Oxime K027: Novel low-toxic candidate for the universal reactivator of nerve agent-and pesticide-inhibited acetylcholinesterase

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 25, Issue 4, 2010, Pages 509-512

  Kuca, Kamil ^a,b,c   Musilek, Kamil ^b,c   Jun, Daniel ^a,b   Pohanka, Miroslav ^a   Ghosh, Kallol Kumar ^d   Hrabinova, Martina ^a  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

^c J E PURKINJE UNIVERSITY   (Czech Republic)

^d PT RAVISHANKAR SHUKLA UNIVERSITY   (India)

Author keywords

Acetylcholinesterase; Antidote; K027; Nerve agent; Oxime; Pesticide; Reactivator; Universal

Indexed keywords

(1 (4 HYDROXYIMINOMETHYLPYRIDINIUM) 3 (4 CARBAMOYLPYRIDINIUM)PROPANE DIBROMIDE; CHLORPYRIFOS METHYL; CHOLINESTERASE INHIBITOR; CYCLOSARIN; DICHLORVOS; K 027; OBIDOXIME; ORGANOPHOSPHATE PESTICIDE; OXIME DERIVATIVE; PARAOXON; PESTICIDE; SARIN; SOMAN; TABUN; UNCLASSIFIED DRUG; 1-(4-HYDROXYIMINOMETHYLPYRIDINIUM)-3-(CARBAMOYLPYRIDINIUM) PROPANE DIBROMIDE; ANTIDOTE; CHEMICAL WARFARE AGENT; CHOLINESTERASE REACTIVATOR; OXIME; PYRIDINIUM DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG INHIBITION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; RAT; EVALUATION STUDY;

ANTIDOTES; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; OXIMES; PESTICIDES; PYRIDINIUM COMPOUNDS;

EID: 77954395363     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756360903357569     Document Type: Article

References (46)

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