F., and Cooke, R. A. (1941) The sensitivity of man to human dander, with particular reference to eczema (allergic dermatitis). J. Allergy 13, 63-76
22. Simon, F. A. (1944) On the allergen in human dander. J. Allergy 15, 338-345
23. Valenta, R., Duchênc, M., Pettenburger, K., Sillaber, C., Valent, P., Bettelheim, P., Breitenbach, M., Rumpold, H., Kraft, D., and Scheiner, O. (1991) Identification of profilin as a novel allergen: IgE autoreactivity in sensitized individuals. Science 253, 557-560
24. Valenta, R., Ferreira, F., Grote, M., Swoboda, I., Vrtala, S., Duchêne, M., Deviller, P., Meagher, R. B., McKinney, E., HeberleBors, E., Kraft, D., and Scheiner, O. (1993) Identification of profilin as an actin-binding protein in higher plants. J. Biol. Chem. 268, 22777-22781
25. Staiger, C. J.,Yuan, M., Valenta, R., Shaw, P. J., Warn, R. M., and Lloyd, C. W. (1994) Microinjected profilin affects cytoplasmic streaming in plant cells by rapidly depolymerizing actin microfilaments. Curr. Biol. 4, 215-219
26. Giehl, K., Valenta, R., Rothkegel, M., Ronsiek, M., Mannherz H. G., and Jockusch, B. (1994) Biochemical characterization of plant and animal profilins: the interaction of plant profilin with mammalian actin. Eur.J. Biochem. 226, 681-689
27. Spitzauer, S., Schweiger, C., Sperr, W. R., Pandjaitan, B., Valent, P., Mühl, S., Ebner, C., Scheiner, O., Kraft, D., Rumpold, H., and Valenta, R. (1994) Molecular characterization of dog albumin as a cross-reactive allergen. J. Allergy Clin. Immunol. 93, 614-627
28. Crameri, R., Faith, A., Hemmann, S., Jaussi, R., Ismail, C., Menz, G., and Blaser, K. (1996) Humoral and cell-mediated autoimmunity in allergy to Aspergillus fumigatus. J. Exp. Med. 184, 265-270
29. Valenta, R., Maurer, D., Steiner, R., Seiberler, S., Sperr, W. R., Valent, P., Spitzauer, S., Kapiotis, S., Smolen, J., and Stingl, G. (1996) Immunoglobulin E response to human proteins in atopic patients. J. Invest. Dermatol. 107, 203-208
30. Wiedmann, B., Sakai, H., Davis, T. A., and Wiedmann, M. (1994) A protein complex required for signal-sequence-specific sorting and translocation. Nature (London) 370, 434-440
31. Lersch, R., and Fuchs, E. (1988) Sequence and expression of a type II keratin. K5, in human epidermal cells. Mol. Cell. Biol. 8, 486-493
32. Glass, C., Kim, K. H., and Fuchs, E. (1985) Sequence and expression of a human type II mesothelial keratin. J. Cell Biol. 101, 2366-2373
33. Tyncr, A. L., Eichman, M. J., and Fuchs, E. (1985) The sequence of a type II keratin gene expressed in human skin: conservation of structure among all intermediate filament genes. Proc. Natl. Acad. Sci. USA 82, 4683-4687
34. Zani, V. J., Asou, N., Jadayel, D., Heward, J. M., Shipley, J., Nacheva, E., Takasuki, K., Catovsky, D., and Dyer, M. J. (1996) Molecular cloning of complex chromosomal translocation t (8;14;12) (q24.1; q32.3; q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon. Blood 87, 3124-3134
35. Hanifin, J. M., and Rajka, G. (1980) Diagnostic features of atopic dermatitis. Acta Dermatovener (Stockholm) Suppl. 92, 44-47
36. Huynh, T. V., Young, R. A., and Davis, R. W. (1985) Construction and screening of cDNA libraries in λgtlO and λgt11. In cDNA Cloning. A Practical Approach (Glover, D. M., ed) Vol. 1, p. 49, IRL Press, Oxford, U.K.
37. Jaffe, E, A., Nachman, R. L., Becker, C. G., and Minik, C. R. (1973) Culture of human endothelial cells derived from umbilical veins. J. Clin. Invest. 52, 2745-2751
38. Vrtala, S., Grote, M., Duchêne, M., vanRee, R., Kraft, D., Scheiner, O., and Valenta, R. (1993) Properties of tree and grass pollen allergens, reinvestigation of the linkage between solubility and allergenicity. Int. Arch. Allergy Immunol. 102, 160-169
39. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227, 680-685
40. Towbin, H., Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354
41. Valenta, R., Duchêne, M., Ebner, C., Valent, P., Sillaber, C., Deviller, P., Ferreira, F., Tejkl, M., Edelmann, H., Kraft, D., and Scheiner, O. (1992) Profilins constitute a novel family of functional plant pan-allergens. J. Exp. Med. 175, 377-385
42. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (1988) Current Protocols in Molecular Biology, Green Publishing Associates and Wiley-Interscience, New York
43. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) DNAsequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-6467
44. Davis, L. G., Dibner, M. D., and Battey, J. F. (1986) Basic Methods in Molecular Biology, Elsevier, New York
45. Feinberg, A. P., and Vogelstein, B. (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132, 6-13
46. Valenta, R., Vrtala, S., Ebner, C., Kraft, D., and Scheiner, O. (1992) Diagnosis of grass pollen allergy with recombinant timothy grass (Phleum pratense) pollen allergens. Int. Arch. Allergy Immunol. 97, 287-294
47. Vrtala, S., Hirtenlehner, K., Vangelista, L., Pastore, A., Eichler, H. G., Sperr, W. R., Valent, P., Ebner, C., Kraft, D., and Valenta, R. (1997) Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments, candidates for a novel form of specific immunotherapy. J. Clin. Invest. 99, 1673-1681
48. Breiteneder, H., Pettenburger, K., Bito, A., Valenta, R., Kraft, D., Rumpold, H., Scheiner, O., and Breitenbach, M. (1989) The gene coding for the major birch pollen allergen, Bet v 1, is highly homologous to a pea disease resistance response gene. EMBO J. 8, 1935-1938