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Volumn 21, Issue 1, 2010, Pages 229-247

Modulation of hydrogen peroxide and acrolein-induced oxidative stress, mitochondrial dysfunctions and redox regulated pathways by the bacopa monniera extract: Potential implication in Alzheimer's disease

Author keywords

Alzheimer's disease; Bacopa monniera; mitochondria; oxidative stress; redox regulation

Indexed keywords

ACROLEIN; BACOPA MONNIERI EXTRACT; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; GLUTATHIONE; LACTATE DEHYDROGENASE; PLANT EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

EID: 77954982065     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-091729     Document Type: Article
Times cited : (45)

References (85)
  • 1
    • 71849095133 scopus 로고    scopus 로고
    • Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases
    • Gibson GE, Starkov A, Blass JP, Ratan RR, M Beal MF (2010) Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. Biochim Biophys Acta 1802, 122-134.
    • (2010) Biochim Biophys Acta , pp. 122-134
    • Gibson, G.E.1    Starkov, A.2    Blass, J.P.3    Ratan, R.R.4    Beal, M.F.M.5
  • 2
    • 67849097738 scopus 로고    scopus 로고
    • Oxidative stress in vascular dementia and Alzheimer's disease: A common pathology
    • Bennett S, Grant MM, Aldred S (2009) Oxidative Stress in Vascular Dementia and Alzheimer's disease: A Common Pathology. J Alzheimers Dis 17, 245-257.
    • (2009) J Alzheimers Dis , vol.17 , pp. 245-257
    • Bennett, S.1    Grant, M.M.2    Aldred, S.3
  • 4
    • 0036591849 scopus 로고    scopus 로고
    • Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress
    • Butterfield DA, Lauderback CM (2002) Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radic Biol Med 32, 1050-1060.
    • (2002) Free Radic Biol Med , vol.32 , pp. 1050-1060
    • Butterfield, D.A.1    Lauderback, C.M.2
  • 5
    • 38049010515 scopus 로고    scopus 로고
    • Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
    • Lovell MA, Markesbery WR (2007) Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Res 35, 7497-7504.
    • (2007) Nucleic Acids Res , vol.35 , pp. 7497-7504
    • Ma, L.1    Markesbery, W.R.2
  • 7
    • 0035112495 scopus 로고    scopus 로고
    • Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
    • Lovell MA, Xie C, Markesbery WR (2001) Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol Aging 22, 187-194.
    • (2001) Neurobiol Aging , vol.22 , pp. 187-194
    • Ma, L.1    Xie, C.2    Markesbery, W.R.3
  • 8
    • 33744935554 scopus 로고    scopus 로고
    • Increased levels of4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease
    • Williams TI, Lynn BC, Markesbery WR, Lovell MA (2006) Increased levels of4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease. Neurobiol Aging 27, 1094-1099.
    • (2006) Neurobiol Aging , vol.27 , pp. 1094-1099
    • Williams, T.I.1    Lynn, B.C.2    Markesbery, W.R.3    Ma, L.4
  • 9
    • 0032905632 scopus 로고    scopus 로고
    • Protein-bound acrolein: A novel marker of oxidative stress in Alzheimer's disease
    • Calingasan NY, Uchida K, Gibson GE (1999) Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease. J Neurochem 72, 751-756.
    • (1999) J Neurochem , vol.72 , pp. 751-756
    • Calingasan, N.Y.1    Uchida, K.2    Gibson, G.E.3
  • 10
    • 24944565214 scopus 로고    scopus 로고
    • Development of a method for quantification ofacrolein-deoxyguanosine adducts in DNA using isotope dilution-capillary LC/MS/MS and its application to human brain tissue
    • Liu X, Lovell MA, Lynn BC (2005) Development of a method for quantification ofacrolein-deoxyguanosine adducts in DNA using isotope dilution-capillary LC/MS/MS and its application to human brain tissue. Anal Chem 77, 5982-5989.
    • (2005) Anal Chem , vol.77 , pp. 5982-5989
    • Liu, X.1    Ma, L.2    Lynn, B.C.3
  • 11
    • 33744460225 scopus 로고    scopus 로고
    • Detection and quantification of endogenous cyclic DNA adducts derived from trans-4-hydroxy-2-nonenal in human brain tissue by isotope dilution capillary liquid chromatography nanoelectrospray tandem mass spectrometry
    • Liu X, Lovell MA, Lynn BC (2006) Detection and quantification of endogenous cyclic DNA adducts derived from trans-4-hydroxy-2-nonenal in human brain tissue by isotope dilution capillary liquid chromatography nanoelectrospray tandem mass spectrometry. Chem Res Toxicol 19, 710-718.
    • (2006) Chem Res Toxicol , vol.19 , pp. 710-718
    • Liu, X.1    Ma, L.2    Lynn, B.C.3
  • 12
    • 0035872474 scopus 로고    scopus 로고
    • Mechanisms by which metals promote events connected to neurodegenerative diseases
    • Campbell A, Smith MA, Sayre LM, Bondy SC, Perry G (2001). Mechanisms by which metals promote events connected to neurodegenerative diseases. Brain Res Bull 55, 125-132.
    • (2001) Brain Res Bull , vol.55 , pp. 125-132
    • Campbell, A.1    Ma, S.2    Sayre, L.M.3    Bondy, S.C.4    Perry, G.5
  • 13
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid beta protein toxicity
    • Behl C, Davis JB, Lesley R, Schubert D (1994) Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 77, 817-827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 15
    • 70149093436 scopus 로고    scopus 로고
    • Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
    • Yao J, Irwin RW, Zhao L, Nilsen J, Hamilton RT, Brin-ton RD (2009) Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 106, 14670-14675.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14670-14675
    • Yao, J.1    Irwin, R.W.2    Zhao, L.3    Nilsen, J.4    Hamilton, R.T.5    Brin-Ton, R.D.6
  • 16
    • 0036591852 scopus 로고    scopus 로고
    • Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease
    • Tabner BJ, Turnbull S, El-Agnaf OM, Allsop D (2002) Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease. Free Radic Biol Med 32, 1076-1083.
    • (2002) Free Radic Biol Med , vol.32 , pp. 1076-1083
    • Tabner, B.J.1    Turnbull, S.2    El-Agnaf, O.M.3    Allsop, D.4
  • 17
    • 0030983079 scopus 로고    scopus 로고
    • Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease
    • Kaltschmidt B, Uherek M, Volk B, Baeuerle PA, Kaltschmidt C (1997) Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc Natl Acad Sci USA 94, 2642-2647.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2642-2647
    • Kaltschmidt, B.1    Uherek, M.2    Volk, B.3    Baeuerle, P.A.4    Kaltschmidt, C.5
  • 18
    • 9644294200 scopus 로고    scopus 로고
    • NF-kappaB precursor, p105, and NF-kappaB inhibitor, Ikap-paBgamma, are both elevated in Alzheimer disease brain
    • Huang Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2005) NF-kappaB precursor, p105, and NF-kappaB inhibitor, Ikap-paBgamma, are both elevated in Alzheimer disease brain. Neu-rosciLett 373, 115-118.
    • (2005) Neu-rosciLett , vol.373 , pp. 115-118
    • Huang, Y.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4    Gong, C.X.5
  • 19
    • 9644275598 scopus 로고    scopus 로고
    • Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease
    • Sung S, Yang H, Uryu K, Lee EB, Zhao L, Shineman D, Trojanowski JQ, Lee VM, Pratico D (2004) Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. Am J Pathol 165, 2197-2206.
    • (2004) Am J Pathol , vol.165 , pp. 2197-2206
    • Sung, S.1    Yang, H.2    Uryu, K.3    Lee, E.B.4    Zhao, L.5    Shineman, D.6    Trojanowski, J.Q.7    Lee, V.M.8    Pratico, D.9
  • 20
    • 67849096609 scopus 로고    scopus 로고
    • Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice
    • Echeverria V, Burgess S, Gamble-George J, Zeitlin R, Lin X, Cao C, Arendash GW (2009) Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice. Neuroscience 162, 1220-1231.
    • (2009) Neuroscience , vol.162 , pp. 1220-1231
    • Echeverria, V.1    Burgess, S.2    Gamble-George, J.3    Zeitlin, R.4    Lin, X.5    Cao, C.6    Arendash, G.W.7
  • 21
    • 33745985711 scopus 로고    scopus 로고
    • ERK1/2 activation mediates Aft oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures
    • Chong YH, Shin YJ, Lee EO, Kayed R, Glabe CG, Tenner AJ (2006) ERK1/2 activation mediates Aft oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures. J Biol Chem 281, 20315-20325.
    • (2006) J Biol Chem , vol.281 , pp. 20315-20325
    • Chong, Y.H.1    Shin, Y.J.2    Lee, E.O.3    Kayed, R.4    Glabe, C.G.5    Tenner, A.J.6
  • 22
    • 0347948518 scopus 로고    scopus 로고
    • Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: Role of ERK1/2 in H2O2-induced cell death
    • Ruffels J, Griffin M, Dickenson JM (2004) Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: role of ERK1/2 in H2O2-induced cell death. Eur J Pharmacol 483, 163-173.
    • (2004) Eur J Pharmacol , vol.483 , pp. 163-173
    • Ruffels, J.1    Griffin, M.2    Dickenson, J.M.3
  • 25
    • 0035934224 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase cascade and phosphorylation of cytoskeletal proteins after neurone-specific activation of p21ras. II. Cytoskeletal proteins and dendritic morphology
    • DOI 10.1016/S0306-4522(01)00246-9, PII S0306452201002469
    • Holzer M, Rodel L, Seeger G, Gartner U, Narz F, Janke C, Heumann R, Arendt T (2001) Activation of mitogen-activated protein kinase cascade and phosphorylation of cytoskeletal proteins after neurone-specific activation of p21ras. II. Cy-toskeletal proteins and dendritic morphology. Neuroscience 105, 1041-1054. (Pubitemid 32786816)
    • (2001) Neuroscience , vol.105 , Issue.4 , pp. 1041-1054
    • Holzer, M.1    Rodel, L.2    Seeger, G.3    Gartner, U.4    Narz, F.5    Janke, C.6    Heumann, R.7    Arendt, T.8
  • 26
    • 85062139768 scopus 로고
    • Tau phosphorylation in brain slices: Pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated protein kinase
    • Garver TD, Oyler GA, Harris KA, Polavarapu R, Damuni Z, Lehman RA, Billingsley ML (1995) Tau phosphorylation in brain slices: pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated protein kinase. Mol Pharmacol 47, 745-756.
    • (1995) Mol Pharmacol , vol.47 , pp. 745-756
    • Garver, T.D.1    Oyler, G.A.2    Harris, K.A.3    Polavarapu, R.4    Damuni, Z.5    Lehman, R.A.6    Billingsley, M.L.7
  • 28
    • 0043204252 scopus 로고    scopus 로고
    • Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function
    • Howes MJ, Houghton PJ (2003) Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function. Pharmacol Biochem Behav 75, 513-527.
    • (2003) Pharmacol Biochem Behav , vol.75 , pp. 513-527
    • Howes, M.J.1    Houghton, P.J.2
  • 29
    • 16344365853 scopus 로고    scopus 로고
    • Bacopa monniera, a reputed nootropic plant: An overview
    • Russo A, Borrelli F (2005) Bacopa monniera, a reputed nootropic plant: an overview. Phytomed 12, 305-317.
    • (2005) Phytomed , vol.12 , pp. 305-317
    • Russo, A.1    Borrelli, F.2
  • 30
    • 53649103663 scopus 로고    scopus 로고
    • Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture
    • Limpeanchob N, Jaipan S, Rattanakaruna S, Phrompittayarat W, Ingkaninan K (2008) Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture. J Ethnopharmacol 120, 112-117.
    • (2008) J Ethnopharmacol , vol.120 , pp. 112-117
    • Limpeanchob, N.1    Jaipan, S.2    Rattanakaruna, S.3    Phrompittayarat, W.4    Ingkaninan, K.5
  • 32
    • 0037441753 scopus 로고    scopus 로고
    • The establishment of a reliable cytotoxic system with SK-N-SH neuroblastoma cell culture
    • Ba F, Pang PK, Benishin CG (2003) The establishment of a reliable cytotoxic system with SK-N-SH neuroblastoma cell culture. J Neurosci Methods 123, 11-22.
    • (2003) J Neurosci Methods , vol.123 , pp. 11-22
    • Ba, F.1    Pang, P.K.2    Benishin, C.G.3
  • 34
    • 0027249667 scopus 로고
    • A new fluorometric assay for cytotoxicity measurements in vitro
    • Page B, Page M, Noel C (1993) A new fluorometric assay for cytotoxicity measurements in vitro. Int J Oncol 3, 473-476.
    • (1993) Int J Oncol , vol.3 , pp. 473-476
    • Page, B.1    Page, M.2    Noel, C.3
  • 35
    • 0033856957 scopus 로고    scopus 로고
    • Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
    • O'Brien J, Wilson I, Orton T, Pognan F (2000) Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur J Biochem 267, 5421-5426.
    • (2000) Eur J Biochem , vol.267 , pp. 5421-5426
    • O'Brien, J.1    Wilson, I.2    Orton, T.3    Pognan, F.4
  • 36
    • 33746030280 scopus 로고    scopus 로고
    • An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates
    • Luo C, Wang X, Long J, Liu J (2006) An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates. J Biochem Biophys Methods 68, 101-111.
    • (2006) J Biochem Biophys Methods , vol.68 , pp. 101-111
    • Luo, C.1    Wang, X.2    Long, J.3    Liu, J.4
  • 37
    • 77950520685 scopus 로고    scopus 로고
    • Dynamics of H2O2 availability to ARPE-19 cultures in models of oxidative stress
    • Kaczara P, Sarna T, Burke JM (2010) Dynamics of H2O2 availability to ARPE-19 cultures in models of oxidative stress. Free Radic Biol Med 48, 1064-1070.
    • Free Radic Biol Med , vol.48 , pp. 1064-1070
    • Kaczara, P.1    Sarna, T.2
  • 38
    • 56049093212 scopus 로고    scopus 로고
    • Protective effect of Pycnogenol in human neuroblastoma SH-SY5Y cells following acrolein-induced cytotoxicity
    • Mubeen AA, Jeffrey NK, Stephen WS (2008) Protective effect of Pycnogenol in human neuroblastoma SH-SY5Y cells following acrolein-induced cytotoxicity. Free Radic Biol Med 45, 1510-1519.
    • (2008) Free Radic Biol Med , vol.45 , pp. 1510-1519
    • Mubeen, A.A.1    Jeffrey, N.K.2    Stephen, W.S.3
  • 39
    • 70450176923 scopus 로고    scopus 로고
    • Acrolein scavenging: Apotentialnov-el mechanism of attenuating oxidative stress following spinal cord injury
    • HamannK, Shi R (2009) Acrolein scavenging: apotentialnov-el mechanism of attenuating oxidative stress following spinal cord injury. J Neurochem 111, 1348-1356.
    • (2009) J Neurochem , vol.111 , pp. 1348-1356
    • Hamannk Shi, R.1
  • 40
    • 0030721736 scopus 로고    scopus 로고
    • Oxidation of 2/, 7/-dichlorofluorescin by peroxynitrite
    • Kooy NW, Royall JA, Ischiropoulos H (1997) Oxidation of 2/, 7/-dichlorofluorescin by peroxynitrite. Free Radic Res 27, 245-254.
    • (1997) Free Radic Res , vol.27 , pp. 245-254
    • Kooy, N.W.1    Royall, J.A.2    Ischiropoulos, H.3
  • 41
    • 33745323369 scopus 로고    scopus 로고
    • Visualization of nitric oxide in living cells by a copper-based fluorescent probe
    • Lim HM, Xu D, Lippard SJ (2006) Visualization of nitric oxide in living cells by a copper-based fluorescent probe. Nat Chem Biol 2, 375-380.
    • (2006) Nat Chem Biol , vol.2 , pp. 375-380
    • Lim, H.M.1    Xu, D.2    Lippard, S.J.3
  • 43
    • 68949173804 scopus 로고    scopus 로고
    • Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells
    • Roy J, Pallepati P, Bettaieb A, Tanel A, Averill-Bates DA (2009) Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells. Chem Biol Interact 181, 154-167.
    • (2009) Chem Biol Interact , vol.181 , pp. 154-167
    • Roy, J.1    Pallepati, P.2    Bettaieb, A.3    Tanel, A.4    Averill-Bates, D.A.5
  • 44
    • 24644490031 scopus 로고    scopus 로고
    • Acrolein-induced cell death in PC12 cells: Role of mitochondria-mediated oxidative stress
    • Luo J, Robinson JP, Shi R (2005) Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress. Neurochem Int 47, 449-457.
    • (2005) Neurochem Int , vol.47 , pp. 449-457
    • Luo, J.1    Robinson, J.P.2    Shi, R.3
  • 47
    • 44449151542 scopus 로고    scopus 로고
    • Activation of the lifespan regulator p66Shc through reversible disulfide bond formation
    • Gertz M, Fischer F, Wolters D, Steegborn C (2008) Activation of the lifespan regulator p66Shc through reversible disulfide bond formation. Proc Nat Acad Sci USA 105, 5705-5709.
    • (2008) Proc Nat Acad Sci USA , vol.105 , pp. 5705-5709
    • Gertz, M.1    Fischer, F.2    Wolters, D.3    Steegborn, C.4
  • 50
    • 47749147258 scopus 로고    scopus 로고
    • Hydrogen peroxide promotes after production through JNK-dependent activation of g-secretase
    • Shen C, Chen Y, Liu H, Zhang K, Zhang T, Lin A, Jing N (2008) Hydrogen peroxide promotes after production through JNK-dependent activation of g-secretase. J Biol Chem 283, 17721-17730.
    • (2008) J Biol Chem , vol.283 , pp. 17721-17730
    • Shen, C.1    Chen, Y.2    Liu, H.3    Zhang, K.4    Zhang, T.5    Lin, A.6    Jing, N.7
  • 51
    • 70349492687 scopus 로고    scopus 로고
    • Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: Nucleophilic targets and adduct formation
    • LoPachin RM, Gavin T, Petersen DR, Barber DS (2009) Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: nucleophilic targets and adduct formation. Chem Res Toxicol 22, 1499-1508.
    • (2009) Chem Res Toxicol , vol.22 , pp. 1499-1508
    • Lopachin, R.M.1    Gavin, T.2    Petersen, D.R.3    Barber, D.S.4
  • 52
    • 0034939395 scopus 로고    scopus 로고
    • The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects
    • DOI 10.1007/s002130100815
    • Stough C, Lloyd J, Clarke J, Downey LA, Hutchison CW, Rodgers T, Nathan PJ (2001) The chronic effects of an extract ofBacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacol (Berl) 156, 481-484. (Pubitemid 32695859)
    • (2001) Psychopharmacology , vol.156 , Issue.4 , pp. 481-484
    • Stough, C.1    Lloyd, J.2    Clarke, J.3    Downey, L.A.4    Hutchison, C.W.5    Rodgers, T.6    Nathan, P.J.7
  • 53
    • 0036242416 scopus 로고    scopus 로고
    • The acute effects ofcombined administration ofGinkgo biloba and Bacopa monniera on cognitive function in humans
    • Maher BF, Stough C, Shelmerdine A, Wesnes K, Nathan PJ (2002) The acute effects ofcombined administration ofGinkgo biloba and Bacopa monniera on cognitive function in humans. Hum Psychopharmacol 17, 163-164.
    • (2002) Hum Psychopharmacol , vol.17 , pp. 163-164
    • Maher, B.F.1    Stough, C.2    Shelmerdine, A.3    Wesnes, K.4    Nathan, P.J.5
  • 55
    • 62149137729 scopus 로고    scopus 로고
    • Bacopa monniera leaf extract ameliorates hypo-baric hypoxia induced spatial memory impairment
    • Hota SK, Barhwal K, Baitharu I, Prasad D, Singh SB, Ilavazha-gan G (2009) Bacopa monniera leaf extract ameliorates hypo-baric hypoxia induced spatial memory impairment. Neurobiol Dis 34, 23-39.
    • (2009) Neurobiol Dis , vol.34 , pp. 23-39
    • Hota, S.K.1    Barhwal, K.2    Baitharu, I.3    Prasad, D.4    Singh, S.B.5    Ilavazha-Gan, G.6
  • 57
    • 16444379174 scopus 로고    scopus 로고
    • Gamma-glutamylcysteine ethyl ester-induced up-regulation of glutathione protects neurons against Abeta(1-42)-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease
    • Boyd-Kimball D, Sultana R, Abdul HM, Butterfield DA (2005) Gamma-glutamylcysteine ethyl ester-induced up-regulation of glutathione protects neurons against Abeta(1-42)-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. J Neurosci Res 79, 700-706.
    • (2005) J Neurosci Res , vol.79 , pp. 700-706
    • Boyd-Kimball, D.1    Sultana, R.2    Abdul, H.M.3    Butterfield, D.A.4
  • 60
    • 12444332057 scopus 로고    scopus 로고
    • Quantitative determination of the major saponin mixture bacoside A in Bacopa monnieri by HPLC
    • Deepak M, Sangli GK, Arun PC, Amit A (2005) Quantitative determination of the major saponin mixture bacoside A in Bacopa monnieri by HPLC. Phytochem Anal 16, 24-29.
    • (2005) Phytochem Anal , vol.16 , pp. 24-29
    • Deepak, M.1    Sangli, G.K.2    Arun, P.C.3    Amit, A.4
  • 61
    • 24644490031 scopus 로고    scopus 로고
    • Acrolein-induced cell death in PC12 cells: Role of mitochondria-mediated oxidative stress
    • Luo J, Robinson JP, Shi R (2005) Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress. Neurochem Int 47, 449-457.
    • (2005) Neurochem Int , vol.47 , pp. 449-457
    • Luo, J.1    Robinson, J.P.2    Shi, R.3
  • 62
    • 1342306400 scopus 로고    scopus 로고
    • Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease
    • Pocernich CB, Butterfield DA (2003) Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease. Neurotox Res 5, 515-520.
    • (2003) Neurotox Res , vol.5 , pp. 515-520
    • Pocernich, C.B.1    Butterfield, D.A.2
  • 63
    • 0035968183 scopus 로고    scopus 로고
    • Modulation of mito-chondrial function by hydrogen peroxide
    • Nulton-Persson AC, Szweda LI (2001) Modulation of mito-chondrial function by hydrogen peroxide. J Biol Chem 276, 23357-23361.
    • (2001) J Biol Chem , vol.276 , pp. 23357-23361
    • Nulton-Persson, A.C.1    Szweda, L.I.2
  • 64
    • 0036272650 scopus 로고    scopus 로고
    • β-Amyloid inhibits integrated mitochondrial respiration and key enzyme activities
    • Casley CS, Canevari L, Land JM, Clark JB, Sharpe MA (2002) β-Amyloid inhibits integrated mitochondrial respiration and key enzyme activities. J Neurochem 80, 91-100.
    • (2002) J Neurochem , vol.80 , pp. 91-100
    • Casley, C.S.1    Canevari, L.2    Land, J.M.3    Clark, J.B.4    Ma, S.5
  • 65
  • 66
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signalling
    • Hayden MS, Ghosh S (2008) Shared principles in NF-kappaB signalling. Cell 132, 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 67
    • 33845220134 scopus 로고    scopus 로고
    • Protection by EGb 761 against ft-amyloid-induced neurotoxicity: Involvement of NF-KB, SIRT1, and MAPKs pathways and inhibition of amyloid fibril formation
    • Longpre F, Garneau P, Christen Y, Ramassamy C (2006) Protection by EGb 761 against ft-amyloid-induced neurotoxicity: Involvement of NF-KB, SIRT1, and MAPKs pathways and inhibition of amyloid fibril formation. Free Radic Biol Med 41, 1781-1794.
    • (2006) Free Radic Biol Med , vol.41 , pp. 1781-1794
    • Longpre, F.1    Garneau, P.2    Christen, Y.3    Ramassamy, C.4
  • 68
    • 44349140124 scopus 로고    scopus 로고
    • NFkappaB-dependent control of BACE1 promoter transacti-vation by Abeta42
    • Buggia-Prevot V, Sevalle J, Rossner S, Checler F (2008) NFkappaB-dependent control of BACE1 promoter transacti-vation by Abeta42. J Biol Chem 283, 10037-10047.
    • (2008) J Biol Chem , vol.283 , pp. 10037-10047
    • Buggia-Prevot, V.1    Sevalle, J.2    Rossner, S.3    Checler, F.4
  • 69
    • 33645046630 scopus 로고    scopus 로고
    • Potential therapeutic targets in the NF-kappaB pathway for Alzheimer's disease
    • Collister KA, Albensi BC (2005) Potential therapeutic targets in the NF-kappaB pathway for Alzheimer's disease. Drug News Perspect 18, 623-629.
    • (2005) Drug News Perspect , vol.18 , pp. 623-629
    • Collister, K.A.1    Albensi, B.C.2
  • 70
    • 33947373035 scopus 로고    scopus 로고
    • P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells
    • Tanel A, Averill-Bates DA (2007) P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells. Cell Signal 19, 968-977.
    • (2007) Cell Signal , vol.19 , pp. 968-977
    • Tanel, A.1    Averill-Bates, D.A.2
  • 71
    • 2942589223 scopus 로고    scopus 로고
    • Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain
    • Swatton JE, Sellers LA, Faull RL, Holland A, Iritani S, and Bahn S (2004) Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain. Eur J Neurosci 19, 2711-2719.
    • (2004) Eur J Neurosci , vol.19 , pp. 2711-2719
    • Swatton, J.E.1    Sellers, L.A.2    Faull, R.L.3    Holland, A.4    Iritani, S.5    Bahn, S.6
  • 72
  • 73
    • 19444377638 scopus 로고    scopus 로고
    • Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway
    • Jang JH, Surh YJ (2005) Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway. Free Radic Biol Med 38, 1604-1613.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1604-1613
    • Jang, J.H.1    Surh, Y.J.2
  • 74
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW (2004) Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EM-BO J 23, 2369-2380.
    • (2004) EM-BO J , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 81
    • 23044441390 scopus 로고    scopus 로고
    • ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: Implication of p27kip1 in cell response to oxidative stress
    • Hu Y, Wang X, Zeng L, Cai DY, Sabapathy K, Goff SP, Fir-po EJ, Li B (2005) ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress. Mol Biol Cell 16, 3705-3718.
    • (2005) Mol Biol Cell , vol.16 , pp. 3705-3718
    • Hu, Y.1    Wang, X.2    Zeng, L.3    Cai, D.Y.4    Sabapathy, K.5    Goff, S.P.6    Fir-Po, E.J.7    Li, B.8
  • 82
    • 23844529468 scopus 로고    scopus 로고
    • Celas-trol protects against MPTP-and 3-nitropropionic acid-induced neurotoxicity
    • Cleren C, Calingasan NY, Chen J, Beal MF (2005) Celas-trol protects against MPTP-and 3-nitropropionic acid-induced neurotoxicity. J Neurochem 94, 95-1004.
    • (2005) J Neurochem , vol.94 , pp. 95-1004
    • Cleren, C.1    Calingasan, N.Y.2    Chen, J.3    Beal, M.F.4
  • 83
    • 38049121045 scopus 로고    scopus 로고
    • Celastrol inhibits production of nitric oxide and proinflammatory cy-tokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cells
    • Jung HW, Chung YS, Kim YS, Park YK (2007) Celastrol inhibits production of nitric oxide and proinflammatory cy-tokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cells. Exp Mol Med 39, 715-721.
    • (2007) Exp Mol Med , vol.39 , pp. 715-721
    • Jung, H.W.1    Chung, Y.S.2    Kim, Y.S.3    Park, Y.K.4
  • 84
    • 34347370406 scopus 로고    scopus 로고
    • Ginkgo biloba extract (EGb761) in Alzheimer's disease: Is there any evidence?
    • Ramassamy C, Longpre F, Christen Y (2007) Ginkgo biloba extract (EGb761) in Alzheimer's disease: is there any evidence? Curr Alzheimer Res 4, 253-262.
    • (2007) Curr Alzheimer Res , vol.4 , pp. 253-262
    • Ramassamy, C.1    Longpre, F.2    Christen, Y.3
  • 85
    • 0034121829 scopus 로고    scopus 로고
    • The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid
    • Bastianetto S, Ramassamy C, Dore S, Christen Y, Poirier J, Quirion R (2000) The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid. Eur J Neurosci 12, 1882-1890.
    • (2000) Eur J Neurosci , vol.12 , pp. 1882-1890
    • Bastianetto, S.1    Ramassamy, C.2    Dore, S.3    Christen, Y.4    Poirier, J.5    Quirion, R.6


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