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Volumn 17, Issue 7, 2007, Pages 401-408

New K-oximes (K-27 and K-48) in comparison with obidoxime (LuH-6), HI-6, trimedoxime (TMB-4), and pralidoxime (2-PAM): Survival in rats exposed IP to the organophosphate paraoxon

Author keywords

Cholinesterase; K Oxime; Organophosphate; Oxime; Paraoxon; Rat

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1 (4 HYDROXYIMINOMETHYLPYRIDINIUM) 3 (4 CARBAMOYLPYRIDINIUM)PROPANE DIBROMIDE; 1 (4 HYDROXYIMINOMETHYLPYRIDINIUM) 4 (4 CARBAMOYLPYRIDINIUM)BUTANE DIBROMIDE; OBIDOXIME; OXIME DERIVATIVE; PARAOXON; PRALIDOXIME; TRIMEDOXIME; UNCLASSIFIED DRUG;

EID: 34548433962     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510601131362     Document Type: Article
Times cited : (24)

References (27)
  • 1
    • 85120200169 scopus 로고    scopus 로고
    • Pralidoxime rescues both muscarinic and nicotinic systems
    • Alston, T. A. 2005. Pralidoxime rescues both muscarinic and nicotinic systems. Anesth. Analg. 101:926-927.
    • (2005) Anesth. Analg , vol.101 , pp. 926-927
    • Alston, T.A.1
  • 2
    • 10044275708 scopus 로고    scopus 로고
    • Organophosphates/nerve agent poisoning: Mechanism of action, diagnosis, prophylaxis, and treatment
    • Bajgar, J. 2004. Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment. Adv. Clin. Chem. 38:151-216.
    • (2004) Adv. Clin. Chem , vol.38 , pp. 151-216
    • Bajgar, J.1
  • 3
    • 79952996175 scopus 로고    scopus 로고
    • Buckley, N., Eddleston, M., and Szinicz, L. 2005. Oximes for acute organophosphate pesticide poisoning. Cochrane Database Syst. Rev. 1:CD005085.
    • Buckley, N., Eddleston, M., and Szinicz, L. 2005. Oximes for acute organophosphate pesticide poisoning. Cochrane Database Syst. Rev. 1:CD005085.
  • 4
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox, D. R. 1972. Regression models and life tables. J.R. Statist. Soc. B 34:189-220.
    • (1972) J.R. Statist. Soc. B , vol.34 , pp. 189-220
    • Cox, D.R.1
  • 6
    • 0036107171 scopus 로고    scopus 로고
    • Oximes in acute organophosphorus pesticide poisoning: A systematic review of clinical trials
    • Eddleston, M., Szinicz, L., Eyer, P., and Buckley, N. 2002. Oximes in acute organophosphorus pesticide poisoning: a systematic review of clinical trials. QJM. 95:275-283.
    • (2002) QJM , vol.95 , pp. 275-283
    • Eddleston, M.1    Szinicz, L.2    Eyer, P.3    Buckley, N.4
  • 7
    • 34548444035 scopus 로고
    • US Patent: 3852294
    • Hagedorn, I. 1974. US Patent: 3852294.
    • (1974)
    • Hagedorn, I.1
  • 8
    • 0036447187 scopus 로고    scopus 로고
    • Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents
    • Kassa, J. 2002. Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents. J. Toxicol. Clin. Toxicol. 6:803-816.
    • (2002) J. Toxicol. Clin. Toxicol , vol.6 , pp. 803-816
    • Kassa, J.1
  • 9
    • 0037424754 scopus 로고    scopus 로고
    • Synthesis of a potential reactivator of acetylcholinesterase-1-(4- hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium)-propane dibromide
    • Kuča, K., Bielavský, J., Cabal, J., and Bielavska, M. 2003a. Synthesis of a potential reactivator of acetylcholinesterase-1-(4- hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium)-propane dibromide. Tetrahedron Lett. 44:3123-3125.
    • (2003) Tetrahedron Lett , vol.44 , pp. 3123-3125
    • Kuča, K.1    Bielavský, J.2    Cabal, J.3    Bielavska, M.4
  • 10
    • 17444446525 scopus 로고    scopus 로고
    • Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase
    • Kuča, K., Bielavský, J., Cabal, J., and Kassa, J. 2003b. Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase. Bioorg. Med. Chem. Lett. 13:3545-3547.
    • (2003) Bioorg. Med. Chem. Lett , vol.13 , pp. 3545-3547
    • Kuča, K.1    Bielavský, J.2    Cabal, J.3    Kassa, J.4
  • 11
    • 6344278709 scopus 로고    scopus 로고
    • Synthesis of bisquaternary symmetric bis (2-hydroxyiminomethylpyridinium) alkane dibromides and their reactivation of cyclosarin-inhibited acetyl- cholinesterase
    • Kuča, K., Cabal, J., Patočka, J., and Kassa, J. 2004. Synthesis of bisquaternary symmetric bis (2-hydroxyiminomethylpyridinium) alkane dibromides and their reactivation of cyclosarin-inhibited acetyl- cholinesterase. Lett. Org. Chem. 1:84-86.
    • (2004) Lett. Org. Chem , vol.1 , pp. 84-86
    • Kuča, K.1    Cabal, J.2    Patočka, J.3    Kassa, J.4
  • 12
    • 33646056667 scopus 로고    scopus 로고
    • Structural requirements for acetylcholinesterase reactivators
    • Kuča, K., Jun, D., and Musilek, K. 2006. Structural requirements for acetylcholinesterase reactivators. Mini Rev. Med. Chem. 6:269-277.
    • (2006) Mini Rev. Med. Chem , vol.6 , pp. 269-277
    • Kuča, K.1    Jun, D.2    Musilek, K.3
  • 13
    • 0000745252 scopus 로고
    • Recognized and possible effects of pesticides in humans
    • Hayes, W. J, and Laws, E. R, Eds, Academic Press, San Diego
    • Levine, R. 1991. Recognized and possible effects of pesticides in humans. In: Handbook of Pesticide Toxicology, General Principles, Vol. 1. Hayes, W. J., and Laws, E. R. (Eds.), Academic Press, San Diego, 275-360.
    • (1991) Handbook of Pesticide Toxicology, General Principles , vol.1 , pp. 275-360
    • Levine, R.1
  • 14
    • 59649105130 scopus 로고
    • Quaternary hydroxy- iminomethylpyridinium salts. The dischloride of bis-(4-hydroxyiminomethyl-1- pyridinium-methyl)-ether (lueh6), a new reactivator of acetylcholinesterase inhibited by organic phosphoric acid esters
    • Luettringhaus, A., and Hagedorn, I. 1964. Quaternary hydroxy- iminomethylpyridinium salts. The dischloride of bis-(4-hydroxyiminomethyl-1- pyridinium-methyl)-ether (lueh6), a new reactivator of acetylcholinesterase inhibited by organic phosphoric acid esters. Arzneimittelforschung 14:1-5.
    • (1964) Arzneimittelforschung , vol.14 , pp. 1-5
    • Luettringhaus, A.1    Hagedorn, I.2
  • 15
    • 33748778822 scopus 로고    scopus 로고
    • Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase
    • Nov 1;
    • Musilek, K., Holas, O., Kuka, K., Jun, D., Dohnal, V., and Dolezal, M. 2006. Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. Bioorg. Med. Chem. Lett. Nov 1; 16(21):5673-5676.
    • (2006) Bioorg. Med. Chem. Lett , vol.16 , Issue.21 , pp. 5673-5676
    • Musilek, K.1    Holas, O.2    Kuka, K.3    Jun, D.4    Dohnal, V.5    Dolezal, M.6
  • 16
    • 0015165303 scopus 로고
    • Cholinesterase inhibition by organophosphorus compounds, and its clinical effects
    • Namba, T. 1971. Cholinesterase inhibition by organophosphorus compounds, and its clinical effects. Bull. WHO 44:289-307.
    • (1971) Bull. WHO , vol.44 , pp. 289-307
    • Namba, T.1
  • 17
    • 0015042946 scopus 로고
    • Poisoning due to organophosphate insecticides: Acute and chronic manifestations
    • Namba, T., Nolte, C. T., Jackrel, J., and Grob, D. 1971. Poisoning due to organophosphate insecticides: acute and chronic manifestations. Am. J. Med. 50:457-492.
    • (1971) Am. J. Med , vol.50 , pp. 457-492
    • Namba, T.1    Nolte, C.T.2    Jackrel, J.3    Grob, D.4
  • 19
    • 31344478996 scopus 로고    scopus 로고
    • Oxime therapy and outcomes in human organophosphate poisoning: An evaluation using meta-analytic techniques
    • Peter, V., Moran, J. L., and Graham, P. 2006. Oxime therapy and outcomes in human organophosphate poisoning: An evaluation using meta-analytic techniques. Crit. Care Med. 34:502-510.
    • (2006) Crit. Care Med , vol.34 , pp. 502-510
    • Peter, V.1    Moran, J.L.2    Graham, P.3
  • 20
    • 0034890978 scopus 로고    scopus 로고
    • High-dose intravenous paraoxon exposure does not cause organophosphate induced delayed neuropathy (OPIDN) in mini pigs
    • Petroianu, G., Hardt, F., Toomes, M., Bergler, W., and Rüfer, R. 2001. High-dose intravenous paraoxon exposure does not cause organophosphate induced delayed neuropathy (OPIDN) in mini pigs. J. Appl. Toxicol 21:263-268.
    • (2001) J. Appl. Toxicol , vol.21 , pp. 263-268
    • Petroianu, G.1    Hardt, F.2    Toomes, M.3    Bergler, W.4    Rüfer, R.5
  • 21
    • 0031830032 scopus 로고    scopus 로고
    • Control of blood pressure, heart rate and haematocrit during high-dose intravenous paraoxon exposure in mini pigs
    • Petroianu, G., Toomes, L. M., Petroianu, A., Bergeler, W., and Rüfer, R. 1998. Control of blood pressure, heart rate and haematocrit during high-dose intravenous paraoxon exposure in mini pigs. J. Appl. Toxicol. 18:293-298.
    • (1998) J. Appl. Toxicol , vol.18 , pp. 293-298
    • Petroianu, G.1    Toomes, L.M.2    Petroianu, A.3    Bergeler, W.4    Rüfer, R.5
  • 22
    • 33646831462 scopus 로고    scopus 로고
    • Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: Survival in rats exposed to the organophosphate paraoxon
    • Petroianu, G. A., Nurulain, S. M., Nagelkerke, N., Al-Sultan, M. A., Kuca, K., and Kassa, J. 2006. Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: survival in rats exposed to the organophosphate paraoxon. J. Appl. Toxicol. 26:262-268.
    • (2006) J. Appl. Toxicol , vol.26 , pp. 262-268
    • Petroianu, G.A.1    Nurulain, S.M.2    Nagelkerke, N.3    Al-Sultan, M.A.4    Kuca, K.5    Kassa, J.6
  • 24
    • 27144437741 scopus 로고    scopus 로고
    • Anticholinesterase insecticides
    • Pesticide Toxicology and International Regulation , Marrs, T. C, and Ballantyne, B, Eds, John Wiley & Sons Ltd, Chichester
    • Thompson, C. M., and Richardson, R. J. 2004. Anticholinesterase insecticides. In: Pesticide Toxicology and International Regulation (Current Toxicology Series). Marrs, T. C., and Ballantyne, B. (Eds.). John Wiley & Sons Ltd, Chichester, 89-127.
    • (2004) Current Toxicology Series , pp. 89-127
    • Thompson, C.M.1    Richardson, R.J.2
  • 25
    • 2342435029 scopus 로고    scopus 로고
    • Nerve agents: A comprehensive review
    • Wiener, S. W., and Hoffman, R. S. 2004. Nerve agents: a comprehensive review. J. Intensive Care Med. 19:22-37.
    • (2004) J. Intensive Care Med , vol.19 , pp. 22-37
    • Wiener, S.W.1    Hoffman, R.S.2
  • 26
    • 19544368045 scopus 로고
    • A powerful reactivator of alkylphosphate
    • Wilson, I. B., and Ginsburg, S. 1955. A powerful reactivator of alkylphosphate. Biochim. Biophys. Acta. 18:168-170.
    • (1955) Biochim. Biophys. Acta , vol.18 , pp. 168-170
    • Wilson, I.B.1    Ginsburg, S.2
  • 27
    • 0001243211 scopus 로고
    • Die Wirkung organischer Phosphorsäureester bzw. Phosphorsäureesterauf versch
    • Zoch, E. 1971. Die Wirkung organischer Phosphorsäureester bzw. Phosphorsäureesterauf versch. Enzyme. Arzneim. Forschung 21:181-187.
    • (1971) Enzyme. Arzneim. Forschung , vol.21 , pp. 181-187
    • Zoch, E.1


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