-
2
-
-
41749115459
-
Oximes in cyclosarin poisoning: Reactivation potency in vitro and therapeutic efficacy in vivo
-
L. Sevelova, K. Kuca, G. Krejcova, and D. Jun. Oximes in cyclosarin poisoning: Reactivation potency in vitro and therapeutic efficacy in vivo. Drug Met. Rev. 36: 99-99 (2004).
-
(2004)
Drug Met. Rev
, vol.36
, pp. 99-99
-
-
Sevelova, L.1
Kuca, K.2
Krejcova, G.3
Jun, D.4
-
3
-
-
41749125177
-
Five newoximes vs pralidoxime: Survival data from rats exposed to paraoxon
-
G.A. Petroianu, S.M. Nurulain, N. Nagelkerke, M. Al Sultan, A. Ain, K. Kuca, and J. Kassa. Five newoximes vs pralidoxime: Survival data from rats exposed to paraoxon. Crit. Care Med. 33: A52-A52 (2005).
-
(2005)
Crit. Care Med
, vol.33
-
-
Petroianu, G.A.1
Nurulain, S.M.2
Nagelkerke, N.3
Al Sultan, M.4
Ain, A.5
Kuca, K.6
Kassa, J.7
-
4
-
-
31044442395
-
In vitro and in vivo evaluation of pyridinium oximes: Mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity
-
M. Calic, A.L. Vrdoljak, M. Radic, D. Jelic, D. Jun, K. Kuca, and Z. Kovarik. In vitro and in vivo evaluation of pyridinium oximes: Mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity. Toxicology 219: 85-96 (2006).
-
(2006)
Toxicology
, vol.219
, pp. 85-96
-
-
Calic, M.1
Vrdoljak, A.L.2
Radic, M.3
Jelic, D.4
Jun, D.5
Kuca, K.6
Kovarik, Z.7
-
5
-
-
33847043946
-
Currently used cholinesterase reactivators against nerve agent intoxication: Comparison of their effectivity in vitro
-
K. Kuca, D. Jun, and J. Bajgar. Currently used cholinesterase reactivators against nerve agent intoxication: Comparison of their effectivity in vitro. Drug Chem. Toxicol. 30: 31-40 (2007).
-
(2007)
Drug Chem. Toxicol
, vol.30
, pp. 31-40
-
-
Kuca, K.1
Jun, D.2
Bajgar, J.3
-
6
-
-
33748654796
-
In vitro evaluation of acetylcholinesterase reactivators as potential antidotes against tabun nerve agent poisonings
-
K. Kuca, J. Cabal, D. Jun, and M. Hrabinova. In vitro evaluation of acetylcholinesterase reactivators as potential antidotes against tabun nerve agent poisonings. Drug Chem. Toxicol. 29: 443-449 (2006).
-
(2006)
Drug Chem. Toxicol
, vol.29
, pp. 443-449
-
-
Kuca, K.1
Cabal, J.2
Jun, D.3
Hrabinova, M.4
-
7
-
-
33846007716
-
Progress in synthesis of new acetylcholinesterase reactivators during the period 1990-2004
-
K. Musilek, K. Kuca, D. Jun, and M. Dolezal. Progress in synthesis of new acetylcholinesterase reactivators during the period 1990-2004. Curr. Org. Chem. 11: 229-238 (2007).
-
(2007)
Curr. Org. Chem
, vol.11
, pp. 229-238
-
-
Musilek, K.1
Kuca, K.2
Jun, D.3
Dolezal, M.4
-
8
-
-
19544367621
-
Design and synthesis of new bis-pyridinium oxime reactivators for acetyleholinesterase inhibited by organophosphorous nerve agents
-
T.H. Kim, K. Kuca, and D. Jun. Design and synthesis of new bis-pyridinium oxime reactivators for acetyleholinesterase inhibited by organophosphorous nerve agents. Bioorg. Med. Chem. Lett. 15: 2914-2917 (2005).
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 2914-2917
-
-
Kim, T.H.1
Kuca, K.2
Jun, D.3
-
9
-
-
34247096612
-
Development of the bisquaternary oxime HI-6 toward clinical use in the treatment of organophosphate nerve agent poisoning
-
P.M. Lundy, L. Raveh, and G. Amitai. Development of the bisquaternary oxime HI-6 toward clinical use in the treatment of organophosphate nerve agent poisoning. Toxicol. Rev. 25: 231-243 (2006).
-
(2006)
Toxicol. Rev
, vol.25
, pp. 231-243
-
-
Lundy, P.M.1
Raveh, L.2
Amitai, G.3
-
10
-
-
33646831462
-
Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: Survival in rats exposed to the organophosphate paraoxon
-
G.A. Petroianu, S.M. Nurulain, N. Nagelkerke, M.A.H. Al Sultan, K. Kuca, and J. Kassa. Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: survival in rats exposed to the organophosphate paraoxon. J. Appl. Toxicol. 26: 262-268 (2006).
-
(2006)
J. Appl. Toxicol
, vol.26
, pp. 262-268
-
-
Petroianu, G.A.1
Nurulain, S.M.2
Nagelkerke, N.3
Al Sultan, M.A.H.4
Kuca, K.5
Kassa, J.6
-
11
-
-
0346963355
-
Synthesis of bis-pyridinium oxime antidotes using bis(methylsulfonoxymethyl) ether for organophosphate nerve agents
-
G.Y. Yang, J.H. Yoon, C.M. Seong, N.S. Park, and Y.S. Jung. Synthesis of bis-pyridinium oxime antidotes using bis(methylsulfonoxymethyl) ether for organophosphate nerve agents. Bull. Kor. Chem. Soc. 24: 1368-1370 (2003).
-
(2003)
Bull. Kor. Chem. Soc
, vol.24
, pp. 1368-1370
-
-
Yang, G.Y.1
Yoon, J.H.2
Seong, C.M.3
Park, N.S.4
Jung, Y.S.5
-
12
-
-
41749096976
-
-
U.S. Patent 3,773,775
-
I. Hagedorn, U.S. Patent 3,773,775 (1973).
-
(1973)
-
-
Hagedorn, I.1
-
13
-
-
41749121464
-
-
U.S. Patent 4,128,651
-
I. Hagedorn, U.S. Patent 4,128,651 (1978).
-
(1978)
-
-
Hagedorn, I.1
-
14
-
-
0030604685
-
HI 6 dimethanesulfonate has better dissolution properties than HI 6 dichloride for application in dry/wet autoinjectors
-
H. Thiermann, S. Seidl, and P. Eyer. HI 6 dimethanesulfonate has better dissolution properties than HI 6 dichloride for application in dry/wet autoinjectors. Int. J. Pharm. 137: 167-176 (1996).
-
(1996)
Int. J. Pharm
, vol.137
, pp. 167-176
-
-
Thiermann, H.1
Seidl, S.2
Eyer, P.3
-
15
-
-
13444283404
-
The pharmacokinetics and pharmacodynamics of two HI-6 salts in swine and efficacy in the treatment of GF and soman poisoning
-
P.M. Lundy, I. Hill, P. Lecavalier, M.G. Hamilton, C. Vair, C. Davidson, K.L. Weatherby, and B.J. Berger. The pharmacokinetics and pharmacodynamics of two HI-6 salts in swine and efficacy in the treatment of GF and soman poisoning. Toxicology 208: 399-409 (2005).
-
(2005)
Toxicology
, vol.208
, pp. 399-409
-
-
Lundy, P.M.1
Hill, I.2
Lecavalier, P.3
Hamilton, M.G.4
Vair, C.5
Davidson, C.6
Weatherby, K.L.7
Berger, B.J.8
-
16
-
-
0028821653
-
Separation of geometrical syn and anti isomers of obidoxime by ion-pair high-performance liquid chromatography
-
U. Spöhrer and P. Eyer. Separation of geometrical syn and anti isomers of obidoxime by ion-pair high-performance liquid chromatography. J. Chromatogr. A 693: 55-61 (1995).
-
(1995)
J. Chromatogr. A
, vol.693
, pp. 55-61
-
-
Spöhrer, U.1
Eyer, P.2
-
17
-
-
28244442740
-
Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase
-
K. Musilek, K. Kuca, D. Jun, V. Dohnal, and M. Dolezal. Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase. J. Enzyme Inhib. Med. Chem. 20: 409-415 (2005).
-
(2005)
J. Enzyme Inhib. Med. Chem
, vol.20
, pp. 409-415
-
-
Musilek, K.1
Kuca, K.2
Jun, D.3
Dohnal, V.4
Dolezal, M.5
-
18
-
-
33748778822
-
Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase
-
K. Musilek, O. Holas, K. Kuca, D. Jun, V. Dohnal, and M. Dolezal. Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. Bioorg. Med. Chem. Lett. 16: 5673-5676 (2006).
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 5673-5676
-
-
Musilek, K.1
Holas, O.2
Kuca, K.3
Jun, D.4
Dohnal, V.5
Dolezal, M.6
-
19
-
-
33746992176
-
Bis-pyridiniumaldoxime reactivators connected with CH2O(CH2)(n)OCH2 linkers between pyridinium rings and their reactivity against VX
-
K.A. Oh, Y. Yang, D. Jun, K. Kuca, and Y.S. Jung. Bis-pyridiniumaldoxime reactivators connected with CH2O(CH2)(n)OCH2 linkers between pyridinium rings and their reactivity against VX. Bioorg Med. Chem. Lett. 16: 4852-4855 (2006).
-
(2006)
Bioorg Med. Chem. Lett
, vol.16
, pp. 4852-4855
-
-
Oh, K.A.1
Yang, Y.2
Jun, D.3
Kuca, K.4
Jung, Y.S.5
-
20
-
-
34748857779
-
TLC of quaternary pyridinium aldoximes, antidotes of organophosphorus esterase inhibitors
-
T. Csermely, G. Petroianu, K. Kuca, J. Furész, F. Darvas, Z. Gulyás, R. Laufer, and H. Kalász. TLC of quaternary pyridinium aldoximes, antidotes of organophosphorus esterase inhibitors. J. Planar Chromatogr. 20: 39-42 (2007).
-
(2007)
J. Planar Chromatogr
, vol.20
, pp. 39-42
-
-
Csermely, T.1
Petroianu, G.2
Kuca, K.3
Furész, J.4
Darvas, F.5
Gulyás, Z.6
Laufer, R.7
Kalász, H.8
|