hMutSβ is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro

Molecular and Cellular Biology

Volumn 22, Issue 7, 2002, Pages 2388-2397

  Zhang, Nianxiang ^a   Lu, Xiaoyan ^a   Zhang, Xiaoshan ^a   Peterson, Carolyn A ^a   Legerski, Randy J ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PSORALEN; UNCOUPLING PROTEIN; CELL CYCLE PROTEIN; CELL EXTRACT; CROSS LINKING REAGENT; CYCLINE; DNA; DNA BINDING PROTEIN; ENDONUCLEASE; ERCC1 PROTEIN, HUMAN; FANCONI ANEMIA PROTEIN; MSH4 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN; PROTEIN SUBUNIT;

ARTICLE; COMPLEX FORMATION; CROSS LINKING; DNA STRAND BREAKAGE; ENZYME SUBSTRATE; EXCISION REPAIR; FANCONI ANEMIA; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; MISMATCH REPAIR; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN PROCESSING; ALKYLATION; BASE MISPAIRING; BIOSYNTHESIS; CELL LINE; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DRUG EFFECT; GEL MOBILITY SHIFT ASSAY; GENETICS; HELA CELL; MACROMOLECULE; METABOLISM;

ALKYLATION; BASE PAIR MISMATCH; CELL CYCLE PROTEINS; CELL EXTRACTS; CELL LINE; CROSS-LINKING REAGENTS; DNA; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDONUCLEASES; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; FICUSIN; HELA CELLS; HUMANS; MACROMOLECULAR SUBSTANCES; NUCLEAR PROTEINS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN SUBUNITS; PROTEINS;

EID: 0036005855     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.7.2388-2397.2002     Document Type: Article

References (66)

1. Mammalian DNA nucleotide excision repair reconstituted with purified protein components
2. DNA replication is required to elicit cellular responses to psoraleninduced DNA interstrand cross-links
3. Nucleotide excision repair genes as determinants of cellular sensitivity to cyclophosphamide analogs
4. N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells
5. Repair of furocoumarin-plus-UVA-induced damage and mutagenic consequences in eukaryotic cells
6. DNA polymerase II (polB) is involved in a new DNA repair pathway for DNA interstrand cross-links in Escherichia coli
7. Evidence for a recombination-independent pathway for the repair of DNA interstrand cross-links based on a site-specific study with nitrogen mustard
8. Physical interaction between components of DNA mismatch repair and nucleotide excision repair
9. Initiation of DNA interstrand cross-link repair in humans: The nucleotide excision repair system makes dual incisions 5′ to the cross-linked base and removes a 22-to 28-nucleotide-long damage-free strand
10. Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism
11. Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines
12. Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage
13. Is Fanconi anaemia caused by a defect in the processing of DNA damage?
14. Mammalian DNA mismatch repair
15. Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes
16. Removal of one nonhomologous DNA end during gene conversion by a RAD1- and MSH2-independent pathway
17. Repair of DNA containing interstrand crosslinks in Escherichia coli: Sequential excision and recombination
18. Removal of psoralen interstrand cross-links from DNA of Escherichia coli: Mechanism and genetic control
19. Induction and removal of DNA interstrand cross-links in V-79 Chinese hamster cells measured by hydroxylapatite chromatography after treatments with bifunctional furocoumarins
20. Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells
21. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
22. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells
23. Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct
24. hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage
25. Sensitivity to DNA cross-linking chemotherapeutic agents in mismatch repair-defective cells in vitro and in xenografts
26. Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex
27. The molecular and cellular biology of Fanconi anemia
28. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
29. Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha
30. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
31. Recombinational and mutagenic repair of psoralen interstrand crosslinks in Saccharomyces cerevisiae
32. ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair
33. Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3
34. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
35. Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents
36. Repair of interstrand cross-links in DNA of Saccharomyces cerevisiae requires two systems for DNA repair: The RAD3 system and the RAD51 system
37. Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination
38. Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair
39. Roles of the DNA mismatch repair and nucleotide excision repair proteins during meiosis
40. Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins
41. Eukaryotic DNA mismatch repair
42. Human endonucleolytic incision of DNA 3′ and 5′ to a site-directed psoralen monoadduct and interstrand cross-link
43. Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease
44. The role of mismatch repair in DNA damage-induced apoptosis
45. Interstrand cross-links induce DNA synthesis in damaged and undamaged plasmids in mammalian cell extracts
46. Requirement for PCNA and RPA in interstrand crosslink-induced DNA synthesis
47. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
48. The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: Comparison of wild-type and repair-deficient strains
49. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract
50. Repair of intermediate structures produced at DNA interstrand cross-links in Saccharomyces corevisiae
51. Genetic control of excision of Saccharomyces cerevisiae interstrand DNA cross-links induced by psoralen plus near-UV light
52. DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts
53. The activity of the DNA-dependent protein kinase (DNA-PK) complex is determinant in the cellular response to nitrogen mustards
54. hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
55. XRCC3 promotes homologgy-directed repair of DNA damage in mammalian cells
56. Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination
57. Positional cloning of a novel fanconi anemia gene, FANCD2
58. Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis
59. Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6
60. The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: Correlation with replicative bypass of platinum-DNA adducts
61. Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair
62. Dissociation of mismatch recognition and ATPase activity by hMSH2-hMSH3
63. Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts
64. Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis
65. Differential processing of UV mimetic and interstrand crosslink damage by XPF cell extracts
66. Expression and physicochemical characterization of human proliferating cell nuclear antigen