Efficacy of two new asymmetric bispyridinium oximes (K-27 and K-48) in rats exposed to diisopropylfluorophosphate: Comparison with pralidoxime, obidoxime, trimedoxime, methoxime, and HI-6 DFP and oximes in vivo

Toxicology Mechanisms and Methods

Volumn 19, Issue 4, 2009, Pages 327-333

  Lorke, D E ^a,b   Hasan, M Y ^a   Nurulain, S M ^a   Kua, K ^c   Schmitt, A ^d   Petroianu, G A ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNIVERSITY OF HAMBURG   (Germany)

^c UNIVERSITY OF DEFENCE   (Czech Republic)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Cox analysis; DFP; K oxime; Organophosphate; Oxime; Rat

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1 (4 HYDROXYIMINO METHYLPYRIDINIUM) 4 (4 CARBAMOYLPYRIDINIUM) BUTANE DIBROMIDE; 1 (4 HYDROXYIMINO METHYLPYRIDINIUM) 4 (4 CARBAMOYLPYRIDINIUM) PROPANE DIBROMIDE; ACETYLCHOLINESTERASE; BIS(PYRIDINIUM OXIME) DERIVATIVE; DYFLOS; K 27; K 48; METHOXIME; OBIDOXIME; OXIME DERIVATIVE; PRALIDOXIME; TRIMEDOXIME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIISOPROPYLFLUOROPHOSPHATE INTOXICATION; DRUG EFFICACY; IN VITRO STUDY; IN VIVO STUDY; INTOXICATION; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RAT; RISK FACTOR;

ANIMALS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; ISOFLUROPHATE; MALE; OBIDOXIME CHLORIDE; OXIMES; PRALIDOXIME COMPOUNDS; PYRIDINIUM COMPOUNDS; RATS; RATS, WISTAR; TRIMEDOXIME;

RATTUS;

EID: 70350503765     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510902798695     Document Type: Article

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