Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-linked β-N-acetylglucosamine in 3T3-L1 adipocytes

Journal of Biological Chemistry

Volumn 285, Issue 8, 2010, Pages 5204-5211

  Whelan, Stephen A ^a,b   Dias, Wagner B ^a,c   Thiruneelakantapillai, Lakshmanan ^a,d   Daniel Lane, M ^a   Hart, Gerald W ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d Momenta Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3T3-L1 ADIPOCYTES; ADIPOCYTES; BINDING MOTIF; CONCOMITANT REDUCTION; CONTROL POINT; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RESISTANCE; INSULIN SIGNALING; INSULIN TREATMENT; N-ACETYLGLUCOSAMINE; O-LINKED; PHOSPHOINOSITIDE 3-KINASE; TYROSINE PHOSPHORYLATION;

AMINO ACIDS; PHOSPHATASES; PHOSPHORYLATION; PROTEINS; SIGNALING; SUBSTRATES;

INSULIN;

ENZYME; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; N ACETYLGLUCOSAMINE; N ACETYLGLUCOSAMINE TRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; UNCLASSIFIED DRUG; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN; IRS1 PROTEIN, MOUSE; IRS2 PROTEIN, HUMAN; IRS2 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL TRANSFERRING) KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; INSULIN RESISTANCE; INSULIN SIGNALING; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3-L1 CELLS; ACETYLGLUCOSAMINE; ADIPOCYTES; AMINO ACID MOTIFS; ANIMALS; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MICE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 77949332132     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.077818     Document Type: Article

References (58)

1. Whelan, S. A., and Hart, G. W. (2003) Circ. Res. 93, 1047-1058
2. Wells, L., Vosseller, K., and Hart, G. W. (2001) Science 291, 2376-2378
3. Zachara, N. E., and Hart, G. W. (2006) Biochim. Biophys. Acta 1761, 599-617
4. Comer, F. I., and Hart, G. W. (2001) Biochemistry 40, 7845-7852
5. Lefebvre, T., Alonso, C., Mahboub, S., Dupire, M. J., Zanetta, J. P., Caillet-Boudin, M. L., and Michalski, J. C. (1999) Biochim. Biophys. Acta 1472, 71-81
6. Wang, Z., Gucek, M., and Hart, G. W. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 13793-13798
7. Chou, T. Y., Hart, G. W., and Dang, C. V. (1995) J. Biol. Chem. 270, 18961-18965
8. Kelly, W. G., Dahmus, M. E., and Hart, G. W. (1993) J. Biol. Chem. 268, 10416-10424
9. Arnold, C. S., Johnson, G. V., Cole, R. N., Dong, D. L., Lee, M., and Hart, G. W. (1996) J. Biol. Chem. 271, 28741-28744
10. Tao, G. Z., Kirby, C., Whelan, S. A., Rossi, F., Bi, X., MacLaren, M., Gentalen, E., O'Neill, R. A., Hart, G. W., and Omary, M. B. (2006) Biochem. Biophys. Res. Commun. 351, 708-712
11. Kreppel, L. K., Blomberg, M. A., and Hart, G. W. (1997) J. Biol. Chem. 272, 9308-9315
12. Lubas, W. A., Frank, D. W., Krause, M., and Hanover, J. A. (1997) J. Biol. Chem. 272, 9316-9324
13. Whelan, S. A., Lane, M. D., and Hart, G. W. (2008) J. Biol. Chem. 283, 21411-21417
14. Song, M., Kim, H. S., Park, J. M., Kim, S. H., Kim, I. H., Ryu, S. H., and Suh, P. G. (2008) Cell. Signal. 20, 94-104
15. Yki-Järvinen, H., Virkamäki, A., Daniels, M. C., McClain, D., and Gottschalk, W. K. (1998) Metabolism 47, 449-455
16. Vosseller, K., Wells, L., Lane, M. D., and Hart, G. W. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 5313-5318
17. Federici, M., Menghini, R., Mauriello, A., Hribal, M. L., Ferrelli, F., Lauro, D., Sbraccia, P., Spagnoli, L. G., Sesti, G., and Lauro, R. (2002) Circulation 106, 466-472
18. Patti, M. E., Virkamäki, A., Landaker, E. J., Kahn, C. R., and Yki-Järvinen, H. (1999) Diabetes 48, 1562-1571
19. Haltiwanger, R. S., Grove, K., and Philipsberg, G. A. (1998) J. Biol. Chem. 273, 3611-3617
20. Horsch, M., Hoesch, L., Vasella, A., and Rast, D. M. (1991) Eur. J. Biochem. 197, 815-818
21. Buse, M. G. (2006) Am. J. Physiol. Endocrinol. Metab. 290, E1-E8
22. Ball, L. E., Berkaw, M. N., and Buse, M. G. (2006) Mol. Cell. Proteomics 5, 313-323
23. Lima, F. B., Thies, R. S., and Garvey, W. T. (1991) Endocrinology 128, 2415-2426
24. Forsythe, M. E., Love, D. C., Lazarus, B. D., Kim, E. J., Prinz, W. A., Ashwell, G., Krause, M. W., and Hanover, J. A. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 11952-11957
25. Yang, X., Ongusaha, P. P., Miles, P. D., Havstad, J. C., Zhang, F., So, W. V., Kudlow, J. E., Michell, R. H., Olefsky, J. M., Field, S. J., and Evans, R. M. (2008) Nature 451, 964-969
26. White, M. F. (1997) Diabetologia 40, Suppl. 2, S2-S17
27. Esposito, D. L., Li, Y., Cama, A., and Quon, M. J. (2001) Endocrinology 142, 2833-2840
28. Rordorf-Nikolic, T., Van Horn, D. J., Chen, D., White, M. F., and Backer, J. M. (1995) J. Biol. Chem. 270, 3662-3666
29. Storz, P., and Toker, A. (2002) Front. Biosci. 7, d886-d902
30. Toker, A., and Newton, A. C. (2000) Cell 103, 185-188
31. Nicholson, K. M., and Anderson, N. G. (2002) Cell. Signal. 14, 381-395
32. Stokoe, D., Stephens, L. R., Copeland, T., Gaffney, P. R., Reese, C. B., Painter, G. F., Holmes, A. B., McCormick, F., and Hawkins, P. T. (1997) Science 277, 567-570
33. Le Good, J. A., Ziegler, W. H., Parekh, D. B., Alessi, D. R., Cohen, P., and Parker, P. J. (1998) Science 281, 2042-2045
34. Shaw, M., Cohen, P., and Alessi, D. R. (1997) FEBS Lett. 416, 307-311
35. Calera, M. R., Martinez, C., Liu, H., Jack, A. K., Birnbaum, M. J., and Pilch, P. F. (1998) J. Biol. Chem. 273, 7201-7204
36. Kupriyanova, T. A., and Kandror, K. V. (1999) J. Biol. Chem. 274, 1458-1464
37. Standaert, M. L., Bandyopadhyay, G., Sajan, M. P., Cong, L., Quon, M. J., and Farese, R. V. (1999) J. Biol. Chem. 274, 14074-14078
38. Kotani, K., Ogawa, W., Matsumoto, M., Kitamura, T., Sakaue, H., Hino, Y., Miyake, K., Sano, W., Akimoto, K., Ohno, S., and Kasuga, M. (1998) Mol. Cell Biol. 18, 6971-6982
39. Student, A. K., Hsu, R. Y., and Lane, M. D. (1980) J. Biol. Chem. 255, 4745-4750
40. Whelan, S. A., and Hart, G. W. (2006) Methods Enzymol. 415, 113-133
41. Dias, W. B., Cheung, W. D., Wang, Z., and Hart, G. W. (2009) J. Biol. Chem. 284, 21327-21337
42. Gross, B. J., Kraybill, B. C., and Walker, S. (2005) J. Am. Chem. Soc. 127, 14588-14589
43. Kohanski, R. A., Frost, S. C., and Lane, M. D. (1986) J. Biol. Chem. 261, 12272-12281
44. Kudlow, J. E. (2006) J. Cell Biochem. 98, 1062-1075
45. Hanover, J. A. (2001) FASEB J. 15, 1865-1876
46. Love, D. C., and Hanover, J. A. (2005) Sci. STKE 2005, re13
47. Wells, L., Whelan, S. A., and Hart, G. W. (2003) Biochem. Biophys. Res. Commun. 302, 435-441
48. Slawson, C., Housley, M. P., and Hart, G. W. (2006) J. Cell Biochem. 97, 71-83
49. Park, S. Y., Ryu, J., and Lee, W. (2005) Exp. Mol. Med. 37, 220-229
50. Gandy, J. C., Rountree, A. E., and Bijur, G. N. (2006) FEBS Lett. 580, 3051-3058
51. Yanagisawa, M., and Yu, R. K. (2009) J. Neurosci. Res. 87, 3535-3545
52. Arias, E. B., Kim, J., and Cartee, G. D. (2004) Diabetes 53, 921-930
53. Klein, A. L., Berkaw, M. N., Buse, M. G., and Ball, L. E. (2009) Mol. Cell Proteomics 8, 2733-2745
54. Wells, L., Vosseller, K., and Hart, G. W. (2003) Cell Mol. Life Sci. 60, 222-228
55. Robinson, K. A., Ball, L. E., and Buse, M. G. (2007) Am. J. Physiol. Endocrinol. Metab. 292, E884-E890
56. Nelson, B. A., Robinson, K. A., and Buse, M. G. (2000) Diabetes 49, 981-991
57. Housley, M. P., Rodgers, J. T., Udeshi, N. D., Kelly, T. J., Shabanowitz, J., Hunt, D. F., Puigserver, P., and Hart, G. W. (2008) J. Biol. Chem. 283, 16283-16292
58. Housley, M. P., Udeshi, N. D., Rodgers, J. T., Shabanowitz, J., Puigserver, P., Hunt, D. F., and Hart, G. W. (2009) J. Biol. Chem. 284, 5148-5157