Targeting and processing of site-specific DNA interstrand crosslinks

Environmental and Molecular Mutagenesis

Volumn 51, Issue 6, 2010, Pages 527-539

  Vasquez, Karen M ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

DNA interstrand crosslink; DNA repair; Psoralen; Triplex

Indexed keywords

CARBOPLATIN; CHECKPOINT KINASE 2; CISPLATIN; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FANCONI ANEMIA PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; MISMATCH REPAIR PROTEIN PMS2; NUCLEIC ACID BINDING PROTEIN; PROTEIN MLH1; PROTEIN MSH2; PSORALEN; REPLICATION FACTOR A; TIOGUANINE; TRANSCRIPTION FACTOR IIH; XERODERMA PIGMENTOSUM GROUP A PROTEIN; XERODERMA PIGMENTOSUM GROUP C PROTEIN; XERODERMA PIGMENTOSUM GROUP D PROTEIN; CROSS LINKING REAGENT;

DNA CROSS LINKING; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; GENE TARGETING; HOMOLOGOUS RECOMBINATION; HUMAN; MAMMAL; MISMATCH REPAIR; NONHUMAN; PROTEIN BINDING; PUVA; REVIEW; ULTRAVIOLET A RADIATION; ANIMAL; BIOLOGICAL MODEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; GENETIC RECOMBINATION;

MAMMALIA; MUS;

ANIMALS; CROSS-LINKING REAGENTS; DNA MISMATCH REPAIR; DNA REPAIR; DRUG DELIVERY SYSTEMS; HUMANS; MODELS, BIOLOGICAL; RECOMBINATION, GENETIC;

EID: 77955855049     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20557     Document Type: Review

References (154)

1. Aboussekhra A, Biggerstaff M, Shivji MK, Vilpo JA, Moncollin V, Podust VN, Protic M, Hubscher U, Egly JM, Wood RD. 1995. Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell 80:859-868.
2. Adamson AW, Beardsley DI, Kim WJ, Gao Y, Baskaran R, Brown KD. 2005. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2. Mol Biol Cell 16:1513-1526.
3. Aebi S, Fink D, Gordon R, Kim HK, Zheng H, Fink JL, Howell SB. 1997. Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells. Clin Cancer Res 3:1763-1767.
4. Akkari YM, Bateman RL, Reifsteck CA, Olson SB, Grompe M. 2000. DNA replication is required To elicit cellular responses to psoralen-induced DNA interstrand cross-links. Mol Cell Biol 20:8283-8289.
5. Aquilina G, Crescenzi M, Bignami M. 1999. Mismatch repair, G(2)/M cell cycle arrest and lethality after DNA damage. Carcinogenesis 20:2317-2326.
6. Araki M, Masutani C, Maekawa T, Watanabe Y, Yamada A, Kusumoto R, Sakai D, Sugasawa K, Ohkuma Y, Hanaoka F. 2000. Reconstitution of damage DNA excision reaction from SV40 minichromosomes with purified nucleotide excision repair proteins. Mutat Res 459:147-160.
7. Averbeck D. 1985. Relationship between lesions photoinduced by mono- and bi-functional furocoumarins in DNA, genotoxic effects in diploid yeast. Mutat Res 151:217-233.
8. Averbeck D, Averbeck S, Cundari E. 1987. Mutagenic and recombinogenic action of DNA monoadducts photoinduced by the bifunctional furocoumarin 8-methoxypsoralen in yeast (Saccharomyces cerevisiae). Photochem Photobiol 45:371-379.
9. Barre F-X, Asseline U, Harel-Bellan A. 1999a. Assymetric recognition of psoralen interstrand crosslinks by the nucleotide excision repair and the error-prone pathways. J Mol Biol 286:1379-1387.
10. Barre FX, Ait-Si-Ali S, Giovannangeli C, Luis R, Robin P, Pritchard LL, Helene C, Harel-Bellan A. 2000. Unambiguous demonstration of triple-helix-directed gene modification. Proc Natl Acad Sci USA 97:3084-3088.
11. Barre FX, Giovannangeli C, Helene C, Harel-Bellan A. 1999b. Covalent crosslinks introduced via a triple helix-forming oligonucleotide coupled to psoralen are inefficiently repaired. Nucleic Acids Res 27:743-749.
12. Beal PA, Dervan PB. 1991. Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation. Science 251:1360-1363.
13. Bergstralh DT, Sekelsky J. 2008. Interstrand crosslink repair: Can XPF-ERCC1 be let off the hook? Trends Genet 24:70-76.
14. Berti PJ, McCann JA. 2006. Toward a detailed understanding of base excision repair enzymes: Transition state and mechanistic analyses of N-glycoside hydrolysis and N-glycoside transfer. Chem Rev 106:506-555.
15. Bertrand P, Tishkoff DX, Filosi N, Dasgupta R, Kolodner RD. 1998. Physical interaction between components of DNA mismatch repair and nucleotide excision repair. Proc Natl Acad Sci USA 95:14278-14283.
16. Boulikas T, Vougiouka M. 2003. Cisplatin and platinum drugs at the molecular level (Review). Oncol Rep 10:1663-1682.
17. Brenneman M, Gimble FS, Wilson JH. 1996. Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases. Proc Natl Acad Sci USA 93:3608-3612.
18. Brown KD, Rathi A, Kamath R, Beardsley DI, Zhan Q, Mannino JL, Baskaran R. 2003. The mismatch repair system is required for Sphase checkpoint activation. Nat Genet 33:80-84.
19. Busch DB, van Vuuren H, de Wit J, Collins A, Zdzienicka MZ, Mitchell DL, Brookman KW, Stefanini M, Riboni R, Thompson LH, Albert RB, van Gool AJ, Hoeijmakers J. 1997. Phenotypic heterogeneity in nucleotide excision repair mutants of rodent complementation groups 1 and 4. Mutat Res 383:91-106.
20. Calmann MA, Marinus MG. 2004. MutS inhibits RecA-mediated strand exchange with platinated DNA substrates. Proc Natl Acad Sci USA 101:14174-14179.
21. Cejka P, Stojic L, Mojas N, Russell AM, Heinimann K, Cannavo E, di Pietro M, Marra G, Jiricny J. 2003. Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1. EMBO J 22:2245-2254.
22. Chan PP, Lin M, Faruqi AF, Powell J, Seidman MM, Glazer PM. 1999. Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide. J Biol Chem 274:11541-11548.
23. Cheng S, Sancar A, Hearst JE. 1991. RecA-dependent incision of psoralen- crosslinked DNA by (A)BC excinuclease. Nucleic Acids Res 19:657-663.
24. Chin JY, Glazer PM. 2009. Repair of DNA lesions associated with triplex-forming oligonucleotides. Mol Carcinog 48:389-399.
25. Choulika A, Perrin A, Dujon B, Nicolas JF. 1995. Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Mol Cell Biol 15:1968-1973.
26. Christensen LA, Conti CJ, Fischer SM, Vasquez KM. 2004. Mutation frequencies in murine keratinocytes as a function of carcinogenic status. Mol Carcinog 40:122-133.
27. Christensen LA, Wang H, Van Houten B, Vasquez KM. 2008. Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease. Nucleic Acids Res 36:7136-7145.
28. Cimino GD, Gamper HB, Isaacs ST, Hearst JE. 1985. Psoralens as photoactive probes of nucleic acid structure and function: Organic chemistry, photochemistry, and biochemistry. Annu Rev Biochem 54:1154-1193.
29. Cole RS. 1973a. Repair of DNA containing interstrand crosslinks in Escherichia coli: Sequential excision and recombination. Proc Natl Acad Sci USA 70:1064-1068.
30. Cole RS. 1973b. Repair of interstrand cross-links in DNA induced by psoralen plus light. Yale J Biol Med 46:492
31. Cooney M, Czernuszewicz G, Postel EH, Flint SJ, Hogan ME. 1988. Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro. Science 241:456-459.
32. Damia G, Guidi G, D'Incalci M. 1998. Expression of genes involved in nucleotide excision repair and sensitivity to cisplatin and melphalan in human cancer cell lines. Eur J Cancer 34:1783-1788.
33. Dardalhon M, Averbeck D. 1995. Pulsed-field gel electrophoresis analysis of the repair of psoralen plus UVA induced DNA photoadducts in Saccharomyces cerevisiae. Mutat Res 336:49-60.
34. Datta HJ, Chan PP, Vasquez KM, Gupta RC, Glazer PM. 2001. Triplex-induced recombination in human cell-free extracts. Dependence on XPA, HsRad51. J Biol Chem 276:18018-18023.
35. Davies AA, Friedberg EC, Tomkinson AE, Wood RD, West SC. 1995. Role of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination. J Biol Chem 270:24638-24641.
36. de Boer J, Hoeijmakers JH. 2000. Nucleotide excision repair and human syndromes. Carcinogenesis 21:453-460.
37. De Silva IU, McHugh PJ, Clingen PH, Hartley JA. 2000. Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol Cell Biol 20:7980-7990.
38. Degols G, Clarenc JP, Lebleu B, Leonetti JP. 1994. Reversible inhibition of gene expression by a psoralen functionalized triple helix forming oligonucleotide in intact cells. J Biol Chem 269:16933-16937.
39. Delacote F, Lopez BS. 2008. Importance of the cell cycle phase for the choice of the appropriate DSB repair pathway, for genome stability maintenance: The trans-S double-strand break repair model. Cell Cycle 7:33-38.
40. Dronkert ML, Kanaar R. 2001. Repair of DNA interstrand cross-links. Mutat Res 486:217-247.
41. Duca M, Vekhoff P, Oussedik K, Halby L, Arimondo PB. 2008. The triple helix: 50 years later, the outcome. Nucleic Acids Res 36:5123-5138.
42. Duckett DR, Drummond JT, Murchie AI, Reardon JT, Sancar A, Lilley DM, Modrich P. 1996. Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct. Proc Natl Acad Sci USA 93:6443-6447.
43. Fabisiewicz A, Worth L Jr. 2001. Escherichia coli MutS,L modulate RuvAB-dependent branch migration between diverged DNA. J Biol Chem 276:9413-9420.
44. Faruqi AF, Datta HJ, Carroll D, Seidman MM, Glazer PM. 2000. Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway. Mol Cell Biol 20:990-1000.
45. Faruqi AF, Egholm M, Glazer PM. 1998. Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells. Proc Natl Acad Sci USA 95:1398-1403.
46. Faruqi AF, Seidman MM, Segal DJ, Carroll D, Glazer PM. 1996. Recombination induced by triple helix-targeted DNA damage in mammalian cells. Mol Cell Biol 16:6820-6828.
47. Fedier A, Fink D. 2004. Mutations in DNA mismatch repair genes: Implications for DNA damage signaling and drug sensitivity (review). Int J Oncol 24:1039-1047.
48. Ferguson DO, Holloman WK. 1996. Recombinational repair of gaps in DNA is asymmetric in Ustilago maydis and can be explained by a migrating D-loop model. Proc Natl Acad Sci USA 93:5419-5424.
49. Fink D, Nebel S, Aebi S, Zheng H, Cenni B, Nehme A, Christen RD, Howell SB. 1996. The role of DNA mismatch repair in platinum drug resistance. Cancer Res 56:4881-4886. (Pubitemid 26374423)
50. Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R. 1993. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75:1027-1038. Erratum in Cell 1994; 77:167.
51. Fishman-Lobell J, Haber JE. 1992. Removal of nonhomologous DNA ends in double-strand break recombination: The role of the yeast ultraviolet repair gene RAD1. Science 258:480-484.
52. Gillet LC, Scharer OD. 2006. Molecular mechanisms of mammalian global genome nucleotide excision repair. Chem Rev 106:253-276.
53. Godwin AR, Bollag RJ, Christie DM, Liskay RM. 1994. Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells. Proc Natl Acad Sci USA 91:12554-12558.
54. Greenberg RB, Alberti M, Hearst JE, Chua MA, Saffran WA. 2001. Recombinational and mutagenic repair of psoralen interstrand cross-links in Saccharomyces cerevisiae. J Biol Chem 276:31551-31560.
55. Grompe M, D'Andrea A. 2001. Fanconi anemia and DNA repair. Hum Mol Genet 10:2253-2259.
56. Guzder SN, Habraken Y, Sung P, Prakash L, Prakash S. 1996. RAD26, the yeast homolog of human Cockayne's syndrome group B gene, encodes a DNA-dependent ATPase. J Biol Chem 271:18314-18317.
57. Hawn MT, Umar A, Carethers JM, Marra G, Kunkel TA, Boland CR, Koi M. 1995. Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint. Cancer Res 55:3721-3725.
58. He Z, Ingles CJ. 1997. Isolation of human complexes proficient in nucleotide excision repair. Nucleic Acids Res 25:1136-1141.
59. Hearst JE, Isaacs ST, Kanne D, Rapoport H, Straub K. 1984. The reaction of the psoralens with deoxyribonucleic acid. Q Rev Biophys 17:1-44.
60. Hickman MJ, Samson LD. 1999. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc Natl Acad Sci USA 96:10764-10769.
61. Hoy CA, Thompson LH, Mooney CL, Salazar EP. 1985. Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents. Cancer Res 45:1737-1743.
62. Ishino Y, Nishino T, Morikawa K. 2006. Mechanisms of maintaining genetic stability by homologous recombination. Chem Rev 106:324-339.
63. Iyer RR, Pluciennik A, Burdett V, Modrich PL. 2006. DNA mismatch repair: Functions and mechanisms. Chem Rev 106:302-323.
64. Jachymczyk WJ, von Borstel RC, Mowat MR, Hastings PJ. 1981. Repair of interstrand cross-links in DNA of Saccharomyces cerevisiae requires two systems for DNA repair: The RAD3 system and the RAD51 system. Mol Gen Genet 182:196-205.
65. Jain A, Wang G, Vasquez KM. 2008. DNA triple helices: Biological consequences and therapeutic potential. Biochimie 90:1117-1130.
66. Joerges C, Kuntze I, Herzinger T. 2003. Induction of a caffeine-sensitive S-phase cell cycle checkpoint by psoralen plus ultraviolet A radiation. Oncogene 22:6119-6128.
67. Kleijer WJ, Laugel V, Berneburg M, Nardo T, Fawcett H, Gratchev A, Jaspers NG, Sarasin A, Stefanini M, Lehmann AR. 2008. Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. DNA Repair (Amst) 7:744-750.
68. Kraemer KH, Patronas NJ, Schiffmann R, Brooks BP, Tamura D, DiGiovanna JJ. 2007. Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: A complex genotype-phenotype relationship. Neuroscience 145:1388-1396.
69. Kuraoka I, Kobertz WR, Ariza RR, Biggerstaff M, Essigmann JM, Wood RD. 2000. Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease. J Biol Chem 275:26632-26636.
70. Lan L, Hayashi T, Rabeya RM, Nakajima S, Kanno S, Takao M, Matsunaga T, Yoshino M, Ichikawa M, Riele H, et al. 2004. Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells. DNA Repair (Amst) 3:135-143.
71. Lange SS, Mitchell DL, Vasquez KM. 2008. High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage. Proc Natl Acad Sci USA 105:10320-10325.
72. Lange SS, Reddy MC, Vasquez KM. 2009. Human HMGB1 directly facilitates interactions between nucleotide excision repair proteins on triplex-directed psoralen interstrand crosslinks. DNA Repair (Amst) 8:865-872.
73. Lange SS, Vasquez KM. 2009. HMGB1: The jack-of-all-trades protein is a master DNA repair mechanic. Mol Carcinog 48:571-580.
74. Lawley PD, Phillips DH. 1996. DNA adducts from chemotherapeutic agents. Mutat Res 355:13-40.
75. Lehmann AR. 2003. DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. Biochimie 85:1101-1111.
76. Leibeling D, Laspe P, Emmert S. 2006. Nucleotide excision repair and cancer. J Mol Histol 37:225-238.
77. Li GM, Wang H, Romano LJ. 1996. Human MutSalpha specifically binds to DNA containing aminofluorene and acetylaminofluorene adducts. J Biol Chem 271:24084-24088.
78. Liu Y, Nairn RS, Vasquez KM. 2008. Processing of triplex-directed psoralen DNA interstrand crosslinks by recombination mechanisms. Nucleic Acids Res 36:4680-4688.
79. Liu Y, Nairn RS, Vasquez KM. 2009. Targeted gene conversion induced by triplex-directed psoralen interstrand crosslinks in mammalian cells. Nucleic Acids Res 37:6378-6388.
80. Luo Z, Macris MA, Faruqi AF, Glazer PM. 2000. High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells. Proc Natl Acad Sci USA 97:9003-9008.
81. Magana-Schwencke N, Henriques JA, Chanet R, Moustacchi E. 1982. The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: Comparison of wild-type and repair-deficient strains. Proc Natl Acad Sci USA 79:1722-1726.
82. Majumdar A, Khorlin A, Dyatkina N, Lin FL, Powell J, Liu J, Fei Z, Khripine Y, Watanabe KA, George J, et al. 1998. Targeted gene knockout mediated by triple helix forming oligonucleotides. Nat Genet 20:212-214.
83. Majumdar A, Puri N, Cuenoud B, Natt F, Martin P, Khorlin A, Dyatkina N, George AJ, Miller PS, Seidman MM. 2003. Cell cycle modulation of gene targeting by a triple helix-forming oligonucleotide. J Biol Chem 278:11072-11077.
84. Malkova A, Ivanov EL, Haber JE. 1996. Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication. Proc Natl Acad Sci USA 93:7131-7136.
85. McHugh PJ, Gill RD, Waters R, Hartley JA. 1999. Excision repair of nitrogen mustard-DNA adducts in Saccharomyces cerevisiae. Nucleic Acids Res 27:3259-3266.
86. McHugh PJ, Sarkar S. 2006. DNA interstrand cross-link repair in the cell cycle: A critical role for polymerase zeta in G1 phase. Cell Cycle 5:1044-1047.
87. McHugh PJ, Spanswick VJ, Hartley JA. 2001. Repair of DNA interstrand crosslinks: Molecular mechanisms and clinical relevance. Lancet Oncol 2:483-490.
88. Mello JA, Acharya S, Fishel R, Essigmann JM. 1996. The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin. Chem Biol 3:579-589.
89. Mishina Y, Duguid EM, He C. 2006. Direct reversal of DNA alkylation damage. Chem Rev 106:215-232.
90. Momtaz K, Fitzpatrick TB. 1998. The benefits and risks of long-term PUVA photochemotherapy. Dermatol Clin 16:227-234.
91. Mu D, Park CH, Matsunaga T, Hsu DS, Reardon JT, Sancar A. 1995. Reconstitution of human DNA repair excision nuclease in a highly defined system. J Biol Chem 270:2415-2418.
92. Musajo L, Rodighiero G, Dall'Acqua F. 1965. Evidences of a photoreaction of the photosensitizing furocoumarins with DNA, with pyrimidien nucleosides and nucleotides. Experimentia 21:24-26.
93. Mustra DJ, Warren AJ, Wilcox DE, Hamilton JW. 2007. Preferential binding of human XPA to the mitomycin C-DNA interstrand crosslink and modulation by arsenic and cadmium. Chem Biol Interact 168:159-168.
94. Nakanishi K, Yang YG, Pierce AJ, Taniguchi T, Digweed M, D'Andrea AD, Wang ZQ, Jasin M. 2005. Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci USA 102:1110-11115.
95. Nassif N, Penney J, Pal S, Engels WR, Gloor GB. 1994. Efficient copying of nonhomologous sequences from ectopic sites via P-element- induced gap repair. Mol Cell Biol 14:1613-1625.
96. Niedernhofer LJ, Essers J, Weeda G, Beverloo B, de Wit J, Muijtjens M, Odijk H, Hoeijmakers JH, Kanaar R. 2001. The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells. EMBO J 20:6540-6549.
97. Niedzwiedz W, Mosedale G, Johnson M, Ong CY, Pace P, Patel KJ. 2004. The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair. Mol Cell 15:607-620.
98. Noll DM, Mason TM, Miller PS. 2006. Formation and repair of interstrand cross-links in DNA. Chem Rev 106:277-301.
99. Oh DH, Hanawalt PC. 1999. Triple helix-forming oligonucleotides target psoralen adducts to specific chromosomal sequences in human cells. Nucleic Acids Res 27:4734-4742.
100. Oh DH, King BA, Boxer SG, Hanawalt PC. 2001. Spatially localized generation of nucleotide sequence-specific DNA damage. Proc Natl Acad Sci USA 98:11271-11276.
101. Papadopoulo D, Averbeck D, Moustacchi E. 1987. The fate of 8-methoxypsoralen- photoinduced DNA interstrand crosslinks in Fanconi's anemia cells of defined genetic complementation groups. Mutat Res 184:271-280.
102. Paques F, Haber JE. 1999. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 63:349-404.
103. Pavlovic-Calic N, Muminhodzic K, Zildzic M, Smajic M, Gegic A, Alibegovic E, Salkic N, Jovanovic P, Basic M, Iljazovic S. 2007. Genetics, clinical manifestations and management of FAP, HNPCC. Med Arh 61:256-259.
104. Peng M, Litman R, Xie J, Sharma S, Brosh RM Jr, Cantor SB. 2007. The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells. Embo J 26:3238-3249.
105. Perkins BD, Wensel TG, Vasquez KM, Wilson JH. 1999. Psoralen photo-cross- linking by triplex-forming oligonucleotides at multiple sites in the human rhodopsin gene. Biochemistry 38:12850-12859.
106. Pichierri P, Rosselli F. 2004. The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways. EMBO J 23:1178-1187.
107. Poll EH, Arwert F, Kortbeek HT, Eriksson AW. 1984. Fanconi anaemia cells are not uniformly deficient in unhooking of DNA interstrand crosslinks, induced by mitomycin C or 8-methoxypsoralen plus UVA. Hum Genet 68:228-234.
108. Rayssiguier C, Thaler DS, Radman M. 1989. The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature 342:396-401.
109. Reddy MC, Christensen J, Vasquez KM. 2005. Interplay between human high mobility group protein 1 and replication protein A on psoralen- cross-linked DNA. Biochemistry 44:4188-4195.
110. Reddy MC, Vasquez KM. 2005. Repair of genome destabilizing lesions. Radiat Res 164:345-356.
111. Richards S, Liu ST, Majumdar A, Liu JL, Nairn RS, Bernier M, Maher V, Seidman MM. 2005. Triplex targeted genomic crosslinks enter separable deletion and base substitution pathways. Nucleic Acids Res 33:5382-5393.
112. Rogers FA, Vasquez KM, Egholm M, Glazer PM. 2002. Site-directed recombination via bifunctional PNA-DNA conjugates. Proc Natl Acad Sci USA 99:16695-16700.
113. Rouet P, Smih F, Jasin M. 1994. Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol Cell Biol 14:8096-8106.
114. Saffran WA, Cantor CR, Smith ED, Magdi M. 1992. Psoralen damage-induced plasmid recombination in Saccharomyces cerevisiae: Dependence on RAD1 and RAD52. Mutat Res 274:1-9.
115. Sampath D, Plunkett W. 2007. The role of DNA repair in chronic lymphocytic leukemia pathogenesis and chemotherapy resistance. Curr Oncol Rep 9:361-367.
116. Sancar A. 1999. Excision repair invades the territory of mismatch repair. Nat Genet 21:247-249.
117. Sandor Z, Bredberg A. 1995. Triple helix directed psoralen adducts induce a low frequency of recombination in an SV-40 shuttle vector. Biochem Biophys Acta 1263:235-240.
118. Sargent RG, Rolig RL, Kilburn AE, Adair GM, Wilson JH, Nairn RS. 1997. Recombination-dependent deletion formation in mammalian cells deficient in the nucleotide excision repair gene ERCC1. Proc Natl Acad Sci USA 94:13122-13127.
119. Sarkar S, Davies AA, Ulrich HD, McHugh PJ. 2006. DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta. EMBO J 25:1285-1294.
120. Shrivastav M, De Haro LP, Nickoloff JA. 2008. Regulation of DNA double-strand break repair pathway choice. Cell Res 18:134-147.
121. Sladek FM, Munn MM, Rupp WD, Howard-Flanders P. 1989. In vitro repair of psoralen-DNA cross-links by RecA, UvrABC, and the 5′-exonuclease of DNA polymerase I. J Biol Chem 264:6755-6765.
122. Smih F, Rouet P, Romanienko PJ, Jasin M. 1995. Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells. Nucleic Acids Res 23:5012-5019.
123. Stojic L, Mojas N, Cejka P, Di Pietro M, Ferrari S, Marra G, Jiricny J. 2004. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. Genes Dev 18:1331-1344.
124. Strathern JN, Klar AJ, Hicks JB, Abraham JA, Ivy JM, Nasmyth KA, McGill C. 1982. Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus. Cell 31:183-192.
125. Svoboda DL, Taylor JS, Hearst JE, Sancar A. 1993. DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes. J Biol Chem 268:1931-1936.
126. Szostak JW, Orr-Weaver TL, Rothstein RJ, Stahl FW. 1983. The double-strand- break repair model for recombination. Cell 33:25-35.
127. Takasugi M, Guendouz A, Chassignol M, Decout JL, Lhomme J, Thuong NT, Helene C. 1991. Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide. Proc Natl Acad Sci USA 88:5602-5606.
128. Thoma BS, Wakasugi M, Christensen J, Reddy MC, Vasquez KM. 2005. Human XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks. Nucleic Acids Res 33:2993-3001.
129. Thompson LH, Hinz JM, Yamada NA, Jones NJ. 2005. How Fanconi anemia proteins promote the four Rs: Replication, recombination, repair, and recovery. Environ Mol Mutagen 45:128-142.
130. Van Houten B, Gamper H, Holbrook SR, Hearst JE, Sancar A. 1986. Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined position. Proc Natl Acad Sci USA 83:8077-8081.
131. Vasquez KM, Christensen J, Li L, Finch RA, Glazer PM. 2002. Human XPA, RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions. Proc Natl Acad Sci USA 99:5848-5853.
132. Vasquez KM, Dagle JM, Weeks DL, Glazer PM. 2001a. Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides. J Biol Chem 14:14
133. Vasquez KM, Glazer PM. 2002. Triplex-forming oligonucleotides: Principles and applications. Q Rev Biophys 35:89-107.
134. Vasquez KM, Marburger K, Intody Z, Wilson JH. 2001b. Manipulating the mammalian genome by homologous recombination. Proc Natl Acad Sci USA 98:8403-8410.
135. Vasquez KM, Narayanan L, Glazer PM. 2000. Specific mutations induced by triplex-forming oligonucleotides in mice. Science 290:530-533.
136. Vasquez KM, Wang G, Havre PA, Glazer PM. 1999. Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells. Nucleic Acids Res 27:1176-1181.
137. Vasquez KM, Wensel TG, Hogan ME, Wilson JH. 1996. High-efficiency triple-helix-mediated photo-cross-linking at a targeted site within a selectable mammalian gene. Biochemistry 35:10712-10719.
138. Wang G, Glazer PM. 1995. Altered repair of targeted psoralen photoadducts in the context of an oligonucleotide-mediated triple helix. J Biol Chem 270:22595-22601.
139. Wang G, Seidman MM, Glazer PM. 1996. Mutagen in mammalian cells induced by triple helix formation and transcription-coupled repair. Science 271:802-805.
140. Wang SQ, Setlow R, Berwick M, Polsky D, Marghoob AA, Kopf AW, Bart RS. 2001. Ultraviolet A, melanoma: A review. J Am Acad Dermatol 44:837-846.
141. Wilson DM III, Thompson LH. 2007. Molecular mechanisms of sister-chromatid exchange. Mutat Res 616:11-23.
142. Worth L Jr, Clark S, Radman M, Modrich P. 1994. Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs. Proc Natl Acad Sci USA 91:3238-3241.
143. Wu JX, Gu LY, Wang HX, Geacintov NE, Li GM. 1999. Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis. Mol Cell Biol 19:8292-8301.
144. Wu Q, Christensen LA, Legerski RJ, Vasquez KM. 2005. Mismatch repair participates in error-free processing of DNA interstrand crosslinks in human cells. EMBO Rep 6:551-557.
145. Wu Q, Vasquez KM. 2008. Human MLH1 protein participates in genomic damage checkpoint signaling in response to DNA interstrand crosslinks, while MSH2 functions in DNA repair. PLoS Genet 4:e1000189.
146. Yamada M, Oregan E, Brown R, Karran P. 1997. Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins. Nucleic Acids Res 25:491-495.
147. Yamane K, Taylor K, Kinsella TJ. 2004. Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chk1 pathway. Biochem Biophys Res Commun 318:297-302.
148. Yang W. 2006. Poor base stacking at DNA lesions may initiate recognition by many repair proteins. DNA Repair (Amst) 5:654-666.
149. 6-methylguanine adducts. Mol Cell 22:501-510.
150. Zhang N, Liu X, Li L, Legerski R. 2007. Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst) 6:1670-1678.
151. Zhang N, Lu X, Zhang X, Peterson CA, Legerski RJ. 2002. hMutS-beta is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro. Mol Cell Biol 22:2388-2397.
152. Zhao J, Jain A, Iyer RR, Modrich PL, Vasquez KM. 2009. Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks. Nucleic Acids Res 37:4420-4429.
153. Zheng H, Wang X, Legerski RJ, Glazer PM, Li L. 2006. Repair of DNA interstrand cross-links: Interactions between homology-dependent and homology-independent pathways. DNA Repair (Amst) 5:566-574.
154. Ziemba A, Derosier LC, Methvin R, Song CY, Clary E, Kahn W, Milesi D, Gorn V, Reed M, Ebbinghaus S. 2001. Repair of triplex-directed DNA alkylation by nucleotide excision repair. Nucleic Acids Res 29:4257-4263.