메뉴 건너뛰기




Volumn 188, Issue 2, 2010, Pages 309-318

Molecular mechanisms of asbestos-induced lung epithelial cell apoptosis

Author keywords

Alveolar epithelial cell; Apoptosis; Asbestos; Free radicals; Mitochondria; P53

Indexed keywords

8 OXOGUANINE DNA GLYCOSYLASE; ACONITATE HYDRATASE; APOPTOSIS SIGNAL REGULATING KINASE 1; ASBESTOS; BH3 PROTEIN; CASPASE 9; CELL DNA; CHAPERONE; CYTOCHROME C; DNA GLYCOSYLTRANSFERASE; ENDOPEPTIDASE LA; FRATAXIN; MITOCHONDRIAL DNA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTEIN ALPHA OGG1; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BETA OGG1; PROTEIN KINASE C DELTA; PROTEIN NOXA; PROTEIN OGG1; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SIGMA 1 OPIATE RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CARCINOGEN;

EID: 77956179509     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.03.047     Document Type: Review
Times cited : (71)

References (124)
  • 1
    • 0020477738 scopus 로고
    • The pathology of asbestos-associated diseases of the lungs and pleural cavities: diagnostic criteria and proposed grading schema. Report of the Pneumoconiosis Committee of the College of American Pathologists and the National Institute for Occupational Safety and Health
    • Craighead J.E., Abraham J.L., Churg A., Green F.H., Kleinerman J., Pratt P.C., Seemayer T.A., Vallyathan V., Weill H. The pathology of asbestos-associated diseases of the lungs and pleural cavities: diagnostic criteria and proposed grading schema. Report of the Pneumoconiosis Committee of the College of American Pathologists and the National Institute for Occupational Safety and Health. Arch. Pathol. Lab. Med. 1982, 106(11):544-596.
    • (1982) Arch. Pathol. Lab. Med. , vol.106 , Issue.11 , pp. 544-596
    • Craighead, J.E.1    Abraham, J.L.2    Churg, A.3    Green, F.H.4    Kleinerman, J.5    Pratt, P.C.6    Seemayer, T.A.7    Vallyathan, V.8    Weill, H.9
  • 2
    • 0025156969 scopus 로고
    • Asbestos: scientific developments and implications for public policy
    • Mossman B.T., Bignon J., Corn M., Seaton A., Gee J.B.L. Asbestos: scientific developments and implications for public policy. Science 1990, 247(4940):294-301.
    • (1990) Science , vol.247 , Issue.4940 , pp. 294-301
    • Mossman, B.T.1    Bignon, J.2    Corn, M.3    Seaton, A.4    Gee, J.B.L.5
  • 3
    • 0026078961 scopus 로고
    • Cellular and molecular basis of the asbestos-related diseases
    • Rom W.N., Travis W.D., Brody A.R. Cellular and molecular basis of the asbestos-related diseases. Am. Rev. Respir. Dis. 1991, 143(2):408-422.
    • (1991) Am. Rev. Respir. Dis. , vol.143 , Issue.2 , pp. 408-422
    • Rom, W.N.1    Travis, W.D.2    Brody, A.R.3
  • 5
    • 0031799746 scopus 로고    scopus 로고
    • Mechanisms in the pathogenesis of asbestosis and silicosis
    • Mossman B.T., Churg A. Mechanisms in the pathogenesis of asbestosis and silicosis. Am. J. Respir. Crit. Care Med. 1998, 157(5 Pt 1):1666-1680.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , Issue.5 PART 1 , pp. 1666-1680
    • Mossman, B.T.1    Churg, A.2
  • 6
    • 0033057603 scopus 로고    scopus 로고
    • The molecular basis of asbestos induced lung injury
    • Kamp D.W., Weitzman S.A. The molecular basis of asbestos induced lung injury. Thorax 1999, 54(7):638-652.
    • (1999) Thorax , vol.54 , Issue.7 , pp. 638-652
    • Kamp, D.W.1    Weitzman, S.A.2
  • 7
    • 62349106819 scopus 로고    scopus 로고
    • Asbestos-induced lung diseases: an update
    • Kamp D.W. Asbestos-induced lung diseases: an update. Transl. Res. 2009, 153(4):143-152.
    • (2009) Transl. Res. , vol.153 , Issue.4 , pp. 143-152
    • Kamp, D.W.1
  • 8
    • 0029908521 scopus 로고    scopus 로고
    • The uptake of mineral particles by pulmonary epithelial cells
    • Churg A. The uptake of mineral particles by pulmonary epithelial cells. Am. J. Respir. Crit. Care Med. 1996, 154(4 Pt 1):1124-1140.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154 , Issue.4 PART 1 , pp. 1124-1140
    • Churg, A.1
  • 9
    • 29044433108 scopus 로고    scopus 로고
    • Role of alphavbeta5 integrin receptor in endocytosis of crocidolite and its effect on intracellular glutathione levels in human lung epithelial (A549) cells
    • Pande P., Mosleh T.A., Aust A.E. Role of alphavbeta5 integrin receptor in endocytosis of crocidolite and its effect on intracellular glutathione levels in human lung epithelial (A549) cells. Toxicol. Appl. Pharmacol. 2006, 210(1-2):70-77.
    • (2006) Toxicol. Appl. Pharmacol. , vol.210 , Issue.1-2 , pp. 70-77
    • Pande, P.1    Mosleh, T.A.2    Aust, A.E.3
  • 10
    • 0028817510 scopus 로고
    • The effect of iron binding on the ability of crocidolite asbestos to catalyze DNA single-strand breaks
    • Hardy J.A., Aust A.E. The effect of iron binding on the ability of crocidolite asbestos to catalyze DNA single-strand breaks. Carcinogenesis 1995, 16(2):319-325.
    • (1995) Carcinogenesis , vol.16 , Issue.2 , pp. 319-325
    • Hardy, J.A.1    Aust, A.E.2
  • 11
    • 0031217594 scopus 로고    scopus 로고
    • Mechanisms of fiber-induced genotoxicity
    • Jaurand M.C. Mechanisms of fiber-induced genotoxicity. Environ. Health Perspect. 1997, 105(Suppl. 5):1073-1084.
    • (1997) Environ. Health Perspect. , vol.105 , Issue.SUPPL. 5 , pp. 1073-1084
    • Jaurand, M.C.1
  • 13
    • 57149117863 scopus 로고    scopus 로고
    • Epithelial fibroblast triggering and interactions in pulmonary fibrosis
    • Noble P.W. Epithelial fibroblast triggering and interactions in pulmonary fibrosis. Eur. Respir. Rev. 2008, 17(109):123-129.
    • (2008) Eur. Respir. Rev. , vol.17 , Issue.109 , pp. 123-129
    • Noble, P.W.1
  • 14
    • 0024571324 scopus 로고
    • Incorporation of tritiated thymidine by epithelial and interstitial cells in bronchiolar-alveolar regions of asbestos-exposed rats
    • Brody A.R., Overby L.H. Incorporation of tritiated thymidine by epithelial and interstitial cells in bronchiolar-alveolar regions of asbestos-exposed rats. Am. J. Pathol. 1989, 134(1):133-140.
    • (1989) Am. J. Pathol. , vol.134 , Issue.1 , pp. 133-140
    • Brody, A.R.1    Overby, L.H.2
  • 15
    • 4444232909 scopus 로고    scopus 로고
    • Diagnosis and initial management of nonmalignant diseases related to asbestos
    • American Thoracic Society
    • American Thoracic Society Diagnosis and initial management of nonmalignant diseases related to asbestos. Am. J. Respir. Crit. Care Med. 2004, 170(6):691-715.
    • (2004) Am. J. Respir. Crit. Care Med. , vol.170 , Issue.6 , pp. 691-715
  • 16
    • 0025617567 scopus 로고
    • Alveolar type II cell responses to chronic inhalation of chrysotile asbestos in rats
    • Pinkerton K.E., Young S.L., Fram E.K., Crapo J.D. Alveolar type II cell responses to chronic inhalation of chrysotile asbestos in rats. Am. J. Respir. Cell Mol. Biol. 1990, 3(6):543-552.
    • (1990) Am. J. Respir. Cell Mol. Biol. , vol.3 , Issue.6 , pp. 543-552
    • Pinkerton, K.E.1    Young, S.L.2    Fram, E.K.3    Crapo, J.D.4
  • 17
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer G., Galluzzi L., Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 2007, 87(1):99-163.
    • (2007) Physiol. Rev. , vol.87 , Issue.1 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 18
    • 57049117856 scopus 로고    scopus 로고
    • Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
    • Kim I., Xu W., Reed J.C. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat. Rev. Drug Discov. 2008, 7(12):1013-1030.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , Issue.12 , pp. 1013-1030
    • Kim, I.1    Xu, W.2    Reed, J.C.3
  • 19
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: opposing activities that mediate cell death
    • Youle R.J., Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 2008, 9(1):47-59.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , Issue.1 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 20
    • 61649104568 scopus 로고    scopus 로고
    • Environmental toxicity, oxidative stress and apoptosis: menage a trois
    • Franco R., Sanchez-Olea R., Reyes-Reyes E.M., Panayiotidis M.I. Environmental toxicity, oxidative stress and apoptosis: menage a trois. Mutat. Res. 2009, 674(1-2):3-22.
    • (2009) Mutat. Res. , vol.674 , Issue.1-2 , pp. 3-22
    • Franco, R.1    Sanchez-Olea, R.2    Reyes-Reyes, E.M.3    Panayiotidis, M.I.4
  • 21
    • 0028969940 scopus 로고
    • Asbestos causes DNA strand breaks in cultured pulmonary epithelial cells: role of iron-catalyzed free radicals
    • Kamp D.W., Israbian V.A., Preusen S.E., Zhang C.X., Weitzman S.A. Asbestos causes DNA strand breaks in cultured pulmonary epithelial cells: role of iron-catalyzed free radicals. Am. J. Physiol. 1995, 268(3 Pt 1):L471-480.
    • (1995) Am. J. Physiol. , vol.268 , Issue.3 PART 1
    • Kamp, D.W.1    Israbian, V.A.2    Preusen, S.E.3    Zhang, C.X.4    Weitzman, S.A.5
  • 22
    • 0035337960 scopus 로고    scopus 로고
    • Asbestos causes apoptosis in alveolar epithelial cells: role of iron-induced free radicals
    • Aljandali A., Pollack H., Yeldandi A., Li Y., Weitzman S.A., Kamp D.W. Asbestos causes apoptosis in alveolar epithelial cells: role of iron-induced free radicals. J. Lab. Clin. Med. 2001, 137(5):330-339.
    • (2001) J. Lab. Clin. Med. , vol.137 , Issue.5 , pp. 330-339
    • Aljandali, A.1    Pollack, H.2    Yeldandi, A.3    Li, Y.4    Weitzman, S.A.5    Kamp, D.W.6
  • 23
    • 0037308538 scopus 로고    scopus 로고
    • The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis
    • Panduri V., Weitzman S.A., Chandel N., Kamp D.W. The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis. Am. J. Respir. Cell Mol. Biol. 2003, 28(2):241-248.
    • (2003) Am. J. Respir. Cell Mol. Biol. , vol.28 , Issue.2 , pp. 241-248
    • Panduri, V.1    Weitzman, S.A.2    Chandel, N.3    Kamp, D.W.4
  • 24
    • 2442656662 scopus 로고    scopus 로고
    • Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis
    • Panduri V., Weitzman S.A., Chandel N.S., Kamp D.W. Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis. Am. J. Physiol. Lung Cell Mol. Physiol. 2004, 286(6):L1220-L1227.
    • (2004) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.286 , Issue.6
    • Panduri, V.1    Weitzman, S.A.2    Chandel, N.S.3    Kamp, D.W.4
  • 28
    • 0345707635 scopus 로고    scopus 로고
    • Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice
    • Li X., Rayford H., Uhal B.D. Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice. Am. J. Pathol. 2003, 163(6):2523-2530.
    • (2003) Am. J. Pathol. , vol.163 , Issue.6 , pp. 2523-2530
    • Li, X.1    Rayford, H.2    Uhal, B.D.3
  • 32
    • 0021333972 scopus 로고
    • Asbestos catalyzes hydroxyl and superoxide radical generation from hydrogen peroxide
    • Weitzman S.A., Graceffa P. Asbestos catalyzes hydroxyl and superoxide radical generation from hydrogen peroxide. Arch. Biochem. Biophys. 1984, 228(1):373-376.
    • (1984) Arch. Biochem. Biophys. , vol.228 , Issue.1 , pp. 373-376
    • Weitzman, S.A.1    Graceffa, P.2
  • 35
    • 0025296866 scopus 로고
    • Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis
    • Mossman B.T., Marsh J.P., Sesko A., Hill S., Shatos M.A., Doherty J., Petruska J., Adler K.B., Hemenway D., Mickey R., et al. Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis. Am. Rev. Respir. Dis. 1990, 141(5 Pt 1):1266-1271.
    • (1990) Am. Rev. Respir. Dis. , vol.141 , Issue.5 PART 1 , pp. 1266-1271
    • Mossman, B.T.1    Marsh, J.P.2    Sesko, A.3    Hill, S.4    Shatos, M.A.5    Doherty, J.6    Petruska, J.7    Adler, K.B.8    Hemenway, D.9    Mickey, R.10
  • 36
    • 0025163754 scopus 로고
    • Cytotoxicity of long and short crocidolite asbestos fibers in vitro and in vivo
    • Goodglick L.A., Kane A.B. Cytotoxicity of long and short crocidolite asbestos fibers in vitro and in vivo. Cancer Res. 1990, 50(16):5153-5163.
    • (1990) Cancer Res. , vol.50 , Issue.16 , pp. 5153-5163
    • Goodglick, L.A.1    Kane, A.B.2
  • 37
    • 0025027088 scopus 로고
    • Active oxygen species mediate asbestos fiber uptake by tracheal epithelial cells
    • Hobson J., Wright J.L., Churg A. Active oxygen species mediate asbestos fiber uptake by tracheal epithelial cells. FASEB J. 1990, 4(13):3135-3139.
    • (1990) FASEB J. , vol.4 , Issue.13 , pp. 3135-3139
    • Hobson, J.1    Wright, J.L.2    Churg, A.3
  • 38
    • 0029621132 scopus 로고
    • Phytic acid, an iron chelator, attenuates pulmonary inflammation and fibrosis in rats after intratracheal instillation of asbestos
    • Kamp D.W., Israbian V.A., Yeldandi A.V., Panos R.J., Graceffa P., Weitzman S.A. Phytic acid, an iron chelator, attenuates pulmonary inflammation and fibrosis in rats after intratracheal instillation of asbestos. Toxicol. Pathol. 1995, 23(6):689-695.
    • (1995) Toxicol. Pathol. , vol.23 , Issue.6 , pp. 689-695
    • Kamp, D.W.1    Israbian, V.A.2    Yeldandi, A.V.3    Panos, R.J.4    Graceffa, P.5    Weitzman, S.A.6
  • 39
    • 31644437328 scopus 로고    scopus 로고
    • Increased sensitivity to asbestos-induced lung injury in mice lacking extracellular superoxide dismutase
    • Fattman C.L., Tan R.J., Tobolewski J.M., Oury T.D. Increased sensitivity to asbestos-induced lung injury in mice lacking extracellular superoxide dismutase. Free Radic. Biol. Med. 2006, 40(4):601-607.
    • (2006) Free Radic. Biol. Med. , vol.40 , Issue.4 , pp. 601-607
    • Fattman, C.L.1    Tan, R.J.2    Tobolewski, J.M.3    Oury, T.D.4
  • 40
    • 0037828891 scopus 로고    scopus 로고
    • Asbestos-induced pulmonary toxicity: role of DNA damage and apoptosis
    • Upadhyay D., Kamp D.W. Asbestos-induced pulmonary toxicity: role of DNA damage and apoptosis. Exp. Biol. Med. (Maywood) 2003, 228(6):650-659.
    • (2003) Exp. Biol. Med. (Maywood) , vol.228 , Issue.6 , pp. 650-659
    • Upadhyay, D.1    Kamp, D.W.2
  • 41
    • 0023635663 scopus 로고
    • The role of catalytic iron in asbestos induced lipid peroxidation and DNA-strand breakage in C3H10T1/2 cells
    • Turver C.J., Brown R.C. The role of catalytic iron in asbestos induced lipid peroxidation and DNA-strand breakage in C3H10T1/2 cells. Br. J. Cancer 1987, 56(2):133-136.
    • (1987) Br. J. Cancer , vol.56 , Issue.2 , pp. 133-136
    • Turver, C.J.1    Brown, R.C.2
  • 42
    • 0024469131 scopus 로고
    • Induction of DNA strand breaks in cultured rat embryo cells by crocidolite asbestos as assessed by nick translation
    • Libbus B.L., Illenye S.A., Craighead J.E. Induction of DNA strand breaks in cultured rat embryo cells by crocidolite asbestos as assessed by nick translation. Cancer Res. 1989, 49(20):5713-5718.
    • (1989) Cancer Res. , vol.49 , Issue.20 , pp. 5713-5718
    • Libbus, B.L.1    Illenye, S.A.2    Craighead, J.E.3
  • 43
    • 0030756155 scopus 로고    scopus 로고
    • Cell cycle response to DNA damage differs in bronchial epithelial cells and lung fibroblasts
    • Gadbois D.M., Lehnert B.E. Cell cycle response to DNA damage differs in bronchial epithelial cells and lung fibroblasts. Cancer Res. 1997, 57(15):3174-3179.
    • (1997) Cancer Res. , vol.57 , Issue.15 , pp. 3174-3179
    • Gadbois, D.M.1    Lehnert, B.E.2
  • 44
    • 0031417106 scopus 로고    scopus 로고
    • Patterns of 8-hydroxydeoxyguanosine formation in DNA and indications of oxidative stress in rat and human pleural mesothelial cells after exposure to crocidolite asbestos
    • Fung H., Kow Y.W., Van Houten B., Mossman B.T. Patterns of 8-hydroxydeoxyguanosine formation in DNA and indications of oxidative stress in rat and human pleural mesothelial cells after exposure to crocidolite asbestos. Carcinogenesis 1997, 18(4):825-832.
    • (1997) Carcinogenesis , vol.18 , Issue.4 , pp. 825-832
    • Fung, H.1    Kow, Y.W.2    Van Houten, B.3    Mossman, B.T.4
  • 46
    • 12344332702 scopus 로고    scopus 로고
    • DNA damage in bronchial epithelial and mesothelial cells with and without associated crocidolite asbestos fibers
    • Nygren J., Suhonen S., Norppa H., Linnainmaa K. DNA damage in bronchial epithelial and mesothelial cells with and without associated crocidolite asbestos fibers. Environ. Mol. Mutagen. 2004, 44(5):477-482.
    • (2004) Environ. Mol. Mutagen. , vol.44 , Issue.5 , pp. 477-482
    • Nygren, J.1    Suhonen, S.2    Norppa, H.3    Linnainmaa, K.4
  • 47
    • 0037152630 scopus 로고    scopus 로고
    • The molecular epidemiology of asbestos and tobacco in lung cancer
    • Nelson H.H., Kelsey K.T. The molecular epidemiology of asbestos and tobacco in lung cancer. Oncogene 2002, 21(48):7284-7288.
    • (2002) Oncogene , vol.21 , Issue.48 , pp. 7284-7288
    • Nelson, H.H.1    Kelsey, K.T.2
  • 48
    • 33751504957 scopus 로고    scopus 로고
    • Upgrading the BCL-2 network
    • Galonek H.L., Hardwick J.M. Upgrading the BCL-2 network. Nat. Cell Biol. 2006, 8(12):1317-1319.
    • (2006) Nat. Cell Biol. , vol.8 , Issue.12 , pp. 1317-1319
    • Galonek, H.L.1    Hardwick, J.M.2
  • 51
    • 0032537024 scopus 로고    scopus 로고
    • Loss of protein kinase C function induces an apoptotic response
    • Whelan R.D., Parker P.J. Loss of protein kinase C function induces an apoptotic response. Oncogene 1998, 16(15):1939-1944.
    • (1998) Oncogene , vol.16 , Issue.15 , pp. 1939-1944
    • Whelan, R.D.1    Parker, P.J.2
  • 52
    • 0036087033 scopus 로고    scopus 로고
    • Increased localization and substrate activation of protein kinase C delta in lung epithelial cells following exposure to asbestos
    • Lounsbury K.M., Stern M., Taatjes D., Jaken S., Mossman B.T. Increased localization and substrate activation of protein kinase C delta in lung epithelial cells following exposure to asbestos. Am. J. Pathol. 2002, 160:1991-2000.
    • (2002) Am. J. Pathol. , vol.160 , pp. 1991-2000
    • Lounsbury, K.M.1    Stern, M.2    Taatjes, D.3    Jaken, S.4    Mossman, B.T.5
  • 54
    • 59649097080 scopus 로고    scopus 로고
    • A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos
    • Buder-Hoffmann S.A., Shukla A., Barrett T.F., MacPherson M.B., Lounsbury K.M., Mossman B.T. A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos. Am. J. Pathol. 2009, 174(2):449-459.
    • (2009) Am. J. Pathol. , vol.174 , Issue.2 , pp. 449-459
    • Buder-Hoffmann, S.A.1    Shukla, A.2    Barrett, T.F.3    MacPherson, M.B.4    Lounsbury, K.M.5    Mossman, B.T.6
  • 55
    • 42549144606 scopus 로고    scopus 로고
    • Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis
    • Rong Y., Distelhorst C.W. Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis. Annu. Rev. Physiol. 2008, 70:73-91.
    • (2008) Annu. Rev. Physiol. , vol.70 , pp. 73-91
    • Rong, Y.1    Distelhorst, C.W.2
  • 56
    • 54949135707 scopus 로고    scopus 로고
    • The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family
    • Heath-Engel H.M., Chang N.C., Shore G.C. The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family. Oncogene 2008, 27(50):6419-6433.
    • (2008) Oncogene , vol.27 , Issue.50 , pp. 6419-6433
    • Heath-Engel, H.M.1    Chang, N.C.2    Shore, G.C.3
  • 57
    • 57349100367 scopus 로고    scopus 로고
    • Mitofusin 2 tethers endoplasmic reticulum to mitochondria
    • de Brito O.M., Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 2008, 456(7222):605-610.
    • (2008) Nature , vol.456 , Issue.7222 , pp. 605-610
    • de Brito, O.M.1    Scorrano, L.2
  • 58
    • 76749165731 scopus 로고    scopus 로고
    • Sigma-1 receptors regulate Bcl-2 expression by ROS-dependent transcriptional regulation of NF-{kappa}B
    • Meunier J., Hayashi T. Sigma-1 receptors regulate Bcl-2 expression by ROS-dependent transcriptional regulation of NF-{kappa}B. J. Pharmacol. Exp. Ther. 2010, 332(2):388-397.
    • (2010) J. Pharmacol. Exp. Ther. , vol.332 , Issue.2 , pp. 388-397
    • Meunier, J.1    Hayashi, T.2
  • 61
    • 0034604033 scopus 로고    scopus 로고
    • Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2
    • Hacki J., Egger L., Monney L., Conus S., Rosse T., Fellay I., Borner C. Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2. Oncogene 2000, 19(19):2286-2295.
    • (2000) Oncogene , vol.19 , Issue.19 , pp. 2286-2295
    • Hacki, J.1    Egger, L.2    Monney, L.3    Conus, S.4    Rosse, T.5    Fellay, I.6    Borner, C.7
  • 62
  • 63
    • 67649547153 scopus 로고    scopus 로고
    • Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak
    • Klee M., Pallauf K., Alcala S., Fleischer A., Pimentel-Muinos F.X. Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak. EMBO J. 2009, 28(12):1757-1768.
    • (2009) EMBO J. , vol.28 , Issue.12 , pp. 1757-1768
    • Klee, M.1    Pallauf, K.2    Alcala, S.3    Fleischer, A.4    Pimentel-Muinos, F.X.5
  • 65
    • 85069279585 scopus 로고    scopus 로고
    • Asbestos induces an endoplasmic reticulum stress response in alveolar epithelial cells, Am. J. Resp. Crit. Care Med., in press (Abstract)
    • R. Beri, G. Liu, A. Mueller, H. Trejo, D. Kamp, Asbestos induces an endoplasmic reticulum stress response in alveolar epithelial cells, Am. J. Resp. Crit. Care Med., in press (Abstract).
    • Beri, R.1    Liu, G.2    Mueller, A.3    Trejo, H.4    Kamp, D.5
  • 66
    • 44049092395 scopus 로고    scopus 로고
    • The dark side of a tumor suppressor: anti-apoptotic p53
    • Janicke R.U., Sohn D., Schulze-Osthoff K. The dark side of a tumor suppressor: anti-apoptotic p53. Cell Death Differ. 2008, 15(6):959-976.
    • (2008) Cell Death Differ. , vol.15 , Issue.6 , pp. 959-976
    • Janicke, R.U.1    Sohn, D.2    Schulze-Osthoff, K.3
  • 67
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: the growing complexity of p53
    • Vousden K.H., Prives C. Blinded by the light: the growing complexity of p53. Cell 2009, 137(3):413-431.
    • (2009) Cell , vol.137 , Issue.3 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 68
    • 0034922777 scopus 로고    scopus 로고
    • Enhancement of fibrogenesis by the p53 tumor suppressor protein in asbestos-exposed rodents
    • Nelson A., Mendoza T., Hoyle G.W., Brody A.R., Fermin C., Morris G.F. Enhancement of fibrogenesis by the p53 tumor suppressor protein in asbestos-exposed rodents. Chest 2001, 120(1 Suppl):33S-34S.
    • (2001) Chest , vol.120 , Issue.SUPPL.1
    • Nelson, A.1    Mendoza, T.2    Hoyle, G.W.3    Brody, A.R.4    Fermin, C.5    Morris, G.F.6
  • 70
    • 1242272152 scopus 로고    scopus 로고
    • Effects of asbestos on initiation of DNA damage, induction of DNA-strand breaks, P53-expression and apoptosis in primary, SV40-transformed and malignant human mesothelial cells
    • Burmeister B., Schwerdtle T., Poser I., Hoffmann E., Hartwig A., Muller W.U., Rettenmeier A.W., Seemayer N.H., Dopp E. Effects of asbestos on initiation of DNA damage, induction of DNA-strand breaks, P53-expression and apoptosis in primary, SV40-transformed and malignant human mesothelial cells. Mutat. Res. 2004, 558(1-2):81-92.
    • (2004) Mutat. Res. , vol.558 , Issue.1-2 , pp. 81-92
    • Burmeister, B.1    Schwerdtle, T.2    Poser, I.3    Hoffmann, E.4    Hartwig, A.5    Muller, W.U.6    Rettenmeier, A.W.7    Seemayer, N.H.8    Dopp, E.9
  • 71
    • 13844314302 scopus 로고    scopus 로고
    • Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis
    • Plataki M., Koutsopoulos A.V., Darivianaki K., Delides G., Siafakas N.M., Bouros D. Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis. Chest 2005, 127(1):266-274.
    • (2005) Chest , vol.127 , Issue.1 , pp. 266-274
    • Plataki, M.1    Koutsopoulos, A.V.2    Darivianaki, K.3    Delides, G.4    Siafakas, N.M.5    Bouros, D.6
  • 72
    • 17344391681 scopus 로고    scopus 로고
    • P53, Cip1, and Gadd153 expression following treatment of A549 cells with natural and man-made vitreous fibers
    • Johnson N.F., Jaramillo R.J. p53, Cip1, and Gadd153 expression following treatment of A549 cells with natural and man-made vitreous fibers. Environ. Health Perspect. 1997, 105(Suppl. 5):1143-1145.
    • (1997) Environ. Health Perspect. , vol.105 , Issue.SUPPL. 5 , pp. 1143-1145
    • Johnson, N.F.1    Jaramillo, R.J.2
  • 74
    • 0038746801 scopus 로고    scopus 로고
    • Phosphorylation of p53 protein in A549 human pulmonary epithelial cells exposed to asbestos fibers
    • Matsuoka M., Igisu H., Morimoto Y. Phosphorylation of p53 protein in A549 human pulmonary epithelial cells exposed to asbestos fibers. Environ. Health Perspect. 2003, 111(4):509-512.
    • (2003) Environ. Health Perspect. , vol.111 , Issue.4 , pp. 509-512
    • Matsuoka, M.1    Igisu, H.2    Morimoto, Y.3
  • 75
    • 9944230966 scopus 로고    scopus 로고
    • Cell type-specific effects of asbestos on intracellular ROS levels, DNA oxidation and G1 cell cycle checkpoint
    • Kopnin P.B., Kravchenko I.V., Furalyov V.A., Pylev L.N., Kopnin B.P. Cell type-specific effects of asbestos on intracellular ROS levels, DNA oxidation and G1 cell cycle checkpoint. Oncogene 2004, 23(54):8834-8840.
    • (2004) Oncogene , vol.23 , Issue.54 , pp. 8834-8840
    • Kopnin, P.B.1    Kravchenko, I.V.2    Furalyov, V.A.3    Pylev, L.N.4    Kopnin, B.P.5
  • 78
    • 0033774464 scopus 로고    scopus 로고
    • Crocidolite induces cell transformation and p53 gene mutation in BALB/c-3T3 cells
    • Lin F., Liu Y., Keshava N., Li S. Crocidolite induces cell transformation and p53 gene mutation in BALB/c-3T3 cells. Teratog. Carcinog. Mutagen. 2000, 20(5):273-281.
    • (2000) Teratog. Carcinog. Mutagen. , vol.20 , Issue.5 , pp. 273-281
    • Lin, F.1    Liu, Y.2    Keshava, N.3    Li, S.4
  • 79
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995, 80(2):293-299.
    • (1995) Cell , vol.80 , Issue.2 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 81
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano K., Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 2001, 7(3):683-694.
    • (2001) Mol. Cell , vol.7 , Issue.3 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 83
    • 0034717014 scopus 로고    scopus 로고
    • Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
    • Marchenko N.D., Zaika A., Moll U.M. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J. Biol. Chem. 2000, 275(21):16202-16212.
    • (2000) J. Biol. Chem. , vol.275 , Issue.21 , pp. 16202-16212
    • Marchenko, N.D.1    Zaika, A.2    Moll, U.M.3
  • 84
    • 0242552555 scopus 로고    scopus 로고
    • Influence of induced reactive oxygen species in p53-mediated cell fate decisions
    • Macip S., Igarashi M., Berggren P., Yu J., Lee S.W., Aaronson S.A. Influence of induced reactive oxygen species in p53-mediated cell fate decisions. Mol. Cell Biol. 2003, 23(23):8576-8585.
    • (2003) Mol. Cell Biol. , vol.23 , Issue.23 , pp. 8576-8585
    • Macip, S.1    Igarashi, M.2    Berggren, P.3    Yu, J.4    Lee, S.W.5    Aaronson, S.A.6
  • 86
    • 51349127794 scopus 로고    scopus 로고
    • Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions
    • Hevel J.M., Olson-Buelow L.C., Ganesan B., Stevens J.R., Hardman J.P., Aust A.E. Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions. BMC Genomics 2008, 9:376.
    • (2008) BMC Genomics , vol.9 , pp. 376
    • Hevel, J.M.1    Olson-Buelow, L.C.2    Ganesan, B.3    Stevens, J.R.4    Hardman, J.P.5    Aust, A.E.6
  • 87
    • 13944257800 scopus 로고    scopus 로고
    • Transcription Apoptosis and p53: catch-22
    • Schuler M., Green D.R., Transcription apoptosis and p53: catch-22. Trends Genet. 2005, 21(3):182-187.
    • (2005) Trends Genet. , vol.21 , Issue.3 , pp. 182-187
    • Schuler, M.1    Green, D.R.2
  • 88
    • 3242690522 scopus 로고    scopus 로고
    • In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
    • Erster S., Mihara M., Kim R.H., Petrenko O., Moll U.M. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol. Cell Biol. 2004, 24(15):6728-6741.
    • (2004) Mol. Cell Biol. , vol.24 , Issue.15 , pp. 6728-6741
    • Erster, S.1    Mihara, M.2    Kim, R.H.3    Petrenko, O.4    Moll, U.M.5
  • 89
    • 16444382174 scopus 로고    scopus 로고
    • PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells
    • Liu Z., Lu H., Shi H., Du Y., Yu J., Gu S., Chen X., Liu K.J., Hu C.A. PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells. Cancer Res. 2005, 65(5):1647-1654.
    • (2005) Cancer Res. , vol.65 , Issue.5 , pp. 1647-1654
    • Liu, Z.1    Lu, H.2    Shi, H.3    Du, Y.4    Yu, J.5    Gu, S.6    Chen, X.7    Liu, K.J.8    Hu, C.A.9
  • 91
    • 4544381708 scopus 로고    scopus 로고
    • Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways
    • Yamaguchi H., Chen J., Bhalla K., Wang H.G. Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways. J. Biol. Chem. 2004, 279(38):39431-39437.
    • (2004) J. Biol. Chem. , vol.279 , Issue.38 , pp. 39431-39437
    • Yamaguchi, H.1    Chen, J.2    Bhalla, K.3    Wang, H.G.4
  • 92
    • 33846997899 scopus 로고    scopus 로고
    • Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa
    • Naik E., Michalak E.M., Villunger A., Adams J.M., Strasser A. Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. J. Cell Biol. 2007, 176(4):415-424.
    • (2007) J. Cell Biol. , vol.176 , Issue.4 , pp. 415-424
    • Naik, E.1    Michalak, E.M.2    Villunger, A.3    Adams, J.M.4    Strasser, A.5
  • 97
    • 67349150662 scopus 로고    scopus 로고
    • Repression of the BH3-only molecule PMAIP1/Noxa impairs glucocorticoid sensitivity of acute lymphoblastic leukemia cells
    • Ploner C., Rainer J., Lobenwein S., Geley S., Kofler R. Repression of the BH3-only molecule PMAIP1/Noxa impairs glucocorticoid sensitivity of acute lymphoblastic leukemia cells. Apoptosis 2009, 14(6):821-828.
    • (2009) Apoptosis , vol.14 , Issue.6 , pp. 821-828
    • Ploner, C.1    Rainer, J.2    Lobenwein, S.3    Geley, S.4    Kofler, R.5
  • 98
    • 0037029132 scopus 로고    scopus 로고
    • Mitochondrial DNA repair of oxidative damage in mammalian cells
    • Bohr V.A., Stevnsner T., de Souza-Pinto N.C. Mitochondrial DNA repair of oxidative damage in mammalian cells. Gene 2002, 286(1):127-134.
    • (2002) Gene , vol.286 , Issue.1 , pp. 127-134
    • Bohr, V.A.1    Stevnsner, T.2    de Souza-Pinto, N.C.3
  • 99
    • 30344432706 scopus 로고    scopus 로고
    • Role of mitochondrial DNA in toxic responses to oxidative stress
    • Van Houten B., Woshner V., Santos J.H. Role of mitochondrial DNA in toxic responses to oxidative stress. DNA Rep. (Amst.) 2006, 5(2):145-152.
    • (2006) DNA Rep. (Amst.) , vol.5 , Issue.2 , pp. 145-152
    • Van Houten, B.1    Woshner, V.2    Santos, J.H.3
  • 100
    • 7744246367 scopus 로고    scopus 로고
    • Life's smile, death's grin: vital functions of apoptosis-executing proteins
    • Garrido C., Kroemer G. Life's smile, death's grin: vital functions of apoptosis-executing proteins. Curr. Opin. Cell Biol. 2004, 16(6):639-646.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , Issue.6 , pp. 639-646
    • Garrido, C.1    Kroemer, G.2
  • 101
    • 3042739635 scopus 로고    scopus 로고
    • Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases
    • Russo M.T., De Luca G., Degan P., Parlanti E., Dogliotti E., Barnes D.E., Lindahl T., Yang H., Miller J.H., Bignami M. Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases. Cancer Res. 2004, 64(13):4411-4414.
    • (2004) Cancer Res. , vol.64 , Issue.13 , pp. 4411-4414
    • Russo, M.T.1    De Luca, G.2    Degan, P.3    Parlanti, E.4    Dogliotti, E.5    Barnes, D.E.6    Lindahl, T.7    Yang, H.8    Miller, J.H.9    Bignami, M.10
  • 102
    • 0027171266 scopus 로고
    • Oxidants, antioxidants, and the degenerative diseases of aging
    • Ames B.N., Shigenaga M.K., Hagen T.M. Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. U.S.A. 1993, 90(17):7915-7922.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , Issue.17 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 103
    • 0032508052 scopus 로고    scopus 로고
    • Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours
    • Chevillard S., Radicella J.P., Levalois C., Lebeau J., Poupon M.F., Oudard S., Dutrillaux B., Boiteux S. Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours. Oncogene 1998, 16(23):3083-3086.
    • (1998) Oncogene , vol.16 , Issue.23 , pp. 3083-3086
    • Chevillard, S.1    Radicella, J.P.2    Levalois, C.3    Lebeau, J.4    Poupon, M.F.5    Oudard, S.6    Dutrillaux, B.7    Boiteux, S.8
  • 104
    • 0030912695 scopus 로고    scopus 로고
    • Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue
    • Aburatani H., Hippo Y., Ishida T., Takashima R., Matsuba C., Kodama T., Takao M., Yasui A., Yamamoto K., Asano M. Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue. Cancer Res. 1997, 57(11):2151-2156.
    • (1997) Cancer Res. , vol.57 , Issue.11 , pp. 2151-2156
    • Aburatani, H.1    Hippo, Y.2    Ishida, T.3    Takashima, R.4    Matsuba, C.5    Kodama, T.6    Takao, M.7    Yasui, A.8    Yamamoto, K.9    Asano, M.10
  • 107
    • 33644661625 scopus 로고    scopus 로고
    • Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis
    • Rachek L.I., Grishko V.I., Ledoux S.P., Wilson G.L. Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis. Free Radic. Biol. Med. 2006, 40(5):754-762.
    • (2006) Free Radic. Biol. Med. , vol.40 , Issue.5 , pp. 754-762
    • Rachek, L.I.1    Grishko, V.I.2    Ledoux, S.P.3    Wilson, G.L.4
  • 109
    • 0028075773 scopus 로고
    • Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs
    • Gardner P.R., Nguyen D.D., White C.W. Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs. Proc. Natl. Acad. Sci. U.S.A. 1994, 91(25):12248-12252.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , Issue.25 , pp. 12248-12252
    • Gardner, P.R.1    Nguyen, D.D.2    White, C.W.3
  • 110
    • 0346365099 scopus 로고    scopus 로고
    • Redox-dependent modulation of aconitase activity in intact mitochondria
    • Bulteau A.L., Ikeda-Saito M., Szweda L.I. Redox-dependent modulation of aconitase activity in intact mitochondria. Biochemistry 2003, 42(50):14846-14855.
    • (2003) Biochemistry , vol.42 , Issue.50 , pp. 14846-14855
    • Bulteau, A.L.1    Ikeda-Saito, M.2    Szweda, L.I.3
  • 111
    • 13244277441 scopus 로고    scopus 로고
    • Aconitase couples metabolic regulation to mitochondrial DNA maintenance
    • Chen X.J., Wang X., Kaufman B.A., Butow R.A. Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 2005, 307(5710):714-717.
    • (2005) Science , vol.307 , Issue.5710 , pp. 714-717
    • Chen, X.J.1    Wang, X.2    Kaufman, B.A.3    Butow, R.A.4
  • 112
    • 3042763187 scopus 로고    scopus 로고
    • Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity
    • Bulteau A.L., O'Neill H.A., Kennedy M.C., Ikeda-Saito M., Isaya G., Szweda L.I. Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity. Science 2004, 305(5681):242-245.
    • (2004) Science , vol.305 , Issue.5681 , pp. 242-245
    • Bulteau, A.L.1    O'Neill, H.A.2    Kennedy, M.C.3    Ikeda-Saito, M.4    Isaya, G.5    Szweda, L.I.6
  • 113
    • 35948982963 scopus 로고    scopus 로고
    • Human 8-oxoguanine DNA glycosylase suppresses the oxidative stress induced apoptosis through a p53-mediated signaling pathway in human fibroblasts
    • Youn C.K., Song P.I., Kim M.H., Kim J.S., Hyun J.W., Choi S.J., Yoon S.P., Chung M.H., Chang I.Y., You H.J. Human 8-oxoguanine DNA glycosylase suppresses the oxidative stress induced apoptosis through a p53-mediated signaling pathway in human fibroblasts. Mol. Cancer Res. 2007, 5(10):1083-1098.
    • (2007) Mol. Cancer Res. , vol.5 , Issue.10 , pp. 1083-1098
    • Youn, C.K.1    Song, P.I.2    Kim, M.H.3    Kim, J.S.4    Hyun, J.W.5    Choi, S.J.6    Yoon, S.P.7    Chung, M.H.8    Chang, I.Y.9    You, H.J.10
  • 114
    • 37349058929 scopus 로고    scopus 로고
    • Increased ROS generation in subsets of OGG1 knockout fibroblast cells
    • Bacsi A., Chodaczek G., Hazra T.K., Konkel D., Boldogh I. Increased ROS generation in subsets of OGG1 knockout fibroblast cells. Mech. Ageing Dev. 2007, 128(11-12):637-649.
    • (2007) Mech. Ageing Dev. , vol.128 , Issue.11-12 , pp. 637-649
    • Bacsi, A.1    Chodaczek, G.2    Hazra, T.K.3    Konkel, D.4    Boldogh, I.5
  • 115
    • 41949100227 scopus 로고    scopus 로고
    • Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation
    • Xie Y., Yang H., Miller J.H., Shih D.M., Hicks G.G., Xie J., Shiu R.P. Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation. Carcinogenesis 2008, 29(4):722-728.
    • (2008) Carcinogenesis , vol.29 , Issue.4 , pp. 722-728
    • Xie, Y.1    Yang, H.2    Miller, J.H.3    Shih, D.M.4    Hicks, G.G.5    Xie, J.6    Shiu, R.P.7
  • 116
    • 0036713692 scopus 로고    scopus 로고
    • Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
    • Bota D.A., Davies K.J. Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. Nat. Cell Biol. 2002, 4(9):674-680.
    • (2002) Nat. Cell Biol. , vol.4 , Issue.9 , pp. 674-680
    • Bota, D.A.1    Davies, K.J.2
  • 117
    • 0037021453 scopus 로고    scopus 로고
    • Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress
    • Bota D.A., Van Remmen H., Davies K.J. Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress. FEBS Lett. 2002, 532(1-2):103-106.
    • (2002) FEBS Lett. , vol.532 , Issue.1-2 , pp. 103-106
    • Bota, D.A.1    Van Remmen, H.2    Davies, K.J.3
  • 118
    • 0023679752 scopus 로고
    • Mitochondria contain a proteolytic system which can recognize and degrade oxidatively-denatured proteins
    • Marcillat O., Zhang Y., Lin S.W., Davies K.J. Mitochondria contain a proteolytic system which can recognize and degrade oxidatively-denatured proteins. Biochem. J. 1988, 254(3):677-683.
    • (1988) Biochem. J. , vol.254 , Issue.3 , pp. 677-683
    • Marcillat, O.1    Zhang, Y.2    Lin, S.W.3    Davies, K.J.4
  • 119
    • 0021951263 scopus 로고
    • Endogenous free radical generation may influence proteolysis in mitochondria
    • Dean R.T., Pollak J.K. Endogenous free radical generation may influence proteolysis in mitochondria. Biochem. Biophys. Res. Commun. 1985, 126(3):1082-1089.
    • (1985) Biochem. Biophys. Res. Commun. , vol.126 , Issue.3 , pp. 1082-1089
    • Dean, R.T.1    Pollak, J.K.2
  • 120
    • 33750742792 scopus 로고    scopus 로고
    • Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress
    • Chatterjee A., Mambo E., Zhang Y., Deweese T., Sidransky D. Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress. BMC Cancer 2006, 6:235.
    • (2006) BMC Cancer , vol.6 , pp. 235
    • Chatterjee, A.1    Mambo, E.2    Zhang, Y.3    Deweese, T.4    Sidransky, D.5
  • 122
    • 0034708226 scopus 로고    scopus 로고
    • Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
    • Bruner S.D., Norman D.P., Verdine G.L. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature 2000, 403(6772):859-866.
    • (2000) Nature , vol.403 , Issue.6772 , pp. 859-866
    • Bruner, S.D.1    Norman, D.P.2    Verdine, G.L.3
  • 123
    • 9244239263 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial DNA repair: implications for NRTIs induced DNA damage
    • Hashiguchi K., Bohr V.A., de Souza-Pinto N.C. Oxidative stress and mitochondrial DNA repair: implications for NRTIs induced DNA damage. Mitochondrion 2004, 4(2-3):215-222.
    • (2004) Mitochondrion , vol.4 , Issue.2-3 , pp. 215-222
    • Hashiguchi, K.1    Bohr, V.A.2    de Souza-Pinto, N.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.