-
1
-
-
0037469076
-
Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease
-
Bennett DA, Wilson RS, Schneider JA, et al. Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease. Neurology 2003; 60:246-252.
-
(2003)
Neurology
, vol.60
, pp. 246-252
-
-
Bennett, D.A.1
Wilson, R.S.2
Schneider, J.A.3
-
2
-
-
0028841027
-
Apolipoprotein E, dementia, and cortical deposition of beta-amyloid protein
-
Polvikoski T, Sulkava R, Haltia M, et al. Apolipoprotein E, dementia, and cortical deposition of beta-amyloid protein. N Engl J Med 1995;333:1242-1247.
-
(1995)
N Engl J Med
, vol.333
, pp. 1242-1247
-
-
Polvikoski, T.1
Sulkava, R.2
Haltia, M.3
-
3
-
-
38349146483
-
E and Alzheimer's disease: Molecular mechanisms and therapeutic opportunities
-
Cedazo-Minguez A. Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities. J Cell Mol Med 2007;11:1227-1238.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 1227-1238
-
-
Apolipoprotein, C.-M.A.1
-
4
-
-
0032829336
-
Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are diseaserelated and apolipoprotein E genotype dependent
-
Beffert U, Cohn JS, Petit-Turcotte C, et al. Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are diseaserelated and apolipoprotein E genotype dependent. Brain Res 1999;843:87-94.
-
(1999)
Brain Res
, vol.843
, pp. 87-94
-
-
Beffert, U.1
Cohn, J.S.2
Petit-Turcotte, C.3
-
5
-
-
0030696944
-
-
Roses AD. Apolipoprotein E, a gene with complex biological interactions in the aging brain. Neurobiol Dis 1997;4: 170-185.
-
Roses AD. Apolipoprotein E, a gene with complex biological interactions in the aging brain. Neurobiol Dis 1997;4: 170-185.
-
-
-
-
6
-
-
0036130129
-
Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: Mechanistic implications for apoE4 enhanced amyloid burden and risk for Alzheimer's disease
-
Esler WP, Marshall JR, Stimson ER, et al. Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: mechanistic implications for apoE4 enhanced amyloid burden and risk for Alzheimer's disease. Amyloid 2002;9:1-12.
-
(2002)
Amyloid
, vol.9
, pp. 1-12
-
-
Esler, W.P.1
Marshall, J.R.2
Stimson, E.R.3
-
7
-
-
0031021296
-
Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele
-
Arendt T, Schindler C, Bruckner MK, et al. Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele. J Neurosci 1997;17:516-529.
-
(1997)
J Neurosci
, vol.17
, pp. 516-529
-
-
Arendt, T.1
Schindler, C.2
Bruckner, M.K.3
-
8
-
-
40849111266
-
Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions
-
Reiman EM, Chen K, Caselli RJ, et al. Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions. Neuroimage 2008;40: 1214-1221.
-
(2008)
Neuroimage
, vol.40
, pp. 1214-1221
-
-
Reiman, E.M.1
Chen, K.2
Caselli, R.J.3
-
9
-
-
44649190480
-
Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers
-
Burggren AC, Zeineh MM, Ekstrom AD, et al. Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers. Neuroimage 2008;41:1177-1183.
-
(2008)
Neuroimage
, vol.41
, pp. 1177-1183
-
-
Burggren, A.C.1
Zeineh, M.M.2
Ekstrom, A.D.3
-
10
-
-
34250801552
-
Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates
-
Chen K, Reiman EM, Alexander GE, et al. Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates. Am J Psychiatry 2007;164:916-921.
-
(2007)
Am J Psychiatry
, vol.164
, pp. 916-921
-
-
Chen, K.1
Reiman, E.M.2
Alexander, G.E.3
-
11
-
-
34248324435
-
Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: An observational study
-
Shaw P, Lerch JP, Pruessner JC, et al. Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study. Lancet Neurol 2007;6:494-500.
-
(2007)
Lancet Neurol
, vol.6
, pp. 494-500
-
-
Shaw, P.1
Lerch, J.P.2
Pruessner, J.C.3
-
12
-
-
33644697324
-
Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET
-
Drzezga A, Grimmer T, Riemenschneider M, et al. Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET. J Nucl Med 2005;46:1625-1632.
-
(2005)
J Nucl Med
, vol.46
, pp. 1625-1632
-
-
Drzezga, A.1
Grimmer, T.2
Riemenschneider, M.3
-
13
-
-
40449102563
-
Apolipoprotein E epsilon 4 allele is associated with increased atrophy in progressive mild cognitive impairment: A voxelbased morphometric study
-
Hamalainen A, Grau-Olivares M, Tervo S, et al. Apolipoprotein E epsilon 4 allele is associated with increased atrophy in progressive mild cognitive impairment: a voxelbased morphometric study. Neurodegen Dis 2008;5:186- 189.
-
(2008)
Neurodegen Dis
, vol.5
, pp. 186-189
-
-
Hamalainen, A.1
Grau-Olivares, M.2
Tervo, S.3
-
14
-
-
19944427952
-
Cerebral glucose metabolism in patients with AD and different APOE genotypes
-
Drzezga A, Riemenschneider M, Strassner B, et al. Cerebral glucose metabolism in patients with AD and different APOE genotypes. Neurology 2005;64:102-107.
-
(2005)
Neurology
, vol.64
, pp. 102-107
-
-
Drzezga, A.1
Riemenschneider, M.2
Strassner, B.3
-
15
-
-
0037065999
-
The effect of APOE epsilon4 allele on cerebral glucose metabolism in AD is a function of age at onset
-
Hirono N, Hashimoto M, Yasuda M, et al. The effect of APOE epsilon4 allele on cerebral glucose metabolism in AD is a function of age at onset. Neurology 2002;58:743- 750.
-
(2002)
Neurology
, vol.58
, pp. 743-750
-
-
Hirono, N.1
Hashimoto, M.2
Yasuda, M.3
-
16
-
-
0032588382
-
Apolipoprotein E epsilon4 allele, temporal lobe atrophy, and white matter lesions in late-life dementias
-
Barber R, Gholkar A, Scheltens P, et al. Apolipoprotein E epsilon4 allele, temporal lobe atrophy, and white matter lesions in late-life dementias. Arch Neurol 1999;56:961- 965.
-
(1999)
Arch Neurol
, vol.56
, pp. 961-965
-
-
Barber, R.1
Gholkar, A.2
Scheltens, P.3
-
17
-
-
0035940362
-
Apolipoprotein E epsilon 4 and the pattern of regional brain atrophy in Alzheimer's disease
-
Hashimoto M, Yasuda M, Tanimukai S, et al. Apolipoprotein E epsilon 4 and the pattern of regional brain atrophy in Alzheimer's disease. Neurology 2001;57:1461-1466.
-
(2001)
Neurology
, vol.57
, pp. 1461-1466
-
-
Hashimoto, M.1
Yasuda, M.2
Tanimukai, S.3
-
18
-
-
0036152408
-
Accelerated hippocampal atrophy in Alzheimer's disease with apolipoprotein E epsilon4 allele
-
Mori E, Lee K, Yasuda M, et al. Accelerated hippocampal atrophy in Alzheimer's disease with apolipoprotein E epsilon4 allele. Ann Neurol 2002;51:209-214.
-
(2002)
Ann Neurol
, vol.51
, pp. 209-214
-
-
Mori, E.1
Lee, K.2
Yasuda, M.3
-
19
-
-
0031596169
-
-
Yasuda M, Mori E, Kitagaki H, et al. Apolipoprotein E epsilon 4 allele and whole brain atrophy in late-onset Alzheimer's disease. Am J Psychiatry 1998;155:779-784.
-
Yasuda M, Mori E, Kitagaki H, et al. Apolipoprotein E epsilon 4 allele and whole brain atrophy in late-onset Alzheimer's disease. Am J Psychiatry 1998;155:779-784.
-
-
-
-
20
-
-
36149001032
-
Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease
-
Drzezga A, Grimmer T, Henriksen G, et al. Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease. Neuroimage 2008;39:619-633.
-
(2008)
Neuroimage
, vol.39
, pp. 619-633
-
-
Drzezga, A.1
Grimmer, T.2
Henriksen, G.3
-
21
-
-
10744232413
-
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
-
Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol 2004;55:306-319.
-
(2004)
Ann Neurol
, vol.55
, pp. 306-319
-
-
Klunk, W.E.1
Engler, H.2
Nordberg, A.3
-
22
-
-
4644283049
-
PET imaging of amyloid in Alzheimer's disease
-
Nordberg A. PET imaging of amyloid in Alzheimer's disease. Lancet Neurol 2004;3:519-527.
-
(2004)
Lancet Neurol
, vol.3
, pp. 519-527
-
-
Nordberg, A.1
-
23
-
-
34248579291
-
Imaging betaamyloid burden in aging and dementia
-
Rowe CC, Ng S, Ackermann U, et al. Imaging betaamyloid burden in aging and dementia. Neurology 2007; 68:1718-1725.
-
(2007)
Neurology
, vol.68
, pp. 1718-1725
-
-
Rowe, C.C.1
Ng, S.2
Ackermann, U.3
-
24
-
-
33748692453
-
Evaluation of voxel-based methods for the statistical analysis of PIB PET amyloid imaging studies in Alzheimer's disease
-
Ziolko SK, Weissfeld LA, Klunk WE, et al. Evaluation of voxel-based methods for the statistical analysis of PIB PET amyloid imaging studies in Alzheimer's disease. Neuroimage 2006;33:94-102.
-
(2006)
Neuroimage
, vol.33
, pp. 94-102
-
-
Ziolko, S.K.1
Weissfeld, L.A.2
Klunk, W.E.3
-
25
-
-
39749108812
-
11]C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment
-
Jack CR Jr, Lowe VJ, Senjem ML, et al. [11]C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain 2008;131:665-680.
-
(2008)
Brain
, vol.131
, pp. 665-680
-
-
Jack Jr, C.R.1
Lowe, V.J.2
Senjem, M.L.3
-
26
-
-
0036334830
-
Thresholding of statistical maps in functional neuroimaging using the false discovery rate
-
Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 2002;15:870-878.
-
(2002)
Neuroimage
, vol.15
, pp. 870-878
-
-
Genovese, C.R.1
Lazar, N.A.2
Nichols, T.3
-
28
-
-
63149107899
-
Hemispherespecific episodic memory networks in the human brain: A correlation study between intracarotid amobarbital test and [(18)F]FDG-PET
-
Akanuma N, Reed LJ, Marsden PK, et al. Hemispherespecific episodic memory networks in the human brain: a correlation study between intracarotid amobarbital test and [(18)F]FDG-PET. J Cogn Neurosci 2009;21:605- 622.
-
(2009)
J Cogn Neurosci
, vol.21
, pp. 605-622
-
-
Akanuma, N.1
Reed, L.J.2
Marsden, P.K.3
-
29
-
-
33747048954
-
11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease
-
Mintun MA, Larossa GN, Sheline YI, et al. [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology 2006;67:446-452.
-
(2006)
Neurology
, vol.67
, pp. 446-452
-
-
Mintun, M.A.1
Larossa, G.N.2
Sheline, Y.I.3
-
30
-
-
0032544377
-
Apolipoprotein E polymorphism influences the cerebral metabolic pattern in Alzheimer's disease
-
Mielke R, Zerres K, Uhlhaas S, Kessler J, Heiss WD. Apolipoprotein E polymorphism influences the cerebral metabolic pattern in Alzheimer's disease. Neurosci Lett 1998; 254:49-52.
-
(1998)
Neurosci Lett
, vol.254
, pp. 49-52
-
-
Mielke, R.1
Zerres, K.2
Uhlhaas, S.3
Kessler, J.4
Heiss, W.D.5
-
31
-
-
0034906436
-
In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease
-
Baron JC, Chetelat G, Desgranges B, et al. In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease. Neuroimage 2001;14:298-309.
-
(2001)
Neuroimage
, vol.14
, pp. 298-309
-
-
Baron, J.C.1
Chetelat, G.2
Desgranges, B.3
-
32
-
-
40449135167
-
Beta-amyloid burden is not associated with rates of brain atrophy
-
Josephs KA, Whitwell JL, Ahmed Z, et al. Beta-amyloid burden is not associated with rates of brain atrophy. Ann Neurol 2008;63:204-212.
-
(2008)
Ann Neurol
, vol.63
, pp. 204-212
-
-
Josephs, K.A.1
Whitwell, J.L.2
Ahmed, Z.3
-
33
-
-
4143139576
-
APOE genotype effects on Alzheimer's disease onset and epidemiology
-
Ashford JW. APOE genotype effects on Alzheimer's disease onset and epidemiology. J Mol Neurosci 2004;23: 157-165.
-
(2004)
J Mol Neurosci
, vol.23
, pp. 157-165
-
-
Ashford, J.W.1
-
34
-
-
21444461559
-
Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease?
-
Lambert JC, Mann D, Richard F, et al. Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease? J Neurol Neurosurg Psychiatry 2005;76: 928-933.
-
(2005)
J Neurol Neurosurg Psychiatry
, vol.76
, pp. 928-933
-
-
Lambert, J.C.1
Mann, D.2
Richard, F.3
-
35
-
-
0032875656
-
Apolipoprotein E isoforms and the development of low and high Braak stages of Alzheimer's disease-related lesions
-
Ohm TG, Scharnagl H, Marz W, Bohl J. Apolipoprotein E isoforms and the development of low and high Braak stages of Alzheimer's disease-related lesions. Acta Neuropathol 1999;98:273-280.
-
(1999)
Acta Neuropathol
, vol.98
, pp. 273-280
-
-
Ohm, T.G.1
Scharnagl, H.2
Marz, W.3
Bohl, J.4
-
36
-
-
14444285507
-
Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: Relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype
-
Berg L, McKeel DW Jr, Miller JP, et al. Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 1998;55:326-335.
-
(1998)
Arch Neurol
, vol.55
, pp. 326-335
-
-
Berg, L.1
McKeel Jr, D.W.2
Miller, J.P.3
-
37
-
-
67650454727
-
-
Grimmer T, Henriksen G, Wester HJ, et al. Clinical severity of Alzheimer's disease is associated with PIB uptake in PET. Neurobiol Aging Epub 2008 Mar 18.
-
Grimmer T, Henriksen G, Wester HJ, et al. Clinical severity of Alzheimer's disease is associated with PIB uptake in PET. Neurobiol Aging Epub 2008 Mar 18.
-
-
-
-
38
-
-
34848885454
-
PIB is a nonspecific imaging marker of amyloid-beta (Abeta) peptiderelated cerebral amyloidosis
-
Lockhart A, Lamb JR, Osredkar T, et al. PIB is a nonspecific imaging marker of amyloid-beta (Abeta) peptiderelated cerebral amyloidosis. Brain 2007;130:2607-2615.
-
(2007)
Brain
, vol.130
, pp. 2607-2615
-
-
Lockhart, A.1
Lamb, J.R.2
Osredkar, T.3
-
39
-
-
2942536666
-
Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease
-
Tiraboschi P, Hansen LA, Masliah E, Alford M, Thal LJ, Corey-Bloom J. Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease. Neurology 2004;62:1977-1983.
-
(2004)
Neurology
, vol.62
, pp. 1977-1983
-
-
Tiraboschi, P.1
Hansen, L.A.2
Masliah, E.3
Alford, M.4
Thal, L.J.5
Corey-Bloom, J.6
-
40
-
-
67650428377
-
Clinical trials of bapineuzumab a beta-amyloid-targeted immunotherapy in patients with mild-to-moderate Alzheimer's disease
-
Chicago
-
Grundman M, Black R. Clinical trials of bapineuzumab a beta-amyloid-targeted immunotherapy in patients with mild-to-moderate Alzheimer's disease. In: International Conference on Alzheimer's Disease (ICAD) 2008. Chicago: 2008.
-
(2008)
International Conference on Alzheimer's Disease (ICAD)
-
-
Grundman, M.1
Black, R.2
|