메뉴 건너뛰기




Volumn 40, Issue 2, 2004, Pages 122-133

Mutation frequencies in murine keratinocytes as a function of carcinogenic status

Author keywords

Carcinogenesis; Keratinocyte; Malignant progression; Mutagenesis

Indexed keywords

DNA; PSORALEN;

EID: 2942532389     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.20026     Document Type: Article
Times cited : (11)

References (69)
  • 1
    • 0033983935 scopus 로고    scopus 로고
    • Common pathways for ultraviolet skin carcinogenesis in the repair and replication defective groups of xeroderma pigmentosum
    • Cleaver JE. Common pathways for ultraviolet skin carcinogenesis in the repair and replication defective groups of xeroderma pigmentosum. J Dermatol Sci 2000;23:1-11.
    • (2000) J Dermatol Sci , vol.23 , pp. 1-11
    • Cleaver, J.E.1
  • 2
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-1038.
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.3
  • 3
    • 0035495386 scopus 로고    scopus 로고
    • How nucleotide excision repair protects against cancer
    • Friedberg EC. How nucleotide excision repair protects against cancer. Nat Rev Cancer 2001;1:22-33.
    • (2001) Nat Rev Cancer , vol.1 , pp. 22-33
    • Friedberg, E.C.1
  • 4
    • 0036252540 scopus 로고    scopus 로고
    • DNA mismatch repair defects: Role in colorectal carcinogenesis
    • Jacob S, Praz F. DNA mismatch repair defects: Role in colorectal carcinogenesis. Biochimie 2002;84:27-47.
    • (2002) Biochimie , vol.84 , pp. 27-47
    • Jacob, S.1    Praz, F.2
  • 5
    • 0043290038 scopus 로고    scopus 로고
    • DNA repair and tumorigenesis: Lessons from hereditary cancer syndromes
    • Heinen CD, Schmutte C, Fishel R. DNA repair and tumorigenesis: Lessons from hereditary cancer syndromes. Cancer Biol Ther 2002;1:477-485.
    • (2002) Cancer Biol Ther , vol.1 , pp. 477-485
    • Heinen, C.D.1    Schmutte, C.2    Fishel, R.3
  • 6
    • 0141919448 scopus 로고    scopus 로고
    • Genomic instability and cancer
    • Charames GS, Bapat B. Genomic instability and cancer. Curr Mol Med 2003;3:589-596.
    • (2003) Curr Mol Med , vol.3 , pp. 589-596
    • Charames, G.S.1    Bapat, B.2
  • 7
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • Loeb LA. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 1991;51:3075-3079.
    • (1991) Cancer Res , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 8
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC. The clonal evolution of tumor cell populations. Science 1976;194:23-28.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 9
    • 0033011006 scopus 로고    scopus 로고
    • Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog
    • Tomlinson IPM, Bodmer WF. Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog. Nat Med 1999;5:11-12.
    • (1999) Nat Med , vol.5 , pp. 11-12
    • Tomlinson, I.P.M.1    Bodmer, W.F.2
  • 10
    • 0037278519 scopus 로고    scopus 로고
    • Cancer as an evolutionary process at the cell level: An epidemiological perspective
    • Vineis P. Cancer as an evolutionary process at the cell level: An epidemiological perspective. Carcinogenesis 2003;24:1-6.
    • (2003) Carcinogenesis , vol.24 , pp. 1-6
    • Vineis, P.1
  • 11
    • 0036561908 scopus 로고    scopus 로고
    • Modelling the molecular circuitry of cancer
    • Hahn WC, Weinberg RA. Modelling the molecular circuitry of cancer. Nat Rev Cancer 2002;2:331-341.
    • (2002) Nat Rev Cancer , vol.2 , pp. 331-341
    • Hahn, W.C.1    Weinberg, R.A.2
  • 12
    • 0034724312 scopus 로고    scopus 로고
    • Aneuploidy vs. gene mutation hypothesis of cancer: Recent study claims mutation but is found to support aneuploidy
    • Li R, Sonik A, Stindl R, Rasnick D, Duesberg P. Aneuploidy vs. gene mutation hypothesis of cancer: Recent study claims mutation but is found to support aneuploidy. Proc Natl Acad Sci USA 2000;97:3236-3241.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3236-3241
    • Li, R.1    Sonik, A.2    Stindl, R.3    Rasnick, D.4    Duesberg, P.5
  • 13
    • 18344378411 scopus 로고    scopus 로고
    • Prevalence of somatic alterations in the colorectal cancer cell genome
    • Wang T-L, Rago C, Silliman N, et al. Prevalence of somatic alterations in the colorectal cancer cell genome. Proc Natl Acad Sci USA 2002;99:3076-3080.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3076-3080
    • Wang, T.-L.1    Rago, C.2    Silliman, N.3
  • 14
    • 0031893854 scopus 로고    scopus 로고
    • Triplex-directed modification of genes and gene activity
    • Vasquez KM, Wilson JH. Triplex-directed modification of genes and gene activity. Trends Biochem Sci 1998;23:4-9.
    • (1998) Trends Biochem Sci , vol.23 , pp. 4-9
    • Vasquez, K.M.1    Wilson, J.H.2
  • 15
    • 0347812895 scopus 로고    scopus 로고
    • Triplex-forming molecules for modulation of DNA information processing
    • Giovannangeli C, Helene C. Triplex-forming molecules for modulation of DNA information processing. Curr Opin Mol Ther 2000;2:288-296.
    • (2000) Curr Opin Mol Ther , vol.2 , pp. 288-296
    • Giovannangeli, C.1    Helene, C.2
  • 16
    • 0036120314 scopus 로고    scopus 로고
    • Triplex-forming oligonucleotides: Principles and applications
    • Vasquez KM, Glazer PM. Triplex-forming oligonucleotides: Principles and applications. Q Rev Biophys 2002;35:89-107.
    • (2002) Q Rev Biophys , vol.35 , pp. 89-107
    • Vasquez, K.M.1    Glazer, P.M.2
  • 17
    • 0029738829 scopus 로고    scopus 로고
    • High-efficiency triple-helix-mediated photo-cross-linking at a targeted site within a selectable mammalian gene
    • Vasquez KM, Wensel TG, Hogan ME, Wilson JH. High-efficiency triple-helix-mediated photo-cross-linking at a targeted site within a selectable mammalian gene. Biochemistry 1996;35:10712-10719.
    • (1996) Biochemistry , vol.35 , pp. 10712-10719
    • Vasquez, K.M.1    Wensel, T.G.2    Hogan, M.E.3    Wilson, J.H.4
  • 18
    • 0028859271 scopus 로고
    • Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation
    • Wang G, Levy DD, Seidman MM, Glazer PM. Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation. Mol Cell Biol 1995;15:1759-1768.
    • (1995) Mol Cell Biol , vol.15 , pp. 1759-1768
    • Wang, G.1    Levy, D.D.2    Seidman, M.M.3    Glazer, P.M.4
  • 19
    • 0030059301 scopus 로고    scopus 로고
    • Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair
    • Wang G, Seidman MM, Glazer PM. Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair. Science 1996;271:802-805.
    • (1996) Science , vol.271 , pp. 802-805
    • Wang, G.1    Seidman, M.M.2    Glazer, P.M.3
  • 20
    • 0037197844 scopus 로고    scopus 로고
    • Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions
    • Vasquez KM, Christensen J, Li L, Finch RA, Glazer PM. Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions. Proc Natl Acad Sci USA 2002;99:5848-5853.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5848-5853
    • Vasquez, K.M.1    Christensen, J.2    Li, L.3    Finch, R.A.4    Glazer, P.M.5
  • 21
    • 0033766239 scopus 로고    scopus 로고
    • Specific mutations induced by triplex-forming oligonucleotides in mice
    • Vasquez KM, Narayanan L, Glazer PM. Specific mutations induced by triplex-forming oligonucleotides in mice. Science 2000;290:530-533.
    • (2000) Science , vol.290 , pp. 530-533
    • Vasquez, K.M.1    Narayanan, L.2    Glazer, P.M.3
  • 22
    • 0036252564 scopus 로고    scopus 로고
    • Malignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4
    • Mahloogi H, Bassi DE, Klein-Szanto AJP. Malignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4. Carcinogenesis 2002;23:565-572.
    • (2002) Carcinogenesis , vol.23 , pp. 565-572
    • Mahloogi, H.1    Bassi, D.E.2    Klein-Szanto, A.J.P.3
  • 23
    • 0029070961 scopus 로고
    • Human chromosome 11 inhibits tumorigenicity of a murine squamous cell carcinoma cell line
    • Zenklusen JC, Oshimura M, Barrett JC, Conti CJ. Human chromosome 11 inhibits tumorigenicity of a murine squamous cell carcinoma cell line. Genes Chromosomes Cancer 1995;13:47-53.
    • (1995) Genes Chromosomes Cancer , vol.13 , pp. 47-53
    • Zenklusen, J.C.1    Oshimura, M.2    Barrett, J.C.3    Conti, C.J.4
  • 24
    • 0028000722 scopus 로고
    • Inhibition of tumorigenicity of a murine squamous cell carcinoma (SCC) cell line by a putative tumor suppressor gene on human chromosome 7
    • Zenklusen JC, Oshimura M, Barrett JC, Conti CJ. Inhibition of tumorigenicity of a murine squamous cell carcinoma (SCC) cell line by a putative tumor suppressor gene on human chromosome 7. Oncogene 1994;9:2817-2828.
    • (1994) Oncogene , vol.9 , pp. 2817-2828
    • Zenklusen, J.C.1    Oshimura, M.2    Barrett, J.C.3    Conti, C.J.4
  • 25
    • 0024398887 scopus 로고
    • Benzoyl peroxide enhances the invasive ability of a mouse epidermal carcinoma cell line
    • Bonfil RD, Momiki S, Conti CJ, Klein-Szanto AJP. Benzoyl peroxide enhances the invasive ability of a mouse epidermal carcinoma cell line. Int J Cancer 1989;44:165-169.
    • (1989) Int J Cancer , vol.44 , pp. 165-169
    • Bonfil, R.D.1    Momiki, S.2    Conti, C.J.3    Klein-Szanto, A.J.P.4
  • 26
    • 0024529513 scopus 로고
    • Gap-junctional intercellular communication in epidermal cell lines from selected stages of SENCAR mouse skin carcinogenesis
    • Klann RC, Fitzgerald DJ, Piccoli C, Slaga TJ, Yamasaki H. Gap-junctional intercellular communication in epidermal cell lines from selected stages of SENCAR mouse skin carcinogenesis. Cancer Res 1989;49:699-705.
    • (1989) Cancer Res , vol.49 , pp. 699-705
    • Klann, R.C.1    Fitzgerald, D.J.2    Piccoli, C.3    Slaga, T.J.4    Yamasaki, H.5
  • 27
    • 0030815834 scopus 로고    scopus 로고
    • Resistance of transformed mouse keratinocytes to growth inhibition by glucocorticoids
    • Spiegelman VS, Budunova IV, Carbajal S, Slaga TJ. Resistance of transformed mouse keratinocytes to growth inhibition by glucocorticoids. Mol Carcinog 1997;20:99-107.
    • (1997) Mol Carcinog , vol.20 , pp. 99-107
    • Spiegelman, V.S.1    Budunova, I.V.2    Carbajal, S.3    Slaga, T.J.4
  • 28
    • 0023864957 scopus 로고
    • In vivo behavior of murine epidermal cell lines derived from initiated and noninitiated skin
    • Conti CJ, Fries JW, Viaje A, Miller DR, Morris R, Slaga TJ. In vivo behavior of murine epidermal cell lines derived from initiated and noninitiated skin. Cancer Res 1988;48:435-439.
    • (1988) Cancer Res , vol.48 , pp. 435-439
    • Conti, C.J.1    Fries, J.W.2    Viaje, A.3    Miller, D.R.4    Morris, R.5    Slaga, T.J.6
  • 29
    • 0032924478 scopus 로고    scopus 로고
    • Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis
    • La E, Muga SJ, Locniskar MF, Fischer SM. Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis. Mol Carcinog 1999;24:276-286.
    • (1999) Mol Carcinog , vol.24 , pp. 276-286
    • La, E.1    Muga, S.J.2    Locniskar, M.F.3    Fischer, S.M.4
  • 30
    • 0025817256 scopus 로고
    • Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation
    • Beal PA, Dervan PB. Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation. Science 1991;251:1360-1363.
    • (1991) Science , vol.251 , pp. 1360-1363
    • Beal, P.A.1    Dervan, P.B.2
  • 31
    • 0023802737 scopus 로고
    • Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro
    • Cooney M, Czernuszewicz MG, Postel EH, Flint SJ, Hogan ME. Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro. Science 1988;241:456-459.
    • (1988) Science , vol.241 , pp. 456-459
    • Cooney, M.1    Czernuszewicz, M.G.2    Postel, E.H.3    Flint, S.J.4    Hogan, M.E.5
  • 32
    • 0029007162 scopus 로고
    • High-affinity triple helix formation by synthetic oligonucleotides at a site within a selectable mammalian gene
    • Vasquez KM, Wensel TG, Hogan ME, Wilson JH. High-affinity triple helix formation by synthetic oligonucleotides at a site within a selectable mammalian gene. Biochemistry 1995;34:7243-7251.
    • (1995) Biochemistry , vol.34 , pp. 7243-7251
    • Vasquez, K.M.1    Wensel, T.G.2    Hogan, M.E.3    Wilson, J.H.4
  • 33
    • 0026585659 scopus 로고
    • In vivo stability and kinetics of absorption and disposition of 3′ phosphopropyl amine oligonucleotides
    • Zendegui JG, Vasquez KM, Tinsley JH, Kessler DJ, Hogan ME. In vivo stability and kinetics of absorption and disposition of 3′ phosphopropyl amine oligonucleotides. Nucleic Acids Res 1992;20:307-314.
    • (1992) Nucleic Acids Res , vol.20 , pp. 307-314
    • Zendegui, J.G.1    Vasquez, K.M.2    Tinsley, J.H.3    Kessler, D.J.4    Hogan, M.E.5
  • 34
    • 0024988310 scopus 로고
    • Polyomavirus-based shuttle vectors for studying mechanisms of mutagenesis in rodent cells
    • Zernik-Kobak M, Pirsel M, Doniger J, DiPaolo JA, Levine AS, Dixon K. Polyomavirus-based shuttle vectors for studying mechanisms of mutagenesis in rodent cells. Mutat Res 1990;2421:57-65.
    • (1990) Mutat Res , vol.2421 , pp. 57-65
    • Zernik-Kobak, M.1    Pirsel, M.2    Doniger, J.3    DiPaolo, J.A.4    Levine, A.S.5    Dixon, K.6
  • 35
    • 0022399571 scopus 로고
    • A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells
    • Seidman MM, Dixon K, Razzaque A, Zagurski RJ, Berman ML. A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells. Gene 1985;38:233-237.
    • (1985) Gene , vol.38 , pp. 233-237
    • Seidman, M.M.1    Dixon, K.2    Razzaque, A.3    Zagurski, R.J.4    Berman, M.L.5
  • 36
    • 0033557144 scopus 로고    scopus 로고
    • Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells
    • Vasquez KM, Wang G, Havre PA, Glazer PM. Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells. Nucleic Acids Res 1999;27:1176-1181.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1176-1181
    • Vasquez, K.M.1    Wang, G.2    Havre, P.A.3    Glazer, P.M.4
  • 37
    • 0035914386 scopus 로고    scopus 로고
    • Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides
    • Vasquez KM, Dagle JM, Weeks DL, Glazer PM. Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides. J Biol Chem 2001;276:38536-38541.
    • (2001) J Biol Chem , vol.276 , pp. 38536-38541
    • Vasquez, K.M.1    Dagle, J.M.2    Weeks, D.L.3    Glazer, P.M.4
  • 38
    • 0030444452 scopus 로고    scopus 로고
    • Tumor suppressor gene mutations in mice
    • Jacks T. Tumor suppressor gene mutations in mice. Annu Rev Genet 1996;30:603-636.
    • (1996) Annu Rev Genet , vol.30 , pp. 603-636
    • Jacks, T.1
  • 39
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr CJ, McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002;2:103-112.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 40
    • 0036127530 scopus 로고    scopus 로고
    • A role for p53 in the frequency and mechanism of mutation
    • Morris SM. A role for p53 in the frequency and mechanism of mutation. Mutat Res 2002;511:45-62.
    • (2002) Mutat Res , vol.511 , pp. 45-62
    • Morris, S.M.1
  • 41
    • 0033923814 scopus 로고    scopus 로고
    • Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts
    • Andrew SE, Xu XS, Baross-Francis A, et al. Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts. Carcinogenesis 2000;21:1291-1295.
    • (2000) Carcinogenesis , vol.21 , pp. 1291-1295
    • Andrew, S.E.1    Xu, X.S.2    Baross-Francis, A.3
  • 42
    • 0030965212 scopus 로고    scopus 로고
    • Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2
    • Narayanan L, Fritzell JA, Baker SM, Liskay RM, Glazer PM. Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2. Proc Natl Acad Sci USA 1997;94:3122-3127.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3122-3127
    • Narayanan, L.1    Fritzell, J.A.2    Baker, S.M.3    Liskay, R.M.4    Glazer, P.M.5
  • 43
    • 0030817162 scopus 로고    scopus 로고
    • Conditional mutator phenotypes in hMSH2-deficient tumor cell lines
    • Richards B, Zhang H, Phear G, Meuth M. Conditional mutator phenotypes in hMSH2-deficient tumor cell lines. Science 1997;277:1523-1526.
    • (1997) Science , vol.277 , pp. 1523-1526
    • Richards, B.1    Zhang, H.2    Phear, G.3    Meuth, M.4
  • 44
    • 0031419674 scopus 로고    scopus 로고
    • Mutation rate at the hprt locus in human cancer cell lines with specific mismatch repair-gene defects
    • Glaab WE, Tindall KR. Mutation rate at the hprt locus in human cancer cell lines with specific mismatch repair-gene defects. Carcinogenesis 1997;18:1-8.
    • (1997) Carcinogenesis , vol.18 , pp. 1-8
    • Glaab, W.E.1    Tindall, K.R.2
  • 45
    • 0029007870 scopus 로고
    • DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines
    • Branch P, Hampson R, Karran P. DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines. Cancer Res 1995;55:2304-2309.
    • (1995) Cancer Res , vol.55 , pp. 2304-2309
    • Branch, P.1    Hampson, R.2    Karran, P.3
  • 46
    • 0032555201 scopus 로고    scopus 로고
    • Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability
    • Baross-Francis A, Andrew SE, Penney JE, Jirik FR. Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability. Proc Natl Acad Sci USA 1998;95:8739-8743.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8739-8743
    • Baross-Francis, A.1    Andrew, S.E.2    Penney, J.E.3    Jirik, F.R.4
  • 47
    • 0034082063 scopus 로고    scopus 로고
    • Tumors arising in DNA mismatch repair-deficient mice show a wide variation in mutation frequency as assessed by a transgenic reporter gene
    • Baross-Francis A, Milhausen MK, Andrew SE, Jevon G, Jirik FR. Tumors arising in DNA mismatch repair-deficient mice show a wide variation in mutation frequency as assessed by a transgenic reporter gene. Carcinogenesis 2000;21:1259-1262.
    • (2000) Carcinogenesis , vol.21 , pp. 1259-1262
    • Baross-Francis, A.1    Milhausen, M.K.2    Andrew, S.E.3    Jevon, G.4    Jirik, F.R.5
  • 48
    • 0037139195 scopus 로고    scopus 로고
    • Thymic lymphomas arising in Msh2 deficient mice display a large increase in mutation frequency and an altered mutational spectrum
    • Zhang S, Lloyd R, Bowden G, Glickman BW, de Boer J. Thymic lymphomas arising in Msh2 deficient mice display a large increase in mutation frequency and an altered mutational spectrum. Mutat Res 2002;500:67-74.
    • (2002) Mutat Res , vol.500 , pp. 67-74
    • Zhang, S.1    Lloyd, R.2    Bowden, G.3    Glickman, B.W.4    De Boer, J.5
  • 49
    • 0034687650 scopus 로고    scopus 로고
    • Explaining the high mutation rates of cancer cells to drug and multidrug resistance by chromosome reassortments that are catalyzed by aneuploidy
    • Duesberg P, Stindl R, Hehlmann R. Explaining the high mutation rates of cancer cells to drug and multidrug resistance by chromosome reassortments that are catalyzed by aneuploidy. Proc Natl Acad Sci USA 2000;97:14295-14300.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 14295-14300
    • Duesberg, P.1    Stindl, R.2    Hehlmann, R.3
  • 51
    • 0032506125 scopus 로고    scopus 로고
    • Genetic instability in cancer cells is proportional to their degree of aneuploidy
    • Duesberg P, Rausch C, Rasnick D, Hehlmann R. Genetic instability in cancer cells is proportional to their degree of aneuploidy. Proc Natl Acad Sci USA 1998;95:13692-13697.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13692-13697
    • Duesberg, P.1    Rausch, C.2    Rasnick, D.3    Hehlmann, R.4
  • 52
    • 0037406990 scopus 로고    scopus 로고
    • Does the intrinsic instability of aneuploid genomes have a causal role in cancer?
    • Matzke MA, Mette MF, Kanno T, Matzke AJM. Does the intrinsic instability of aneuploid genomes have a causal role in cancer? Trends Genet 2003;19:253-256.
    • (2003) Trends Genet , vol.19 , pp. 253-256
    • Matzke, M.A.1    Mette, M.F.2    Kanno, T.3    Matzke, A.J.M.4
  • 53
    • 0037059043 scopus 로고    scopus 로고
    • The role of chromosomal instability in tumor initiation
    • Nowak MA, Komarova NL, Sengupta A, et al. The role of chromosomal instability in tumor initiation. Proc Natl Acad Sci USA 2002;99:16226-16231.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16226-16231
    • Nowak, M.A.1    Komarova, N.L.2    Sengupta, A.3
  • 56
    • 0030458031 scopus 로고    scopus 로고
    • Increased mutation frequency and altered spectrum in one of four thymic lymphomas derived from tumor prone p53/Big Blue double transgenic mice
    • Buettner VL, Hill KA, Nishino H, Schaid DJ, Frisk CS, Sommer SS. Increased mutation frequency and altered spectrum in one of four thymic lymphomas derived from tumor prone p53/Big Blue double transgenic mice. Oncogene 1996;13:2407-2413.
    • (1996) Oncogene , vol.13 , pp. 2407-2413
    • Buettner, V.L.1    Hill, K.A.2    Nishino, H.3    Schaid, D.J.4    Frisk, C.S.5    Sommer, S.S.6
  • 58
    • 0037173075 scopus 로고    scopus 로고
    • Intestinal adenomas can develop with a stable karyotype and stable microsatellites
    • Haigis KM, Caya JG, Reichelderfer M, Dove WF. Intestinal adenomas can develop with a stable karyotype and stable microsatellites. Proc Natl Acad Sci USA 2002;99:8927-8931.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8927-8931
    • Haigis, K.M.1    Caya, J.G.2    Reichelderfer, M.3    Dove, W.F.4
  • 59
    • 0027452417 scopus 로고
    • Genetic instability occurs in colorectal carcinomas but not it adenomas
    • Young J, Leggett B, Gustafson C, et al. Genetic instability occurs in colorectal carcinomas but not it adenomas. Hum Mutat 1993;2:351-354.
    • (1993) Hum Mutat , vol.2 , pp. 351-354
    • Young, J.1    Leggett, B.2    Gustafson, C.3
  • 61
    • 0023140134 scopus 로고
    • Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: Relevance to malignancy
    • Aldaz CM, Conti CJ, Klein-Szanto AJP, Slaga TJ. Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: Relevance to malignancy. Proc Natl Acad Sci USA 1987;84:2029-2032.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2029-2032
    • Aldaz, C.M.1    Conti, C.J.2    Klein-Szanto, A.J.P.3    Slaga, T.J.4
  • 62
    • 0020586334 scopus 로고
    • Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene
    • Balmain A, Pragnell I. Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene. Nature 1983;303:72-74.
    • (1983) Nature , vol.303 , pp. 72-74
    • Balmain, A.1    Pragnell, I.2
  • 63
    • 0011493380 scopus 로고
    • Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons
    • Bizub D, Wood A, Skalka A. Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons. Proc Natl Acad Sci USA 1986;83:6048-6052.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6048-6052
    • Bizub, D.1    Wood, A.2    Skalka, A.3
  • 64
    • 0022977903 scopus 로고
    • An activated Harvey-ras oncogene produces benign tumors on mouse epidermal tissue
    • Roop DR, Lowy DR, Tambourin PE, et al. An activated Harvey-ras oncogene produces benign tumors on mouse epidermal tissue. Nature 1986;323:822-824.
    • (1986) Nature , vol.323 , pp. 822-824
    • Roop, D.R.1    Lowy, D.R.2    Tambourin, P.E.3
  • 65
    • 0022527161 scopus 로고
    • Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
    • Quintanilla M, Brown K, Ramsden M, Balmain A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 1986;322:78-80.
    • (1986) Nature , vol.322 , pp. 78-80
    • Quintanilla, M.1    Brown, K.2    Ramsden, M.3    Balmain, A.4
  • 66
    • 0025052266 scopus 로고
    • Nonrandom duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors
    • Bianchi AB, Aldaz CM, Conti CJ. Nonrandom duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors. Proc Natl Acad Sci USA 1990;87:6902-6906.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6902-6906
    • Bianchi, A.B.1    Aldaz, C.M.2    Conti, C.J.3
  • 67
    • 0028108985 scopus 로고
    • Database of p53 gene somatic mutations in human tumors and cell lines
    • Hollstein M, Rice K, Greenblatt MS, et al. Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res 1994;22:3551-3555.
    • (1994) Nucleic Acids Res , vol.22 , pp. 3551-3555
    • Hollstein, M.1    Rice, K.2    Greenblatt, M.S.3
  • 68
    • 0026346885 scopus 로고
    • Alterations of the p53 tumor suppressor gene during mouse skin tumor progression
    • Ruggeri B, Caamano J, Goodrow T, et al. Alterations of the p53 tumor suppressor gene during mouse skin tumor progression, Cancer Res 1991;51:6615-6621.
    • (1991) Cancer Res , vol.51 , pp. 6615-6621
    • Ruggeri, B.1    Caamano, J.2    Goodrow, T.3
  • 69
    • 0034235749 scopus 로고    scopus 로고
    • Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cells
    • Ceccotti S, Ciotta C, Fronza G, Dogliotti E, Bignami M. Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cells. Nucleic Acids Res 2000;28:2577-2584.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2577-2584
    • Ceccotti, S.1    Ciotta, C.2    Fronza, G.3    Dogliotti, E.4    Bignami, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.