Detection and quantification of endogenous cyclic DNA adducts derived from trans-4-hydroxy-2-nonenal in human brain tissue by isotope dilution capillary liquid chromatography nanoelectrospray tandem mass spectrometry

Chemical Research in Toxicology

Volumn 19, Issue 5, 2006, Pages 710-718

  Liu, Xinli ^a   Lovell, Mark A ^a,b   Lynn, Bert C ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; CARBON 13; CIRCULAR DNA; NITROGEN 15; NUCLEOSIDE; NUCLEOTIDE; PHOSPHORUS 32;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; AUTOPSY; BRAIN TISSUE; CAPILLARY CHROMATOGRAPHY; CATTLE; CONTROLLED STUDY; DNA ADDUCT; ELECTROSPRAY MASS SPECTROMETRY; ENZYME DEGRADATION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; ION TRAP MASS SPECTROMETRY; ISOTOPE DILUTION ASSAY; ISOTOPE LABELING; NONHUMAN; PARIETAL LOBE; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; STANDARD; SUBICULUM; SYNTHESIS;

AGED; AGED, 80 AND OVER; ALDEHYDES; ALZHEIMER DISEASE; BRAIN; CHROMATOGRAPHY, LIQUID; DEOXYGUANOSINE; DNA; DNA ADDUCTS; FEMALE; HUMANS; MALE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33744460225     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0502903     Document Type: Article

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