Novel carboxymethyl chitin nanoparticles for cancer drug delivery applications

Carbohydrate Polymers

Volumn 79, Issue 4, 2010, Pages 1073-1079

  Dev, Ashish ^a   Mohan, Jithin C ^a   Sreeja, V ^a   Tamura, H ^b   Patzke, G R ^c   Hussain, F ^c   Weyeneth, S ^d   Nair, S V ^a   Jayakumar, R ^a  

^a AMRITA INSTITUTE OF MEDICAL SCIENCES   (India)

^b KANSAI UNIVERSITY   (Japan)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d PHYSIK INSTITUT DER UNIVERSITÄT ZÜRICH   (Switzerland)

Author keywords

Cancer drug delivery; Carboxymethyl chitin; Cytotoxicity; Ferromagnetic properties; Nanoparticles

Indexed keywords

5-FLUOROURACIL (5-FU); ANTICANCER DRUG; CANCER DRUG; CARBOXYMETHYL CHITIN; CARRIER SYSTEMS; DRUG RELEASE STUDY; ENCAPSULATION EFFICIENCY; FERROMAGNETIC PROPERTIES; FTIR; IN-VITRO; MOUSE CELLS; MTT ASSAYS; SEM; SUSTAINED DRUG RELEASE;

CALCIUM CHLORIDE; CHITIN; EMULSIFICATION; ENCAPSULATION; FERROMAGNETIC MATERIALS; FERROMAGNETISM; FOURIER TRANSFORM INFRARED SPECTROSCOPY; MAGNETIC PROPERTIES; NANOPARTICLES;

CONTROLLED DRUG DELIVERY;

EID: 73649116304     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2009.10.038     Document Type: Article

References (35)

1. Amano K., and Ito E. The action of lysozyme on partially deacetylated chitin. European Journal of Biochemistry 85 (1978) 97-104
2. Carreno-Gomez B., and Duncan R. Evaluation of the biological properties of soluble chitosan and chitosan microspheres. International Journal of Pharmaceutics 148 (1997) 231-240
3. Hata H., Onishi H., and Machida Y. Evaluation of carboxymethyl chitin as a drug carrier: Effect of the deacetylation degree on the biodegradation and biodisposition characteristics in mice. STP Pharmaceutical Sciences 9 (1999) 115-121
4. Hata H., Onishi H., and Machida Y. Preparation of CM-chitin microspheres by complexation with iron (III) in w/o emulsion and their biodisposition characteristics in mice. Biomaterials 21 (2000) 1779-1788
5. Inez M., Lubben V.D., Verhoef J.C., Borchard G., and Junginger H.E. Chitosan and its derivatives in mucosal drug and vaccine delivery. European Journal of Pharmaceutical Science 14 (2001) 201-207
6. Jayakumar R., Nwe N., Tokura S., and Tamura H. Sulfated chitin and chitosan as novel biomaterials. International Journal of Biological Macromolecules 40 (2007) 175-181
7. Jayakumar R., Prabaharan M., Reis R.L., and Mano J.F. Graft copolymerized chitosan - present status and applications. Carbohydrate Polymers 62 (2005) 142-158
8. Kamiyama K., Onishi H., and Machida Y. Biodisposition characteristics of N-succinyl-chitosan and 6-O-glycol-chitosan in normal and tumor-bearing mice. Biological Pharmaceutical Bulletin 22 (1999) 179-186
9. Kanke M., Simmons G.H., Weiss D.L., Bivins B.A., and Deluca P.P. Clearance of 141Ce-labeled microspheres from blood and distribution in specific organs following intravenous and intraarterial administration in beagle dogs. Journal of Pharmaceutical Sciences 69 (1980) 755-762
10. Kishimoto S., and Tamaki K. Immunohistochemical and histochemical observations in the process of burn wound healing guinea pig skin under chitin membrane dressing. Acta Dermatol-Kyoto 82 (1987) 471-479
11. Lee K.Y., Ha W.S., and Park W.H. Blood compatibility and biodegradability of partially N-acetylated chitosan derivatives. Biomaterials 16 (1995) 1211-1216
12. Mi F.L., Chen C.T., Tseng Y.C., Kuan C.Y., and Shyu S.S. Iron (III)-carboxymethyl chitin microsphere for the pH-sensitive release of 6-mercaptopurine. Journal of Controlled Release 44 (1997) 19-32
13. Muzzarelli R.A.A. Carboxymethylated chitin and chitosans. Carbohyrate Polymers 8 (1988) 1-21
14. Nakamura F., Onishi H., Machida Y., and Nagai T. Lysozymecatalyzed degradation properties of the conjugates between chitosans having some deacetylation degrees and methotrexate. Yakuzaigaku 52 (1992) 59-67
15. Nishimura S., Nishi N., and Tokura S. Bioactive chitin derivatives. Activation of mouse-peritoneal macrophages by O-(carboxymethyl)chitins. Carbohyrate Research 146 (1986) 251-258
16. Ouchi T., Banba T., Fujimoto M., and Hamamoto S. Synthesis and antitumor activity of chitosan carrying 5-Fluorouracils. Makromolecular Chemistry 190 (1989) 1817-1825
17. Ouchi T., Banba T., Matsumoto T., Suzuki S., and Suzuki M. Antitumor activity of chitosan and chitin immobilized 5-fluorouracils through hexamethylene spacers via carbanoyl bonds. Journal of Bioactive and Compatible Polymers 4 (1989) 362-371
18. Pangburn S.H., Trescony P.V., and Heller J. Lysozyme degradation of partially deacetylated chitin, its films and hydrogels. Biomaterials 3 (1982) 105-108
19. Prabaharan, and Mano J.F. Chitosan-based particles for controlled drug delivery systems. Drug Delivery 12 (2005) 41-57
20. Prashanth H.K.V., and Tharanathan R.N. Chitin/chitosan: Modifications and their unlimited application potential-an overview. Trends in Food Science and Technology 18 (2007) 117-131
21. Shin I.G., Kim S.Y., Lee Y.M., Cho C.S., and Sung Y.K. Methoxy poly(ethylene glycol)/E-caprolactone amphiphilic block copolymeric micelle containing indomethacin. I. Preparation and characterization. Journal of Controlled Release 51 (1998) 1-11
22. Song Y., Onishi H., Machida Y., and Nagai T. Particle characteristics of carboxymethyl-chitin mitomycin C conjugate and N-succinylchitosan mitomycin C conjugate and their distribution and histological effect on some tissues after intravenous administration. STP Pharmaceutical Sciences 5 (1995) 162-170
23. Song Y., Onishi H., and Nagai T. Synthesis and drug-release characteristics of the conjugates of mitomycin C with N-succinyl-chitosan and carboxymethyl-chitin. Chemical Pharmaceutical Bulletin 40 (1992) 2822-2825
24. Song Y., Onishi H., and Nagai T. Pharmacokinetic characteristics and antitumor activity of the N-succinyl-chitosan mitomycin C conjugate and the carboxymethyl-chitin mitomycin C conjugate. Biological Pharmaceutical Bulletin 16 (1993) 48-54
25. Song Y., Onishi H., and Nagai T. Conjugate of mitomycin C with N-succinyl-chitosan: In vitro release properties, toxicity and antitumor activity. International Journal of Pharmaceutics 98 (1993) 121-130
26. Song Y., Onishi H., and Nagai T. Toxicity and antitumor activity of the conjugate of mitomycin C with carboxymethyl-chitin. Yakuzaigaku 53 (1993) 141-147
27. Sugibayashi K., Morimoto Y., Nadai T., Kato Y., Hasegawa A., and Arita T. Drug-carrier property of albumin microspheres in chemotherapy. II. Preparation and tissue distribution in mice of microsphere-entrapped 5-fluorouracil. Chemical Pharmaceutical Bulletin 25 (1979) 204-209
28. Wang X., Lin J., Zhang X., Liu Q., Xu Q., Tan R.X., et al. 5-Fluorouracil-cisplatin adducts with potential antitumor activity. Journal of Inorganic Biochemistry 94 (2003) 186-192
29. Watanabe K., Saiki I., Matsumoto Y., Azuma I., Seo H., Okuyama H., et al. Antimetastatic activity of neocarzinostatin incorporated into controlled release gels of carboxymethyl chitin. Carbohydrate Polymers 17 (1992) 29-37
30. Watanabe K., Saiki I., Uraki I., Tokura S., and Azuma I. 6-O-carboxymethyl chitin (CM-chitin) as a drug carrier. Chemical Pharmaceutical Bulletin 38 (1990) 506-509
31. Yao C., Liu X., and Risen W.M. Novel Ferromagnetic aerogel composite materials with nanoparticles formation and chemistry in response to light. Material Research Society Symposium Proceedings 888 (2006) 05-07
32. Yasutomi Y., Nakakita N., Shioya N., and Kuroyanagi Y. Development of bio-synthetic wound dressing with drug delivery capability composed of polyurethane membrane and biological spongy material: Clinical evaluation. Nessho 19 (1993) 102-116
33. Yoshino T., Machida Y., Onishi H., and Nagai T. Characteristics of drug loading, drug release and degradation of chitosan microspheres prepared using the dry-in-oil method. STP Pharmaceutical Science 6 (1996) 122-128
34. Yoshioka T., Hashida M., Muranishi S., and Sezaki H. Specific delivery of mitomycin C to the liver, spleen and lung: Nano- and microspherical carriers of gelatin. International Journal of Pharmaceutics 31 (1981) 131-141
35. Zhang D.Y., Shen X.Z., Wang J.Y., Dong L., Zheng Y.L., and Wu L.L. Preparation of chitosan-polyaspartic acid-5-fluorouracil nanoparticles and its anti-carcinoma effect on tumor growth in nude mice. World Journal of Gastroenterology 22 (2008) 3554-3562