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Volumn 72, Issue 17, 2009, Pages 1487-1494

Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; CARBON 11; APOLIPOPROTEIN E4; BENZOTHIAZOLE DERIVATIVE; CARBON; DIAGNOSTIC AGENT; N METHYL 2 (4' METHYLAMINOPHENYL) 6 HYDROXYBENZOTHIAZOLE; N-METHYL-2-(4'-METHYLAMINOPHENYL)-6-HYDROXYBENZOTHIAZOLE;

EID: 67549147148     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181a2e8d0     Document Type: Article
Times cited : (229)

References (40)
  • 1
    • 0037469076 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease
    • Bennett DA, Wilson RS, Schneider JA, et al. Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease. Neurology 2003; 60:246-252.
    • (2003) Neurology , vol.60 , pp. 246-252
    • Bennett, D.A.1    Wilson, R.S.2    Schneider, J.A.3
  • 2
    • 0028841027 scopus 로고
    • Apolipoprotein E, dementia, and cortical deposition of beta-amyloid protein
    • Polvikoski T, Sulkava R, Haltia M, et al. Apolipoprotein E, dementia, and cortical deposition of beta-amyloid protein. N Engl J Med 1995;333:1242-1247.
    • (1995) N Engl J Med , vol.333 , pp. 1242-1247
    • Polvikoski, T.1    Sulkava, R.2    Haltia, M.3
  • 3
    • 38349146483 scopus 로고    scopus 로고
    • E and Alzheimer's disease: Molecular mechanisms and therapeutic opportunities
    • Cedazo-Minguez A. Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities. J Cell Mol Med 2007;11:1227-1238.
    • (2007) J Cell Mol Med , vol.11 , pp. 1227-1238
    • Apolipoprotein, C.-M.A.1
  • 4
    • 0032829336 scopus 로고    scopus 로고
    • Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are diseaserelated and apolipoprotein E genotype dependent
    • Beffert U, Cohn JS, Petit-Turcotte C, et al. Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are diseaserelated and apolipoprotein E genotype dependent. Brain Res 1999;843:87-94.
    • (1999) Brain Res , vol.843 , pp. 87-94
    • Beffert, U.1    Cohn, J.S.2    Petit-Turcotte, C.3
  • 5
    • 0030696944 scopus 로고    scopus 로고
    • Roses AD. Apolipoprotein E, a gene with complex biological interactions in the aging brain. Neurobiol Dis 1997;4: 170-185.
    • Roses AD. Apolipoprotein E, a gene with complex biological interactions in the aging brain. Neurobiol Dis 1997;4: 170-185.
  • 6
    • 0036130129 scopus 로고    scopus 로고
    • Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: Mechanistic implications for apoE4 enhanced amyloid burden and risk for Alzheimer's disease
    • Esler WP, Marshall JR, Stimson ER, et al. Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: mechanistic implications for apoE4 enhanced amyloid burden and risk for Alzheimer's disease. Amyloid 2002;9:1-12.
    • (2002) Amyloid , vol.9 , pp. 1-12
    • Esler, W.P.1    Marshall, J.R.2    Stimson, E.R.3
  • 7
    • 0031021296 scopus 로고    scopus 로고
    • Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele
    • Arendt T, Schindler C, Bruckner MK, et al. Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele. J Neurosci 1997;17:516-529.
    • (1997) J Neurosci , vol.17 , pp. 516-529
    • Arendt, T.1    Schindler, C.2    Bruckner, M.K.3
  • 8
    • 40849111266 scopus 로고    scopus 로고
    • Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions
    • Reiman EM, Chen K, Caselli RJ, et al. Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions. Neuroimage 2008;40: 1214-1221.
    • (2008) Neuroimage , vol.40 , pp. 1214-1221
    • Reiman, E.M.1    Chen, K.2    Caselli, R.J.3
  • 9
    • 44649190480 scopus 로고    scopus 로고
    • Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers
    • Burggren AC, Zeineh MM, Ekstrom AD, et al. Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers. Neuroimage 2008;41:1177-1183.
    • (2008) Neuroimage , vol.41 , pp. 1177-1183
    • Burggren, A.C.1    Zeineh, M.M.2    Ekstrom, A.D.3
  • 10
    • 34250801552 scopus 로고    scopus 로고
    • Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates
    • Chen K, Reiman EM, Alexander GE, et al. Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates. Am J Psychiatry 2007;164:916-921.
    • (2007) Am J Psychiatry , vol.164 , pp. 916-921
    • Chen, K.1    Reiman, E.M.2    Alexander, G.E.3
  • 11
    • 34248324435 scopus 로고    scopus 로고
    • Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: An observational study
    • Shaw P, Lerch JP, Pruessner JC, et al. Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study. Lancet Neurol 2007;6:494-500.
    • (2007) Lancet Neurol , vol.6 , pp. 494-500
    • Shaw, P.1    Lerch, J.P.2    Pruessner, J.C.3
  • 12
    • 33644697324 scopus 로고    scopus 로고
    • Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET
    • Drzezga A, Grimmer T, Riemenschneider M, et al. Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET. J Nucl Med 2005;46:1625-1632.
    • (2005) J Nucl Med , vol.46 , pp. 1625-1632
    • Drzezga, A.1    Grimmer, T.2    Riemenschneider, M.3
  • 13
    • 40449102563 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon 4 allele is associated with increased atrophy in progressive mild cognitive impairment: A voxelbased morphometric study
    • Hamalainen A, Grau-Olivares M, Tervo S, et al. Apolipoprotein E epsilon 4 allele is associated with increased atrophy in progressive mild cognitive impairment: a voxelbased morphometric study. Neurodegen Dis 2008;5:186- 189.
    • (2008) Neurodegen Dis , vol.5 , pp. 186-189
    • Hamalainen, A.1    Grau-Olivares, M.2    Tervo, S.3
  • 14
    • 19944427952 scopus 로고    scopus 로고
    • Cerebral glucose metabolism in patients with AD and different APOE genotypes
    • Drzezga A, Riemenschneider M, Strassner B, et al. Cerebral glucose metabolism in patients with AD and different APOE genotypes. Neurology 2005;64:102-107.
    • (2005) Neurology , vol.64 , pp. 102-107
    • Drzezga, A.1    Riemenschneider, M.2    Strassner, B.3
  • 15
    • 0037065999 scopus 로고    scopus 로고
    • The effect of APOE epsilon4 allele on cerebral glucose metabolism in AD is a function of age at onset
    • Hirono N, Hashimoto M, Yasuda M, et al. The effect of APOE epsilon4 allele on cerebral glucose metabolism in AD is a function of age at onset. Neurology 2002;58:743- 750.
    • (2002) Neurology , vol.58 , pp. 743-750
    • Hirono, N.1    Hashimoto, M.2    Yasuda, M.3
  • 16
    • 0032588382 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 allele, temporal lobe atrophy, and white matter lesions in late-life dementias
    • Barber R, Gholkar A, Scheltens P, et al. Apolipoprotein E epsilon4 allele, temporal lobe atrophy, and white matter lesions in late-life dementias. Arch Neurol 1999;56:961- 965.
    • (1999) Arch Neurol , vol.56 , pp. 961-965
    • Barber, R.1    Gholkar, A.2    Scheltens, P.3
  • 17
    • 0035940362 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon 4 and the pattern of regional brain atrophy in Alzheimer's disease
    • Hashimoto M, Yasuda M, Tanimukai S, et al. Apolipoprotein E epsilon 4 and the pattern of regional brain atrophy in Alzheimer's disease. Neurology 2001;57:1461-1466.
    • (2001) Neurology , vol.57 , pp. 1461-1466
    • Hashimoto, M.1    Yasuda, M.2    Tanimukai, S.3
  • 18
    • 0036152408 scopus 로고    scopus 로고
    • Accelerated hippocampal atrophy in Alzheimer's disease with apolipoprotein E epsilon4 allele
    • Mori E, Lee K, Yasuda M, et al. Accelerated hippocampal atrophy in Alzheimer's disease with apolipoprotein E epsilon4 allele. Ann Neurol 2002;51:209-214.
    • (2002) Ann Neurol , vol.51 , pp. 209-214
    • Mori, E.1    Lee, K.2    Yasuda, M.3
  • 19
    • 0031596169 scopus 로고    scopus 로고
    • Yasuda M, Mori E, Kitagaki H, et al. Apolipoprotein E epsilon 4 allele and whole brain atrophy in late-onset Alzheimer's disease. Am J Psychiatry 1998;155:779-784.
    • Yasuda M, Mori E, Kitagaki H, et al. Apolipoprotein E epsilon 4 allele and whole brain atrophy in late-onset Alzheimer's disease. Am J Psychiatry 1998;155:779-784.
  • 20
    • 36149001032 scopus 로고    scopus 로고
    • Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease
    • Drzezga A, Grimmer T, Henriksen G, et al. Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease. Neuroimage 2008;39:619-633.
    • (2008) Neuroimage , vol.39 , pp. 619-633
    • Drzezga, A.1    Grimmer, T.2    Henriksen, G.3
  • 21
    • 10744232413 scopus 로고    scopus 로고
    • Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
    • Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol 2004;55:306-319.
    • (2004) Ann Neurol , vol.55 , pp. 306-319
    • Klunk, W.E.1    Engler, H.2    Nordberg, A.3
  • 22
    • 4644283049 scopus 로고    scopus 로고
    • PET imaging of amyloid in Alzheimer's disease
    • Nordberg A. PET imaging of amyloid in Alzheimer's disease. Lancet Neurol 2004;3:519-527.
    • (2004) Lancet Neurol , vol.3 , pp. 519-527
    • Nordberg, A.1
  • 23
    • 34248579291 scopus 로고    scopus 로고
    • Imaging betaamyloid burden in aging and dementia
    • Rowe CC, Ng S, Ackermann U, et al. Imaging betaamyloid burden in aging and dementia. Neurology 2007; 68:1718-1725.
    • (2007) Neurology , vol.68 , pp. 1718-1725
    • Rowe, C.C.1    Ng, S.2    Ackermann, U.3
  • 24
    • 33748692453 scopus 로고    scopus 로고
    • Evaluation of voxel-based methods for the statistical analysis of PIB PET amyloid imaging studies in Alzheimer's disease
    • Ziolko SK, Weissfeld LA, Klunk WE, et al. Evaluation of voxel-based methods for the statistical analysis of PIB PET amyloid imaging studies in Alzheimer's disease. Neuroimage 2006;33:94-102.
    • (2006) Neuroimage , vol.33 , pp. 94-102
    • Ziolko, S.K.1    Weissfeld, L.A.2    Klunk, W.E.3
  • 25
    • 39749108812 scopus 로고    scopus 로고
    • 11]C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment
    • Jack CR Jr, Lowe VJ, Senjem ML, et al. [11]C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain 2008;131:665-680.
    • (2008) Brain , vol.131 , pp. 665-680
    • Jack Jr, C.R.1    Lowe, V.J.2    Senjem, M.L.3
  • 26
    • 0036334830 scopus 로고    scopus 로고
    • Thresholding of statistical maps in functional neuroimaging using the false discovery rate
    • Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 2002;15:870-878.
    • (2002) Neuroimage , vol.15 , pp. 870-878
    • Genovese, C.R.1    Lazar, N.A.2    Nichols, T.3
  • 28
    • 63149107899 scopus 로고    scopus 로고
    • Hemispherespecific episodic memory networks in the human brain: A correlation study between intracarotid amobarbital test and [(18)F]FDG-PET
    • Akanuma N, Reed LJ, Marsden PK, et al. Hemispherespecific episodic memory networks in the human brain: a correlation study between intracarotid amobarbital test and [(18)F]FDG-PET. J Cogn Neurosci 2009;21:605- 622.
    • (2009) J Cogn Neurosci , vol.21 , pp. 605-622
    • Akanuma, N.1    Reed, L.J.2    Marsden, P.K.3
  • 29
    • 33747048954 scopus 로고    scopus 로고
    • 11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease
    • Mintun MA, Larossa GN, Sheline YI, et al. [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology 2006;67:446-452.
    • (2006) Neurology , vol.67 , pp. 446-452
    • Mintun, M.A.1    Larossa, G.N.2    Sheline, Y.I.3
  • 30
    • 0032544377 scopus 로고    scopus 로고
    • Apolipoprotein E polymorphism influences the cerebral metabolic pattern in Alzheimer's disease
    • Mielke R, Zerres K, Uhlhaas S, Kessler J, Heiss WD. Apolipoprotein E polymorphism influences the cerebral metabolic pattern in Alzheimer's disease. Neurosci Lett 1998; 254:49-52.
    • (1998) Neurosci Lett , vol.254 , pp. 49-52
    • Mielke, R.1    Zerres, K.2    Uhlhaas, S.3    Kessler, J.4    Heiss, W.D.5
  • 31
    • 0034906436 scopus 로고    scopus 로고
    • In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease
    • Baron JC, Chetelat G, Desgranges B, et al. In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease. Neuroimage 2001;14:298-309.
    • (2001) Neuroimage , vol.14 , pp. 298-309
    • Baron, J.C.1    Chetelat, G.2    Desgranges, B.3
  • 32
    • 40449135167 scopus 로고    scopus 로고
    • Beta-amyloid burden is not associated with rates of brain atrophy
    • Josephs KA, Whitwell JL, Ahmed Z, et al. Beta-amyloid burden is not associated with rates of brain atrophy. Ann Neurol 2008;63:204-212.
    • (2008) Ann Neurol , vol.63 , pp. 204-212
    • Josephs, K.A.1    Whitwell, J.L.2    Ahmed, Z.3
  • 33
    • 4143139576 scopus 로고    scopus 로고
    • APOE genotype effects on Alzheimer's disease onset and epidemiology
    • Ashford JW. APOE genotype effects on Alzheimer's disease onset and epidemiology. J Mol Neurosci 2004;23: 157-165.
    • (2004) J Mol Neurosci , vol.23 , pp. 157-165
    • Ashford, J.W.1
  • 34
    • 21444461559 scopus 로고    scopus 로고
    • Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease?
    • Lambert JC, Mann D, Richard F, et al. Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease? J Neurol Neurosurg Psychiatry 2005;76: 928-933.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 928-933
    • Lambert, J.C.1    Mann, D.2    Richard, F.3
  • 35
    • 0032875656 scopus 로고    scopus 로고
    • Apolipoprotein E isoforms and the development of low and high Braak stages of Alzheimer's disease-related lesions
    • Ohm TG, Scharnagl H, Marz W, Bohl J. Apolipoprotein E isoforms and the development of low and high Braak stages of Alzheimer's disease-related lesions. Acta Neuropathol 1999;98:273-280.
    • (1999) Acta Neuropathol , vol.98 , pp. 273-280
    • Ohm, T.G.1    Scharnagl, H.2    Marz, W.3    Bohl, J.4
  • 36
    • 14444285507 scopus 로고    scopus 로고
    • Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: Relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype
    • Berg L, McKeel DW Jr, Miller JP, et al. Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 1998;55:326-335.
    • (1998) Arch Neurol , vol.55 , pp. 326-335
    • Berg, L.1    McKeel Jr, D.W.2    Miller, J.P.3
  • 37
    • 67650454727 scopus 로고    scopus 로고
    • Grimmer T, Henriksen G, Wester HJ, et al. Clinical severity of Alzheimer's disease is associated with PIB uptake in PET. Neurobiol Aging Epub 2008 Mar 18.
    • Grimmer T, Henriksen G, Wester HJ, et al. Clinical severity of Alzheimer's disease is associated with PIB uptake in PET. Neurobiol Aging Epub 2008 Mar 18.
  • 38
    • 34848885454 scopus 로고    scopus 로고
    • PIB is a nonspecific imaging marker of amyloid-beta (Abeta) peptiderelated cerebral amyloidosis
    • Lockhart A, Lamb JR, Osredkar T, et al. PIB is a nonspecific imaging marker of amyloid-beta (Abeta) peptiderelated cerebral amyloidosis. Brain 2007;130:2607-2615.
    • (2007) Brain , vol.130 , pp. 2607-2615
    • Lockhart, A.1    Lamb, J.R.2    Osredkar, T.3
  • 39
    • 2942536666 scopus 로고    scopus 로고
    • Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease
    • Tiraboschi P, Hansen LA, Masliah E, Alford M, Thal LJ, Corey-Bloom J. Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease. Neurology 2004;62:1977-1983.
    • (2004) Neurology , vol.62 , pp. 1977-1983
    • Tiraboschi, P.1    Hansen, L.A.2    Masliah, E.3    Alford, M.4    Thal, L.J.5    Corey-Bloom, J.6
  • 40
    • 67650428377 scopus 로고    scopus 로고
    • Clinical trials of bapineuzumab a beta-amyloid-targeted immunotherapy in patients with mild-to-moderate Alzheimer's disease
    • Chicago
    • Grundman M, Black R. Clinical trials of bapineuzumab a beta-amyloid-targeted immunotherapy in patients with mild-to-moderate Alzheimer's disease. In: International Conference on Alzheimer's Disease (ICAD) 2008. Chicago: 2008.
    • (2008) International Conference on Alzheimer's Disease (ICAD)
    • Grundman, M.1    Black, R.2


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