Aconitase couples metabolic regulation to mitochondrial DNA maintenance

Science

Volumn 307, Issue 5710, 2005, Pages 714-717

  Xin, Jie Chen ^a   Wang, Xiaowen ^a   Kaufman, Brett A ^a,b   Butow, Ronald A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELLS; DNA; METABOLISM; RESPIRATORY MECHANICS; YEAST;

ACONITASE; METABOLIC SIGNALS; MITOCHONDRIAL DNA (MTDNA); SIGNALING PATHWAYS;

ENZYMES;

ACONITATE HYDRATASE; HIGH MOBILITY GROUP PROTEIN; MITOCHONDRIAL DNA;

MITOCHONDRIAL DNA;

ARTICLE; CATALYSIS; CELL AGING; CITRIC ACID CYCLE; DNA DETERMINATION; DNA PACKAGING; DNA PROTEIN COMPLEX; ENZYME ACTIVATION; ENZYME REGULATION; GENE EXPRESSION; METABOLIC REGULATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; YEAST;

ALLELES; AMINO ACID SUBSTITUTION; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CCAAT-BINDING FACTOR; DNA, FUNGAL; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GLUCOSE; IRON REGULATORY PROTEIN 1; MUTATION; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SPORES, FUNGAL; TRANSCRIPTION FACTORS; TRANSFORMATION, GENETIC;

EID: 13244277441     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1106391     Document Type: Article

References (30)

1. B. A. Kaufman et al., Proc. Natl. Acad. Sci. U.S.A. 97, 7772 (2000).
2. S. Meeusen et al., J. Cell Biol. 145, 291 (1999).
3. I. Miyakawa, N. Sando, K. Kawano, S. Nakamura, T. Kuroiwa, J. Cell Sci. 88, 431 (1987).
4. N. Garrido et al., Mol. Biol. Cell 14, 1583 (2003).
5. D. F. Bogenhagen, Y. Wang, E. L. Shen, R. Kobayashi, Mol. Cell. Proteomics 2, 1205 (2003).
6. J. F. Diffley, B. Stillman, Proc. Natl. Acad. Sci. U.S.A. 88, 7864 (1991).
7. N. O. Larsson et al., Nature Genet. 18, 231 (1998).
8. B. A. Kaufman, J. E. Kolesar, P. S. Perlman, R. A. Butow, J. Cell Biol. 163, 457 (2003).
9. H. Sato, A. Tachifuji, M. Tamura, I. Miyakawa, Protoplasma 219, 51 (2002).
10. J. L. DeRisi, V. R. Iyer, P. O. Brown, Science 278, 680 (1997).
11. M. T. McCammon, C. B. Epstein, B. Przybyla-Zawislak, L McAlister-Henn, R. A. Butow, Mol. Biol. Cell 14, 958 (2003).
12. Z. Liu, R. A. Butow, Mol. Cell. Biol. 19, 6720 (1999).
13. R. A. Butow, N. O. Avadhani, Mol. Cell 14, 1 (2004).
14. Y. K. Jia, A. M. Becam, C. J. Herbert, Mol. Microbiol. 24, 53 (1997).
15. C. B. Epstein et al., Mol. Biol. Cell 12, 297 (2001).
16. A. H. Robbins, C. D. Stout, Proc. Natl. Acad. Sci. U.S.A. 86, 3639 (1989).
17. H. Lauble, M. C. Kennedy, H. Beinert, C. D. Stout, J. Mol. Biol. 237, 437 (1994).
18. H. Hirling, B. R. Henderson, L. C. Kuhn, EMBO J. 13, 453 (1994).
19. T. L. Megraw, C. B. Chae, J. Biol. Chem. 268, 12758 (1993).
20. J. Blom, M. J. De Mattos, L A. Grivell, Appl. Environ. Microbiol. 66, 1970 (2000).
21. I. Dilova, C.-Y. Chen, T. Powers, Curr. Biol. 12, 389 (2002).
22. T. Sekito, Z. Liu, J. Thornton, R. A. Butow, Mol. Biol. Cell 13, 795 (2002).
23. J. J. Tate, K. H. Cox, R. Rai, T. G. Cooper, J. Biol. Chem. 277, 20477 (2002).
24. J.-J. Lawrence, M. Daune, Biochemistry 15, 3301 (1976).
25. M. C. Kennedy, L. Mende-Mueller, G. A. Blondin, H. Beinert, Proc. Natl. Acad. Sci. U.S.A. 89, 11730 (1992).
26. R. D. Klausner, T. A. Rouault, Mol. Biol. Cell 4, 1 (1993).
27. M. D. Williams et al., J. Biol. Chem. 273, 28510 (1998).
28. L. J. Yan, R. L. Levine, R. S. Sohal, Proc. Natl. Acad. Sci. U.S.A. 94, 11168 (1997).
29. J. L. Bradley et al., Hum. Mol. Genet. 9, 275 (2000).
30. We thank R. Lill for the generous gift of antibody to aconitase. Supported by NIH grant nos. GM33510 and GM22525 and by Welch Foundation grant no. I-0642.