메뉴 건너뛰기




Volumn 45, Issue 11, 2008, Pages 1510-1519

Protective effect of Pycnogenol in human neuroblastoma SH-SY5Y cells following acrolein-induced cytotoxicity

Author keywords

Acrolein; Glutathione; Neurodegeneration; Neuroprotection.; Oxidative stress; Pycnogenol

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; ACROLEIN; CARBONYL DERIVATIVE; FREE RADICAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; PYCNOGENOL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

EID: 56049093212     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.08.025     Document Type: Article
Times cited : (58)

References (60)
  • 1
    • 0035853707 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress
    • Kondo M., Oya-Ito T., Kumagai T., Osawa T., and Uchida K. Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress. J. Biol. Chem. 276 (2001) 12076-12083
    • (2001) J. Biol. Chem. , vol.276 , pp. 12076-12083
    • Kondo, M.1    Oya-Ito, T.2    Kumagai, T.3    Osawa, T.4    Uchida, K.5
  • 2
    • 24644443158 scopus 로고    scopus 로고
    • Oxidative stress in mitochondria: decision to survival and death of neurons in neurodegenerative disorders
    • Naoi M., Maruyama W., Shamoto-Nagai M., Yi H., Akao Y., and Tanaka M. Oxidative stress in mitochondria: decision to survival and death of neurons in neurodegenerative disorders. Mol. Neurobiol. 31 (2005) 81-93
    • (2005) Mol. Neurobiol. , vol.31 , pp. 81-93
    • Naoi, M.1    Maruyama, W.2    Shamoto-Nagai, M.3    Yi, H.4    Akao, Y.5    Tanaka, M.6
  • 4
    • 33750323814 scopus 로고    scopus 로고
    • In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: relevance to Alzheimer's disease and other oxidative stress-related neurodegenerative disorders
    • Ansari M.A., Joshi G., Huang Q., Opii W.O., Abdul H.M., Sultana R., and Butterfield D.A. In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: relevance to Alzheimer's disease and other oxidative stress-related neurodegenerative disorders. Free Radic. Biol. Med. 41 (2006) 1694-1703
    • (2006) Free Radic. Biol. Med. , vol.41 , pp. 1694-1703
    • Ansari, M.A.1    Joshi, G.2    Huang, Q.3    Opii, W.O.4    Abdul, H.M.5    Sultana, R.6    Butterfield, D.A.7
  • 5
    • 0042160300 scopus 로고    scopus 로고
    • The rotenone model of Parkinson's disease: genes, environment and mitochondria
    • Greenamyre J.T., Betarbet R., and Sherer T.B. The rotenone model of Parkinson's disease: genes, environment and mitochondria. Parkinsonism Relat. Disord. 9 Suppl 2 (2003) S59-64
    • (2003) Parkinsonism Relat. Disord. , vol.9 , Issue.SUPPL. 2
    • Greenamyre, J.T.1    Betarbet, R.2    Sherer, T.B.3
  • 6
    • 0032823769 scopus 로고    scopus 로고
    • Antioxidant defence mechanisms: from the beginning to the end (of the beginning)
    • Halliwell B. Antioxidant defence mechanisms: from the beginning to the end (of the beginning). Free Radic. Res. 31 (1999) 261-272
    • (1999) Free Radic. Res. , vol.31 , pp. 261-272
    • Halliwell, B.1
  • 7
    • 0028152717 scopus 로고
    • Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
    • Mecocci P., MacGarvey U., and Beal M.F. Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol. 36 (1994) 747-751
    • (1994) Ann. Neurol. , vol.36 , pp. 747-751
    • Mecocci, P.1    MacGarvey, U.2    Beal, M.F.3
  • 9
    • 0032799823 scopus 로고    scopus 로고
    • Vitamin E as an antioxidant/free radical scavenger against amyloid beta-peptide-induced oxidative stress in neocortical synaptosomal membranes and hippocampal neurons in culture: insights into Alzheimer's disease
    • Butterfield D.A., Koppal T., Subramaniam R., and Yatin S. Vitamin E as an antioxidant/free radical scavenger against amyloid beta-peptide-induced oxidative stress in neocortical synaptosomal membranes and hippocampal neurons in culture: insights into Alzheimer's disease. Rev. Neurosci. 10 (1999) 141-149
    • (1999) Rev. Neurosci. , vol.10 , pp. 141-149
    • Butterfield, D.A.1    Koppal, T.2    Subramaniam, R.3    Yatin, S.4
  • 10
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: evidence supporting it
    • Fahn S., and Cohen G. The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann. Neurol. 32 (1992) 804-812
    • (1992) Ann. Neurol. , vol.32 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 11
    • 0037099243 scopus 로고    scopus 로고
    • Pycnogenol protects neurons from amyloid-beta peptide-induced apoptosis
    • Peng Q.L., Buz'Zard A.R., and Lau B.H. Pycnogenol protects neurons from amyloid-beta peptide-induced apoptosis. Brain Res. 104 (2002) 55-65
    • (2002) Brain Res. , vol.104 , pp. 55-65
    • Peng, Q.L.1    Buz'Zard, A.R.2    Lau, B.H.3
  • 12
    • 0029967376 scopus 로고    scopus 로고
    • Preventive effect of natural and synthetic antioxidants on lipid peroxidation in the mammalian eye
    • Ueda T., Ueda T., and Armstrong D. Preventive effect of natural and synthetic antioxidants on lipid peroxidation in the mammalian eye. Ophthalmic Res. 28 (1996) 184-192
    • (1996) Ophthalmic Res. , vol.28 , pp. 184-192
    • Ueda, T.1    Ueda, T.2    Armstrong, D.3
  • 14
    • 20144386944 scopus 로고    scopus 로고
    • Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences
    • Ahmad M., Saleem S., Ahmad A.S., Yousuf S., Ansari M.A., Khan M.B., Ishrat T., Chaturvedi R.K., Agrawal A.K., and Islam F. Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences. J. Neurochem. 93 (2005) 94-104
    • (2005) J. Neurochem. , vol.93 , pp. 94-104
    • Ahmad, M.1    Saleem, S.2    Ahmad, A.S.3    Yousuf, S.4    Ansari, M.A.5    Khan, M.B.6    Ishrat, T.7    Chaturvedi, R.K.8    Agrawal, A.K.9    Islam, F.10
  • 15
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • Markesbery W.R. Oxidative stress hypothesis in Alzheimer's disease. Free Radic. Biol. Med. 23 (1997) 134-147
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 134-147
    • Markesbery, W.R.1
  • 16
    • 13844271390 scopus 로고    scopus 로고
    • Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures
    • Mercer L.D., Kelly B.L., Horne M.K., and Beart P.M. Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures. Biochem. Pharmacol. 69 (2005) 339-345
    • (2005) Biochem. Pharmacol. , vol.69 , pp. 339-345
    • Mercer, L.D.1    Kelly, B.L.2    Horne, M.K.3    Beart, P.M.4
  • 18
    • 0035868503 scopus 로고    scopus 로고
    • A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects
    • Youdim K.A., and Joseph J.A. A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects. Free Radic. Biol. Med. 30 (2001) 583-594
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 583-594
    • Youdim, K.A.1    Joseph, J.A.2
  • 20
    • 0018854928 scopus 로고
    • A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds
    • Brown J.P. A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds. Mutat. Res. 75 (1980) 243-277
    • (1980) Mutat. Res. , vol.75 , pp. 243-277
    • Brown, J.P.1
  • 21
    • 0033955308 scopus 로고    scopus 로고
    • Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity
    • Kobayashi M.S., Han D., and Packer L. Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity. Free Radic. Res. 32 (2000) 115-124
    • (2000) Free Radic. Res. , vol.32 , pp. 115-124
    • Kobayashi, M.S.1    Han, D.2    Packer, L.3
  • 22
    • 0031769670 scopus 로고    scopus 로고
    • Assay of inducible form of nitric oxide synthase activity: effect of flavonoids and plant extracts
    • Kobuchi H., Virgili F., and Packer L. Assay of inducible form of nitric oxide synthase activity: effect of flavonoids and plant extracts. Methods Enzymol. 301 (1999) 504-513
    • (1999) Methods Enzymol. , vol.301 , pp. 504-513
    • Kobuchi, H.1    Virgili, F.2    Packer, L.3
  • 23
    • 0034611648 scopus 로고    scopus 로고
    • In vitro inhibition of the activity of phosphorylase kinase, protein kinase C and protein kinase A by caffeic acid and a procyanidin-rich pine bark (Pinus marittima) extract
    • Nardini M., Scaccini C., Packer L., and Virgili F. In vitro inhibition of the activity of phosphorylase kinase, protein kinase C and protein kinase A by caffeic acid and a procyanidin-rich pine bark (Pinus marittima) extract. Biochim. Biophys. Acta 1474 (2000) 219-225
    • (2000) Biochim. Biophys. Acta , vol.1474 , pp. 219-225
    • Nardini, M.1    Scaccini, C.2    Packer, L.3    Virgili, F.4
  • 24
    • 0032839592 scopus 로고    scopus 로고
    • Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol
    • Packer L., Rimbach G., and Virgili F. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol. Free Radic. Biol. Med. 27 (1999) 704-724
    • (1999) Free Radic. Biol. Med. , vol.27 , pp. 704-724
    • Packer, L.1    Rimbach, G.2    Virgili, F.3
  • 26
    • 2442604136 scopus 로고    scopus 로고
    • Pycnogenol and vitamin E inhibit ethanol-induced apoptosis in rat cerebellar granule cells
    • Siler-Marsiglio K.I., Shaw G., and Heaton M.B. Pycnogenol and vitamin E inhibit ethanol-induced apoptosis in rat cerebellar granule cells. J. Neurobiol. 59 (2004) 261-271
    • (2004) J. Neurobiol. , vol.59 , pp. 261-271
    • Siler-Marsiglio, K.I.1    Shaw, G.2    Heaton, M.B.3
  • 28
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H., Schaur R.J., and Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11 (1991) 81-128
    • (1991) Free Radic. Biol. Med. , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 29
    • 0034667741 scopus 로고    scopus 로고
    • Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures
    • Lovell M.A., Xie C., and Markesbery W.R. Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures. Free Radic. Biol. Med. 29 (2000) 714-720
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 714-720
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 31
    • 0033864802 scopus 로고    scopus 로고
    • The molecular effects of acrolein
    • Kehrer J.P., and Biswal S.S. The molecular effects of acrolein. Toxicol Sci 57 (2000) 6-15
    • (2000) Toxicol Sci , vol.57 , pp. 6-15
    • Kehrer, J.P.1    Biswal, S.S.2
  • 32
    • 1342306400 scopus 로고    scopus 로고
    • Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease
    • Pocernich C.B., and Butterfield D.A. Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease. Neurotox. Res. 5 (2003) 515-520
    • (2003) Neurotox. Res. , vol.5 , pp. 515-520
    • Pocernich, C.B.1    Butterfield, D.A.2
  • 33
    • 0035112495 scopus 로고    scopus 로고
    • Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
    • Lovell M.A., Xie C., and Markesbery W.R. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol. Aging 22 (2001) 187-194
    • (2001) Neurobiol. Aging , vol.22 , pp. 187-194
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 34
    • 0034988283 scopus 로고    scopus 로고
    • Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease
    • Pocernich C.B., Cardin A.L., Racine C.L., Lauderback C.M., and Butterfield D.A. Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease. Neurochem. Int. 39 (2001) 141-149
    • (2001) Neurochem. Int. , vol.39 , pp. 141-149
    • Pocernich, C.B.1    Cardin, A.L.2    Racine, C.L.3    Lauderback, C.M.4    Butterfield, D.A.5
  • 35
    • 35148895156 scopus 로고    scopus 로고
    • Anti-apoptotic effect of esculin on dopamine-induced cytotoxicity in the human neuroblastoma SH-SY5Y cell line
    • Zhao D.L., Zou L.B., Lin S., Shi J.G., and Zhu H.B. Anti-apoptotic effect of esculin on dopamine-induced cytotoxicity in the human neuroblastoma SH-SY5Y cell line. Neuropharmacology 53 (2007) 724-732
    • (2007) Neuropharmacology , vol.53 , pp. 724-732
    • Zhao, D.L.1    Zou, L.B.2    Lin, S.3    Shi, J.G.4    Zhu, H.B.5
  • 36
    • 0037168998 scopus 로고    scopus 로고
    • Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid
    • Nardini M., Finkelstein E.I., Reddy S., Valacchi G., Traber M., Cross C.E., and van der Vliet A. Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid. Toxicology 170 (2002) 173-185
    • (2002) Toxicology , vol.170 , pp. 173-185
    • Nardini, M.1    Finkelstein, E.I.2    Reddy, S.3    Valacchi, G.4    Traber, M.5    Cross, C.E.6    van der Vliet, A.7
  • 38
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
    • Rajagopalan S., Kurz S., Munzel T., Tarpey M., Freeman B.A., Griendling K.K., and Harrison D.G. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J. Clin. Invest. 97 (1996) 1916-1923
    • (1996) J. Clin. Invest. , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3    Tarpey, M.4    Freeman, B.A.5    Griendling, K.K.6    Harrison, D.G.7
  • 39
    • 0032983334 scopus 로고    scopus 로고
    • beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease
    • Bianca V.D., Dusi S., Bianchini E., Dal Pra I., and Rossi F. beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease. J. Biol. Chem. 274 (1999) 15493-15499
    • (1999) J. Biol. Chem. , vol.274 , pp. 15493-15499
    • Bianca, V.D.1    Dusi, S.2    Bianchini, E.3    Dal Pra, I.4    Rossi, F.5
  • 40
    • 24644490031 scopus 로고    scopus 로고
    • Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress
    • Luo J., Robinson J.P., and Shi R. Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress. Neurochem. Int. 47 (2005) 449-457
    • (2005) Neurochem. Int. , vol.47 , pp. 449-457
    • Luo, J.1    Robinson, J.P.2    Shi, R.3
  • 41
    • 12744277558 scopus 로고    scopus 로고
    • Acrolein induces oxidative stress in brain mitochondria
    • Luo J., and Shi R. Acrolein induces oxidative stress in brain mitochondria. Neurochem. Int. 46 (2005) 243-252
    • (2005) Neurochem. Int. , vol.46 , pp. 243-252
    • Luo, J.1    Shi, R.2
  • 42
    • 0032948006 scopus 로고    scopus 로고
    • Peroxynitrite-induced alterations in synaptosomal membrane proteins: insight into oxidative stress in Alzheimer's disease
    • Koppal T., Drake J., Yatin S., Jordan B., Varadarajan S., Bettenhausen L., and Butterfield D.A. Peroxynitrite-induced alterations in synaptosomal membrane proteins: insight into oxidative stress in Alzheimer's disease. J. Neurochem. 72 (1999) 310-317
    • (1999) J. Neurochem. , vol.72 , pp. 310-317
    • Koppal, T.1    Drake, J.2    Yatin, S.3    Jordan, B.4    Varadarajan, S.5    Bettenhausen, L.6    Butterfield, D.A.7
  • 44
    • 0033967073 scopus 로고    scopus 로고
    • New drugs for the treatment of Parkinson's disease
    • LeWitt P.A. New drugs for the treatment of Parkinson's disease. Pharmacotherapy 20 (2000) 26S-32S
    • (2000) Pharmacotherapy , vol.20
    • LeWitt, P.A.1
  • 46
    • 0036961980 scopus 로고    scopus 로고
    • Selenium-induced alteration of lipids, lipid peroxidation, and thiol group in circadian rhythm centers of rat
    • Islam F., Zia S., Sayeed I., Zafar K.S., and Ahmad A.S. Selenium-induced alteration of lipids, lipid peroxidation, and thiol group in circadian rhythm centers of rat. Biol. Trace Elem. Res. 90 (2002) 203-214
    • (2002) Biol. Trace Elem. Res. , vol.90 , pp. 203-214
    • Islam, F.1    Zia, S.2    Sayeed, I.3    Zafar, K.S.4    Ahmad, A.S.5
  • 47
    • 0032435767 scopus 로고    scopus 로고
    • Glutathione therapy: from prodrugs to genes
    • Anderson M.E., and Luo J.L. Glutathione therapy: from prodrugs to genes. Semin. Liver Dis. 18 (1998) 415-424
    • (1998) Semin. Liver Dis. , vol.18 , pp. 415-424
    • Anderson, M.E.1    Luo, J.L.2
  • 48
    • 0037097270 scopus 로고    scopus 로고
    • Elevation of brain glutathione by gamma-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress
    • Drake J., Kanski J., Varadarajan S., Tsoras M., and Butterfield D.A. Elevation of brain glutathione by gamma-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress. J. Neurosci. Res. 68 (2002) 776-784
    • (2002) J. Neurosci. Res. , vol.68 , pp. 776-784
    • Drake, J.1    Kanski, J.2    Varadarajan, S.3    Tsoras, M.4    Butterfield, D.A.5
  • 49
    • 0033967664 scopus 로고    scopus 로고
    • In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain
    • Pocernich C.B., La Fontaine M., and Butterfield D.A. In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain. Neurochem. Int. 36 (2000) 185-191
    • (2000) Neurochem. Int. , vol.36 , pp. 185-191
    • Pocernich, C.B.1    La Fontaine, M.2    Butterfield, D.A.3
  • 50
    • 0342264396 scopus 로고    scopus 로고
    • Urinary metabolites of French maritime pine bark extract in humans
    • Duweler K.G., and Rohdewald P. Urinary metabolites of French maritime pine bark extract in humans. Die Pharm. 55 (2000) 364-368
    • (2000) Die Pharm. , vol.55 , pp. 364-368
    • Duweler, K.G.1    Rohdewald, P.2
  • 51
  • 52
    • 0032568935 scopus 로고    scopus 로고
    • Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins
    • Uchida K., Kanematsu M., Morimitsu Y., Osawa T., Noguchi N., and Niki E. Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins. J. Biol. Chem. 273 (1998) 16058-16066
    • (1998) J. Biol. Chem. , vol.273 , pp. 16058-16066
    • Uchida, K.1    Kanematsu, M.2    Morimitsu, Y.3    Osawa, T.4    Noguchi, N.5    Niki, E.6
  • 54
    • 0842267115 scopus 로고    scopus 로고
    • Acrolein induces axolemmal disruption, oxidative stress, and mitochondrial impairment in spinal cord tissue
    • Luo J., and Shi R. Acrolein induces axolemmal disruption, oxidative stress, and mitochondrial impairment in spinal cord tissue. Neurochem. Int. 44 (2004) 475-486
    • (2004) Neurochem. Int. , vol.44 , pp. 475-486
    • Luo, J.1    Shi, R.2
  • 56
    • 0037298498 scopus 로고    scopus 로고
    • Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity
    • Cao Z., Hardej D., Trombetta L.D., Trush M.A., and Li Y. Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity. Atherosclerosis 166 (2003) 291-301
    • (2003) Atherosclerosis , vol.166 , pp. 291-301
    • Cao, Z.1    Hardej, D.2    Trombetta, L.D.3    Trush, M.A.4    Li, Y.5
  • 57
    • 0037008669 scopus 로고    scopus 로고
    • Thiolation of protein-bound carcinogenic aldehyde. An electrophilic acrolein-lysine adduct that covalently binds to thiols
    • Furuhata A., Nakamura M., Osawa T., and Uchida K. Thiolation of protein-bound carcinogenic aldehyde. An electrophilic acrolein-lysine adduct that covalently binds to thiols. J. Biol. Chem. 277 (2002) 27919-27926
    • (2002) J. Biol. Chem. , vol.277 , pp. 27919-27926
    • Furuhata, A.1    Nakamura, M.2    Osawa, T.3    Uchida, K.4
  • 58
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide
    • Mark R.J., Lovell M.A., Markesbery W.R., Uchida K., and Mattson M.P. A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. J. Neurochem. 68 (1997) 255-264
    • (1997) J. Neurochem. , vol.68 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 59
    • 0242330832 scopus 로고    scopus 로고
    • Ethanol-induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons
    • Ramachandran V., Watts L.T., Maffi S.K., Chen J., Schenker S., and Henderson G. Ethanol-induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons. J. Neurosci. Res. 74 (2003) 577-588
    • (2003) J. Neurosci. Res. , vol.74 , pp. 577-588
    • Ramachandran, V.1    Watts, L.T.2    Maffi, S.K.3    Chen, J.4    Schenker, S.5    Henderson, G.6
  • 60
    • 0033866163 scopus 로고    scopus 로고
    • Deuterium isotope effects and product studies for the oxidation of N(omega)-allyl-L-arginine and N(omega)-allyl-N(omega)-hydroxy-L-arginine by neuronal nitric oxide synthase
    • Hah J.M., Roman L.J., and Silverman R.B. Deuterium isotope effects and product studies for the oxidation of N(omega)-allyl-L-arginine and N(omega)-allyl-N(omega)-hydroxy-L-arginine by neuronal nitric oxide synthase. Bioorg. Med. Chem. 8 (2000) 1931-1936
    • (2000) Bioorg. Med. Chem. , vol.8 , pp. 1931-1936
    • Hah, J.M.1    Roman, L.J.2    Silverman, R.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.