fMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer disease

Neurology

Volumn 64, Issue 3, 2005, Pages 501-508

  Bondi, Mark W ^a,b   Houston, Wes S ^a   Eyler, Lisa T ^a   Brown, Gregory G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; BLOOD OXYGENATION; BRAIN FUNCTION; CONTROLLED STUDY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENETIC RISK; GENOTYPE; HIPPOCAMPUS; HUMAN; LEARNING; MALE; MEMORY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; VERBALIZATION;

EID: 13244274910     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000150885.00929.7E     Document Type: Article

References (58)

1. Albert MS, Moss MB, Tanzi R, Jones K. Preclinical prediction of AD using neuropsychological tests. J Int Neuropsychol Soc 2001;7:631-639.
2. Bäckman L, Small BJ, Fratiglioni L. Stability of the preclinical episodic memory deficit in Alzheimer's disease. Brain 2001;124:96-102.
3. Bondi MW, Monsch AU, Galasko D, Butters N, Salmon DP, Delis DC. Preclinical cognitive markers of dementia of the Alzheimer type. Neuropsychology 1994;8:374-384.
4. Chen P, Ratcliff G, Belle SH, Cauley JA, DeKosky ST, Ganguli M. Patterns of cognitive decline in presymptomatic Alzheimer disease: a prospective community study. Arch Gen Psychiatry 2001;58:853-858.
5. Fuld PA, Masur DM, Blau AD, Crystal H, Aronson MK. Object-memory evaluation for prospective detection of dementia in normal functioning elderly: predictive and normative data. J Clin Exp Neuropsychol 1990;12:520-528.
6. Grober E, Kawas C. Learning and retention in preclinical and early Alzheimer's disease. Psychol Aging 1997;12:183-188.
7. Howieson DB, Dame A, Camicioli R, Sexton G, Payami H, Kaye JA. Cognitive markers preceding Alzheimer's dementia in the healthy oldest old. J Am Geriatr Soc 1997;45:584-589.
8. Bondi MW, Salmon DP, Galasko D, Thomas RG, Thal LJ. Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease. Psychol Aging 1999;14:295-303.
9. Smith GE, Bohac DL, Waring SC, et al. Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects. Neurology 1998;50:355-362.
10. Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993;261:921-923.
11. Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-1472.
12. Soininen H, Partanen K, Pitkanen A, et al. Decreased hippocampal volume asymmetry on MRIs in nondemented elderly subjects carrying the apolipoprotein E epsilon 4 allele. Neurology 1995;45:391-392.
13. Plassman BL, Welsh-Bohmer KA, Bigler ED, et al. Apolipoprotein E ε4 allele and hippocampal volume in twin with normal cognition. Neurology 1997;48:985-989.
14. Reiman EM, Caselli RJ, Yun LS, et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the ε4 allele for APOE. N Engl J Med 1996;334:752-758.
15. Lange KL, Bondi MW, Galasko DG, Delis DC, Salmon DP, Thal LJ. Decline in verbal memory during preclinical Alzheimer's disease: examination of the effect of apolipoprotein E genotype. J Int Neuropsychol Soc 2002;8:943-955.
16. Ghebremedhin E, Schultz C, Braak E, Braak H. High frequency of apolipoprotein E ε4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes. Exp Neurol 1998;153:152-155.
17. Petersen RC, Stevens JC, Ganguli M, Tangalos EG, Cummings JL, DeKosky ST. Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review). Neurology 2001;56: 1133-1142.
18. Desgranges B, Baron J-C, Eustache F. The functional neuroanatomy of episodic memory: the role of the frontal lobes, the hippocampal formation, and other areas. NeuroImage 1998;8:198-213.
19. Bookheimer SY, Strojwas MH, Cohen MS, et al. Patterns of brain activation in people at risk for Alzheimer's disease. N Engl J Med 2000;343:450-456.
20. Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1983;17:37-49.
21. Wechsler D. Wechsler Memory Scale-Revised. New York: Psychological Corporation, 1987.
22. Delis DC, Kramer JH, Kaplan E, Ober BA. The California Verbal Learning Test. New York: Psychological Corporation, 1987.
23. Stern CE, Corkin S, Gonzaalez RG, et al. The hippocampal formation participates in novel picture encoding: evidence from functional magnetic resonance imaging. Proc Natl Acad Sci 1996;93:8660-8665.
24. Cox RW. AFNI. Software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res 1996;29:162-173.
25. Talairach J, Tournoux P. A coplanar stereotaxic atlas of the human brain. New York, NY, 1988.
26. Eyler Zorrilla LT, Jeste DV, Paulus M, Brown GG. Functional abnormalities of medial cortex during novel picture learning among patients with chronic schizophrenia. Schiz Res 2003;59:187-198.
27. Nyberg L, Persson J, Habib R, et al. Large scale neurocognitive networks underlying episodic memory. J Cogn Neurosci 2000;12:163-173.
28. Gabrieli JDE, Brewer JB, Desmond JE, Glover GH. Separate neural bases of two fundamental memory processes in the human medial temporal lobe. Science 1997;276:264-266.
29. Constable RT, Carpentier A, Pugh K, Westerveld M, Oszunar Y, Spencer DD. Investigation of the human hippocampal formation using a randomized event-related paradigm and Z-shimmed functional MRI. Neuroimage 2000;12:55-62.
30. Lancaster JL, Woldroff MG, Parsons LM, et al. Automated Talairach atlas labels for functional brain mapping. Hum Brain Mapp 2000;10:120-131.
31. Eyler Zorrilla LT, Jeste DV, Brown GG. Functional MRI and novel picture-learning among older patients with chronic schizophrenia: abnormal correlations between recognition memory and medial temporal brain response. Am J Geriatr Psychiatry 2002;10:52-61.
32. Callicott JH, Ramsey NF, Tallent K, et al. Functional magnetic resonance imaging brain mapping in psychiatry: methodological issues illustrated in a study of working memory in schizophrenia. Neuropsychopharmacol 1998;18:186-196.
33. D'Esposito M, Zarahn E, Aguirre GK, Rypma B. The effect of normal aging on the coupling of neural activity to the BOLD hemodynamic response. NeuroImage 1999;10:6-14.
34. Sled JG, Zijdenbos AP, Evans AC. A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 1998;17:87-97.
35. Segonne F, Dale AM, Busa E, et al. A hybrid approach to the skull stripping problem in MRI. Organization for Human Brain Mapping, Brighton, UK. NeuroImage 2001;S241.
36. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp 2002;17:143-155.
37. Ward BD. Intracranial segmentation. Milwaukee, WI; Biophysics Research Institute, Medical College of Wisconsin. 1999. Available at: http://afni.nimh.nih.gov/afni/index/shtml.
38. Nelder JA, Mead R. A simplex method for function minimization. Comp J 1965;7:308-313.
39. Courchesne E, Chisum HJ, Townsend J, et al. Normal brain development and aging: quantitative analysis at in vivo MR imaging in healthy volunteers. Radiology 2000;216:672-682.
40. Becker JT, Mintum MA, Aleva K, Wiseman MB, Nichols T, DeKosky ST. Compensatory reallocation of brain resources supporting verbal episodic memory in Alzheimer's disease. Neurology 1996;46:692-700.
41. Grady CL, McIntosh AR, Beig S, Keightley ML, Burian H, Black SE. Evidence from functional neuroimaging of a compensatory prefrontal network in Alzheimer's disease. J Neurosci 2003;23:986-993.
42. Sperling RA, Bates JF, Chua EF, et al. fMRI studies of associative encoding in young and elderly controls and mild Alzheimer's disease. J Neurol Neurosurg Psychiatry 2003;74:44-50.
43. Durany N, Michel T, Kurt J, Cruz-Sanchez FF, Cervas-Navarro J, Riederer P. Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease. Int J Dev Neuroscí 2000;18:807-813.
44. Egan MF, Kojima M, Callicott JH, et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003;112:257-269.
45. DeKosky ST, Ikonomovic MD, Styren SD, et al. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann Neurol 2002;51:145-155.
46. Rombouts SA, Barkhof F, van Meel CS, Scheltens P. Alterations in brain activation during cholinergic enhancement with rivastigmine in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2002;73:665-671.
47. Machulda MM, Ward HA, Borowski B, et al. Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients. Neurology 2003;61:500-506.
48. Daselaar SM, Veltman DJ, Rombouts SA, Raaijmakers JG, Jonker C. Neuroanatomical correlates of episodic encoding and retrieval in young and elderly subjects. Brain 2003;126:43-56.
49. Smith CD, Andersen AH, Kryscio RJ, et al. Altered brain activation in cognitively intact individuals at high risk for Alzheimer's disease. Neurology 1999;53:1391-1396.
50. Cohen ER, Ugurbil K, Kim S-G. Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response. J Cereb Blood Flow Metab 2002;22:1042-1053.
51. Greicius MD, Srivastava G, Reiss AL, Menon V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Nat Acad Sci 2004;101:4637-4642.
52. Mueggler T, Sturchler-Pierrat C, Baumann D, Rausch M, Staufenbiel M, Rudin M. Compromised hemodynamic response in amyloid precursor protein transgenic mice. J Neurosci 2002;22:7218-7224.
53. Buckner RL, Snyder AZ, Sanders AL, Raichle ME, Morris JE. Functional brain imaging of young, nondemented, and demented older adults. J Cog Neurosci 2000;12:24-34.
54. Small SA, Chawla MK, Buonocore M, Rapp PR, Barnes CA. Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging. Proc Natl Acad Sci 2004;101:7181-7186.
55. Johnson SC, Saykin AJ, Baxter LC, Flashman LA, McAllister TW, Sparling M. Brain activation on fMRI and verbal memory ability: functional neuroanatomic correlates of CVLT performance. J Int Neuropsychol Soc 2001;7:55-62.
56. Vandenbroucke MWG, Goekoop R, Duschek EJJ, et al. Interindividual differences of medial temporal lobe activation during encoding in an elderly population studies by fMRI. NeuroImage 2003;21:173-180.
57. Reiman EM, Chen K, Alexander G, et al. Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc Natl Acad Sci 2004;101:284-289.
58. Mattis S. Dementia Rating Scale: Professional Manual. Odessa, FL: Psychological Assessment Resources, 1988.