-
1
-
-
0031128778
-
A model for susceptibility polymorphisms for complex diseases: Apolipoprotein E and Alzheimer disease
-
1. Roses, A. D. 1997. A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease. Neurogenetics 1: 3-11.
-
(1997)
Neurogenetics
, vol.1
, pp. 3-11
-
-
Roses, A.D.1
-
2
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
2. Strittmatter, W. J., A. M. Saunders, D. Schmeche, V. M. Pericak, J. Enghild, G. S. Salvesen & A. D. Roses. 1993. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. USA 90: 1977-1981.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmeche, D.3
Pericak, V.M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
3
-
-
0027327267
-
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
3. Saunders, A. M., W. J. Strittmatter, D. Schmechel, P. H. St. George-Hyslop, M. A. Pericak-Vance, S. H. Joo, B. L. Rosi, J. F. Gusella, D. R. McLaughlin-Crapper, M. J. Alberts, C. Hulette, B. Crain, D. Goldgaber & A. D. Roses. 1993. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43: 1467-1472.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
St. George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
McLaughlin-Crapper, D.R.9
Alberts, M.J.10
Hulette, C.11
Crain, B.12
Goldgaber, D.13
Roses, A.D.14
-
4
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
4. Mahley, R. W. 1988. Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology. Science 240: 622-630.
-
(1988)
Science
, vol.240
, pp. 622-630
-
-
Mahley, R.W.1
-
5
-
-
0030005627
-
Apolipoprotein E alleles as risk factors in Alzheimer disease
-
5. Roses, A. D. 1996. Apolipoprotein E alleles as risk factors in Alzheimer disease. Annu. Rev. Med. 47: 387-400.
-
(1996)
Annu. Rev. Med.
, vol.47
, pp. 387-400
-
-
Roses, A.D.1
-
6
-
-
0000855672
-
Measuring the genetic contribution of APOE in late-onset Alzheimer diease
-
6. Roses, A. D., B. Devlin, P. M. Conneally, G. W. Small, A. M. Saunders, M. Pritchard, P. A. Locke, J. L. Haines, M. A. Pericak-Vance & N. Risch. 1995. Measuring the genetic contribution of APOE in late-onset Alzheimer diease. Amer. J. Hum. Genet. 57: A202.
-
(1995)
Amer. J. Hum. Genet.
, vol.57
-
-
Roses, A.D.1
Devlin, B.2
Conneally, P.M.3
Small, G.W.4
Saunders, A.M.5
Pritchard, M.6
Locke, P.A.7
Haines, J.L.8
Pericak-Vance, M.A.9
Risch, N.10
-
7
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
7. Corder, E. H., A. M. Saunders, W. J. Strittmatter, D. E. Schmechel, P. C. Gaskell, G. W. Small, A. D. Roses, J. L. Haines & M. A. Pericak-Vance. 1993. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261: 921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
8
-
-
0028305380
-
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
-
8. Corder, E. H., A. M. Saunders, N. J. Risch, W. J. Strittmatter, D. E. Schmechel, P. J. Gaskell, J. B. Rimmler, P. A. Locke, P. M. Conneally, K. E. Schmader, G. W. Small, A. D. Roses, J. L. Haines & M. A. Pericak-Vance. 1994. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat. Genet. 7: 180-184.
-
(1994)
Nat. Genet.
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
Strittmatter, W.J.4
Schmechel, D.E.5
Gaskell, P.J.6
Rimmler, J.B.7
Locke, P.A.8
Conneally, P.M.9
Schmader, K.E.10
Small, G.W.11
Roses, A.D.12
Haines, J.L.13
Pericak-Vance, M.A.14
-
9
-
-
0027936838
-
Apolipoprotein E affects the rate of Alzheimer disease expression: Beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease
-
9. Roses, A. D. 1994. Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease. J. Neuropathol. Exp. Neurol. 53: 429-437.
-
(1994)
J. Neuropathol. Exp. Neurol.
, vol.53
, pp. 429-437
-
-
Roses, A.D.1
-
11
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
-
11. McKhann, G., D. Drachman, M. Folstein, R. Katzman, D. Price & E. M. Stadlan. 1984. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.D.1
Drachman, M.2
Folstein, R.3
Price, D.4
Stadlan, E.M.5
-
12
-
-
0030055982
-
APOE genotyping in differential diagnosis of Alzheimer's disease
-
12. Slooter, A. J., M. M. B. Breteler, A. Ott, C. Van Broeckhoven & C. M. Van Duijn. 1996. APOE genotyping in differential diagnosis of Alzheimer's disease. Lancet 348: 334.
-
(1996)
Lancet
, vol.348
, pp. 334
-
-
Slooter, A.J.1
Breteler, M.M.B.2
Ott, A.3
Van Broeckhoven, C.4
Van Duijn, C.M.5
-
13
-
-
0027411093
-
Making the diagnosis of Alzheimer's disease. A primer for practicing pathologists
-
13. Mirra, S. S., M. N. Hart & R. D. Terry. 1993. Making the diagnosis of Alzheimer's disease. A primer for practicing pathologists. Arch. Pathol. Lab. Med. 117: 132-144.
-
(1993)
Arch. Pathol. Lab. Med.
, vol.117
, pp. 132-144
-
-
Mirra, S.S.1
Hart, M.N.2
Terry, R.D.3
-
14
-
-
0025908356
-
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
-
14. Mirra, S. S., A. Heyman, D. McKeel, S. M. Sumi, B. J. Crain, L. M. Brownlee, F. S. Vogel, J. P. Hughes, G. Van Belle & L. Berg. 1991. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41: 479-486.
-
(1991)
Neurology
, vol.41
, pp. 479-486
-
-
Mirra, S.S.1
Heyman, A.2
McKeel, D.3
Sumi, S.M.4
Crain, B.J.5
Brownlee, L.M.6
Vogel, F.S.7
Hughes, J.P.8
Van Belle, G.9
Berg, L.10
-
15
-
-
15844393893
-
Specificity, sensitivity and predictive value of apolipoprotein E genotyping for sporadic Alzheimer disease
-
15. Saunders, A. M., C. Hulette, K. A. Welsh, D. E. Schmechel, B. Crain, J. R. Burke, M. J. Alberts, W. J. Strittmatter, J. C. S. Breitner, C. Rosenberg, S. V. Scott, P. C. J. Gaskell, M. A. Pericak-Vance & A. D. Roses. 1996. Specificity, sensitivity and predictive value of apolipoprotein E genotyping for sporadic Alzheimer disease. Lancet 348: 90-93.
-
(1996)
Lancet
, vol.348
, pp. 90-93
-
-
Saunders, A.M.1
Hulette, C.2
Welsh, K.A.3
Schmechel, D.E.4
Crain, B.5
Burke, J.R.6
Alberts, M.J.7
Strittmatter, W.J.8
Breitner, J.C.S.9
Rosenberg, C.10
Scott, S.V.11
Gaskell, P.C.J.12
Pericak-Vance, M.A.13
Roses, A.D.14
-
16
-
-
0029840452
-
Apolipoprotein-E genotyping in diagnosis of Alzheimer's disease
-
16. Smith, A. D., K. A. Jobst, C. Johnston, C. Joachim & Z. Nagy. 1996. Apolipoprotein-E genotyping in diagnosis of Alzheimer's disease. Lancet 348: 483-484.
-
(1996)
Lancet
, vol.348
, pp. 483-484
-
-
Smith, A.D.1
Jobst, K.A.2
Johnston, C.3
Joachim, C.4
Nagy, Z.5
-
17
-
-
0029840452
-
Apolipoprotein-E genotyping in the diagnosis of Alzheimer's disease in an autopsy confirmed series
-
17. Kakulas, B. A., S. D. Wilton, V. A. Fabian & T. M. Jones. 1996. Apolipoprotein-E genotyping in the diagnosis of Alzheimer's disease in an autopsy confirmed series. Lancet 348: 483.
-
(1996)
Lancet
, vol.348
, pp. 483
-
-
Kakulas, B.A.1
Wilton, S.D.2
Fabian, V.A.3
Jones, T.M.4
-
18
-
-
0030801138
-
Apolipoprotein E genotypes in a neuropathological series from the consortium to establish a registry for Alzheimer's disease
-
18. Welsh-Bohmer, K. A., M. Gearing, A. M. Saunders, A. D. Roses & S. Mirra. 1997. Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease. Ann. Neurol. 42: 319-325.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 319-325
-
-
Welsh-Bohmer, K.A.1
Gearing, M.2
Saunders, A.M.3
Roses, A.D.4
Mirra, S.5
-
19
-
-
0029058821
-
Perspective: On the metabolism of apolipoprotein E and the Alzheimer diseases
-
19. Roses, A. D. 1995. Perspective: On the metabolism of apolipoprotein E and the Alzheimer diseases. Exp. Neurol. 132: 149-156.
-
(1995)
Exp. Neurol.
, vol.132
, pp. 149-156
-
-
Roses, A.D.1
-
20
-
-
0025878638
-
Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation
-
20. Linton, M. F., R. Gish, S. T. Hubl, E. Butler, C. Esquivel, W. I. Bry, J. K. Boyles, M. R. Wardell & S. G. Young. 1991. Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation. J. Clin. Invest. 88: 270-281.
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 270-281
-
-
Linton, M.F.1
Gish, R.2
Hubl, S.T.3
Butler, E.4
Esquivel, C.5
Bry, W.I.6
Boyles, J.K.7
Wardell, M.R.8
Young, S.G.9
-
21
-
-
0028123071
-
Alzheimer's disease: A central role for amyloid
-
21. Selkoe, D. J. 1994. Alzheimer's disease: A central role for amyloid. J. Neuropathol. Exp. Neurol. 53: 438-447.
-
(1994)
J. Neuropathol. Exp. Neurol.
, vol.53
, pp. 438-447
-
-
Selkoe, D.J.1
-
22
-
-
0025971426
-
Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease
-
22. Namba, Y., M. Tomonaga, H. Kawasaki, E. Otomo & K. Ikeda. 1991. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res 541: 163-166.
-
(1991)
Brain Res
, vol.541
, pp. 163-166
-
-
Namba, Y.1
Tomonaga, M.2
Kawasaki, H.3
Otomo, E.4
Ikeda, K.5
-
23
-
-
0001776297
-
Pattern of apolipoprotein E immunoreactivity during brain aging
-
A. D. Roses, K. H. Weisgraber & Y. Christen, Eds. Springer-Verlag. Berlin
-
23. Schmechel, D. E., M. O. Tiller, P. Tong, M. McSwain, S-H. Han, R. Angel, D. S. Burkhart & M. K. Izard. 1996. Pattern of apolipoprotein E immunoreactivity during brain aging. In Apolipoprotein E and Alzheimer's Disease. A. D. Roses, K. H. Weisgraber & Y. Christen, Eds. : 29-48. Springer-Verlag. Berlin.
-
(1996)
Apolipoprotein E and Alzheimer's Disease
, pp. 29-48
-
-
Schmechel, D.E.1
Tiller, M.O.2
Tong, P.3
McSwain, M.4
Han, S.-H.5
Angel, R.6
Burkhart, D.S.7
Izard, M.K.8
-
24
-
-
0028018114
-
Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls
-
24. Han, S. H., C. Hulette, A. M. Saunders, G. Einstein, M. A. Pericak-Vance, W. J. Strittmatter, A. D. Roses & D. E. Schmechel. 1994. Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. Exp. Neurol. 128: 13-26.
-
(1994)
Exp. Neurol.
, vol.128
, pp. 13-26
-
-
Han, S.H.1
Hulette, C.2
Saunders, A.M.3
Einstein, G.4
Pericak-Vance, M.A.5
Strittmatter, W.J.6
Roses, A.D.7
Schmechel, D.E.8
-
25
-
-
0027994092
-
Apolipoprotein E is localized to the cytoplasm of human cortical neurons: A light and electron microscopic study
-
25. Han, S. H., G. Einstein, K. H. Weisgraber, W. J. Strittmatter, A. M. Saunders, M. A. Pericak-Vance, A. D. Roses & D. E. Schmechel. 1994. Apolipoprotein E is localized to the cytoplasm of human cortical neurons: A light and electron microscopic study. J. Neuropathol. Exp. Neurol. 53: 535-544.
-
(1994)
J. Neuropathol. Exp. Neurol.
, vol.53
, pp. 535-544
-
-
Han, S.H.1
Einstein, G.2
Weisgraber, K.H.3
Strittmatter, W.J.4
Saunders, A.M.5
Pericak-Vance, M.A.6
Roses, A.D.7
Schmechel, D.E.8
-
26
-
-
0029032732
-
Apolipoprotein E immunoreactivity within neurofibrillary tangles: Relationship to tau and PHF in Alzheimer's disease
-
26. Benzing, W. C. & E. J. Mufson. 1995. Apolipoprotein E immunoreactivity within neurofibrillary tangles: Relationship to tau and PHF in Alzheimer's disease. Exp. Neurol. 132: 162-171.
-
(1995)
Exp. Neurol.
, vol.132
, pp. 162-171
-
-
Benzing, W.C.1
Mufson, E.J.2
-
27
-
-
0030175279
-
Human apolipoprotein E2, E3 and E4 isoform-specific transgenic mice: Human-like pattern of neuronal immunoreactivity in central nervous system not observed in wild type mice
-
27. Xu, P-T, D. Schmechel, T. Rothrock-Christian, D. S. Burkhart, H-L. Qui, B. Popko, P. Sullivan, N. Maeda, A. M. Saunders, A. D. Roses & J. R. Gilbert. 1996. Human apolipoprotein E2, E3 and E4 isoform-specific transgenic mice: Human-like pattern of neuronal immunoreactivity in central nervous system not observed in wild type mice. Neurobiol. Dis. 3: 229-245.
-
(1996)
Neurobiol. Dis.
, vol.3
, pp. 229-245
-
-
Xu, P.-T.1
Schmechel, D.2
Rothrock-Christian, T.3
Burkhart, D.S.4
Qui, H.-L.5
Popko, B.6
Sullivan, P.7
Maeda, N.8
Saunders, A.M.9
Roses, A.D.10
Gilbert, J.R.11
-
28
-
-
0030741533
-
Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis
-
28. Sullivan, P. M., H. Mezdour, Y. Aratari, C. Krouff, J. Najib, R. L. Reddick, S. Quarfordt & N. Maeda. 1997. Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. J. Biol. Chem. 272(29): 17972-17980.
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.29
, pp. 17972-17980
-
-
Sullivan, P.M.1
Mezdour, H.2
Aratari, Y.3
Krouff, C.4
Najib, J.5
Reddick, R.L.6
Quarfordt, S.7
Maeda, N.8
-
29
-
-
0032562645
-
Regionally specific neuronal expression of human apoE gene in transgenic mice
-
29. Xu, P. T., J. R. Gilbert, H. L. Qui, T. Rothrockchristian, D. L. Settles, A. D. Roses & D. E. Schmechel. 1998. Regionally specific neuronal expression of human apoE gene in transgenic mice. Neurosci. Lett. 246(2): 65-68.
-
(1998)
Neurosci. Lett.
, vol.246
, Issue.2
, pp. 65-68
-
-
Xu, P.T.1
Gilbert, J.R.2
Qui, H.L.3
Rothrockchristian, T.4
Settles, D.L.5
Roses, A.D.6
Schmechel, D.E.7
-
30
-
-
0027471464
-
A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice
-
30. Simonet, W. S., N. Bucay, S. J. Lauer & J. M. Taylor. 1993. A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice. J. Biol. Chem. 268: 8221-8229.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8221-8229
-
-
Simonet, W.S.1
Bucay, N.2
Lauer, S.J.3
Taylor, J.M.4
-
31
-
-
0032545939
-
Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease
-
31. Mayeux, R., A. M. Saunders, S. Shea, S. Mirra, D. Evans, A. D. Roses, B. T. Crain, M. X. Tang & C. H. Phelps. 1998. Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. N. Engl. J. Med. 338(8): 506-511.
-
(1998)
N. Engl. J. Med.
, vol.338
, Issue.8
, pp. 506-511
-
-
Mayeux, R.1
Saunders, A.M.2
Shea, S.3
Mirra, S.4
Evans, D.5
Roses, A.D.6
Crain, B.T.7
Tang, M.X.8
Phelps, C.H.9
|