메뉴 건너뛰기




Volumn 355, Issue 1-2, 1996, Pages 13-40

DNA adducts from chemotherapeutic agents

Author keywords

anticancer drugs; DNA adduct; DNA cross link; DNA repair

Indexed keywords

ALKYLATING AGENT; ANTINEOPLASTIC AGENT; CARBOPLATIN; CARMUSTINE; CHLORAMBUCIL; CHLORMETHINE; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; LOMUSTINE; MELPHALAN; METHOXSALEN; MITOMYCIN; MUSTARD GAS; PROCARBAZINE;

EID: 0030591663     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(96)00020-6     Document Type: Article
Times cited : (251)

References (174)
  • 1
    • 0001005193 scopus 로고
    • Experimental and clinical studies on the treatment of cancer by dichloroethyl sulfide (mustard gas)
    • Adair, F.E. and H.J. Bagg (1931) Experimental and clinical studies on the treatment of cancer by dichloroethyl sulfide (mustard gas), Ann. Surgery, 93, 190-199.
    • (1931) Ann. Surgery , vol.93 , pp. 190-199
    • Adair, F.E.1    Bagg, H.J.2
  • 2
    • 0028087830 scopus 로고
    • Relation between platinum-DNA adducts and complete remission in adult acute nonlymphocytic leukemia
    • Armstrong, S.G., G.P. Browman, A.M. Benger, R.M. Meyer, K.L. McKay and G. Singh (1994) Relation between platinum-DNA adducts and complete remission in adult acute nonlymphocytic leukemia. Leukemia Res., 18, 659-664.
    • (1994) Leukemia Res. , vol.18 , pp. 659-664
    • Armstrong, S.G.1    Browman, G.P.2    Benger, A.M.3    Meyer, R.M.4    McKay, K.L.5    Singh, G.6
  • 3
    • 0001482314 scopus 로고
    • Synthese und abbau cytostatisch wirksamer cyclischer n-phosphamidester des bis(β-chloroäthyl)amins
    • Arnold, H. and F. Bourseaux (1958) Synthese und Abbau cytostatisch wirksamer cyclischer N-Phosphamidester des Bis(β-chloroäthyl)amins, Angew. Chem., 70, 539-544.
    • (1958) Angew. Chem. , vol.70 , pp. 539-544
    • Arnold, H.1    Bourseaux, F.2
  • 4
    • 84983711696 scopus 로고
    • Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a desoxyribonucleic acid traction isolated from pneumococcus type III
    • Avery, O.T., C.M. MacLeod and M. McCarty (1944) Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a desoxyribonucleic acid traction isolated from pneumococcus Type III, J. Exp Med., 79, 137-158.
    • (1944) J. Exp Med. , vol.79 , pp. 137-158
    • Avery, O.T.1    MacLeod, C.M.2    McCarty, M.3
  • 5
    • 0027942024 scopus 로고
    • Antibody-directed enzyme pro-drug therapy
    • Bagshawe, K.D. (1994) Antibody-directed enzyme pro-drug therapy, Clin. Pharmacother., 27, 368-376.
    • (1994) Clin. Pharmacother. , vol.27 , pp. 368-376
    • Bagshawe, K.D.1
  • 6
    • 0014885886 scopus 로고
    • DNA repair after mustard gas alkylation by sensitive and resistant Yoshida sarcoma cells in vitro
    • Ball, C.R. and J.J. Roberts (1970) DNA repair after mustard gas alkylation by sensitive and resistant Yoshida sarcoma cells in vitro, Chem.-Biol. Interactions, 2, 321-329.
    • (1970) Chem.-Biol. Interactions , vol.2 , pp. 321-329
    • Ball, C.R.1    Roberts, J.J.2
  • 7
    • 0015306214 scopus 로고
    • Estimation of interstrand DNA cross-linking resulting from mustard gas alkylation of HeLa cells
    • Ball, C.R. and J.J. Roberts (1971/72) Estimation of interstrand DNA cross-linking resulting from mustard gas alkylation of HeLa cells, Chem.-Biol. Interactions, 4, 797-303.
    • (1971) Chem.-Biol. Interactions , vol.4 , pp. 797-1303
    • Ball, C.R.1    Roberts, J.J.2
  • 8
    • 0024509419 scopus 로고
    • Chlorambucil pharmacokinetics and DNA binding in chronic lymphocytic leukemia lymphocytes
    • Bank, B.B., D. Kanganis, L.F. Liebes and R. Silber (1989) Chlorambucil pharmacokinetics and DNA binding in chronic lymphocytic leukemia lymphocytes, Cancer Res., 49, 554-559.
    • (1989) Cancer Res. , vol.49 , pp. 554-559
    • Bank, B.B.1    Kanganis, D.2    Liebes, L.F.3    Silber, R.4
  • 10
    • 0011887458 scopus 로고
    • On the dimerisation in nucleic acids as a result of ultraviolet irradiation
    • Berends, W. (1961) On the dimerisation in nucleic acids as a result of ultraviolet irradiation, J. Chem. Phys., 58, 1034-1040.
    • (1961) J. Chem. Phys. , vol.58 , pp. 1034-1040
    • Berends, W.1
  • 11
    • 37049164446 scopus 로고
    • Cyto-active amino-acid and peptide derivatives. Part I. Substituted phenylalanines
    • Bergel, F. and J.A. Stock (1954) Cyto-active amino-acid and peptide derivatives. Part I. Substituted phenylalanines, J. Chem. Soc., 2409-2417.
    • (1954) J. Chem. Soc. , pp. 2409-2417
    • Bergel, F.1    Stock, J.A.2
  • 12
    • 0027946203 scopus 로고
    • Regulation of the formation of the major diethylstilbestrol-DNA adduct and some evidence of its structure
    • Bhat, H.K., X. Han, A. Gladek and J.G. Liehr (1994) Regulation of the formation of the major diethylstilbestrol-DNA adduct and some evidence of its structure, Carcinogenesis, 15, 2137-2142.
    • (1994) Carcinogenesis , vol.15 , pp. 2137-2142
    • Bhat, H.K.1    Han, X.2    Gladek, A.3    Liehr, J.G.4
  • 13
    • 0026738906 scopus 로고
    • Genetic aspects of multidrug resistance
    • Biedler, J.L. (1992) Genetic aspects of multidrug resistance, Cancer, 70, 1799-1809.
    • (1992) Cancer , vol.70 , pp. 1799-1809
    • Biedler, J.L.1
  • 14
    • 0027527219 scopus 로고
    • Drug-induced DNA modification in buccal cells of cancer patients receiving carboplatin and cisplatin combination chemotherapy, as determined by an immunocytochemical method: Interindividual variation and correlation with disease response
    • Blommaert, F.A., C. Michael, P.M.A.B. Terheggen, F.M. Muggia, V. Kortes, J.H. Schornagel, A.A.M. Hart and L. den Engelse (1993) Drug-induced DNA modification in buccal cells of cancer patients receiving carboplatin and cisplatin combination chemotherapy, as determined by an immunocytochemical method: interindividual variation and correlation with disease response, Cancer Res., 53, 5669-5675.
    • (1993) Cancer Res. , vol.53 , pp. 5669-5675
    • Blommaert, F.A.1    Michael, C.2    Terheggen, P.M.A.B.3    Muggia, F.M.4    Kortes, V.5    Schornagel, J.H.6    Hart, A.A.M.7    Den Engelse, L.8
  • 15
    • 0028707727 scopus 로고
    • Gene-specific damage and repair of DNA adducts and cross-links
    • K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadlubar and H. Bartsch (Eds.), IARC Scientific Publication No. 125, IARC, Lyon
    • Bohr, V.A. (1994) Gene-specific damage and repair of DNA adducts and cross-links, in: K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadlubar and H. Bartsch (Eds.). DNA Adducts: Identification and Biological Significance, IARC Scientific Publication No. 125, IARC, Lyon, pp. 361-369.
    • (1994) DNA Adducts: Identification and Biological Significance , pp. 361-369
    • Bohr, V.A.1
  • 16
    • 0025360932 scopus 로고
    • Recognition between mitomycin C and specific DNA sequences for cross-link formation
    • Borowy-Borowski, H., R. Lipman and M. Tomasz (1990) Recognition between mitomycin C and specific DNA sequences for cross-link formation. Biochemistry, 29, 2999-3004.
    • (1990) Biochemistry , vol.29 , pp. 2999-3004
    • Borowy-Borowski, H.1    Lipman, R.2    Tomasz, M.3
  • 17
    • 0001408659 scopus 로고
    • Release of ultraviolet light-induced thymine dimers from DNA in E. coli K-12
    • Boyce, R.P. and P. Howard-Flanders (1964) Release of ultraviolet light-induced thymine dimers from DNA in E. coli K-12, Proc. Natl. Acad. Sci. USA, 51, 293-300.
    • (1964) Proc. Natl. Acad. Sci. USA , vol.51 , pp. 293-300
    • Boyce, R.P.1    Howard-Flanders, P.2
  • 18
    • 0011849205 scopus 로고
    • On the activation of cyclophosphamide in vivo and in vitro
    • Brock, N. and H.J. Hohorst (1963) On the activation of cyclophosphamide in vivo and in vitro, Arzneimittel-Forschung, 29, 659-661.
    • (1963) Arzneimittel-Forschung , vol.29 , pp. 659-661
    • Brock, N.1    Hohorst, H.J.2
  • 19
    • 0011845571 scopus 로고
    • Studies on the mode of action of ibenzmethyzin
    • A.M. Jelliffe and J. Marks (Eds.), Cambridge, on 22 June, 1965, sponsored by Roche Products Ltd., J. Wright & Sons, Bristol
    • Brookes, P. (1965) Studies on the mode of action of ibenzmethyzin, in: A.M. Jelliffe and J. Marks (Eds.), Natulan (Ibenzmethyzin), Report of Proceedings of a Symposium held at Downing College, Cambridge, on 22 June, 1965, sponsored by Roche Products Ltd., J. Wright & Sons, Bristol, pp. 9-12.
    • (1965) Natulan (Ibenzmethyzin), Report of Proceedings of A Symposium Held at Downing College , pp. 9-12
    • Brookes, P.1
  • 20
    • 0000130061 scopus 로고
    • The reaction of mustard gas with nucleic acids in vitro and in vivo
    • Brookes, P. and P.D. Lawley (1960) The reaction of mustard gas with nucleic acids in vitro and in vivo, Biochem. J., 77, 478-484.
    • (1960) Biochem. J. , vol.77 , pp. 478-484
    • Brookes, P.1    Lawley, P.D.2
  • 21
    • 0001253917 scopus 로고
    • The reaction of mono-and di-functional alkylating agents with nucleic acids
    • Brookes, P. and P.D. Lawley (1961) The reaction of mono-and di-functional alkylating agents with nucleic acids, Biochem. J., 80, 496-503.
    • (1961) Biochem. J. , vol.80 , pp. 496-503
    • Brookes, P.1    Lawley, P.D.2
  • 22
    • 37049045997 scopus 로고
    • Evidence for the binding of polynuclear aromatic hydrocarbons to the nucleic acids of mouse skin: Relation between carcinogenic power of hydrocarbons and their binding to DNA
    • Brookes, P. and P.D. Lawley (1964) Evidence for the binding of polynuclear aromatic hydrocarbons to the nucleic acids of mouse skin: relation between carcinogenic power of hydrocarbons and their binding to DNA, Nature (Lond.), 202, 781-784.
    • (1964) Nature (Lond.) , vol.202 , pp. 781-784
    • Brookes, P.1    Lawley, P.D.2
  • 23
    • 0011802244 scopus 로고
    • In vivo reactions of isotopically labelled alkylating agents
    • L.J. Roth (Ed.), University of Chicago Press
    • Brookes, P. and P.D. Lawley (1965) In vivo reactions of isotopically labelled alkylating agents, in: L.J. Roth (Ed.), Isotopes in Experimental Pharmacology, University of Chicago Press, pp. 403-414.
    • (1965) Isotopes in Experimental Pharmacology , pp. 403-414
    • Brookes, P.1    Lawley, P.D.2
  • 25
    • 0015611515 scopus 로고
    • Repair of DNA containing interstrand cross-links in Escherichia coli: Sequential excision and recombination
    • Cole, R.S. (1973) Repair of DNA containing interstrand cross-links in Escherichia coli: sequential excision and recombination, Proc. Natl. Acad. Sci. USA, 70, 1064-1068.
    • (1973) Proc. Natl. Acad. Sci. USA , vol.70 , pp. 1064-1068
    • Cole, R.S.1
  • 26
    • 0014009614 scopus 로고
    • Mechanism of the cytotoxic action of alkylating agents in mammalian cells and evidence for the removal of alkylated groups from deoxyribonucleic acid
    • Crathorn, A.R. and J.J. Roberts (1966) Mechanism of the cytotoxic action of alkylating agents in mammalian cells and evidence for the removal of alkylated groups from deoxyribonucleic acid, Nature (Lond.), 211, 150-153.
    • (1966) Nature (Lond.) , vol.211 , pp. 150-153
    • Crathorn, A.R.1    Roberts, J.J.2
  • 27
    • 0025048631 scopus 로고
    • Immunocytochemical analysis of in vivo DNA modification
    • den Engelse, L., J. van Benthem and E. Scherer (1990) Immunocytochemical analysis of in vivo DNA modification, Mutation Res., 233, 265-287.
    • (1990) Mutation Res. , vol.233 , pp. 265-287
    • Den Engelse, L.1    Van Benthem, J.2    Scherer, E.3
  • 30
    • 0015146551 scopus 로고
    • Reaction of 7-bromomethylbenz[α]anthracene with nucleic acids, nucleotides and nucleosides
    • Dipple, A., P. Brookes, D.S. Mackintosh and M.P. Rayman (1971) Reaction of 7-bromomethylbenz[α]anthracene with nucleic acids, nucleotides and nucleosides, Biochemistry, 10, 4323-4330.
    • (1971) Biochemistry , vol.10 , pp. 4323-4330
    • Dipple, A.1    Brookes, P.2    Mackintosh, D.S.3    Rayman, M.P.4
  • 31
    • 0020524876 scopus 로고
    • Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II)
    • Eastman, A. (1983) Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II), Biochemistry, 22, 3927-3933.
    • (1983) Biochemistry , vol.22 , pp. 3927-3933
    • Eastman, A.1
  • 32
    • 0016164754 scopus 로고
    • Experimental and clinical studies of the antitumor activity of 1-methyl-1-nitrosourea (NSC-23909)
    • Emanuel, N.M., E.M. Vermel, L.A. Ostrovskaya and N.P. Korman (1974) Experimental and clinical studies of the antitumor activity of 1-methyl-1-nitrosourea (NSC-23909), Cancer Chemother. Reports, Part 1, 58, 135-148.
    • (1974) Cancer Chemother. Reports , vol.58 , Issue.PART 1 , pp. 135-148
    • Emanuel, N.M.1    Vermel, E.M.2    Ostrovskaya, L.A.3    Korman, N.P.4
  • 33
    • 37049160509 scopus 로고
    • Aryl-2-halogenoalkylamines. Part XII. Some carboxylic derivatives of N,N-di-2-chloroethylaniline
    • Everett, J.L., J.J. Roberts and W.C.J. Ross (1953) Aryl-2-halogenoalkylamines. Part XII. Some carboxylic derivatives of N,N-di-2-chloroethylaniline, J. Chem. Soc., 2386-2392.
    • (1953) J. Chem. Soc. , pp. 2386-2392
    • Everett, J.L.1    Roberts, J.J.2    Ross, W.C.J.3
  • 35
    • 0020480510 scopus 로고
    • Detection and quantification of adducts formed upon interaction of diamminedichloroplatinum(II) with DNA, by anion-exchange chromatography after enzymatic degradation
    • Fichtinger-Schepman, A.M.J., P.M. Lohman and J. Reedijk (1982) Detection and quantification of adducts formed upon interaction of diamminedichloroplatinum(II) with DNA, by anion-exchange chromatography after enzymatic degradation, Nucleic Acids Res., 10, 5345-5356.
    • (1982) Nucleic Acids Res. , vol.10 , pp. 5345-5356
    • Fichtinger-Schepman, A.M.J.1    Lohman, P.M.2    Reedijk, J.3
  • 36
    • 0022824164 scopus 로고
    • Interactions of the antitumour drug cisplatin with DNA in vitro and in vivo
    • D. Schmähl and J.M. Kaldor (Eds.), IARC Scientific Publications No. 78, IARC, Lyon
    • Fichtinger-Schepman, A.M.J., P.H.M. Lohman and F. Berends (1986) Interactions of the antitumour drug cisplatin with DNA in vitro and in vivo, in: D. Schmähl and J.M. Kaldor (Eds.), Carcinogenicity of Alkylating Cytostatic Drugs. IARC Scientific Publications No. 78, IARC, Lyon, pp. 83-99.
    • (1986) Carcinogenicity of Alkylating Cytostatic Drugs , pp. 83-99
    • Fichtinger-Schepman, A.M.J.1    Lohman, P.H.M.2    Berends, F.3
  • 37
    • 0023185508 scopus 로고
    • Cis-diamminedichloroplatinum(II)-induced DNA adducts in peripheral leukocytes from seven cancer patients. Quantitative immunochemical detection of the adduct induction and removal after a single dose of cis-diamminedichloroplatnum(II)
    • Fichtinger-Schepman, A.M.J., A.T. van Oosterom, P.H.M. Lohman and F. Berends (1987) Cis-diamminedichloroplatinum(II)-induced DNA adducts in peripheral leukocytes from seven cancer patients. Quantitative immunochemical detection of the adduct induction and removal after a single dose of cis-diamminedichloroplatnum(II), Cancer Res., 47, 3000-3004.
    • (1987) Cancer Res. , vol.47 , pp. 3000-3004
    • Fichtinger-Schepman, A.M.J.1    Van Oosterom, A.T.2    Lohman, P.H.M.3    Berends, F.4
  • 38
    • 0025601469 scopus 로고
    • Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: Comparison with in vitro adduct formation
    • Fichtinger-Schepman, A.M.J., S.D. van der Velde-Visser, H.C.M. van Dijk-Knijnenburg, A.T. van Oosterom, R.A. Baan and F. Berends (1990) Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: comparison with in vitro adduct formation, Cancer Res., 50, 7887-7894.
    • (1990) Cancer Res. , vol.50 , pp. 7887-7894
    • Fichtinger-Schepman, A.M.J.1    Van Der Velde-Visser, S.D.2    Van Dijk-Knijnenburg, H.C.M.3    Van Oosterom, A.T.4    Baan, R.A.5    Berends, F.6
  • 39
    • 0028267005 scopus 로고
    • Synthesis, characterization, and quantitation of the major adducts formed between sulfur mustard and DNA of calf thymus and human blood
    • Fidder, A., G.W.H. Moes, A.G. Scheffer, G.P. van der Schans, R.A. Baan, L.P.A. de Jong and H.P. Benschop (1994) Synthesis, characterization, and quantitation of the major adducts formed between sulfur mustard and DNA of calf thymus and human blood, Chem. Res. Toxicol., 7, 199-204.
    • (1994) Chem. Res. Toxicol. , vol.7 , pp. 199-204
    • Fidder, A.1    Moes, G.W.H.2    Scheffer, A.G.3    Van Der Schans, G.P.4    Baan, R.A.5    De Jong, L.P.A.6    Benschop, H.P.7
  • 40
    • 0017884208 scopus 로고
    • Increased sensitivity of u.v.-repair-deficient human cells to DNA-bound platinum products which unlike thymine dimers are not recognized by an endonuclease extracted from micrococcus luteus
    • Fraval, H.N.A., C.J. Rawlings and J.J. Roberts (1978) Increased sensitivity of u.v.-repair-deficient human cells to DNA-bound platinum products which unlike thymine dimers are not recognized by an endonuclease extracted from micrococcus luteus, Mutation Res., 51, 121-132.
    • (1978) Mutation Res. , vol.51 , pp. 121-132
    • Fraval, H.N.A.1    Rawlings, C.J.2    Roberts, J.J.3
  • 44
    • 0001060019 scopus 로고
    • The biological actions and therapeutic applications of the β-chloroethyl amines and sulfides
    • Gilman, A. and F.S. Philips (1946) The biological actions and therapeutic applications of the β-chloroethyl amines and sulfides, Science, 103, 409-415.
    • (1946) Science , vol.103 , pp. 409-415
    • Gilman, A.1    Philips, F.S.2
  • 45
    • 0000075157 scopus 로고
    • Mode of production of chromosome abnormalities by nitrogen mustards: Possible role of cross-linking
    • Goldacre, R.J., Loveless, A. and Ross, W.C.J. (1949) Mode of production of chromosome abnormalities by nitrogen mustards: possible role of cross-linking, Nature (Lond.), 163, 667-669.
    • (1949) Nature (Lond.) , vol.163 , pp. 667-669
    • Goldacre, R.J.1    Loveless, A.2    Ross, W.C.J.3
  • 46
    • 0017360366 scopus 로고
    • Evidence for carrier-mediate transport of melphalan by L5178Y lymphoblasts in vitro
    • Goldenberg, G.J., M. Lee, P.H.-Y. Lam and A. Begleiter (1977) Evidence for carrier-mediate transport of melphalan by L5178Y lymphoblasts in vitro, Cancer Res., 37, 755-760.
    • (1977) Cancer Res. , vol.37 , pp. 755-760
    • Goldenberg, G.J.1    Lee, M.2    Lam, P.H.-Y.3    Begleiter, A.4
  • 48
    • 0026606580 scopus 로고
    • Induction of covalent DNA adducts in rodents by tamoxifen
    • Han, X. and Liehr, J.G. (1992) Induction of covalent DNA adducts in rodents by tamoxifen, Cancer Res., 52, 1300-1303.
    • (1992) Cancer Res. , vol.52 , pp. 1300-1303
    • Han, X.1    Liehr, J.G.2
  • 49
    • 0023234707 scopus 로고
    • Formation and removal of DNA cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells
    • Hansson, J., R. Lewensohn, U. Ringborg and B. Nilsson (1987) Formation and removal of DNA cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells, Cancer Res., 47, 2631-2637.
    • (1987) Cancer Res. , vol.47 , pp. 2631-2637
    • Hansson, J.1    Lewensohn, R.2    Ringborg, U.3    Nilsson, B.4
  • 50
    • 0028171370 scopus 로고
    • 6-methyl-and N7-methyldeoxyguanosine-3″-monophosphates in human DNA
    • 6-methyl-and N7-methyldeoxyguanosine-3″-monophosphates in human DNA, Carcinogenesis, 15, 2485-2490.
    • (1994) Carcinogenesis , vol.15 , pp. 2485-2490
    • Haque, K.1    Cooper, D.P.2    Povey, A.C.3
  • 51
    • 0022273496 scopus 로고
    • Chemical modification of DNA with muta-carcinogens. III. Reductive alkylation of DNA with mitomycin C
    • Hashimoto, Y. and Shudo, K. (1985) Chemical modification of DNA with muta-carcinogens. III. Reductive alkylation of DNA with mitomycin C, Environ. Health Perspect., 62, 219-222.
    • (1985) Environ. Health Perspect. , vol.62 , pp. 219-222
    • Hashimoto, Y.1    Shudo, K.2
  • 52
    • 0022358539 scopus 로고
    • Binding of metabolites of cyclophosphamide to DNA in a rat liver microsomal system and in vivo in mice
    • Hemminki, K. (1985) Binding of metabolites of cyclophosphamide to DNA in a rat liver microsomal system and in vivo in mice, Cancer Res., 45, 4237-4243.
    • (1985) Cancer Res. , vol.45 , pp. 4237-4243
    • Hemminki, K.1
  • 53
    • 0023101923 scopus 로고
    • DNA-binding products of nornitrogen mustard, a metabolite of cyclophosphamide
    • Hemminki, K. (1987) DNA-binding products of nornitrogen mustard, a metabolite of cyclophosphamide, Chem.-Biol. Interactions, 61, 75-88.
    • (1987) Chem.-Biol. Interactions , vol.61 , pp. 75-88
    • Hemminki, K.1
  • 54
    • 0028709432 scopus 로고
    • DNA adducts of nitrogen mustards and ethylene imines
    • K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadlubar and H. Bartsch (Eds.), IARC Scientific Publication No. 125, IARC, Lyon
    • Hemminki, K. (1994) DNA adducts of nitrogen mustards and ethylene imines, in: K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadlubar and H. Bartsch (Eds.), DNA Adducts: Identification and Biological Significance, IARC Scientific Publication No. 125, IARC, Lyon, pp. 313-321.
    • (1994) DNA Adducts: Identification and Biological Significance , pp. 313-321
    • Hemminki, K.1
  • 55
    • 0025195890 scopus 로고
    • 32P-post-labelling of 7-methyl-dGMP, ring-opened 7-methyl-dGMP and platinated dGpG
    • 32P-post-labelling of 7-methyl-dGMP, ring-opened 7-methyl-dGMP and platinated dGpG, Chem.-Biol. Interactions, 74, 45-54.
    • (1990) Chem.-Biol. Interactions , vol.74 , pp. 45-54
    • Hemminki, K.1    Peltonen, K.2    Mustonen, R.3
  • 57
    • 0018967709 scopus 로고
    • Methylated purines in human liver after probable dimethyinitosamine
    • Herron, D.C. and R.C. Shank (1980) Methylated purines in human liver after probable dimethyinitosamine, Cancer Res., 40, 3116-3117.
    • (1980) Cancer Res. , vol.40 , pp. 3116-3117
    • Herron, D.C.1    Shank, R.C.2
  • 58
    • 0026024072 scopus 로고
    • Sequence preferences of DNA interstrand cross-linking agents: Importance of minimal DNA structural reorganization in the cross-linking reactions of mechlorethamine, cisptatin, and mitomycin C
    • Hopkins, P.B., J.T. Millard, J. Woo, M.F. Weidner, J.J. Kirchner, S.T. Sigurdsson and S. Raucher (1991) Sequence preferences of DNA interstrand cross-linking agents: importance of minimal DNA structural reorganization in the cross-linking reactions of mechlorethamine, cisptatin, and mitomycin C, Tetrahedron, 47, 2475-2489.
    • (1991) Tetrahedron , vol.47 , pp. 2475-2489
    • Hopkins, P.B.1    Millard, J.T.2    Woo, J.3    Weidner, M.F.4    Kirchner, J.J.5    Sigurdsson, S.T.6    Raucher, S.7
  • 59
    • 0027944087 scopus 로고
    • Substrate spectrum of human exinuclease repair of abasic sites, methylated bases, mismatches, and bulky adducts
    • Huang, J.-C., D.S. Hsu, A. Kazantsev and A. Sancar (1994) Substrate spectrum of human exinuclease repair of abasic sites, methylated bases, mismatches, and bulky adducts, Proc. Natl. Acad. Sci. USA, 91, 12213-12217.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12213-12217
    • Huang, J.-C.1    Hsu, D.S.2    Kazantsev, A.3    Sancar, A.4
  • 60
    • 78651117965 scopus 로고
    • A molecular mechanism of mitomycin action: Linking of complementary DNA strands
    • Iyer, V.N. and W. Szybalski (1963) A molecular mechanism of mitomycin action: linking of complementary DNA strands, Proc. Natl. Acad. Sci. USA, 50, 355-362.
    • (1963) Proc. Natl. Acad. Sci. USA , vol.50 , pp. 355-362
    • Iyer, V.N.1    Szybalski, W.2
  • 61
    • 0002548343 scopus 로고
    • Mitomycins and porfiromycin; chemical mechanisms of activation and cross-linking of DNA
    • Iyer, V.N. and W. Szybalski (1964) Mitomycins and porfiromycin; chemical mechanisms of activation and cross-linking of DNA, Science, 145, 55-58.
    • (1964) Science , vol.145 , pp. 55-58
    • Iyer, V.N.1    Szybalski, W.2
  • 62
    • 0018725970 scopus 로고
    • Isolation and characterization of E. coli K12 mutants unable to induce the adaptive response to simple alkylating agents
    • Jeggo, P. (1979) Isolation and characterization of E. coli K12 mutants unable to induce the adaptive response to simple alkylating agents, J. Bacteriol., 139, 783-791.
    • (1979) J. Bacteriol. , vol.139 , pp. 783-791
    • Jeggo, P.1
  • 64
    • 0028533694 scopus 로고
    • DNA damage tolerance, mismatch repair and genome instability
    • Karran, P. and M. Bignami (1994) DNA damage tolerance, mismatch repair and genome instability, BioEssays, 16, 833-839.
    • (1994) BioEssays , vol.16 , pp. 833-839
    • Karran, P.1    Bignami, M.2
  • 65
    • 0019173806 scopus 로고
    • Escherichia coli mutants deficient in 3-methyladenine-DNA glycosylase
    • Karran, P., T. Lindahl, I. Øfsteng, G.B. Evenson and E. Seeberg (1980) Escherichia coli mutants deficient in 3-methyladenine-DNA glycosylase, J. Mol. Biol., 140, 101-127.
    • (1980) J. Mol. Biol. , vol.140 , pp. 101-127
    • Karran, P.1    Lindahl, T.2    Evenson, G.B.3    Seeberg, E.4
  • 66
    • 0027973570 scopus 로고
    • Resistance to antitumor agent-induced apoptosis in a mutant of human myeloid leukemia U937 cells
    • Kataoka, S., M. Naito, A. Toida and T. Tsuruo (1994) Resistance to antitumor agent-induced apoptosis in a mutant of human myeloid leukemia U937 cells, Exp. Cell Res., 215, 199-205.
    • (1994) Exp. Cell Res. , vol.215 , pp. 199-205
    • Kataoka, S.1    Naito, M.2    Toida, A.3    Tsuruo, T.4
  • 68
    • 0022457418 scopus 로고
    • Mechanism of cytotoxicity of anticancer platinum drugs: Evidence that cis-diamminedichloroplatinum(II) and cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA
    • Knox, R.J., F. Friedlos, D.A. Lydall and J.J. Roberts (1986) Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA, Cancer Res., 46, 1972-1979.
    • (1986) Cancer Res. , vol.46 , pp. 1972-1979
    • Knox, R.J.1    Friedlos, F.2    Lydall, D.A.3    Roberts, J.J.4
  • 69
    • 0025989352 scopus 로고
    • The Walker 256 carcinoma: A cell type inherently sensitive only to those difunctional agents that can form DNA interstrand crosslinks
    • Knox, R.J., D.A. Lydall, F. Friedlos, C. Basham, C.J. Rawlings and J.J. Roberts (1991) The Walker 256 carcinoma: a cell type inherently sensitive only to those difunctional agents that can form DNA interstrand crosslinks, Mutation Res., 255, 227-240.
    • (1991) Mutation Res. , vol.255 , pp. 227-240
    • Knox, R.J.1    Lydall, D.A.2    Friedlos, F.3    Basham, C.4    Rawlings, C.J.5    Roberts, J.J.6
  • 70
    • 0028277306 scopus 로고
    • Detection of platinum-DNA adducts in cord blood lymphocytes following in utero platinum exposure
    • Koc, O.N., M. McFee, E. Reed and S.L. Gerson (1994) Detection of platinum-DNA adducts in cord blood lymphocytes following in utero platinum exposure, Eur. J. Cancer, 30A, 716-717.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 716-717
    • Koc, O.N.1    McFee, M.2    Reed, E.3    Gerson, S.L.4
  • 71
    • 0014170671 scopus 로고
    • Alkylated DNA: Buoyant density changes and modes of decomposition
    • Kohn, K.W. and C.L. Spears (1967) Alkylated DNA: buoyant density changes and modes of decomposition, Biochim. Biophys. Acta, 145, 720-733.
    • (1967) Biochim. Biophys. Acta , vol.145 , pp. 720-733
    • Kohn, K.W.1    Spears, C.L.2
  • 72
    • 0013782386 scopus 로고
    • Cross-linking and repair of DNA in sensitive and resistant strains of E. coli treated with nitrogen mustard
    • Kohn, K.W., N.H. Steigbigel and C.L. Spears (1965) Cross-linking and repair of DNA in sensitive and resistant strains of E. coli treated with nitrogen mustard, Proc. Natl. Acad. Sci. USA, 53, 1154-1161.
    • (1965) Proc. Natl. Acad. Sci. USA , vol.53 , pp. 1154-1161
    • Kohn, K.W.1    Steigbigel, N.H.2    Spears, C.L.3
  • 73
    • 0013936069 scopus 로고
    • Interstrand cross-linking of DNA by nitrogen mustard
    • Kohn, K.W., C.L. Spears and P. Doty (1966) Interstrand cross-linking of DNA by nitrogen mustard, J. Mol. Biol., 19, 266-288.
    • (1966) J. Mol. Biol. , vol.19 , pp. 266-288
    • Kohn, K.W.1    Spears, C.L.2    Doty, P.3
  • 74
    • 0017754850 scopus 로고
    • Combination chemotherapy with 1-methyl-1-nitrosourea (MNU) and cyclophosphamide in solid tumours
    • Kolaric', K. (1977) Combination chemotherapy with 1-methyl-1-nitrosourea (MNU) and cyclophosphamide in solid tumours, Z. Krebsforschung, 89, 311-319.
    • (1977) Z. Krebsforschung , vol.89 , pp. 311-319
    • Kolaric', K.1
  • 75
    • 0001412401 scopus 로고
    • The blood and bone marrow in yellow cross gas (mustard gas) poisoning: Changes produced in the bone marrow of fatal cases
    • Krumbhaar, E.B. and H.D. Krumbhaar (1919) The blood and bone marrow in yellow cross gas (mustard gas) poisoning: changes produced in the bone marrow of fatal cases, J. Med. Res., 40, 497-507.
    • (1919) J. Med. Res. , vol.40 , pp. 497-507
    • Krumbhaar, E.B.1    Krumbhaar, H.D.2
  • 77
    • 0000785768 scopus 로고
    • Carcinogenesis by alkylating agents
    • C.E.Searle (Ed.), ACS Monograph 182, American Chemical Society, Washington
    • Lawley, P.D. (1984) Carcinogenesis by alkylating agents, in: C.E.Searle (Ed.) Chemical carcinogens, 2nd Edn., Vol. 1, ACS Monograph 182, American Chemical Society, Washington, pp. 325-484.
    • (1984) Chemical Carcinogens, 2nd Edn. , vol.1 , pp. 325-484
    • Lawley, P.D.1
  • 79
    • 0000380355 scopus 로고
    • Molecular mechanism of cytotoxic action of difunctional alkylating agents and of resistance to this action
    • Lawley, P.D. and P. Brookes (1965) Molecular mechanism of cytotoxic action of difunctional alkylating agents and of resistance to this action. Nature (Lond.), 206, 480-483.
    • (1965) Nature (Lond.) , vol.206 , pp. 480-483
    • Lawley, P.D.1    Brookes, P.2
  • 80
    • 0014336604 scopus 로고
    • Cytotoxicity of alkylating agents towards sensitive and resistant strains of Escherichia coli in relation to extent and mode of alkyiation of cellular macromolecules and repair of alkyiation lesions in DNA
    • Lawley, P.D. and P. Brookes (1968) Cytotoxicity of alkylating agents towards sensitive and resistant strains of Escherichia coli in relation to extent and mode of alkyiation of cellular macromolecules and repair of alkyiation lesions in DNA. Biochem. J., 109, 433-447.
    • (1968) Biochem. J. , vol.109 , pp. 433-447
    • Lawley, P.D.1    Brookes, P.2
  • 81
    • 0014826833 scopus 로고
    • Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N″-nitro-N-nitrosoguanidine
    • Lawley, P.D. and D.J. Orr (1970) Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N″-nitro-N-nitrosoguanidine, Chem.-Biol. Interactions, 2, 154-157.
    • (1970) Chem.-Biol. Interactions , vol.2 , pp. 154-157
    • Lawley, P.D.1    Orr, D.J.2
  • 82
    • 0015400298 scopus 로고
    • Reaction of alkylating mutagens and carcinogens with nucleic acids: Detection and estimation of a small extent of methylation at O-6 of guanine in DNA by methyl methanesulfonate in vitro
    • Lawley, P.D. and S.A. Shah (1972) Reaction of alkylating mutagens and carcinogens with nucleic acids: detection and estimation of a small extent of methylation at O-6 of guanine in DNA by methyl methanesulfonate in vitro, Chem.-Biol. Interactions, 5, 286-288.
    • (1972) Chem.-Biol. Interactions , vol.5 , pp. 286-288
    • Lawley, P.D.1    Shah, S.A.2
  • 83
    • 0015698785 scopus 로고
    • 14C-methyl-labelled N-methyl-N-nitrosourea: Evidence for transfer of the intact methyl group
    • 14C-methyl-labelled N-methyl-N-nitrosourea: evidence for transfer of the intact methyl group, Chem.-Biol. Interactions, 7, 115-120.
    • (1973) Chem.-Biol. Interactions , vol.7 , pp. 115-120
    • Lawley, P.D.1    Shah, S.A.2
  • 84
    • 0014733394 scopus 로고
    • Methylation of DNA in cultured mammalian cells by N-melthyl-N″-nitro-N-nitrosoguanidine: The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation
    • Lawley, P.D. and C.J. Thatcher (1970) Methylation of DNA in cultured mammalian cells by N-melthyl-N″-nitro-N-nitrosoguanidine: the influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation, Biochem. J., 116, 693-707.
    • (1970) Biochem. J. , vol.116 , pp. 693-707
    • Lawley, P.D.1    Thatcher, C.J.2
  • 85
    • 0014674093 scopus 로고
    • Inactivation of bacteriophage T7 by mono-and di-functional sulphur mustards in relation to cross-linking and depurination of bacteriophage DNA
    • Lawley, P.D., J.H. Lethbridge, P.A. Edwards and K.V. Shooter (1969) Inactivation of bacteriophage T7 by mono-and di-functional sulphur mustards in relation to cross-linking and depurination of bacteriophage DNA, J. Mol. Biol., 39, 181-198.
    • (1969) J. Mol. Biol. , vol.39 , pp. 181-198
    • Lawley, P.D.1    Lethbridge, J.H.2    Edwards, P.A.3    Shooter, K.V.4
  • 88
    • 0014672640 scopus 로고
    • 6-alkylation of deoxyguanosine to mutagenicity and carcinogenicity of nitrosamines and nitrosamides
    • 6-alkylation of deoxyguanosine to mutagenicity and carcinogenicity of nitrosamines and nitrosamides, Nature (Lond.), 223, 206-207.
    • (1969) Nature (Lond.) , vol.223 , pp. 206-207
    • Loveless, A.1
  • 89
    • 0022832560 scopus 로고
    • Nature and biological significance of DNA modification by the haloethylnitrosoureas
    • D. Schmähl and J.M. Kaldor (Eds.), IARC Scientific Publication No, 78, IARC, Lyon
    • Ludlum, D.B. (1986) Nature and biological significance of DNA modification by the haloethylnitrosoureas, in: D. Schmähl and J.M. Kaldor (Eds.), Carcinogenicity of Alkylating Cytostatic Drugs, IARC Scientific Publication No, 78, IARC, Lyon, pp. 71-81.
    • (1986) Carcinogenicity of Alkylating Cytostatic Drugs , pp. 71-81
    • Ludlum, D.B.1
  • 93
    • 0020586753 scopus 로고
    • Binding of platinum compounds to nucleic acids with respect to the anti-tumor activity of cis-diamminedichloroplatinum(II) and derivatives
    • Marcelis, A.T.M. and J. ReediJk (1983) Binding of platinum compounds to nucleic acids with respect to the anti-tumor activity of cis-diamminedichloroplatinum(II) and derivatives, Rec. Trav. Chim. Pays Bas, 102, 121-129.
    • (1983) Rec. Trav. Chim. Pays Bas , vol.102 , pp. 121-129
    • Marcelis, A.T.M.1    Reedijk, J.2
  • 94
    • 0028690470 scopus 로고
    • DNA adducts of α,β-unsaturated aldehydes and dicarbonyl compounds
    • K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadlubar, D. Segerback and H. Bartsch (Eds.), IARC Scientific Publication No. 125, IARC, Lyon
    • Marnett, L.J. (1994) DNA adducts of α,β-unsaturated aldehydes and dicarbonyl compounds, in: K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadlubar, D. Segerback and H. Bartsch (Eds.), DNA Adducts: Identification and Biological Significance, IARC Scientific Publication No. 125, IARC, Lyon, pp. 151-163.
    • (1994) DNA Adducts: Identification and Biological Significance , pp. 151-163
    • Marnett, L.J.1
  • 95
    • 0025729206 scopus 로고
    • Evidence for acrolein-modified DNA in peripheral blood leukocytes of cancer patients treated with cyclophosphamide
    • McDiarmid, M.A., P.T. Iype, K. Kolodner, D. Jacobson-Kram and P.T. Strickland (1991) Evidence for acrolein-modified DNA in peripheral blood leukocytes of cancer patients treated with cyclophosphamide, Mutation Res., 248, 93-99.
    • (1991) Mutation Res. , vol.248 , pp. 93-99
    • McDiarmid, M.A.1    Iype, P.T.2    Kolodner, K.3    Jacobson-Kram, D.4    Strickland, P.T.5
  • 97
    • 0023251155 scopus 로고
    • Comparison of melphalan toxicity in human lymphocytic cells and Chinese hamster cells in vitro: The relationship between DNA-DNA crosslink formation and clonogenic survival
    • Millar, B.C., and J.B.G. Bell (1987) Comparison of melphalan toxicity in human lymphocytic cells and Chinese hamster cells in vitro: the relationship between DNA-DNA crosslink formation and clonogenic survival, Carcinogenesis, 8, 1225-1229.
    • (1987) Carcinogenesis , vol.8 , pp. 1225-1229
    • Millar, B.C.1    Bell, J.B.G.2
  • 98
    • 0024360542 scopus 로고
    • Melphalan transport into human malignant lymphoid cells differs from the murine equivalent in vitro
    • Millar, B.C., J.A. Maitland, J.L. Millar and J.B.G. Bell (1989) Melphalan transport into human malignant lymphoid cells differs from the murine equivalent in vitro, Br. J. Cancer, 59, 710-713.
    • (1989) Br. J. Cancer , vol.59 , pp. 710-713
    • Millar, B.C.1    Maitland, J.A.2    Millar, J.L.3    Bell, J.B.G.4
  • 99
    • 0026779664 scopus 로고
    • Identifiication of cyclophosphamide-DNA adducts in rat embryos exposed in vitro to 4-hydroperoxycyclophosphamide
    • Mirkes, P.E., N.A. Brown, M. KaJbaf, J.H. Lamb, P.B. Farmer and S. Naylor (1992) Identifiication of cyclophosphamide-DNA adducts in rat embryos exposed in vitro to 4-hydroperoxycyclophosphamide, Chem. Res. Toxicol., 5, 382-385.
    • (1992) Chem. Res. Toxicol. , vol.5 , pp. 382-385
    • Mirkes, P.E.1    Brown, N.A.2    KaJbaf, M.3    Lamb, J.H.4    Farmer, P.B.5    Naylor, S.6
  • 100
    • 0026610238 scopus 로고
    • 6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation
    • 6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation, Cancer Res., 52, 1171-1175.
    • (1992) Cancer Res. , vol.52 , pp. 1171-1175
    • Mitchell, R.B.1    Moschel, R.C.2    Dolan, M.E.3
  • 101
    • 0027431040 scopus 로고
    • Quantification of sulfur-mustard-induced cross-links and single-strand breaks in cultured human epidermal keratinocytes
    • Mol, M.A.E., G.P. van der Schans and P.H.M. Lohman (1993) Quantification of sulfur-mustard-induced cross-links and single-strand breaks in cultured human epidermal keratinocytes, Mutation Res., 294, 235-245.
    • (1993) Mutation Res. , vol.294 , pp. 235-245
    • Mol, M.A.E.1    Van Der Schans, G.P.2    Lohman, P.H.M.3
  • 102
    • 0028359246 scopus 로고
    • Platinum-DNA adducts assayed in leukocytes of patients with germ cell tumors measured by atomic absorbance spectrometry and enzyme-linked immunosorbent assay
    • Motzer, R.J., E. Reed, F. Perera, D. Tang, H. Shamkhani, M.C. Poirier, W.-Y. Tsai, R.J. Parker and G.J. Bosl (1994) Platinum-DNA adducts assayed in leukocytes of patients with germ cell tumors measured by atomic absorbance spectrometry and enzyme-linked immunosorbent assay, Cancer 73, 2843-2852.
    • (1994) Cancer , vol.73 , pp. 2843-2852
    • Motzer, R.J.1    Reed, E.2    Perera, F.3    Tang, D.4    Shamkhani, H.5    Poirier, M.C.6    Tsai, W.-Y.7    Parker, R.J.8    Bosl, G.J.9
  • 103
    • 0025923492 scopus 로고
    • 32P-postlabelling of 7-methylguanine levels in white blood cell DNA of healthy individuals and cancer patients treated with dacarbazine and procarbazine. Human data and method development for 7-alkylguanines
    • 32P-postlabelling of 7-methylguanine levels in white blood cell DNA of healthy individuals and cancer patients treated with dacarbazine and procarbazine. Human data and method development for 7-alkylguanines, Carcinogenesis, 12, 1423-1431.
    • (1991) Carcinogenesis , vol.12 , pp. 1423-1431
    • Mustonen, R.1    Försti, A.2    Hietanen, P.3    Hemminki, K.4
  • 104
    • 0024355567 scopus 로고
    • Synthesis of a duplex oligonucleotide containing a nitrogen mustard interstrand DNA-DNA cross-link
    • Ojwang, J.O., D.A. Gruenberg and E.L. Loechler (1989) Synthesis of a duplex oligonucleotide containing a nitrogen mustard interstrand DNA-DNA cross-link. Cancer Res., 49, 6529-6537.
    • (1989) Cancer Res. , vol.49 , pp. 6529-6537
    • Ojwang, J.O.1    Gruenberg, D.A.2    Loechler, E.L.3
  • 105
    • 0019211791 scopus 로고
    • Repair of alkylated DNA in Escherichia coli
    • Olsson, M. and T. Lindahl (1980) Repair of alkylated DNA in Escherichia coli, J. Biol. Chem., 255, 10569-10571.
    • (1980) J. Biol. Chem. , vol.255 , pp. 10569-10571
    • Olsson, M.1    Lindahl, T.2
  • 106
    • 0027514969 scopus 로고
    • Alkylation of DNA by melphalan with special reference to adenine derivatives and adenine-guanine cross-linking
    • Osborne, M.R. and P.D. Lawley (1993) Alkylation of DNA by melphalan with special reference to adenine derivatives and adenine-guanine cross-linking, Chem.-Biol. Interactions. 89. 49-60.
    • (1993) Chem.-Biol. Interactions , vol.89 , pp. 49-60
    • Osborne, M.R.1    Lawley, P.D.2
  • 107
    • 0028943798 scopus 로고
    • Alkylation of DNA by the nitrogen mustard bis(2-chloroethyl)methylamine
    • Osborne, M.R., D.E.V. Wilman and P.D. Lawley (I995a) Alkylation of DNA by the nitrogen mustard bis(2-chloroethyl)methylamine, Chem. Res. Toxicol., 8, 316-320.
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 316-320
    • Osborne, M.R.1    Wilman, D.E.V.2    Lawley, P.D.3
  • 108
    • 0029119506 scopus 로고
    • Products from alkylation of DNA in cells by melphalan: Human soft tissue sarcoma cell line RD and Escherichia coli WP2
    • Osborne, M.R., P.D. Lawley, C. Crofton-Sleigh and W. Warren (1995b) Products from alkylation of DNA in cells by melphalan: human soft tissue sarcoma cell line RD and Escherichia coli WP2, Chem.-Biol. Interactions, 97, 287-296.
    • (1995) Chem.-Biol. Interactions , vol.97 , pp. 287-296
    • Osborne, M.R.1    Lawley, P.D.2    Crofton-Sleigh, C.3    Warren, W.4
  • 110
    • 0026522291 scopus 로고
    • Repair of DNA containing O6-alkylguanine
    • Pegg, A.E. and T.L. Byers (1992) Repair of DNA containing O6-alkylguanine, FASEB J., 6, 2302-2310.
    • (1992) FASEB J. , vol.6 , pp. 2302-2310
    • Pegg, A.E.1    Byers, T.L.2
  • 111
    • 0021358152 scopus 로고
    • Induction and repair of DNA cross-links in Chinese hamster ovary cells treated with various pfatium coordination compounds in relation to platinum binding to DNA, cytotoxicity, mutagenicity, and antitumor activity
    • Plooy, A.C.M., M. van Dijk and P.H.M. Lohman (1984) Induction and repair of DNA cross-links in Chinese hamster ovary cells treated with various pfatium coordination compounds in relation to platinum binding to DNA, cytotoxicity, mutagenicity, and antitumor activity, Cancer Res., 44, 2043-2051.
    • (1984) Cancer Res. , vol.44 , pp. 2043-2051
    • Plooy, A.C.M.1    Van Dijk, M.2    Lohman, P.H.M.3
  • 113
    • 0023065521 scopus 로고
    • DNA adducts of cisplatin in nucleated peripheral blood cells and tissues of cancer patients
    • Poirier, M.C., E. Reed, R.F. Ozols, T. Fasy and S.H. Yuspa (1987) DNA adducts of cisplatin in nucleated peripheral blood cells and tissues of cancer patients. Prog. Exp. Tumor Res., 31, 104-113.
    • (1987) Prog. Exp. Tumor Res. , vol.31 , pp. 104-113
    • Poirier, M.C.1    Reed, E.2    Ozols, R.F.3    Fasy, T.4    Yuspa, S.H.5
  • 115
    • 0027168453 scopus 로고
    • Platinum-DNA interactions in human tissues measured by cisplatin DNA enzyme-linked immunosorbent assay and atomic absorbance spectroscopy
    • Poirier, M.C., E. Reed, H. Shamkhani, R.E. Tarone and S. Gupta-Burt (1993) Platinum-DNA interactions in human tissues measured by cisplatin DNA enzyme-linked immunosorbent assay and atomic absorbance spectroscopy, Environ. Health Perspect., 99, 149-154.
    • (1993) Environ. Health Perspect. , vol.99 , pp. 149-154
    • Poirier, M.C.1    Reed, E.2    Shamkhani, H.3    Tarone, R.E.4    Gupta-Burt, S.5
  • 116
    • 0014439911 scopus 로고
    • Mechanism of carcinogenesis with 1-aryl-3,3-dialkyltriazenes. Enzymatic dealkylation by rat liver microsomal fraction in vitro
    • Preussmann, R., A. Von Hodenberg and H. Hengy (1969) Mechanism of carcinogenesis with 1-aryl-3,3-dialkyltriazenes. Enzymatic dealkylation by rat liver microsomal fraction in vitro, Biochem. Pharmacol., 18, 1-13.
    • (1969) Biochem. Pharmacol. , vol.18 , pp. 1-13
    • Preussmann, R.1    Von Hodenberg, A.2    Hengy, H.3
  • 117
    • 0023161374 scopus 로고
    • 32P-analysis of DNA adducts in somatic and reproductive tissues of rats treated with the anticancer antibiotic, mitomycin C
    • 32P-Analysis of DNA adducts in somatic and reproductive tissues of rats treated with the anticancer antibiotic, mitomycin C, Mutation Res., 179, 75-88.
    • (1987) Mutation Res. , vol.179 , pp. 75-88
    • Reddy, M.V.1    Randerath, K.2
  • 118
    • 0026314718 scopus 로고
    • Alkylating agents and platinum: Is clinical resistance simply a tumor cell phenomenon?
    • Reed, E. (1991) Alkylating agents and platinum: is clinical resistance simply a tumor cell phenomenon? Current Opininon in Oncology, 3, 1055-1059.
    • (1991) Current Opininon in Oncology , vol.3 , pp. 1055-1059
    • Reed, E.1
  • 119
    • 0022553245 scopus 로고
    • Quantitation of cisplatin-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy
    • Reed, E., S.H. Yuspa, L.A. Zwelling, R.F. Ozols and M.C. Poirier (1986) Quantitation of cisplatin-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy, J. Clin. Invest., 77, 545-550.
    • (1986) J. Clin. Invest. , vol.77 , pp. 545-550
    • Reed, E.1    Yuspa, S.H.2    Zwelling, L.A.3    Ozols, R.F.4    Poirier, M.C.5
  • 120
    • 0002963473 scopus 로고
    • Quantitation of platinum-DNA binding after therapeutic levels of drug exposure - A novel use of graphite furnace spectrometry
    • Reed, E., S. Sauerhoff and M.C. Poirier (1988) Quantitation of platinum-DNA binding after therapeutic levels of drug exposure - a novel use of graphite furnace spectrometry, Atomic Spectroscopy, 9, 93-95.
    • (1988) Atomic Spectroscopy , vol.9 , pp. 93-95
    • Reed, E.1    Sauerhoff, S.2    Poirier, M.C.3
  • 121
    • 0025641045 scopus 로고
    • Characterization of the DNA damage recognized by an antiserum elicited against cis-diamminedichloroplatinum(II)-modified DNA
    • Reed, E., S. Gupta-Burt, C.L. Litterst and M.C. Poirier (1990) Characterization of the DNA damage recognized by an antiserum elicited against cis-diamminedichloroplatinum(II)-modified DNA, Carcinogenesis, 11, 2117-2121.
    • (1990) Carcinogenesis , vol.11 , pp. 2117-2121
    • Reed, E.1    Gupta-Burt, S.2    Litterst, C.L.3    Poirier, M.C.4
  • 122
    • 0014682978 scopus 로고
    • The response of mammalian cells to alkylattng agents II. On the mechanism of the removal of sulfur-mustard-induced crosslinks
    • Reid, B.D. and I.G. Walker (1969) The response of mammalian cells to alkylattng agents II. On the mechanism of the removal of sulfur-mustard-induced crosslinks, Biochim. Biophys. Acta, 179, 179-188.
    • (1969) Biochim. Biophys. Acta , vol.179 , pp. 179-188
    • Reid, B.D.1    Walker, I.G.2
  • 123
    • 0027159566 scopus 로고
    • Covalent structure of a nitrogen-mustard-induced DNA interstrand crosslink: An N7-to-N7 linkage of deoxyguanosine residues at the duplex sequence 5″-d(GNC)
    • Rink, S.M., M.S. Solomon, M.J. Taylor, S.B. Rajur, L.W. McLaughlin and P.B. Hopkins (1993) Covalent structure of a nitrogen-mustard-induced DNA interstrand crosslink: an N7-to-N7 linkage of deoxyguanosine residues at the duplex sequence 5″-d(GNC), J. Am. Chem. Soc., 115, 2551-2557.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 2551-2557
    • Rink, S.M.1    Solomon, M.S.2    Taylor, M.J.3    Rajur, S.B.4    McLaughlin, L.W.5    Hopkins, P.B.6
  • 124
    • 0020082088 scopus 로고
    • The frequency of interstrand cross-links in DNA following reaction of cis-diammine-dichloroplatinum(II) with cells in culture or DNA in vitro: Stability of DNA cross-links and their repair
    • Roberts, J.J. and F. Friedlos (1982) The frequency of interstrand cross-links in DNA following reaction of cis-diammine-dichloroplatinum(II) with cells in culture or DNA in vitro: stability of DNA cross-links and their repair, Chem.-Biol. Interactions, 39, 181-189.
    • (1982) Chem.-Biol. Interactions , vol.39 , pp. 181-189
    • Roberts, J.J.1    Friedlos, F.2
  • 125
    • 0015493364 scopus 로고
    • Cross-linking of complementary strands of DNA in mammalian cells by antitumour platinum compounds
    • Roberts, J.J. and J.M. Pascoe (1972) Cross-linking of complementary strands of DNA in mammalian cells by antitumour platinum compounds, Nature (Lond.), 235, 282-284.
    • (1972) Nature (Lond.) , vol.235 , pp. 282-284
    • Roberts, J.J.1    Pascoe, J.M.2
  • 127
    • 0015182304 scopus 로고
    • Evidence for the inactivation and repair of the mammalian DNA template after alkylation by mustard gas and half mustard gas
    • Roberts, J.J., T.P. Brent and A.R. Crathorn (1971a) Evidence for the inactivation and repair of the mammalian DNA template after alkylation by mustard gas and half mustard gas, Eur. J. Cancer, 7, 515-524.
    • (1971) Eur. J. Cancer , vol.7 , pp. 515-524
    • Roberts, J.J.1    Brent, T.P.2    Crathorn, A.R.3
  • 128
    • 0015008174 scopus 로고
    • Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells I. The effect on hela and Chinese hamster cell survival of alkylation of cellular macromolecules
    • Roberts, J.J., J.M. Pascoe, J.E. Plant, J.E. Sturrock and A.R. Crathorn (1971b) Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells I. The effect on HeLa and Chinese hamster cell survival of alkylation of cellular macromolecules, Chem.-Biol. Interactions, 3, 29-47.
    • (1971) Chem.-Biol. Interactions , vol.3 , pp. 29-47
    • Roberts, J.J.1    Pascoe, J.M.2    Plant, J.E.3    Sturrock, J.E.4    Crathorn, A.R.5
  • 129
    • 0022966975 scopus 로고
    • The unique sensitivity of Walker rat tumour cells to difunctional agents is associated with a failure to recover from inhibition of DNA synthesis and increased chromosome damage
    • Roberts, J.J., F. Friedlos, D. Scott, M.G. Ormerod and C.J. Rawlings (1986) The unique sensitivity of Walker rat tumour cells to difunctional agents is associated with a failure to recover from inhibition of DNA synthesis and increased chromosome damage. Mutation Res., 166, 169-181.
    • (1986) Mutation Res. , vol.166 , pp. 169-181
    • Roberts, J.J.1    Friedlos, F.2    Scott, D.3    Ormerod, M.G.4    Rawlings, C.J.5
  • 130
    • 0022403498 scopus 로고
    • Verapamil potentiation of melphalan cytotoxicity and cellular uptake in murine fibrosarcoma and bone marrow
    • Robinson, B.A., R.D. Clutterbuck, J.L. Millar and T.J. McElwain (1985) Verapamil potentiation of melphalan cytotoxicity and cellular uptake in murine fibrosarcoma and bone marrow, Br. J. Cancer, 52, 813-822.
    • (1985) Br. J. Cancer , vol.52 , pp. 813-822
    • Robinson, B.A.1    Clutterbuck, R.D.2    Millar, J.L.3    McElwain, T.J.4
  • 131
    • 0022001780 scopus 로고
    • Fundamental studies with cisplatin
    • Rosenberg, B. (1985) Fundamental studies with cisplatin, Cancer, 55, 2303-2316.
    • (1985) Cancer , vol.55 , pp. 2303-2316
    • Rosenberg, B.1
  • 132
    • 37049053957 scopus 로고
    • Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode
    • Rosenberg, B., L. van Camp and T. Krigas (1965) Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode, Nature (Lond.). 205, 698-699.
    • (1965) Nature (Lond.) , vol.205 , pp. 698-699
    • Rosenberg, B.1    Van Camp, L.2    Krigas, T.3
  • 133
    • 0020341190 scopus 로고
    • Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction
    • Rydberg, B. and T. Lindahl (1982) Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction, EMBO J., 1, 211-216.
    • (1982) EMBO J. , vol.1 , pp. 211-216
    • Rydberg, B.1    Lindahl, T.2
  • 136
    • 0345245642 scopus 로고
    • The development of high dose melphalan and of autologous bone marrow transplantation in the treatment of multiple myeloma: Royal Marsden and St Bartholomew's Hospital studies
    • Selby, P.J., G. Zulian, G. Forgeson, A.C. Nardi, S. Milan, M. Meldrum, C. Viner, R.J. Osborne, J.S. Malpas and T.J. McElwain (1988) The development of high dose melphalan and of autologous bone marrow transplantation in the treatment of multiple myeloma: Royal Marsden and St Bartholomew's Hospital studies, Hematol. Oncol., 6, 173-179.
    • (1988) Hematol. Oncol. , vol.6 , pp. 173-179
    • Selby, P.J.1    Zulian, G.2    Forgeson, G.3    Nardi, A.C.4    Milan, S.5    Meldrum, M.6    Viner, C.7    Osborne, R.J.8    Malpas, J.S.9    McElwain, T.J.10
  • 137
    • 78651191735 scopus 로고
    • The disappearance of thymine dimers from DNA: An error-correcting mechanism
    • Setlow, R.B. and W.L. Carrier (1964) The disappearance of thymine dimers from DNA: an error-correcting mechanism, Proc. Natl. Acad. Sci. USA, 51, 226-231.
    • (1964) Proc. Natl. Acad. Sci. USA , vol.51 , pp. 226-231
    • Setlow, R.B.1    Carrier, W.L.2
  • 138
    • 0000696664 scopus 로고
    • Imidazoles, I. Coupling reactions of 5-diazoimidazole-4-carboxamide
    • Shealy, Y.F., C.A. Krauth and J.A. Montgomery (1962) Imidazoles, I. Coupling reactions of 5-diazoimidazole-4-carboxamide, J. Org. Chem., 27, 2150-2154.
    • (1962) J. Org. Chem. , vol.27 , pp. 2150-2154
    • Shealy, Y.F.1    Krauth, C.A.2    Montgomery, J.A.3
  • 141
    • 0015033111 scopus 로고
    • 14C-labeled 7-methylguanine in rats and man after administration of 4(5)-(3,3,-dimethyl-1-triazeno)imidazole 5(4)-carboxamide
    • 14C-labeled 7-methylguanine in rats and man after administration of 4(5)-(3,3,-dimethyl-1-triazeno)imidazole 5(4)-carboxamide, Toxicol. Appl. Pharmacol., 18, 707-719.
    • (1971) Toxicol. Appl. Pharmacol. , vol.18 , pp. 707-719
    • Skibba, J.L.1    Bryan, G.T.2
  • 144
    • 0022457245 scopus 로고
    • Emergence of nitrosourea resistant sublines of Lewis lung tumour following MeCCNU treatment in vivo
    • Stephens, T.C., K. Adams and J.H. Peacock (1986) Emergence of nitrosourea resistant sublines of Lewis lung tumour following MeCCNU treatment in vivo, Br. J. Cancer, 53, 237-245.
    • (1986) Br. J. Cancer , vol.53 , pp. 237-245
    • Stephens, T.C.1    Adams, K.2    Peacock, J.H.3
  • 145
    • 0020075167 scopus 로고
    • The significance of DNA crosslinking to cis-diamminedichloroplatinum(II)-induced cytotoxicity in sensitive and resistant lines of murine leukemia L1210 cells
    • Strandberg, M.C., E. Bresnick and A. Eastman (1982) The significance of DNA crosslinking to cis-diamminedichloroplatinum(II)-induced cytotoxicity in sensitive and resistant lines of murine leukemia L1210 cells, Chem.-Biol. Interactions, 39, 169-180.
    • (1982) Chem.-Biol. Interactions , vol.39 , pp. 169-180
    • Strandberg, M.C.1    Bresnick, E.2    Eastman, A.3
  • 146
    • 0026111317 scopus 로고
    • The 'A rule' of mutagen specificity: A consequence of DNA polymerase bypass of non-instructional lesions?
    • Strauss, B.S. (1991) The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions? BioEssays, 13, 79-84.
    • (1991) BioEssays , vol.13 , pp. 79-84
    • Strauss, B.S.1
  • 147
    • 0026512991 scopus 로고
    • The origin of point mutations in human tumor cells
    • Strauss, B.S. (1992) The origin of point mutations in human tumor cells, Cancer Res., 52, 249-253.
    • (1992) Cancer Res. , vol.52 , pp. 249-253
    • Strauss, B.S.1
  • 149
    • 0018147651 scopus 로고
    • Pharmacokinetics of melphalan following oral or intravenous administration in patients with malignant disease
    • Tattersall, M.H.N., M. Jarman, E.S. Newlands, L. Holyhead, R.A.V. Milstead and A. Weinberg (1978) Pharmacokinetics of melphalan following oral or intravenous administration in patients with malignant disease, Eur. J. Cancer, 14, 507-513.
    • (1978) Eur. J. Cancer , vol.14 , pp. 507-513
    • Tattersall, M.H.N.1    Jarman, M.2    Newlands, E.S.3    Holyhead, L.4    Milstead, R.A.V.5    Weinberg, A.6
  • 150
    • 0024538549 scopus 로고
    • DNA sequence specificity of mitomycin cross-linking
    • Teng, S.P., S.A. Woodson and D.M. Crothers (1989) DNA sequence specificity of mitomycin cross-linking, Biochemistry, 28, 3901-3907.
    • (1989) Biochemistry , vol.28 , pp. 3901-3907
    • Teng, S.P.1    Woodson, S.A.2    Crothers, D.M.3
  • 152
    • 0023142479 scopus 로고
    • Immunological detection of DNA damage caused by melphalan using monoclonal antibodies
    • Tilby, M.J., J.M. Styles and C.J. Dean (1987) Immunological detection of DNA damage caused by melphalan using monoclonal antibodies, Cancer Res., 47, 1542-1546.
    • (1987) Cancer Res. , vol.47 , pp. 1542-1546
    • Tilby, M.J.1    Styles, J.M.2    Dean, C.J.3
  • 153
    • 0025239832 scopus 로고
    • Alkylation of DNA by melphalan in relation to immunoassay of melphalan-DNA adducts: Characterization of monoalkylated and cross-linked products from reaction of melphalan with dGMP and GMP
    • Tilby, M.J., P.D. Lawley and P.B. Farmer (1990) Alkylation of DNA by melphalan in relation to immunoassay of melphalan-DNA adducts: characterization of monoalkylated and cross-linked products from reaction of melphalan with dGMP and GMP, Chem.-Biol. Interactions, 73, 183-194.
    • (1990) Chem.-Biol. Interactions , vol.73 , pp. 183-194
    • Tilby, M.J.1    Lawley, P.D.2    Farmer, P.B.3
  • 154
    • 0027411418 scopus 로고
    • Application of a sensitive immunoassay to the study of DNA adducts formed in peripheral blood mononuclear cells of patients undergoing high-dose melphalan therapy
    • Tilby, M.J., D.R. Newell, C. Viner, P.J. Selby and C.J. Dean (1993) Application of a sensitive immunoassay to the study of DNA adducts formed in peripheral blood mononuclear cells of patients undergoing high-dose melphalan therapy, Eur. J. Cancer, 29A, 681-686.
    • (1993) Eur. J. Cancer , vol.29 A , pp. 681-686
    • Tilby, M.J.1    Newell, D.R.2    Viner, C.3    Selby, P.J.4    Dean, C.J.5
  • 155
    • 0029142953 scopus 로고
    • A monoclonal antibody that recognises alkali-stabilized melphalan-DNA adducts and its application in immunofluorescence microscopy
    • Tilby, M.J., H. McCartney, J. Cordell, A.J. Frank and C.J. Dean (1995) A monoclonal antibody that recognises alkali-stabilized melphalan-DNA adducts and its application in immunofluorescence microscopy, Carcinogenesis, 16, 1895-1901.
    • (1995) Carcinogenesis , vol.16 , pp. 1895-1901
    • Tilby, M.J.1    McCartney, H.2    Cordell, J.3    Frank, A.J.4    Dean, C.J.5
  • 156
    • 0028724559 scopus 로고
    • DNA adducts of the mitomycins
    • K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadlubar, D. Segerback and H. Bartsch (Eds.), IARC Scientific Publication No. 125, IARC, Lyon
    • Tomasz, M. (1994) DNA adducts of the mitomycins, in: K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadlubar, D. Segerback and H. Bartsch (Eds.). DNA Adducts: Identification and Biological Significance, IARC Scientific Publication No. 125, IARC, Lyon, pp. 349-357.
    • (1994) DNA Adducts: Identification and Biological Significance , pp. 349-357
    • Tomasz, M.1
  • 157
    • 0019302936 scopus 로고
    • Crosslinking of DNA by busulfan: Formation of diguaninyl derivatives
    • Tong, W.P. and D.B. Ludlum (1980) Crosslinking of DNA by busulfan: formation of diguaninyl derivatives, Biochim. Biophys. Acta, 608, 174-181.
    • (1980) Biochim. Biophys. Acta , vol.608 , pp. 174-181
    • Tong, W.P.1    Ludlum, D.B.2
  • 158
    • 0020443651 scopus 로고
    • Modifications of DNA by different haloethylnitrosoureas
    • Tong, W.P., K.W. Kohn and D.B. Ludlum (1982) Modifications of DNA by different haloethylnitrosoureas, Cancer Res., 42, 4460-4464.
    • (1982) Cancer Res. , vol.42 , pp. 4460-4464
    • Tong, W.P.1    Kohn, K.W.2    Ludlum, D.B.3
  • 159
    • 0025908492 scopus 로고
    • The isolation of monoclonal antibodies selected for the detection of imidazole ring-opened N7-ethylguanine in purified DNA and in cells in situ. Cross-reactions with methyl, 2-hydroxyethyl and sulphur mustard adducts
    • van Delft, J.H.M., E.J.M. van Weert, MM. Schellekens, E. Claassen and R.A. Baan (1991) The isolation of monoclonal antibodies selected for the detection of imidazole ring-opened N7-ethylguanine in purified DNA and in cells in situ. Cross-reactions with methyl, 2-hydroxyethyl and sulphur mustard adducts, Carcinogenesis, 12, 1041-1049.
    • (1991) Carcinogenesis , vol.12 , pp. 1041-1049
    • Van Delft, J.H.M.1    Van Weert, E.J.M.2    Schellekens, M.M.3    Claassen, E.4    Baan, R.A.5
  • 160
    • 0026777046 scopus 로고
    • Determination of N7-methylguanine in DNA of white blood cells from cancer patients treated with dacarbazine
    • van Delft, J.H.N., A.M.C van der Ende, H.J. Keizer, J. Ouwerkerk and R.A. Baan (1992) Determination of N7-methylguanine in DNA of white blood cells from cancer patients treated with dacarbazine, Carcinogenesis, 13, 1257-1259.
    • (1992) Carcinogenesis , vol.13 , pp. 1257-1259
    • Van Delft, J.H.N.1    Van Der Ende, A.M.C.2    Keizer, H.J.3    Ouwerkerk, J.4    Baan, R.A.5
  • 162
    • 0014409035 scopus 로고
    • s-1 and their removal by the resistant strain
    • s-1 and their removal by the resistant strain, Biochem. Biophys. Res. Commun., 31, 355-360.
    • (1968) Biochem. Biophys. Res. Commun. , vol.31 , pp. 355-360
    • Venitt, S.1
  • 163
    • 0011848419 scopus 로고
    • Carcinogenic and genotoxic effects of antineoplastic agents
    • P.N. Plowman, T.J. McElwain and A.T. Meadows (Eds.), Butterworth-Heinemann, Oxford
    • Venitt, S. (1993) Carcinogenic and genotoxic effects of antineoplastic agents, in: P.N. Plowman, T.J. McElwain and A.T. Meadows (Eds.), Complications of Cancer Management, Butterworth-Heinemann, Oxford, pp. 27-54.
    • (1993) Complications of Cancer Management , pp. 27-54
    • Venitt, S.1
  • 164
    • 0018742066 scopus 로고
    • Concentrative uptake of melphalan, a cancer chemotherapeutic agent which is transported by the leucine-preferring carrier system
    • Vistica, D.T. and M. Rabinovitz (1979) Concentrative uptake of melphalan, a cancer chemotherapeutic agent which is transported by the leucine-preferring carrier system, Biochem. Biophys. Res. Commun., 86, 929-932.
    • (1979) Biochem. Biophys. Res. Commun. , vol.86 , pp. 929-932
    • Vistica, D.T.1    Rabinovitz, M.2
  • 166
    • 0027196091 scopus 로고
    • Constitutive expression of human bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis
    • Walton, M.I., D. Whysong, P.M. O'Connor, D. Hockenbery, S.J. Korsmeyer and K.W. Kohn (1993) Constitutive expression of human bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis, Cancer Res., 53, 1853-1861.
    • (1993) Cancer Res. , vol.53 , pp. 1853-1861
    • Walton, M.I.1    Whysong, D.2    Connor, P.M.3    Hockenbery, D.4    Korsmeyer, S.J.5    Kohn, K.W.6
  • 167
    • 0019166294 scopus 로고
    • Removal of alkyiation products from DNA of E. coli cells treated with the carcinogens N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea: Influence of growth conditions and DNA repair defects
    • Warren, W. and P.D. Lawtey (1980) Removal of alkyiation products from DNA of E. coli cells treated with the carcinogens N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea: influence of growth conditions and DNA repair defects, Carcinogenesis, 1, 67-78.
    • (1980) Carcinogenesis , vol.1 , pp. 67-78
    • Warren, W.1    Lawtey, P.D.2
  • 168
    • 0038497542 scopus 로고
    • Molecular structure of nucleic acids. A structure for deoxyribose nucleic acids
    • Watson, J.D. and F.H.C. Crick (1953a) Molecular structure of nucleic acids. A structure for deoxyribose nucleic acids, Nature (Lond.) 171, 737-738.
    • (1953) Nature (Lond.) , vol.171 , pp. 737-738
    • Watson, J.D.1    Crick, F.H.C.2
  • 169
    • 33749048664 scopus 로고
    • Genetical implications of the structure of deoxyribose nucleic acid
    • Watson, J.D. and F.H.C. Crick (1953b) Genetical implications of the structure of deoxyribose nucleic acid. Nature (Lond.), 171, 964-967.
    • (1953) Nature (Lond.) , vol.171 , pp. 964-967
    • Watson, J.D.1    Crick, F.H.C.2
  • 170
    • 0024786658 scopus 로고
    • Determination at single nucleotide resolution of the sequence specificity of DNA interstrand crosslinking agents in DNA fragments
    • Weidner, M.F., J.T. Millard and P.B. Hopkins (1989) Determination at single nucleotide resolution of the sequence specificity of DNA interstrand crosslinking agents in DNA fragments, J. Am. Chem. Soc., 111, 9270-9272.
    • (1989) J. Am. Chem. Soc. , vol.111 , pp. 9270-9272
    • Weidner, M.F.1    Millard, J.T.2    Hopkins, P.B.3
  • 171
    • 0027054733 scopus 로고
    • Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57B1/6 mice and in human MCL-5 cells
    • White, I.N.H., F. de Matteis, A. Davies, L.L. Smith, C. Crofton-Sleigh, S. Venitt, A. Hewer and D.H. Phillips, Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57B1/6 mice and in human MCL-5 cells, Carcinogenesis, 13, 2197-2203 (1992).
    • (1992) Carcinogenesis , vol.13 , pp. 2197-2203
    • White, I.N.H.1    De Matteis, F.2    Davies, A.3    Smith, L.L.4    Crofton-Sleigh, C.5    Venitt, S.6    Hewer, A.7    Phillips, D.H.8
  • 172
    • 0023252179 scopus 로고
    • Immunological detection and visualization of 8-methoxypsoralen-DNA photoadducts
    • Yang, X.Y., V. DeLeo and R.M. Santella (1987) Immunological detection and visualization of 8-methoxypsoralen-DNA photoadducts, Cancer Res., 47, 2451-2455.
    • (1987) Cancer Res. , vol.47 , pp. 2451-2455
    • Yang, X.Y.1    DeLeo, V.2    Santella, R.M.3
  • 173
    • 0024499111 scopus 로고
    • 8-methoxypsoralen-DNA adducts in patients treated with 8-methoxypsoralen and ultraviolet A light
    • Yang, X.Y., F.P. Gasparro, V.A. DeLeo and R.M. Santella (1989) 8-Methoxypsoralen-DNA adducts in patients treated with 8-methoxypsoralen and ultraviolet A light, J. Invest. Dermatol., 92, 59-63.
    • (1989) J. Invest. Dermatol. , vol.92 , pp. 59-63
    • Yang, X.Y.1    Gasparro, F.P.2    DeLeo, V.A.3    Santella, R.M.4
  • 174
    • 0018771949 scopus 로고
    • DNA-protein and DNA interstrand crosslinking by cis-and transplatinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity
    • Zwelling, L.A., T. Anderson and K.W. Kohn (1979) DNA-protein and DNA interstrand crosslinking by cis-and transplatinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity. Cancer Res., 39, 365-369.
    • (1979) Cancer Res. , vol.39 , pp. 365-369
    • Zwelling, L.A.1    Anderson, T.2    Kohn, K.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.