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Volumn 27, Issue 5, 2007, Pages 482-490

Entry of two new asymmetric bispyridinium oximes (K-27 and K-48) into the rat brain: Comparison with obidoxime

Author keywords

Blood brain barrier; HPLC; Obidoxime; Organophosphate; Oxime; Paraoxon

Indexed keywords

BIS(PYRIDINIUM OXIME) DERIVATIVE; OBIDOXIME; ORGANOPHOSPHATE; PARAOXON;

EID: 34547922765     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1229     Document Type: Article
Times cited : (68)

References (29)
  • 1
    • 15744372981 scopus 로고    scopus 로고
    • Nerve gas - guidelines for care of victims of terrorism
    • Aas P, Jacobsen D. 2005. Nerve gas - guidelines for care of victims of terrorism. Tidsskr. Nor Laegeforen. 125: 731-735.
    • (2005) Tidsskr. Nor Laegeforen , vol.125 , pp. 731-735
    • Aas, P.1    Jacobsen, D.2
  • 2
    • 10044275708 scopus 로고    scopus 로고
    • Organophosphates/nerve agent poisoning: Mechanism of action, diagnosis, prophylaxis, and treatment
    • Bajgar J. 2004. Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment. Adv. Clin. Chem. 38: 151-216.
    • (2004) Adv. Clin. Chem , vol.38 , pp. 151-216
    • Bajgar, J.1
  • 3
    • 0015384142 scopus 로고
    • The influence of obidoxime on acetylcholinesterase activity in different parts of the mouse brain following isopropylmethyl phosphonofluoridate intoxication
    • Bajgar J, Jakl A, Hrdina V. 1972. The influence of obidoxime on acetylcholinesterase activity in different parts of the mouse brain following isopropylmethyl phosphonofluoridate intoxication. Eur. J. Pharmacol. 19: 199-202.
    • (1972) Eur. J. Pharmacol , vol.19 , pp. 199-202
    • Bajgar, J.1    Jakl, A.2    Hrdina, V.3
  • 4
    • 0032418115 scopus 로고    scopus 로고
    • Treatment of organophosphate poisoning. Experience of nerve agents and acute pesticide poisoning on the effects of oximes
    • Balali-Mood M, Shariat M. 1998. Treatment of organophosphate poisoning. Experience of nerve agents and acute pesticide poisoning on the effects of oximes. J. Physiol. Paris 92: 375-378.
    • (1998) J. Physiol. Paris , vol.92 , pp. 375-378
    • Balali-Mood, M.1    Shariat, M.2
  • 5
    • 33745204824 scopus 로고    scopus 로고
    • The need for translational research on antidotes for pesticide poisoning
    • Buckley NA, Eddleston M, Dawson AH. 2005a. The need for translational research on antidotes for pesticide poisoning. Clin. Exp. Pharmacol. Physiol. 32: 999-1005.
    • (2005) Clin. Exp. Pharmacol. Physiol , vol.32 , pp. 999-1005
    • Buckley, N.A.1    Eddleston, M.2    Dawson, A.H.3
  • 7
    • 4744354029 scopus 로고    scopus 로고
    • Specification of the structure of oximes able to reactivate tabun-inhibited acetylcholinesterase
    • Cabal J, Kuca K, Kassa J. 2004. Specification of the structure of oximes able to reactivate tabun-inhibited acetylcholinesterase. Basic Clin. Pharmacol. Toxicol. 95: 81-86.
    • (2004) Basic Clin. Pharmacol. Toxicol , vol.95 , pp. 81-86
    • Cabal, J.1    Kuca, K.2    Kassa, J.3
  • 8
    • 31044442395 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of pyridinium oximes: Mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity
    • Calic M, Vrdoljak AL, Radic B, Jelic D, Jun D, Kuca K, Kovarik Z. 2006. In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity. Toxicology 219: 85-96.
    • (2006) Toxicology , vol.219 , pp. 85-96
    • Calic, M.1    Vrdoljak, A.L.2    Radic, B.3    Jelic, D.4    Jun, D.5    Kuca, K.6    Kovarik, Z.7
  • 10
    • 2442702807 scopus 로고    scopus 로고
    • The role of oximes in the management of organophosphorus pesticide poisoning
    • Eyer P. 2003. The role of oximes in the management of organophosphorus pesticide poisoning. Toxicol. Rev. 22: 165-190.
    • (2003) Toxicol. Rev , vol.22 , pp. 165-190
    • Eyer, P.1
  • 11
    • 0014443454 scopus 로고
    • Penetration of 14C-obidoxime through the so-called blood-brain barrier of mice and rats
    • Falb A, Erdmann WD. 1969. Penetration of 14C-obidoxime through the so-called blood-brain barrier of mice and rats. Arch. Toxikol. 24: 123-132.
    • (1969) Arch. Toxikol , vol.24 , pp. 123-132
    • Falb, A.1    Erdmann, W.D.2
  • 12
    • 1642429319 scopus 로고
    • 14 into brain and the effect of cholinesterase inhibitors on its transport
    • 14 into brain and the effect of cholinesterase inhibitors on its transport. J. Pharmacol. Exp. Ther. 145: 252-265.
    • (1964) J. Pharmacol. Exp. Ther , vol.145 , pp. 252-265
    • Firemark, H.1    Barlow, C.F.2    Roth, L.J.3
  • 13
    • 1942437974 scopus 로고    scopus 로고
    • Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamates
    • Gupta RC. 2004. Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamates. Toxicol. Mech. Meth. 14: 103-143.
    • (2004) Toxicol. Mech. Meth , vol.14 , pp. 103-143
    • Gupta, R.C.1
  • 15
    • 0036447187 scopus 로고    scopus 로고
    • Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents
    • Kassa J. 2002. Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents. J. Toxicol. Clin. Toxicol. 6: 803-816.
    • (2002) J. Toxicol. Clin. Toxicol , vol.6 , pp. 803-816
    • Kassa, J.1
  • 16
    • 34547863689 scopus 로고    scopus 로고
    • A comparison of the potency of trimedoxime and other currently available oximes to reactivate tabun-inhibited acetylcholinesterase and eliminate acute toxic effects of tabun
    • Kassa J, Kuca K, Cabal J. 2005. A comparison of the potency of trimedoxime and other currently available oximes to reactivate tabun-inhibited acetylcholinesterase and eliminate acute toxic effects of tabun. Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub. 149: 419-423.
    • (2005) Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub , vol.149 , pp. 419-423
    • Kassa, J.1    Kuca, K.2    Cabal, J.3
  • 17
    • 33748444160 scopus 로고    scopus 로고
    • A comparison of the efficacy of new asymmetric bispyridinium oximes (K027, K048) with currently available oximes against tabun by in vivo methods
    • Kassa J, Kuca K, Cabal J, Paar M. 2006. A comparison of the efficacy of new asymmetric bispyridinium oximes (K027, K048) with currently available oximes against tabun by in vivo methods. J. Toxicol. Environ. Health A 69: 1875-1882.
    • (2006) J. Toxicol. Environ. Health A , vol.69 , pp. 1875-1882
    • Kassa, J.1    Kuca, K.2    Cabal, J.3    Paar, M.4
  • 19
    • 17444446525 scopus 로고    scopus 로고
    • Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase
    • Kuca K, Bielavsky J, Cabal J, Kassa J. 2003. Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase. Bioorg. Med. Chem. Lett. 13: 3545-3547.
    • (2003) Bioorg. Med. Chem. Lett , vol.13 , pp. 3545-3547
    • Kuca, K.1    Bielavsky, J.2    Cabal, J.3    Kassa, J.4
  • 23
    • 31344478996 scopus 로고    scopus 로고
    • Oxime therapy and outcomes in human organophosphate poisoning: An evaluation using meta-analytic techniques
    • Peter V, Moran JL, Graham P. 2006. Oxime therapy and outcomes in human organophosphate poisoning: An evaluation using meta-analytic techniques. Crit. Care Med. 34: 502-510.
    • (2006) Crit. Care Med , vol.34 , pp. 502-510
    • Peter, V.1    Moran, J.L.2    Graham, P.3
  • 24
    • 31644432758 scopus 로고    scopus 로고
    • Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: In vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon
    • Petroianu GA, Arafat K, Kuca K, Kassa J. 2006a. Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon. J. Appl. Toxicol. 26: 64-71.
    • (2006) J. Appl. Toxicol , vol.26 , pp. 64-71
    • Petroianu, G.A.1    Arafat, K.2    Kuca, K.3    Kassa, J.4
  • 26
    • 33646831462 scopus 로고    scopus 로고
    • Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: Survival in rats exposed to the organophosphate paraoxon
    • Petroianu GA, Nurulain SM, Nagelkerke N, Al-Sultan MA, Kuca K, Kassa J. 2006b. Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: survival in rats exposed to the organophosphate paraoxon. J. Appl. Toxicol. 26: 262-268.
    • (2006) J. Appl. Toxicol , vol.26 , pp. 262-268
    • Petroianu, G.A.1    Nurulain, S.M.2    Nagelkerke, N.3    Al-Sultan, M.A.4    Kuca, K.5    Kassa, J.6
  • 27
    • 0031830032 scopus 로고    scopus 로고
    • Control of blood pressure, heart rate and haematocrit during high-dose intravenous paraoxon exposure in mini pigs
    • Petroianu G, Toomes LM, Petroianu A, Bergler W, Rufer R. 1998. Control of blood pressure, heart rate and haematocrit during high-dose intravenous paraoxon exposure in mini pigs. J. Appl. Toxicol. 18: 293-298.
    • (1998) J. Appl. Toxicol , vol.18 , pp. 293-298
    • Petroianu, G.1    Toomes, L.M.2    Petroianu, A.3    Bergler, W.4    Rufer, R.5
  • 29
    • 33745976170 scopus 로고    scopus 로고
    • High-performance liquid chromatographic determination of the plasma concentration of K-27, a novel oxime-type cholinesterase reactivator
    • Tekes K, Hasan MY, Sheen R, Kuca K, Petroianu G, Ludanyi K, Kalasz H. 2006. High-performance liquid chromatographic determination of the plasma concentration of K-27, a novel oxime-type cholinesterase reactivator. J. Chromatogr. A 1122: 84-87.
    • (2006) J. Chromatogr. A , vol.1122 , pp. 84-87
    • Tekes, K.1    Hasan, M.Y.2    Sheen, R.3    Kuca, K.4    Petroianu, G.5    Ludanyi, K.6    Kalasz, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.