Chitin research revisited

Marine Drugs

Volumn 8, Issue 7, 2010, Pages 1988-2012

  Khoushab, Feisal ^a   Yamabhai, Montarop ^a  

^a SURANAREE UNIVERSITY OF TECHNOLOGY   (Thailand)

Author keywords

Application; Biotechnology; Chitin; Chito oligosaccharide; Chitosan; Nanobiotechnology; Nanotechnology

Indexed keywords

BIOMATERIAL; CHITIN; CHITIN DERIVATIVE; CHITIN SYNTHASE; CHITINASE; CHITOSAN; CHITOSE OLIGOSACCHARIDE; N ACETYLGLUCOSAMINE; NANOFIBER; POLYURETHAN; POLYVINYL ALCOHOL; UNCLASSIFIED DRUG;

ADSORPTION; ALTERNATIVE ENERGY; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIOXIDANT ACTIVITY; BANDAGES AND DRESSINGS; BIOLOGICAL PEST CONTROL; BIOSYNTHESIS; BIOTECHNOLOGY; CATALYSIS; COMPOSITE MATERIAL; DRUG DELIVERY SYSTEM; ELECTRIC CAPACITANCE; ELECTRIC CONDUCTIVITY; ENCAPSULATION; FOOD PACKAGING; GENETIC ENGINEERING; HEAVY METAL REMOVAL; HEMOSTASIS; HUMAN; HYDROLYSIS; HYPERCHOLESTEROLEMIA; IMMUNOMODULATION; NANOTECHNOLOGY; NERVE REGENERATION; NEUROPROTECTION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OBESITY; PLANT DEFENSE; REVIEW; TISSUE REGENERATION; WOUND HEALING;

EID: 77955288971     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md8071988     Document Type: Review

References (216)

1. Muzzarelli, R.A.A. Chitin; Pergamon Press: Oxford, UK, 1977.
2. Jollès, P.; Muzzarelli, R.A.A. Chitin and Chitinases; Birkhäuser Verlag: Basel, Switzerland, 1999.
3. Jeuniaux, C. A brief survey of the early contribution of European scientists to chitin knowledge. In Advances in Chitin Sciences; Domard, A., Jeuniaux, C., Muzzarelli, R.A.A., Roberts, G., Eds.; Jacques André Publ.: Lyon, France, 1996; pp. 1-9.
4. Muzzarelli, R.A.A.; Muzzarelli, C. Chitin and chitosan hydrogels. In Handbook of Hydrocolloids; Phillips, G.O., Williams, P.A., Eds.; Woodhead Publishing Ltd: Cambridge, UK, 2009; pp. 849-888.
5. Clark, G.L.; Smith, A.F. X-Ray diffraction studies of chitin, chitosan, and derevatives. J. Phys. Chem. 1936, 40, 863-879.
6. Herring, P.J. Marine Ecology and natural products. Pure Appl. Chem. 1979, 51, 1901-1911.
7. Blumenthal, H.J.; Roseman, S. Quantitative estimation of chitin in fungi. J. Bacteriol. 1957, 74, 222-224.
8. Wagner, G.P.; Lo, J.; Laine, R.; Almeder, M. Chitin in the epidermal cuticle of a vertebrate (Paralipophrys trigloides, Blenniidae, Teleostei). Cell. Mol. Life Sci. 1993, 49, 317-319.
9. Struszczyk, M.H. Global requirements for medical applications of chitin and its derivatives. In Polish Chitin Society, Monograph XI; Polish Chitin Society: Lodz, Poland, 2006; pp. 95-102.
10. Mathur, N.K.; Narang, C.K. Chitin and chitosan, versatile polysaccharides from marine animals. J. Chem. Educ. 1990, 67, 938.
11. Sikorski, P.; Hori, R.; Wada, M. Revisit of alpha-chitin crystal structure using high resolution X-ray diffraction data. Biomacromolecules 2009, 10, 1100-1105.
12. Atkins, E. Conformations in polysaccharides and complex carbohydrates. J. Biosci. 1985, 8, 375-387.
13. Lavall, R.L.; Assis, O.B.G.; Campana-Filho, S.P. [beta]-Chitin from the pens of Loligo sp.: Extraction and characterization. Bioresour. Technol. 2007, 98, 2465-2472.
14. Mazeau, K.; Winter, W.T.; Chanzy, H. Molecular and crystal structure of a high-temperature polymorph of chitosan from electron diffraction data. Macromolecules 2002, 27, 7606-7612.
15. Schiffman, J.D.; Schauer, C.L. Solid state characterization of [alpha]-chitin from Vanessa cardui Linnaeus wings. Mater. Sci. Eng. C 2009, 29, 1370-1374.
16. Rudall, K.M.; Kenchington, W. The Chitin System. Biol. Rev. 1973, 48, 597-633.
17. Minke, R.; Blackwell, J. The structure of [alpha]-chitin. J. Mol. Biol. 1978, 120, 167-181.
18. Mano, J.F.; Silva, G.A.; Azevedo, H.S.; Malafaya, P.B.; Sousa, R.A.; Silva, S.S.; Boesel, L.F.; Oliveira, J.M.; Santos, T.C.; Marques, A.P.; Neves, N.M.; Reis, R.L. Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends. J. R. Soc. Interface 2007, 4, 999-1030.
19. Rinaudo, M. Chitin and chitosan: Properties and applications. Prog. Polym. Sci. 2006, 31, 603-632.
20. Bulawa, C.E. Genetics and Molecular Biology of Chitin Synthesis in Fungi. Annu. Rev. Microb. 1993, 47, 505-534. (Pubitemid 23302943)
21. Roncero, C. The genetic complexity of chitin synthesis in fungi. Curr. Genet. 2002, 41, 367-378. (Pubitemid 36075980)
22. Merzendorfer, H. Insect chitin synthases: a review. J. Comp. Physiol. B 2006, 176, 1-15.
23. Kato, N.; Mueller, C.R.; Fuchs, J.F.; Wessely, V.; Lan, Q.; Christensen, B.M. Regulatory mechanisms of chitin biosynthesis and roles of chitin in peritrophic matrix formation in the midgut of adult Aedes aegypti. Insect. Biochem. Mol. Biol. 2006, 36, 1-9.
24. Veronico, P.; Gray, L.J.; Jones, J.T.; Bazzicalupo, P.; Arbucci, S.; Cortese, M.R.; Di Vito, M.; De Giorgi, C. Nematode chitin synthases: gene structure, expression and function in Caenorhabditis elegans and the plant parasitic nematode Meloidogyne artiellia. Mol. Genet. Genomics 2001, 266, 28-34. (Pubitemid 32778659)
25. Cohen, E. Chitin synthesis and inhibition: a revisit. Pest Manag. Sci. 2001, 57, 946-950.
26. McMurrough, I.; Flores-Carreon, A.; Bartnicki-Garcia, S. Pathway of chitin synthesis and cellular localization of chitin synthetase in Mucor rouxii. J. Biol. Chem. 1971, 246, 3999-4007.
27. Kawasaki, T.; Tanaka, M.; Fujie, M.; Usami, S.; Sakai, K.; Yamada, T. Chitin Synthesis in Chlorovirus CVK2-Infected Chlorella Cells. Virology 2002, 302, 123-131. (Pubitemid 35356860)
28. Lerouge, P.; Roche, P.; Faucher, C.; Maillet, F.; Truchet, G.; Prome, J.C.; Denarie, J. Symbiotic host-specificity of Rhizobium meliloti is determined by a sulphated and acylated glucosamine oligosaccharide signal. Nature 1990, 344, 781-784. (Pubitemid 20120611)
29. Semino, C.E.; Robbins, P.W. Synthesis of "Nod"-like chitin oligosaccharides by the Xenopus developmental protein DG42. Proc. Natl. Acad. Sci. USA 1995, 92, 3498-3501.
30. Semino, C.E.; Specht, C.A.; Raimondi, A.; Robbins, P.W. Homologs of the Xenopus developmental gene DG42 are present in zebrafish and mouse and are involved in the synthesis of Nod-like chitin oligosaccharides during early embryogenesis. Proc. Natl. Acad. Sci. USA 1996, 93, 4548-4553.
31. Hawtin, R.E.; Arnold, K.; Ayres, M.D.; Zanotto, P.M.; Howard, S.C.; Gooday, G.W.; Chappell, L.H.; Kitts, P.A.; King, L.A.; Possee, R.D. Identification and preliminary characterization of a chitinase gene in the Autographa californica nuclear polyhedrosis virus genome. Virology 1995, 212, 673-685.
32. Chigaleichik, A.G.; Pirieva, D.A.; Rydkin, S.S. Chitinase from Serratia marcescens BKM B-851. Prikl. Biokhim. Mikrobiol. 1976, 12, 581-586.
33. Kuranda, M.J.; Robbins, P.W. Chitinase is required for cell separation during growth of Saccharomyces cerevisiae. J. Biol. Chem. 1991, 266, 19758-19767. (Pubitemid 21908292)
34. Sakuda, S.; Isogai, A.; Matsumoto, S.; Suzuki, A. Search for microbial insect growth regulators. II. Allosamidin, a novel insect chitinase inhibitor. J. Antibiot. (Tokyo) 1987, 40, 296-300.
35. Kasprzewska, A. Plant chitinases - regulation and function. Cell. Mol. Biol. Lett. 2003, 8, 809-824.
36. Nakazaki, T.; Tsukiyama, T.; Okumoto, Y.; Kageyama, D.; Naito, K.; Inouye, K.; Tanisaka, T. Distribution, structure, organ-specific expression, and phylogenic analysis of the pathogenesis-related protein-3 chitinase gene family in rice (Oryza sativa L.). Genome 2006, 49, 619-630.
37. Bussink, A.P.; Speijer, D.; Aerts, J.M.; Boot, R.G. Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases. Genetics 2007, 177, 959-970.
38. Cohen-Kupiec, R.; Chet, I. The molecular biology of chitin digestion. Curr. Opin. Biotechnol. 1998, 9, 270-277.
39. Coulson, A.F. A proposed structure for 'family 18' chitinases. A possible function for narbonin. FEBS Lett. 1994, 354, 41-44.
40. Itoh, Y.; Kawase, T.; Nikaidou, N.; Fukada, H.; Mitsutomi, M.; Watanabe, T.; Itoh, Y. Functional analysis of the chitin-binding domain of family 19 chitinase from streptomyces griseus HUT6037: substrate-binding affinity and cis-dominant increase of antifungal function. Biosci. Biotechnol. Biochem. 2002, 66, 1084-1092. (Pubitemid 39251305)
41. Funkhouser, J.D.; Aronson, N.N., Jr. Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family. BMC Evol. Biol. 2007, 7, 96.
42. Sendai, Y.; Abe, H.; Kikuchi, M.; Satoh, T.; Hoshi, H. Purification and molecular cloning of bovine oviduct-specific glycoprotein. Biol. Reprod. 1994, 50, 927-934. (Pubitemid 24085234)
43. Hu, B.; Trinh, K.; Figueira, W.F.; Price, P.A. Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family. J. Biol. Chem. 1996, 271, 19415-19420.
44. Hakala, B.E.; White, C.; Recklies, A.D. Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family. J. Biol. Chem. 1993, 268, 25803-25810.
45. Johansen, J.S.; Olee, T.; Price, P.A.; Hashimoto, S.; Ochs, R.L.; Lotz, M. Regulation of YKL-40 production by human articular chondrocytes. Arthritis Rheum. 2001, 44, 826-837. (Pubitemid 32319775)
46. Kirkpatrick, R.B.; Emery, J.G.; Connor, J.R.; Dodds, R.; Lysko, P.G.; Rosenberg, M. Induction and Expression of Human Cartilage Glycoprotein 39 in Rheumatoid Inflammatory and Peripheral Blood Monocyte-Derived Macrophages. Exp. Cell Res. 1997, 237, 46-54.
47. Chang, N.-C.A.; Hung, S.-I.; Hwa, K.-Y.; Kato, I.; Chen, J.-E.; Liu, C.-H.; Chang, A.C. A Macrophage Protein, Ym1, Transiently Expressed during Inflammation Is a Novel Mammalian Lectin. J. Biol. Chem. 2001, 276, 17497-17506.
48. Webb, D.C.; McKenzie, A.N.J.; Foster, P.S. Expression of the Ym2 Lectin-binding Protein Is Dependent on Interleukin (IL)-4 and IL-13 Signal Transduction. J. Biol. Chem. 2001, 276, 41969-41976.
49. Owhashi, M.; Arita, H.; Hayai, N. Identification of a Novel Eosinophil Chemotactic Cytokine (ECF-L) as a Chitinase Family Protein. J. Biol. Chem. 2000, 275, 1279-1286. (Pubitemid 30051182)
50. Lee, C.G.; Hartl, D.; Lee, G.R.; Koller, B.; Matsuura, H.; Da Silva, C.A.; Sohn, M.H.; Cohn, L.; Homer, R.J.; Kozhich, A.A.; Humbles, A.; Kearley, J.; Coyle, A.; Chupp, G.; Reed, J.; Flavell, R.A.; Elias, J.A. Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J. Exp. Med. 2009, 206, 1149-1166.
51. Shackelton, L.M.; Mann, D.M.; Millis, A.J.T. Identification of a 38-kDa Heparin-binding Glycoprotein (gp38k) in Differentiating Vascular Smooth Muscle Cells as a Member of a Group of Proteins Associated with Tissue Remodeling. J. Biol. Chem. 1995, 270, 13076-13083.
52. Verhage, H.G.; Mavrogianis, P.A.; O'Day-Bowman, M.B.; Schmidt, A.; Arias, E.B.; Donnelly, K.M.; Boomsma, R.A.; Thibodeaux, J.K.; Fazleabas, A.T.; Jaffe, R.C. Characteristics of an oviductal glycoprotein and its potential role in the fertilization process. Biol. Reprod. 1998, 58, 1098-1101. (Pubitemid 28217229)
53. Johansen, J.S. Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer. Dan. Med. Bull. 2006, 53, 172-209.
54. Renkema, G.H.; Boot, R.G.; Muijsers, A.O.; Donker-Koopman, W.E.; Aerts, J.M.F.G. Purification and Characterization of Human Chitotriosidase, a Novel Member of the Chitinase Family of Proteins. J. Biol. Chem. 1995, 270, 2198-2202.
55. Boot, R.G.; Blommaart, E.F.C.; Swart, E.; Ghauharali-van der Vlugt, K.; Bijl, N.; Moe, C.; Place, A.; Aerts, J.M.F.G. Identification of a Novel Acidic Mammalian Chitinase Distinct from Chitotriosidase. J. Biol. Chem. 2001, 276, 6770-6778. (Pubitemid 37373543)
56. Boot, R.G.; Renkema, G.H.; Strijland, A.; van Zonneveld, A.J.; Aerts, J.M. Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages. J. Biol. Chem. 1995, 270, 26252-26256.
57. Krykbaev, R.; Fitz, L.J.; Reddy, P.S.; Winkler, A.; Xuan, D.; Yang, X.; Fleming, M.; Wolf, S.F. Evolutionary and biochemical differences between human and monkey acidic mammalian chitinases. Gene 2010, 452, 63-71.
58. Kzhyshkowska, J.; Gratchev, A.; Goerdt, S. Human chitinases and chitinase-like proteins as indicators for inflammation and cancer. Biomark Insights 2007, 2, 128-146.
59. Kolstad, G.; Synstad, B.; Eijsink, V.G.; van Aalten, D.M. Structure of the D140N mutant of chitinase B from Serratia marcescens at 1.45 A resolution. Acta Crystallogr. D Biol. Crystallogr. 2002, 58, 377-379. (Pubitemid 34179228)
60. Vaaje-Kolstad, G.; Houston, D.R.; Rao, F.V.; Peter, M.G.; Synstad, B.; van Aalten, D.M.; Eijsink, V.G. Structure of the D142N mutant of the family 18 chitinase ChiB from Serratia marcescens and its complex with allosamidin. Biochim. Biophys. Acta 2004, 1696, 103-111.
61. van Aalten, D.M.; Synstad, B.; Brurberg, M.B.; Hough, E.; Riise, B.W.; Eijsink, V.G.; Wierenga, R.K. Structure of a two-domain chitotriosidase from Serratia marcescens at 1.9-A resolution. Proc. Natl. Acad. Sci. USA 2000, 97, 5842-5847.
62. Ferrandon, S.; Sterzenbach, T.; Mersha, F.B.; Xu, M.Q. A single surface tryptophan in the chitin-binding domain from Bacillus circulans chitinase A1 plays a pivotal role in binding chitin and can be modified to create an elutable affinity tag. Biochim. Biophys. Acta 2003, 1621, 31-40.
63. Hardt, M.; Laine, R.A. Mutation of active site residues in the chitin-binding domain ChBDChiA1 from chitinase A1 of Bacillus circulans alters substrate specificity: use of a green fluorescent protein binding assay. Arch Biochem. Biophys. 2004, 426, 286-297.
64. Jee, J.G.; Ikegami, T.; Hashimoto, M.; Kawabata, T.; Ikeguchi, M.; Watanabe, T.; Shirakawa, M. Solution structure of the fibronectin type III domain from Bacillus circulans WL-12 chitinase A1. J. Biol. Chem. 2002, 277, 1388-1397. (Pubitemid 34968895)
65. Watanabe, T.; Uchida, M.; Kobori, K.; Tanaka, H. Site-directed mutagenesis of the Asp-197 and Asp-202 residues in chitinase A1 of Bacillus circulans WL-12. Biosci. Biotechnol. Biochem. 1994, 58, 2283-2285.
66. Watanabe, T.; Ariga, Y.; Sato, U.; Toratani, T.; Hashimoto, M.; Nikaidou, N.; Kezuka, Y.; Nonaka, T.; Sugiyama, J. Aromatic residues within the substrate-binding cleft of Bacillus circulans chitinase A1 are essential for hydrolysis of crystalline chitin. Biochem. J. 2003, 376, 237-244. (Pubitemid 37487219)
67. Watanabe, T.; Kobori, K.; Miyashita, K.; Fujii, T.; Sakai, H.; Uchida, M.; Tanaka, H. Identification of glutamic acid 204 and aspartic acid 200 in chitinase A1 of Bacillus circulans WL-12 as essential residues for chitinase activity. J. Biol. Chem. 1993, 268, 18567-18572. (Pubitemid 23273791)
68. Songsiriritthigul, C.; Pantoom, S.; Aguda, A.H.; Robinson, R.C.; Suginta, W. Crystal structures of Vibrio harveyi chitinase A complexed with chitooligosaccharides: implications for the catalytic mechanism. J. Struct. Biol. 2008, 162, 491-499.
69. Suginta, W.; Songsiriritthigul, C.; Kobdaj, A.; Opassiri, R.; Svasti, J. Mutations of Trp275 and Trp397 altered the binding selectivity of Vibrio carchariae chitinase A. Biochim. Biophys. Acta 2007, 1770, 1151-1160. (Pubitemid 47002140)
70. Suginta, W.; Vongsuwan, A.; Songsiriritthigul, C.; Svasti, J.; Prinz, H. Enzymatic properties of wild-type and active site mutants of chitinase A from Vibrio carchariae, as revealed by HPLC-MS. FEBS J. 2005, 272, 3376-3386. (Pubitemid 40979308)
71. Karasuda, S.; Tanaka, S.; Kajihara, H.; Yamamoto, Y.; Koga, D. Plant chitinase as a possible biocontrol agent for use instead of chemical fungicides. Biosci. Biotechnol. Biochem. 2003, 67, 221-224. (Pubitemid 39260174)
72. Mostafa, S.A.; Mahmoud, M.S.; Mohamed, Z.K.; Enan, M.R. Cloning and molecular characterization of chitinase from Bacillus licheniformis MS-3. J. Gen. Appl. Microbiol. 2009, 55, 241-246.
73. Tsujibo, H.; Kubota, T.; Yamamoto, M.; Miyamoto, K.; Inamori, Y. Characterization of chitinase genes from an alkaliphilic actinomycete, Nocardiopsis prasina OPC-131. Appl. Environ. Microbiol. 2003, 69, 894-900. (Pubitemid 36204816)
74. Bhattacharya, D.; Nagpure, A.; Gupta, R.K. Bacterial chitinases: properties and potential. Crit. Rev. Biotechnol. 2007, 27, 21-28.
75. Dahiya, N.; Tewari, R.; Hoondal, G.S. Biotechnological aspects of chitinolytic enzymes: a review. Appl. Microbiol. Biotechnol. 2006, 71, 773-782.
76. Hayes, M.; Carney, B.; Slater, J.; Bruck, W. Mining marine shellfish wastes for bioactive molecules: chitin and chitosan - Part B: applications. Biotechnol. J. 2008, 3, 878-889.
77. Songsiriritthigul, C.; Pesatcha, P.; Eijsink, V.G.; Yamabhai, M. Directed evolution of a Bacillus chitinase. Biotechnol. J. 2009, 4, 501-509.
78. Howard, M.B.; Ekborg, N.A.; Weiner, R.M.; Hutcheson, S.W. Detection and characterization of chitinases and other chitin-modifying enzymes. J. Ind. Microbiol. Biotechnol. 2003, 30, 627-635.
79. Patil, R.S.; Ghormade, V.V.; Deshpande, M.V. Chitinolytic enzymes: an exploration. Enzyme Microb. Technol. 2000, 26, 473-483.
80. Songsiriritthigul, C.; Lapboonrueng, S.; Pechsrichuang, P.; Pesatcha, P.; Yamabhai, M. Expression and characterization of Bacillus licheniformis chitinase (ChiA), suitable for bioconversion of chitin waste. Bioresour. Technol. 2010, 101, 4096-4103.
81. Kawabata, S.; Nagayama, R.; Hirata, M.; Shigenaga, T.; Agarwala, K.L.; Saito, T.; Cho, J.; Nakajima, H.; Takagi, T.; Iwanaga, S. Tachycitin, a small granular component in horseshoe crab hemocytes, is an antimicrobial protein with chitin-binding activity. J. Biochem. 1996, 120, 1253-1260.
82. Van Dellen, K.L.; Chatterjee, A.; Ratner, D.M.; Magnelli, P.E.; Cipollo, J.F.; Steffen, M.; Robbins, P.W.; Samuelson, J. Unique posttranslational modifications of chitin-binding lectins of Entamoeba invadens cyst walls. Eukaryot. Cell 2006, 5, 836-848. (Pubitemid 43794482)
83. Broekaert, W.F.; Van Parijs, J.; Leyns, F.; Joos, H.; Peumans, W.J. A Chitin-Binding Lectin from Stinging Nettle Rhizomes with Antifungal Properties. Science 1989, 245, 1100-1102.
84. Willis, J.H. Structural cuticular proteins from arthropods: annotation, nomenclature, and sequence characteristics in the genomics era. Insect. Biochem. Mol. Biol. 2010, 40, 189-204.
85. Tang, L.; Liang, J.; Zhan, Z.; Xiang, Z.; He, N. Identification of the chitin-binding proteins from the larval proteins of silkworm, Bombyx mori. Insect. Biochem. Mol. Biol. 2010, 40, 228-234.
86. Jasrapuria, S.; Arakane, Y.; Osman, G.; Kramer, K.J.; Beeman, R.W.; Muthukrishnan, S. Genes encoding proteins with peritrophin A-type chitin-binding domains in Tribolium castaneum are grouped into three distinct families based on phylogeny, expression and function. Insect. Biochem. Mol. Biol. 2010, 40, 214-227.
87. Selitrennikoff, C.P. Antifungal Proteins. Appl. Environ. Microbiol. 2001, 67, 2883-2894.
88. Asensio, J.L.; Canada, F.J.; Siebert, H.C.; Laynez, J.; Poveda, A.; Nieto, P.M.; Soedjanaamadja, U.M.; Gabius, H.J.; Jimenez-Barbero, J. Structural basis for chitin recognition by defense proteins: GlcNAc residues are bound in a multivalent fashion by extended binding sites in hevein domains. Chem. Biol. 2000, 7, 529-543. (Pubitemid 30466987)
89. Bormann, C.; Baier, D.; Horr, I.; Raps, C.; Berger, J.; Jung, G.; Schwarz, H. Characterization of a novel, antifungal, chitin-binding protein from Streptomyces tendae Tu901 that interferes with growth polarity. J. Bacteriol. 1999, 181, 7421-7429.
90. Chae, K.S.; Lee, I.H.; Choi, C.S.; Kim, H.R. Purification and characterization of chitin-binding proteins from the hemolymph of sweet potato hornworm, Agrius convolvuli. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 1999, 124, 475-481.
91. De Bolle, M.F.; David, K.M.; Rees, S.B.; Vanderleyden, J.; Cammue, B.P.; Broekaert, W.F. Cloning and characterization of a cDNA encoding an antimicrobial chitin-binding protein from amaranth, Amaranthus caudatus. Plant Mol. Biol. 1993, 22, 1187-1190.
92. Huang, X.; Xie, W.; Gong, Z. Characteristics and antifungal activity of a chitin binding protein from Ginkgo biloba. FEBS Lett. 2000, 478, 123-126.
93. Kolbe, S.; Fischer, S.; Becirevic, A.; Hinz, P.; Schrempf, H. The Streptomyces reticuli alphachitin- binding protein CHB2 and its gene. Microbiology 1998, 144 (Pt 5), 1291-1297.
94. Hamodrakas, S.J.; Willis, J.H.; Iconomidou, V.A. A structural model of the chitin-binding domain of cuticle proteins. Insect. Biochem. Mol. Biol. 2002, 32, 1577-1583.
95. Willis, J.H. Cuticular Proteins in Insects and Crustaceans. Am. Zool. 1999, 39, 600-609.
96. Eijsink, V.G.; Vaaje-Kolstad, G.; Varum, K.M.; Horn, S.J. Towards new enzymes for biofuels: lessons from chitinase research. Trends Biotechnol. 2008, 26, 228-235.
97. Vaaje-Kolstad, G.; Horn, S.J.; van Aalten, D.M.; Synstad, B.; Eijsink, V.G. The non-catalytic chitin-binding protein CBP21 from Serratia marcescens is essential for chitin degradation. J. Biol. Chem. 2005, 280, 28492-28497. (Pubitemid 41105749)
98. Endo, T.; Koizumi, S. Large-scale production of oligosaccharides using engineered bacteria. Curr. Opin. Struct. Biol. 2000, 10, 536-541.
99. Cottaz, S.; Samain, E. Genetic engineering of Escherichia coli for the production of NI,NII-diacetylchitobiose (chitinbiose) and its utilization as a primer for the synthesis of complex carbohydrates. Metab. Eng. 2005, 7, 311-317. (Pubitemid 41225448)
100. Samain, E.; Drouillard, S.; Heyraud, A.; Driguez, H.; Geremia, R.A. Gram-scale synthesis of recombinant chitooligosaccharides in Escherichia coli. Carbohydr. Res. 1997, 302, 35-42. (Pubitemid 27343475)
101. Samain, E.; Chazalet, V.; Geremia, R.A. Production of O-acetylated and sulfated chitooligosaccharides by recombinant Escherichia coli strains harboring different combinations of nod genes. J. Biotechnol. 1999, 72, 33-47.
102. van der Holst, P.P.; Schlaman, H.R.; Spaink, H.P. Proteins involved in the production and perception of oligosaccharides in relation to plant and animal development. Curr. Opin. Struct. Biol. 2001, 11, 608-616.
103. Amatayakul-Chantler, S.; Ferguson, M.A.J.; Dwek, R.A.; Rademacher, T.W.; Parekh, R.B.; Crandall, I.E.; Newell, P.C. Cell surface oligosaccharides on Dictyostelium during development. J. Cell Sci. 1975, 99, 485-495.
104. Varki, A.; Marth, J. Oligosaccharides in vertebrate development. Semin. Dev. Biol. 1995, 6, 127-138.
105. Bakkers, J.; Semino, C.E.; Stroband, H.; Kijne, J.W.; Robbins, P.W.; Spaink, H.P. An important developmental role for oligosaccharides during early embryogenesis of cyprinid fish. Proc. Natl. Acad. Sci. USA 1997, 94, 7982-7986.
106. Iglesias, M.; Soler, R.M.; Ribera, J.; Esquerda, J.E.; Comella, J.X. The carbohydrate N-acetylglucosamine is involved in the guidance of neurites from chick ciliary ganglion neurons through the extracellular matrix of rat skeletal muscle fiber. Neurosci. Lett. 1996, 207, 81-84.
107. Wells, L.; Whelan, S.A.; Hart, G.W. O-GlcNAc: a regulatory post-translational modification. Biochem. Biophys. Res. Commun. 2003, 302, 435-441.
108. Hurtado-Guerrero, R.; Dorfmueller, H.C.; van Aalten, D.M. Molecular mechanisms of O-GlcNAcylation. Curr. Opin. Struct. Biol. 2008, 18, 551-557.
109. Hart, G.W. Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins. Annu. Rev. Biochem. 1997, 66, 315-335. (Pubitemid 27274659)
110. Kang, E.-S.; Han, D.; Park, J.; Kwak, T.K.; Oh, M.-A.; Lee, S.-A.; Choi, S.; Park, Z.Y.; Kim, Y.; Lee, J.W. O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic [beta] cells. Exp. Cell Res. 2008, 314, 2238-2248.
111. Yanagisawa, M.; Yu, R.K. O-linked beta-N-acetylglucosaminylation in mouse embryonic neural precursor cells. J. Neurosci. Res. 2009, 87, 3535-3545.
112. Lazarus, B.D.; Love, D.C.; Hanover, J.A. O-GlcNAc cycling: Implications for neurodegenerative disorders. Int. J. Biochem. Cell Biol. 2009, 41, 2134-2146.
113. Zeidan, Q.; Hart, G.W. The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways. J. Cell Sci. 2010, 123, 13-22.
114. Zachara, N.E.; Hart, G.W. Cell signaling, the essential role of O-GlcNAc! Biochim. Biophys. Acta 2006, 1761, 599-617.
115. Tallent, M.K.; Varghis, N.; Skorobogatko, Y.; Hernandez-Cuebas, L.; Whelan, K.; Vocadlo, D.J.; Vosseller, K. In Vivo Modulation of O-GlcNAc Levels Regulates Hippocampal Synaptic Plasticity through Interplay with Phosphorylation. J. Biol. Chem. 2009, 284, 174-181.
116. Brimble, S.; Wollaston-Hayden, E.E.; Teo, C.F.; Morris, A.C.; Wells, L. The Role of the O-GlcNAc Modification in Regulating Eukaryotic Gene Expression. Curr. Signal Transd. Ther. 2010, 5, 12-24.
117. Comer, F.I.; Hart, G.W. O-GlcNAc and the control of gene expression. Biochim. Biophys. Acta 1999, 1473, 161-171.
118. Hart, G.W.; Housley, M.P.; Slawson, C. Cycling of O-linked [beta]-N-acetylglucosamine on nucleocytoplasmic proteins. Nature 2007, 446, 1017-1022. (Pubitemid 46676063)
119. Zachara, N.E.; Hart, G.W. O-GlcNAc modification: a nutritional sensor that modulates proteasome function. Trends Cell Biol. 2004, 14, 218-221.
120. Kang, J.G.; Park, S.Y.; Ji, S.; Jang, I.; Park, S.; Kim, H.S.; Kim, S.M.; Yook, J.I.; Park, Y.I.; Roth, J.; Cho, J.W. O-GlcNAc protein modification in cancer cells increases in response to glucose deprivation through glycogen degradation. J. Biol. Chem. 2009, 284, 34777-34784.
121. Whelan, S.A.; Dias, W.B.; Thiruneelakantapillai, L.; Lane, M.D.; Hart, G.W. Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes. J. Biol. Chem. 2010, 285, 5204-5211.
122. Duverger, E.; Roche, A.-C.; Monsigny, M. N-Acetylglucosamine-dependent nuclear import of neoglycoproteins. Glycobiology 1996, 6, 381-386.
123. Guinez, C.; Morelle, W.; Michalski, J.-C.; Lefebvre, T. O-GlcNAc glycosylation: a signal for the nuclear transport of cytosolic proteins? Int. J. Biochem. Cell Biol. 2005, 37, 765-774. (Pubitemid 40202998)
124. Chatham, J.C.; Marchase, R.B. Protein O-GlcNAcylation: A Critical Regulator of the Cellular Response to Stress. Curr. Signal Transduction Ther. 2010, 5, 49-59.
125. Pappa, A.; Guerini, D. Immune Regulation by the Posttranslational Modification O-GlcNAc. Curr. Signal Transduction Ther. 2010, 5, 41-48.
126. Aam, B.B.; Heggset, E.B.; Norberg, A.L.; Sørlie, M.; Vårum, K.M.; Eijsink, V.G.H. Production of Chitooligosaccharides and Their Potential Applications in Medicine. Mar. Drugs 2010, 8, 1482-1517.
127. Muzzarelli, R.A.A. Chitins and chitosans as immunoadjuvants and non-allergenic drug carriers. Mar. Drugs 2010, 8, 292-312.
128. Jeong, H.J.; Koo, H.N.; Oh, E.Y.; Chae, H.J.; Kim, H.R.; Suh, S.B.; Kim, C.H.; Cho, K.H.; Park, B.R.; Park, S.T.; Lee, Y.M.; Kim, H.M. Nitric oxide production by high molecular weight water-soluble chitosan via nuclear factor-kappaB activation. Int. J. Immunopharmacol. 2000, 22, 923-933.
129. Minami, S.; Suzuki, H.; Okamoto, Y.; Fujinaga, T.; Shigemasa, Y. Chitin and chitosan activate complement via the alternative pathway. Carbohydr. Polym. 1998, 36, 151-155. (Pubitemid 128399588)
130. Freier, T.; Montenegro, R.; Shan Koh, H.; Shoichet, M.S. Chitin-based tubes for tissue engineering in the nervous system. Biomaterials 2005, 26, 4624-4632. (Pubitemid 40269279)
131. Klokkevold, P.R.; Fukayama, H.; Sung, E.C.; Bertolami, C.N. The effect of chitosan (poly-N-acetyl glucosamine) on lingual hemostasis in heparinized rabbits. J. Oral Maxillofac. Surg. 1999, 57, 49-52.
132. Okamoto, Y.; Yano, R.; Miyatake, K.; Tomohiro, I.; Shigemasa, Y.; Minami, S. Effects of chitin and chitosan on blood coagulation. Carbohydr. Polym. 2003, 53, 337-342.
133. Shelma, R; Paul, W.; Sharma, C.P. Chitin Nanofibre Reinforced Thin Chitosan Films for Wound Healing Application. Trends Biomater. Artif. Organs 2008, 22, 111-115.
134. Mi, F.-L.; Shyu, S.-S.; Wu, Y.-B.; Lee, S.-T.; Shyong, J.-Y.; Huang, R.-N. Fabrication and characterization of a sponge-like asymmetric chitosan membrane as a wound dressing. Biomaterials 2001, 22, 165-173.
135. Ong, S.-Y.; Wu, J.; Moochhala, S.M.; Tan, M.-H.; Lu, J. Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties. Biomaterials 2008, 29, 4323-4332.
136. Dai, T.; Tegos, G.P.; Burkatovskaya, M.; Castano, A.P.; Hamblin, M.R. Chitosan acetate bandage as a topical antimicrobial dressing for infected burns. Antimicrob. Agents Chemother. 2009, 53, 393-400.
137. Brandl, F.; Sommer, F.; Goepferich, A. Rational design of hydrogels for tissue engineering: Impact of physical factors on cell behavior. Biomaterials 2007, 28, 134-146. (Pubitemid 44537395)
138. Tsioptsias, C.; Tsivintzelis, I.; Papadopoulou, L.; Panayiotou, C. A novel method for producing tissue engineering scaffolds from chitin, chitin-hydroxyapatite, and cellulose. Mater. Sci. Eng. C 2009, 29, 159-164.
139. Drury, J.L.; Mooney, D.J. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 2003, 24, 4337-4351. (Pubitemid 36960132)
140. Khor, E.; Lim, L.Y. Implantable applications of chitin and chitosan. Biomaterials 2003, 24, 2339-2349.
141. Gong, Y.; Gong, L.; Gu, X.; Ding, F. Chitooligosaccharides promote peripheral nerve regeneration in a rabbit common peroneal nerve crush injury model. Microsurgery 2009, 29, 650-656.
142. Razdan, A.; Pettersson, D. Effect of chitin and chitosan on nutrient digestibility and plasma lipid concentrations in broiler chickens. Br. J. Nutr. 1994, 72, 277-288. (Pubitemid 24255088)
143. Muzzarelli, R.A.A.; Muzzarelli, C. Chitosan, a dietary supplement and a food technology commodity. In Functional Food Carbohydrates; Biliaderis, C.G., Izydorczyk, M.S., Eds.; Francis and Taylor: Orlando, FL, USA, 2006; pp. 215-248.
144. Gallaher, C.M.; Munion, J.; Hesslink, R., Jr.; Wise, J.; Gallaher, D.D. Cholesterol Reduction by Glucomannan and Chitosan Is Mediated by Changes in Cholesterol Absorption and Bile Acid and Fat Excretion in Rats. J. Nutr. 2000, 130, 2753-2759.
145. Burton-Freeman, B. Dietary Fiber and Energy Regulation. J. Nutr. 2000, 130, 272-275.
146. Maezaki, Y.; Tsuji, K.; Nakagawa, Y.; Kawai, Y.; Akimoto, M.; Tsugita, T.; Takekawa, W.; Terada, A.; Hara, H.; Mitsuoka, T. Hypocholesterolemic Effect of Chitosan in Adult Males. Biosci. Biotech. Biochem. 1993, 57, 1439-1444.
147. Dev, A.; Mohan, J.C.; Sreeja, V.; Tamura, H.; Patzke, G.R.; Hussain, F.; Weyeneth, S.; Nair, S.V.; Jayakumar, R. Novel carboxymethyl chitin nanoparticles for cancer drug delivery applications. Carbohydr. Polym. 2010, 79, 1073-1079.
148. Kamiyama, K.; Onishi, H.; Machida, Y. Biodisposition characteristics of N-succinyl-chitosan and glycol- chitosan in normal and tumor-bearing mice. Biol. Pharm. Bull. 1999, 22, 179-186. (Pubitemid 29114036)
149. Ishihara, M.; Obara, K.; Nakamura, S.; Fujita, M.; Masuoka, K.; Kanatani, Y.; Takase, B.; Hattori, H.; Morimoto, Y.; Ishihara, M.; Maehara, T.; Kikuchi, M. Chitosan hydrogel as a drug delivery carrier to control angiogenesis. J. Artif. Organs 2006, 9, 8-16.
150. Zhao, Y.; Chen, G.; Sun, M.; Jin, Z.; Gao, C. Study on preparation of the pH sensitive hydroxyethyl chitin/poly (acrylic acid) hydrogel and its drug release property. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2006, 23, 338-341.
151. Janes, K.A.; Calvo, P.; Alonso, M.J. Polysaccharide colloidal particles as delivery systems for macromolecules. Adv. Drug Deliv. Rev. 2001, 47, 83-97. (Pubitemid 32209234)
152. Haidar, Z.S.; Hamdy, R.C.; Tabrizian, M. Protein release kinetics for core-shell hybrid nanoparticles based on the layer-by-layer assembly of alginate and chitosan on liposomes. Biomaterials 2008, 29, 1207-1215.
153. Calvo, P.; Remuñán-López, C.; Vila-Jato, J.L.; Alonso, M.J. Novel hydrophilic chitosanpolyethylene oxide nanoparticles as protein carriers. J. Appl. Polym. Sci. 1997, 63, 125-132. (Pubitemid 127613982)
154. Bodmeier, R.; Chen, H.; Paeratakul, O. A Novel Approach to the Oral Delivery of Micro- or Nanoparticles. Pharm. Res. 1989, 6, 413-417. (Pubitemid 19176086)
155. Calabrese, V.; Lodi, R.; Tonon, C.; D'Agata, V.; Sapienza, M.; Scapagnini, G.; Mangiameli, A.; Pennisi, G.; Stella, A.M.G.; Butterfield, D.A. Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia. J. Neurol. Sci. 2005, 233, 145-162. (Pubitemid 40812334)
156. Ngo, D.-N.; Lee, S.-H.; Kim, M.-M.; Kim, S.-K. Production of chitin oligosaccharides with different molecular weights and their antioxidant effect in RAW 264.7 cells. J. Funct. Foods 2009, 1, 188-198.
157. Je, J.-Y.; Kim, S.-K. Antioxidant activity of novel chitin derivative. Bioorg. Med. Chem. Lett. 2006, 16, 1884-1887. (Pubitemid 43267370)
158. Park, P.-J.; Je, J.-Y.; Kim, S.-K. Free radical scavenging activities of differently deacetylated chitosans using an ESR spectrometer. Carbohydr. Polym. 2004, 55, 17-22.
159. Je, J.-Y.; Cho, Y.-S.; Kim, S.-K. Characterization of (Aminoethyl)chitin/DNA Nanoparticle for Gene Delivery. Biomacromolecules 2006, 7, 3448-3451. (Pubitemid 46111800)
160. Xie, W.; Xu, P.; Liu, Q. Antioxidant activity of water-soluble chitosan derivatives. Bioorg. Med. Chem. Lett. 2001, 11, 1699-1701. (Pubitemid 32568301)
161. Bautista-Baños, S.; Hernández-López, M.; Bosquez-Molina, E.; Wilson, C.L. Effects of chitosan and plant extracts on growth of Colletotrichum gloeosporioides, anthracnose levels and quality of papaya fruit. Crop. Prot. 2003, 22, 1087-1092. (Pubitemid 37245065)
162. Tsai, G.J.; Su, W.H. Antibacterial activity of shrimp chitosan against Escherichia coli. J. Food Prot. 1999, 62, 239-243. (Pubitemid 29134017)
163. San-Lang, W.; Shih, I.-L.; Wang, C.-H.; Tseng, K.-C.; Chang, W.-T.; Twu, Y.-K.; Ro, J.-J.; Wang, C.-L. Production of antifungal compounds from chitin by Bacillus subtilis. Enzyme Microb. Technol. 2002, 31, 321-328. (Pubitemid 34786113)
164. Li, B.; Wang, X.; Chen, R.; Huangfu, W.; Xie, G. Antibacterial activity of chitosan solution against Xanthomonas pathogenic bacteria isolated from Euphorbia pulcherrima. Carbohydr. Polym. 2008, 72, 287-292. (Pubitemid 351192023)
165. El Ghaouth, A.; Arul, J.; Asselin, A.; Benhamou, N. Antifungal activity of chitosan on postharvest pathogens: induction of morphological and cytological alterations in Rhizopus stolonifer. Mycol. Res. 1992, 96, 769-779.
166. Young, D.H.; Kohle, H.; Kauss, H. Effect of Chitosan on Membrane Permeability of Suspension-Cultured Glycine max and Phaseolus vulgaris Cells. Plant Physiol. 1982, 70, 1449-1454.
167. De Smedt, S.C.; Demeester, J.; Hennink, W.E. Cationic Polymer Based Gene Delivery Systems. Pharm. Res. 2000, 17, 113-126.
168. Park, Y.K.; Park, Y.H.; Shin, B.A.; Choi, E.S.; Park, Y.R.; Akaike, T.; Cho, C.S. Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier. J. Controlled Release 2000, 69, 97-108.
169. Leong, K.W.; Mao, H.Q.; Truong-Le, V.L.; Roy, K.; Walsh, S.M.; August, J.T. DNA-polycation nanospheres as non-viral gene delivery vehicles. J. Controlled Release 1998, 53, 183-193. (Pubitemid 28218701)
170. Erbacher, P.; Zou, S.; Bettinger, T.; Steffan, A.-M.; Remy, J.-S. Chitosan-Based Vector/DNA Complexes for Gene Delivery: Biophysical Characteristics and Transfection Ability. Pharm. Res. 1998, 15, 1332-1339.
171. Begin, A.; Van Calsteren, M.R. Antimicrobial films produced from chitosan. Int. J. Biol. Macromol. 1999, 26, 63-67.
172. Ouattara, B.; Simard, R.E.; Piette, G.; BÈgin, A.; Holley, R.A. Inhibition of surface spoilage bacteria in processed meats by application of antimicrobial films prepared with chitosan. Int. J. Food Microbiol. 2000, 62, 139-148.
173. Dutta, P.K.; Tripathi, S.; Mehrotra, G.K.; Dutta, J. Perspectives for chitosan based antimicrobial films in food applications. Food Chem. 2009, 114, 1173-1182.
174. Day, R.B.; Okada, M.; Ito, Y.; Tsukada, K.; Zaghouani, H.; Shibuya, N.; Stacey, G. Binding site for chitin oligosaccharides in the soybean plasma membrane. Plant Physiol. 2001, 126, 1162-1173. (Pubitemid 32656803)
175. De Jong, A.J.; Heidstra, R.; Spaink, H.P.; Hartog, M.V.; Meijer, E.A.; Hendriks, T.; Schiavo, F.L.; Terzi, M.; Bisseling, T.; Van Kammen, A.; De Vries, S.C. Rhizobium Lipooligosaccharides Rescue a Carrot Somatic Embryo Mutant. Plant Cell 1993, 5, 615-620.
176. Felix, G.; Baureithel, K.; Boller, T. Desensitization of the perception system for chitin fragments in tomato cells. Plant Physiol. 1998, 117, 643-650. (Pubitemid 128652837)
177. Minami, E.; Kouchi, H.; Carlson, R.W.; Cohn, J.R.; Kolli, V.K.; Day, R.B.; Ogawa, T.; Stacey, G. Cooperative action of lipo-chitin nodulation signals on the induction of the early nodulin, ENOD2, in soybean roots. Mol. Plant Microbe Interact. 1996, 9, 574-583.
178. Ito, Y.; Kaku, H.; Shibuya, N. Identification of a high-affinity binding protein for N-acetylchitooligosaccharide elicitor in the plasma membrane of suspension-cultured rice cells by affinity labeling. Plant J. 1997, 12, 347-356. (Pubitemid 27389623)
179. Okada, M.; Matsumura, M.; Shibuya, N. Identification of a high-affinity binding protein for N-acetylchitooligosaccharide elicitor in theplasma membrane from rice leaf and root cells. J. Plant Physiol. 2001, 158, 121-124. (Pubitemid 32139811)
180. Koev, S.T.; Powers, M.A.; Park, J.J.; Yi, H.; Wu, L.; Bentley, W.E.; Payne, G.F.; Rubloff, G.W.; Ghodssi, R. Chitosan as a functional interface between biology and microsystems. In Bio Micro and Nanosystems Conference, 2006, BMN '06, 15-18 January 2006; pp. 82-82.
181. Cheng, J.C.; Pisano, A.P. Photolithographic Process for Integration of the Biopolymer Chitosan into Micro/Nanostructures. J. Microelectromech. Syst. 2008, 17, 402-409.
182. Park, I.; Cheng, J.; Pisano, A.P.; Lee, E.-S.; Jeong, J.-H. Low temperature, low pressure nanoimprinting of chitosan as a biomaterial for bionanotechnology applications. Appl. Phys. Lett. 2007, 90, 093902-093903.
183. Wang, B.; Tian, C.; Wang, L.; Wang, R.; Fu, H. Chitosan: a green carbon source for the synthesis of graphitic nanocarbon, tungsten carbide and graphitic nanocarbon/tungsten carbide composites. Nanotechnology 2010, 21, 025606.
184. Gopalan, N.K.; Dufresne, A. Crab Shell Chitin Whisker Reinforced Natural Rubber Nanocomposites. 1. Processing and Swelling Behavior. Biomacromolecules 2003, 4, 657-665. (Pubitemid 36701236)
185. Tanahashi, I.; Yoshida, A.; Nishino, A. Comparison of the Electrochemical Properties of Electric Double-Layer Capacitors with an Aqueous Electrolyte and with a Nonaqueous Electrolyte. Bull. Chem. Soc. Jpn. 1990, 63, 3611-3614.
186. Yamazaki, S.; Takegawa, A.; Kaneko, Y.; Kadokawa, J.-i.; Yamagata, M.; Ishikawa, M. An acidic cellulose-chitin hybrid gel as novel electrolyte for an electric double layer capacitor. Electrochem. Commun. 2009, 11, 68-70.
187. Sakaguchi, T.; Horikoshi, T.; Nakajima, A. Adsorption of Uranium by Chitin Phosphate and Chitosan Phosphate. Agric. Biol. Chem. 1981, 45, 2191-2195.
188. Franco, L.d.O.; Maia, R.d.C.C.; Porto, A.L.F.; Messias, A.S.; Fukushima, K.; Campos-Takaki, G.M.d. Heavy metal biosorption by chitin and chitosan isolated from Cunninghamella elegans (IFM 46109). Braz. J. Microbiol. 2004, 35, 243-247.
189. Jianlong, W.; Xinmin, Z.; Decai, D.; Ding, Z. Bioadsorption of lead(II) from aqueous solution by fungal biomass of Aspergillus niger. J. Biotechnol. 2001, 87, 273-277. (Pubitemid 32378759)
190. Hakim, L.; Sabarudin, A.; Oshita, K.; Oshima, M.; Motomizu, S. Synthesis of chitosan-based resins modified with tris(2-aminoethyl)amine moiety and its application to collection/concentration and determination of trace mercury by inductively coupled plasma atomic emission spectrometry. Talanta 2008, 76, 1256-1260.
191. Hakim, L.; Sabarudin, A.; Oshita, K.; Oshima, M.; Motomizu, S. Synthesis of cross-linked chitosan functionalized with threonine moiety and its application to on-line collection/concentration and determination of Mo, V and Cu. Talanta 2008, 74, 977-985.
192. Oshita, K.; Seo, K.; Sabarudin, A.; Oshima, M.; Takayanagi, T.; Motomizu, S. Synthesis of chitosan resin possessing a phenylarsonic acid moiety for collection/concentration of uranium and its determination by ICP-AES. Anal. Bioanal. Chem. 2008, 390, 1927-1932.
193. Hosoba, M.; Oshita, K.; Katarina, R.K.; Takayanagi, T.; Oshima, M.; Motomizu, S. Synthesis of novel chitosan resin possessing histidine moiety and its application to the determination of trace silver by ICP-AES coupled with triplet automated-pretreatment system. Anal. Chim. Acta 2009, 639, 51-56.
194. Hakim, L.; Sabarudin, A.; Oshima, M.; Motomizu, S. Synthesis of novel chitosan resin derivatized with serine diacetic acid moiety and its application to on-line collection/concentration of trace elements and their determination using inductively coupled plasma-atomic emission spectrometry. Anal. Chim. Acta 2007, 588, 73-81. (Pubitemid 46399627)
195. Peiselt da Silva, K.M.; Pais da silva, M.I. Copper sorption from diesel oil on chitin and chitosan polymers. Colloids Surf. A 2004, 237, 15-21.
196. Aksu, Z.m. Application of biosorption for the removal of organic pollutants: a review. Process Biochem. 2005, 40, 997-1026.
197. Wei, Z.G.; Sandstroröm, R.; Miyazaki, S. Shape-memory materials and hybrid composites for smart systems: Part I Shape-memory materials. J. Mater. Sci. 1998, 33, 3743-3762. (Pubitemid 128692134)
198. Zia, K.M.; Zuber, M.; Barikani, M.; Bhatti, I.A.; Khan, M.B. Surface characteristics of chitinbased shape memory polyurethane elastomers. Colloids Surf. B Biointerfaces 2009, 72, 248-252.
199. Zhang, G.; Wang, H.; Shi, J.; Wang, X.; Zheng, H.; Wong, G.; Clark, T.; Wang, W.; Wang, J.; Kang, L. Identification and characterization of insect-specific proteins by genome data analysis. BMC Genomics 2007, 8, 93.
200. Ieropoulos, I.; Melhuish, C.; Greenman, J.; Horsfield, I.; Hart, J. Energy autonomy in robots through Microbial Fuel Cells. In CiteSeerX - Scientific Literature Digital Library and Search Engine, The Pennsylvania State University, USA, 2004.
201. Giribet, G.; Okusu, A.; Lindgren, A.R.; Huff, S.W.; Schrodl, M.; Nishiguchi, M.K. Evidence for a clade composed of molluscs with serially repeated structures: monoplacophorans are related to chitons. Proc. Natl. Acad. Sci. USA 2006, 103, 7723-7728. (Pubitemid 43752848)
202. Evvyernie, D.; Yamazaki, S.; Morimoto, K.; Karita, S.; Kimura, T.; Sakka, K.; Ohmiya, K. Identification and characterization of Clostridium paraputrificum M-21, a chitinolytic, mesophilic and hydrogen-producing bacterium. J. Biosci. Bioeng. 2000, 89, 596-601.
203. Morimoto, K.; Kimura, T.; Sakka, K.; Ohmiya, K. Overexpression of a hydrogenase gene in Clostridium paraputrificum to enhance hydrogen gas production. FEMS Microbiol. Lett. 2005, 246, 229-234. (Pubitemid 40724434)
204. You, Y.; Park, W.H.; Ko, B.M.; Min, B.M. Effects of PVA sponge containing chitooligosaccharide in the early stage of wound healing. J. Mater. Sci. Mater. Med. 2004, 15, 297-301.
205. Choi, B.K.; Kim, K.Y.; Yoo, Y.J.; Oh, S.J.; Choi, J.H.; Kim, C.Y. In vitro antimicrobial activity of a chitooligosaccharide mixture against Actinobacillus actinomycetemcomitans and Streptococcus mutans. Int. J. Antimicrob. Agents 2001, 18, 553-557.
206. Kageyama, C.; Kato, K.; Iyozumi, H.; Inagaki, H.; Yamaguchi, A.; Furuse, K.; Baba, K. Photon emissions from rice cells elicited by N- acetylchitooligosaccharide are generated through phospholipid signaling in close association with the production of reactive oxygen species. Plant Physiol. Biochem. 2006, 44, 901-909. (Pubitemid 44918330)
207. Shen, K.T.; Chen, M.H.; Chan, H.Y.; Jeng, J.H.; Wang, Y.J. Inhibitory effects of chitooligosaccharides on tumor growth and metastasis. Food Chem. Toxicol. 2009, 47, 1864-1871.
208. Tsukada, K.; Matsumoto, T.; Aizawa, K.; Tokoro, A.; Naruse, R.; Suzuki, S.; Suzuki, M. Antimetastatic and growth-inhibitory effects of N-acetylchitohexaose in mice bearing Lewis lung carcinoma. Jpn. J. Cancer Res. 1990, 81, 259-265. (Pubitemid 20117319)
209. Wang, S.L.; Lin, H.T.; Liang, T.W.; Chen, Y.J.; Yen, Y.H.; Guo, S.P. Reclamation of chitinous materials by bromelain for the preparation of antitumor and antifungal materials. Bioresour. Technol. 2008, 99, 4386-4393.
210. Mizuochi, T.; Nakata, M. HIV infection and oligosaccharides: a novel approach to preventing HIV infection and the onset of AIDS. J. Infect. Chemother. 1999, 5, 190-195. (Pubitemid 30029640)
211. Chipman, D.M.; Grisaro, V.; Sharon, N. The binding of oligosaccharides containing N-acetylglucosamine and N-acetylmuramic acid to lysozyme. The specificity of binding subsites. J. Biol. Chem. 1967, 242, 4388-4394.
212. Austin, P.R.; Brine, C.J.; Castle, J.E.; Zikakis, J.P. Chitin: New facets of research. Science 1981, 212, 749-753.
213. Hayes, M.; Carney, B.; Slater, J.; Bruck, W. Mining marine shellfish wastes for bioactive molecules: chitin and chitosan - Part A: extraction methods. Biotechnol. J. 2008, 3, 871-877.
214. Kurita, K. Chitin and chitosan: functional biopolymers from marine crustaceans. Mar. Biotechnol. (NY) 2006, 8, 203-226.
215. Synowiecki, J.; Al-Khateeb, N.A. Production, properties, and some new applications of chitin and its derivatives. Crit. Rev. Food Sci. Nutr. 2003, 43, 145-171. (Pubitemid 38552306)
216. Tharanathan, R.N.; Kittur, F.S. Chitin - the undisputed biomolecule of great potential. Crit. Rev. Food Sci. Nutr. 2003, 43, 61-87.