Human 8-oxoguanine DNA glycosylase suppresses the oxidative stress-induced apoptosis through a p53-mediated signaling pathway in human fibroblasts

Molecular Cancer Research

Volumn 5, Issue 10, 2007, Pages 1083-1098

  Youn, Cha Kyung ^a   Song, Peter I ^a,b   Kim, Mi Hwa ^a   Jin, Sook Kim ^c   Hyun, Jin Won ^d   Choi, Sang Joon ^a   Sang, Pil Yoon ^e   Myung, Hee Chung ^f   Chang, In Youb ^a   Ho, Jin You ^a  

^a Chosun University   (South Korea)

^b UNIVERSITY OF COLORADO   (United States)

^c Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^d Jeju National University School of Medicine   (South Korea)

^e Seonam University   (South Korea)

^f Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; CASPASE 3; CASPASE 7; DNA GLYCOSYLTRANSFERASE; HUMAN 8 OXOGUANINE DNA GLYCOSYLASE; HYDROGEN PEROXIDE; PROTEIN NOXA; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CHROMOSOME; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; FIBROBLAST; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; INHIBITION KINETICS; LUNG CARCINOMA; NULL CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; WILD TYPE;

APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CELL SURVIVAL; DNA DAMAGE; DNA GLYCOSYLASES; FIBROBLASTS; HUMANS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 35948982963     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-06-0432     Document Type: Article

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