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Volumn 2008, Issue , 2008, Pages

The PPAR-platelet connection: Modulators of inflammation and potential cardiovascular effects

Author keywords

[No Author keywords available]

Indexed keywords

CD40 LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 77954243510     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2008/328172     Document Type: Review
Times cited : (19)

References (214)
  • 1
    • 30444453441 scopus 로고    scopus 로고
    • International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis
    • D. L. Bhatt, P. G. Steg, E. M. Ohman, et al, "International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis," Journal of the American Medical Association, Vol. 295, no. 2, pp. 180-189, 2006.
    • (2006) Journal of the American Medical Association , vol.295 , Issue.2 , pp. 180-189
    • Bhatt, D.L.1    Steg, P.G.2    Ohman, E.M.3
  • 2
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • A. J. Lusis, "Atherosclerosis," Nature, Vol. 407, no. 6801, pp. 233-241, 2000.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 233-241
    • Lusis, A.J.1
  • 5
    • 33745897327 scopus 로고    scopus 로고
    • Platelets as a novel target for PPARγ ligands: Implications for inflammation, diabetes, and cardiovascular disease
    • D. M. Ray, S. L. Spinelli, J. J. O'Brien, N. Blumberg, and R. P. Phipps, "Platelets as a novel target for PPARγ ligands: implications for inflammation, diabetes, and cardiovascular disease," BioDrugs, Vol. 20, no. 4, pp. 231-241, 2006.
    • (2006) BioDrugs , vol.20 , Issue.4 , pp. 231-241
    • Ray, D.M.1    Spinelli, S.L.2    O'Brien, J.J.3    Blumberg, N.4    Phipps, R.P.5
  • 6
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • R. Ross, "Atherosclerosis - an inflammatory disease," The New England Journal of Medicine, Vol. 340, no. 2, pp. 115-126, 1999.
    • (1999) The New England Journal of Medicine , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 7
    • 0038297520 scopus 로고    scopus 로고
    • Platelets trigger a CD40-dependent inflammatory response in the microvas-culature of inflammatory bowel disease patients
    • S. Danese, C. de la Motte, A. Sturm, et al., "Platelets trigger a CD40-dependent inflammatory response in the microvas-culature of inflammatory bowel disease patients," Gastroenterology, Vol. 124, no. 5, pp. 1249-1264, 2003.
    • (2003) Gastroenterology , vol.124 , Issue.5 , pp. 1249-1264
    • Danese, S.1    De La Motte, C.2    Sturm, A.3
  • 8
    • 34249815515 scopus 로고    scopus 로고
    • A pilot study showing an association between platelet hyperactivity and the severity of peripheral arterial disease
    • T Smith, G. Dhunnoo, I. Mohan, and V. Charlton-Menys, "A pilot study showing an association between platelet hyperactivity and the severity of peripheral arterial disease," Platelets, Vol. 18, no. 4, pp. 245-248, 2007.
    • (2007) Platelets , vol.18 , Issue.4 , pp. 245-248
    • Smith, T.1    Dhunnoo, G.2    Mohan, I.3    Charlton-Menys, V.4
  • 9
    • 24944453206 scopus 로고    scopus 로고
    • The potential role of platelet microparticles in atherosclerosis
    • K. T. Tan and G. Y. H. Lip, "The potential role of platelet microparticles in atherosclerosis," Thrombosis and Haemostasis, Vol. 94, no. 3, pp. 488-492, 2005.
    • (2005) Thrombosis and Haemostasis , vol.94 , Issue.3 , pp. 488-492
    • Tan, K.T.1    Lip, G.Y.H.2
  • 11
    • 0027495262 scopus 로고
    • Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multi-infarct dementias
    • Y. J. Lee, W. Jy, L. L. Horstman, et al, "Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multi-infarct dementias," Thrombosis Research, Vol. 72, no. 4, pp. 295-304, 1993.
    • (1993) Thrombosis Research , vol.72 , Issue.4 , pp. 295-304
    • Lee, Y.J.1    Jy, W.2    Horstman, L.L.3
  • 12
    • 0037340351 scopus 로고    scopus 로고
    • Enzyme immunoassay detection of platelet-derived microparticles and RANTES in acute coronary syndrome
    • S. Nomura, S. Uehata, S. Saito, K. Osumi, Y. Ozeki, and Y. Kimura, "Enzyme immunoassay detection of platelet-derived microparticles and RANTES in acute coronary syndrome," Thrombosis and Haemostasis, Vol. 89, no. 3, pp. 506-512, 2003.
    • (2003) Thrombosis and Haemostasis , vol.89 , Issue.3 , pp. 506-512
    • Nomura, S.1    Uehata, S.2    Saito, S.3    Osumi, K.4    Ozeki, Y.5    Kimura, Y.6
  • 13
    • 0034543087 scopus 로고    scopus 로고
    • P-selectin expression, platelet aggregates, and platelet-derived microparticle formation are increased in peripheral arterial disease
    • F. Zeiger, S. Stephan, G. Hoheisel, D. Pfeiffer, C. Ruehlmann, and M. Koksch, "P-selectin expression, platelet aggregates, and platelet-derived microparticle formation are increased in peripheral arterial disease," Blood Coagulation and Fibrinolysis, Vol. 11, no. 8, pp. 723-728, 2000.
    • (2000) Blood Coagulation and Fibrinolysis , vol.11 , Issue.8 , pp. 723-728
    • Zeiger, F.1    Stephan, S.2    Hoheisel, G.3    Pfeiffer, D.4    Ruehlmann, C.5    Koksch, M.6
  • 14
    • 12144291702 scopus 로고    scopus 로고
    • Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions
    • J. A. Coppinger, G. Cagney, S. Toomey, et al, "Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions," Blood, Vol. 103, no. 6, pp. 2096-2104, 2004.
    • (2004) Blood , vol.103 , Issue.6 , pp. 2096-2104
    • Coppinger, J.A.1    Cagney, G.2    Toomey, S.3
  • 15
  • 16
    • 2642557064 scopus 로고    scopus 로고
    • Integration of proteomics and genomics in platelets: A profile of platelet proteins and platelet-specific genes
    • J. P. McRedmond, S. D. Park, D. F. Reilly, et al, "Integration of proteomics and genomics in platelets: a profile of platelet proteins and platelet-specific genes," Molecular & Cellular Proteomics, Vol. 3, no. 2, pp. 133-144, 2004.
    • (2004) Molecular & Cellular Proteomics , vol.3 , Issue.2 , pp. 133-144
    • McRedmond, J.P.1    Park, S.D.2    Reilly, D.F.3
  • 17
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • S. Kersten, B. Desvergne, and W. Wahli, "Roles of PPARs in health and disease," Nature, Vol. 405, no. 6785, pp. 421-424, 2000.
    • (2000) Nature , vol.405 , Issue.6785 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 18
    • 1642268085 scopus 로고    scopus 로고
    • Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor α in mice
    • H. Inoue, X.-F. Jiang, T. Katayama, S. Osada, K. Umesono, and S. Namura, "Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor α in mice," Neuroscience Letters, Vol. 352, no. 3, pp. 203-206, 2003.
    • (2003) Neuroscience Letters , vol.352 , Issue.3 , pp. 203-206
    • Inoue, H.1    Jiang, X.-F.2    Katayama, T.3    Osada, S.4    Umesono, K.5    Namura, S.6
  • 19
    • 34547584189 scopus 로고    scopus 로고
    • Thiazolidinediones and cardiovascular disease
    • "Thiazolidinediones and cardiovascular disease," The Medical Letter on Drugs and Therapeutics, Vol. 49, no. 1265, pp. 57-58, 2007.
    • (2007) The Medical Letter on Drugs and Therapeutics , vol.49 , Issue.1265 , pp. 57-58
  • 20
    • 31044443970 scopus 로고    scopus 로고
    • The biogenesis of platelets from megakaryocyte proplatelets
    • S. R. Patel, J. H. Hartwig, and J. E. Italiano Jr., "The biogenesis of platelets from megakaryocyte proplatelets," Journal of Clinical Investigation, Vol. 115, no. 12, pp. 3348-3354, 2005.
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.12 , pp. 3348-3354
    • Patel, S.R.1    Hartwig, J.H.2    Italiano, J.E.3
  • 21
    • 23744515307 scopus 로고    scopus 로고
    • Escaping the nuclear confines: Signal-dependent pre-mRNA splicing in anucleate platelets
    • M. M. Denis, N. D. Tolley, M. Bunting, et al, "Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets," Cell, Vol. 122, no. 3, pp. 379-391, 2005.
    • (2005) Cell , vol.122 , Issue.3 , pp. 379-391
    • Denis, M.M.1    Tolley, N.D.2    Bunting, M.3
  • 22
    • 0037443545 scopus 로고    scopus 로고
    • Transcript profiling of human platelets using microarray and serial analysis of gene expression
    • D. V. Gnatenko, J. J. Dunn, S. R. McCorkle, D. Weissmann, P. L. Perrotta, and W. F. Bahou, "Transcript profiling of human platelets using microarray and serial analysis of gene expression," Blood, Vol. 101, no. 6, pp. 2285-2293, 2003.
    • (2003) Blood , vol.101 , Issue.6 , pp. 2285-2293
    • Gnatenko, D.V.1    Dunn, J.J.2    McCorkle, S.R.3    Weissmann, D.4    Perrotta, P.L.5    Bahou, W.F.6
  • 25
    • 0035817627 scopus 로고    scopus 로고
    • Activated platelets mediate inflammatory signaling by regulated interleukin 1β synthesis
    • S. Lindemann, N. D. Tolley, D. A. Dixon, et al, "Activated platelets mediate inflammatory signaling by regulated interleukin 1β synthesis," Journal of Cell Biology, Vol. 154, no. 3, pp. 485-490, 2001.
    • (2001) Journal of Cell Biology , vol.154 , Issue.3 , pp. 485-490
    • Lindemann, S.1    Tolley, N.D.2    Dixon, D.A.3
  • 26
    • 10244249152 scopus 로고    scopus 로고
    • Platelets synthesize large amounts of active plasminogen activator inhibitor 1
    • H. Brogren, L. Karlsson, M. Andersson, L. Wang, D. Erlinge, and S. Jern, "Platelets synthesize large amounts of active plasminogen activator inhibitor 1," Blood, Vol. 104, no. 13, pp. 3943-3948, 2004.
    • (2004) Blood , vol.104 , Issue.13 , pp. 3943-3948
    • Brogren, H.1    Karlsson, L.2    Andersson, M.3    Wang, L.4    Erlinge, D.5    Jern, S.6
  • 27
    • 10744232582 scopus 로고    scopus 로고
    • Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs
    • M. Camera, M. Frigerio, V. Toschi, et al, "Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs," Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 23, no. 9, pp. 1690-1696, 2003.
    • (2003) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.23 , Issue.9 , pp. 1690-1696
    • Camera, M.1    Frigerio, M.2    Toschi, V.3
  • 28
    • 33750517555 scopus 로고    scopus 로고
    • Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenecity of human platelets
    • H. Schwertz, N. D. Tolley, J. M. Foulks, et al, "Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenecity of human platelets," Journal of Experimental Medicine, Vol. 203, no. 11, pp. 2433-2440, 2006.
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.11 , pp. 2433-2440
    • Schwertz, H.1    Tolley, N.D.2    Foulks, J.M.3
  • 29
    • 34249991214 scopus 로고    scopus 로고
    • Human platelets synthesize and express functional tissue factor
    • O. Panes, V. Matus, C. G. Sáez, T. Quiroga, J. Pereira, and D. Mezzano, "Human platelets synthesize and express functional tissue factor," Blood, Vol. 109, no. 12, pp. 5242-5250, 2007.
    • (2007) Blood , vol.109 , Issue.12 , pp. 5242-5250
    • Panes, O.1    Matus, V.2    Sáez, C.G.3    Quiroga, T.4    Pereira, J.5    Mezzano, D.6
  • 31
    • 0037421497 scopus 로고    scopus 로고
    • Vascular biology of atherosclerosis: Overview and state of the art
    • P. Libby, "Vascular biology of atherosclerosis: overview and state of the art," The American Journal of Cardiology, Vol. 91, no. 3, supplement 1, pp. 3-6, 2003.
    • (2003) The American Journal of Cardiology , vol.91 , Issue.3 , pp. 3-6
    • Libby, P.1
  • 32
    • 0344850187 scopus 로고    scopus 로고
    • Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes
    • P. Aukrust, F. Müller, T. Ueland, et al, "Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes," Circulation, Vol. 100, no. 6, pp. 614-620, 1999.
    • (1999) Circulation , vol.100 , Issue.6 , pp. 614-620
    • Aukrust, P.1    Müller, F.2    Ueland, T.3
  • 33
    • 0037162340 scopus 로고    scopus 로고
    • Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: Effects of statin therapy
    • F. Cipollone, A. Mezzetti, E. Porreca, et al, "Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: effects of statin therapy," Circulation, Vol. 106, no. 4, pp. 399-402, 2002.
    • (2002) Circulation , vol.106 , Issue.4 , pp. 399-402
    • Cipollone, F.1    Mezzetti, A.2    Porreca, E.3
  • 34
  • 35
    • 0035938914 scopus 로고    scopus 로고
    • Platelet derived CD154 (CD40 ligand) and febrile responses to transfusion
    • R. P. Phipps, J. Kaufman, and N. Blumberg, "Platelet derived CD154 (CD40 ligand) and febrile responses to transfusion," The Lancet, Vol. 357, no. 9273, pp. 2023-2024, 2001.
    • (2001) The Lancet , vol.357 , Issue.9273 , pp. 2023-2024
    • Phipps, R.P.1    Kaufman, J.2    Blumberg, N.3
  • 37
    • 34147112413 scopus 로고    scopus 로고
    • Release of biologically active CD154 during collection and storage of platelet concentrates prepared for transfusion
    • J. Kaufman, S. L. Spinelli, E. Schultz, N. Blumberg, and R. P. Phipps, "Release of biologically active CD154 during collection and storage of platelet concentrates prepared for transfusion," Journal of Thrombosis and Haemostasis, Vol. 5, no. 4, pp. 788-796, 2007.
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.4 , pp. 788-796
    • Kaufman, J.1    Spinelli, S.L.2    Schultz, E.3    Blumberg, N.4    Phipps, R.P.5
  • 38
    • 9144256042 scopus 로고    scopus 로고
    • Enhanced levels of CD154 (CD40 ligand) on platelets in patients with chronic heart failure
    • C. Stumpf, C. Lehner, S. Eskafi, et al, "Enhanced levels of CD154 (CD40 ligand) on platelets in patients with chronic heart failure," European Journal of Heart Failure, Vol. 5, no. 5, pp. 629-637, 2003.
    • (2003) European Journal of Heart Failure , vol.5 , Issue.5 , pp. 629-637
    • Stumpf, C.1    Lehner, C.2    Eskafi, S.3
  • 39
    • 0038580675 scopus 로고    scopus 로고
    • Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: A novel target of thiazolidinediones
    • N. Varo, D. Vicent, P. Libby, et al, "Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinediones," Circulation, Vol. 107, no. 21, pp. 2664-2669, 2003.
    • (2003) Circulation , vol.107 , Issue.21 , pp. 2664-2669
    • Varo, N.1    Vicent, D.2    Libby, P.3
  • 40
    • 0030152162 scopus 로고    scopus 로고
    • CD40 and its ligand in host defense
    • R. J. Noelle, "CD40 and its ligand in host defense," Immunity, Vol. 4, no. 5, pp. 415-419, 1996.
    • (1996) Immunity , vol.4 , Issue.5 , pp. 415-419
    • Noelle, R.J.1
  • 44
    • 12344303983 scopus 로고    scopus 로고
    • New horizons in the analysis of circulating cell-derived microparticles
    • L. L. Horstman, W. Jy, J. J. Jimenez, C. Bidot, and Y. S. Ahn, "New horizons in the analysis of circulating cell-derived microparticles," Keio Journal of Medicine, Vol. 53, no. 4, pp. 210-230, 2004.
    • (2004) Keio Journal of Medicine , vol.53 , Issue.4 , pp. 210-230
    • Horstman, L.L.1    Jy, W.2    Jimenez, J.J.3    Bidot, C.4    Ahn, Y.S.5
  • 45
    • 29144507363 scopus 로고    scopus 로고
    • Cell membrane microparticles in blood and blood products: Potentially pathogenic agents and diagnostic markers
    • J. Simak and M. P. Gelderman, "Cell membrane microparticles in blood and blood products: potentially pathogenic agents and diagnostic markers," Transfusion Medicine Reviews, Vol. 20, no. 1, pp. 1-26, 2006.
    • (2006) Transfusion Medicine Reviews , vol.20 , Issue.1 , pp. 1-26
    • Simak, J.1    Gelderman, M.P.2
  • 46
    • 0022258726 scopus 로고
    • Association of factor V activity with membranous vesicles released from human platelets: Requirement for platelet stimulation
    • A. P. Bode, H. Sandberg, F. A. Dombrose, and B. R. Lentz, "Association of factor V activity with membranous vesicles released from human platelets: requirement for platelet stimulation," Thrombosis Research, Vol. 39, no. 1, pp. 49-61, 1985.
    • (1985) Thrombosis Research , vol.39 , Issue.1 , pp. 49-61
    • Bode, A.P.1    Sandberg, H.2    Dombrose, F.A.3    Lentz, B.R.4
  • 47
    • 0030015094 scopus 로고    scopus 로고
    • Platelet-derived microparticles associate with fibrin during thrombosis
    • P. Siljander, O. Carpen, and R. Lassila, "Platelet-derived microparticles associate with fibrin during thrombosis," Blood, Vol. 87, no. 11, pp. 4651-4663, 1996.
    • (1996) Blood , vol.87 , Issue.11 , pp. 4651-4663
    • Siljander, P.1    Carpen, O.2    Lassila, R.3
  • 48
    • 0034802770 scopus 로고    scopus 로고
    • High-shear-stress-induced activation of platelets and microparticles enhances expression of cell adhesion molecules in THP-1 and endothelial cells
    • S. Nomura, N. N. Tandon, T. Nakamura, J. Cone, S. Fukuhara, and J. Kambayashi, "High-shear-stress-induced activation of platelets and microparticles enhances expression of cell adhesion molecules in THP-1 and endothelial cells," Atherosclerosis, Vol. 158, no. 2, pp. 277-287, 2001.
    • (2001) Atherosclerosis , vol.158 , Issue.2 , pp. 277-287
    • Nomura, S.1    Tandon, N.N.2    Nakamura, T.3    Cone, J.4    Fukuhara, S.5    Kambayashi, J.6
  • 50
    • 0032128299 scopus 로고    scopus 로고
    • Modulation of monocyte-endothelial cell interactions by platelet microparticles
    • O. P. Barry, D. Praticò, R. C. Savani, and G. A. FitzGerald, "Modulation of monocyte-endothelial cell interactions by platelet microparticles," Journal of Clinical Investigation, Vol. 102, no. 1, pp. 136-144, 1998.
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.1 , pp. 136-144
    • Barry, O.P.1    Praticò, D.2    Savani, R.C.3    FitzGerald, G.A.4
  • 51
    • 0036912752 scopus 로고    scopus 로고
    • Transfer of tissue factor from platelets to monocytes: Role of platelet-derived microvesicles and CD62P
    • T. Scholz, U. Temmler, S. Krause, S. Heptinstall, and W. Lösche, "Transfer of tissue factor from platelets to monocytes: role of platelet-derived microvesicles and CD62P," Thrombosis and Haemostasis, Vol. 88, no. 6, pp. 1033-1038, 2002.
    • (2002) Thrombosis and Haemostasis , vol.88 , Issue.6 , pp. 1033-1038
    • Scholz, T.1    Temmler, U.2    Krause, S.3    Heptinstall, S.4    Lösche, W.5
  • 53
    • 0037027467 scopus 로고    scopus 로고
    • Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus
    • M. Diamant, R. Nieuwland, R. F. Pablo, A. Sturk, J. W. A. Smit, and J. K. Radder, "Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus," Circulation, Vol. 106, no. 19, pp. 2442-2447, 2002.
    • (2002) Circulation , vol.106 , Issue.19 , pp. 2442-2447
    • Diamant, M.1    Nieuwland, R.2    Pablo, R.F.3    Sturk, A.4    Smit, J.W.A.5    Radder, J.K.6
  • 54
    • 0035892114 scopus 로고    scopus 로고
    • Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment
    • A. Janowska-Wieczorek, M. Majka, J. Kijowski, et al, "Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment," Blood, Vol. 98, no. 10, pp. 3143-3149, 2001.
    • (2001) Blood , vol.98 , Issue.10 , pp. 3143-3149
    • Janowska-Wieczorek, A.1    Majka, M.2    Kijowski, J.3
  • 55
    • 0034875893 scopus 로고    scopus 로고
    • PPARs in inflammation, atherosclerosis and thrombosis
    • H. Duez, J.-C. Fruchart, and B. Staels, "PPARs in inflammation, atherosclerosis and thrombosis," Journal of Cardiovascular Risk, Vol. 8, no. 4, pp. 187-194, 2001.
    • (2001) Journal of Cardiovascular Risk , vol.8 , Issue.4 , pp. 187-194
    • Duez, H.1    Fruchart, J.-C.2    Staels, B.3
  • 57
    • 0025932630 scopus 로고
    • Cloning of novel members of the steroid hormone receptor superfamily
    • I. Issemann and S. Green, "Cloning of novel members of the steroid hormone receptor superfamily," Journal of Steroid Biochemistry and Molecular Biology, Vol. 40, no. 1-3, pp. 263-269, 1991.
    • (1991) Journal of Steroid Biochemistry and Molecular Biology , vol.40 , Issue.1-3 , pp. 263-269
    • Issemann, I.1    Green, S.2
  • 58
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ in the adult rat
    • O. Braissant, F. Foufelle, C. Scotto, M. Dauça, and W. Wahli, "Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α, -β, and -γ in the adult rat," Endocrinology, Vol. 137, no. 1, pp. 354-366, 1996.
    • (1996) Endocrinology , vol.137 , Issue.1 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauça, M.4    Wahli, W.5
  • 59
    • 0035062387 scopus 로고    scopus 로고
    • The nuclear receptor PPAR γ is expressed by mouse T lymphocytes and PPAR γ agonists induce apoptosis
    • S. G. Harris and R. P. Phipps, "The nuclear receptor PPAR γ is expressed by mouse T lymphocytes and PPAR γ agonists induce apoptosis," European Journal of Immunology, Vol. 31, no. 4, pp. 1098-1105, 2001.
    • (2001) European Journal of Immunology , vol.31 , Issue.4 , pp. 1098-1105
    • Harris, S.G.1    Phipps, R.P.2
  • 60
    • 4644371751 scopus 로고    scopus 로고
    • Human multiple myeloma cells express peroxisome proliferator-activated receptor γ and undergo apoptosis upon exposure to PPARy ligands
    • D. M. Ray, S. H. Bernstein, and R. P. Phipps, "Human multiple myeloma cells express peroxisome proliferator-activated receptor γ and undergo apoptosis upon exposure to PPARy ligands," Clinical Immunology, Vol. 113, no. 2, pp. 203-213, 2004.
    • (2004) Clinical Immunology , vol.113 , Issue.2 , pp. 203-213
    • Ray, D.M.1    Bernstein, S.H.2    Phipps, R.P.3
  • 61
    • 0030747895 scopus 로고    scopus 로고
    • Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans: No alteration in adipose tissue of obese and NIDDM patients
    • D. Auboeuf, J. Rieusset, L. Fajas, et al, "Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans: no alteration in adipose tissue of obese and NIDDM patients," Diabetes, Vol. 46, no. 8, pp. 1319-1327, 1997.
    • (1997) Diabetes , vol.46 , Issue.8 , pp. 1319-1327
    • Auboeuf, D.1    Rieusset, J.2    Fajas, L.3
  • 62
    • 34548635236 scopus 로고    scopus 로고
    • Emerging roles of PPARδ in metabolism
    • U. Seedorf and J. Aberle, "Emerging roles of PPARδ in metabolism," Biochimica et Biophysica Acta, Vol. 1771, no. 9, pp. 1125-1131, 2007.
    • (2007) Biochimica et Biophysica Acta , vol.1771 , Issue.9 , pp. 1125-1131
    • Seedorf, U.1    Aberle, J.2
  • 63
    • 4444363344 scopus 로고    scopus 로고
    • Human bone marrow megakaryocytes and platelets express PPARy, and PPARy agonists blunt platelet release of CD40 ligand and thromboxanes
    • F. Akbiyik, D. M. Ray, K. F. Gettings, N. Blumberg, C. W. Francis, and R. P. Phipps, "Human bone marrow megakaryocytes and platelets express PPARy, and PPARy agonists blunt platelet release of CD40 ligand and thromboxanes," Blood, Vol. 104, no. 5, pp. 1361-1368, 2004.
    • (2004) Blood , vol.104 , Issue.5 , pp. 1361-1368
    • Akbiyik, F.1    Ray, D.M.2    Gettings, K.F.3    Blumberg, N.4    Francis, C.W.5    Phipps, R.P.6
  • 64
    • 33644883024 scopus 로고    scopus 로고
    • Role of nuclear receptor signaling in platelets: Antithrombotic effects of PPARβ
    • F. Y. Ali, S. J. Davidson, L. A. Moraes, et al, "Role of nuclear receptor signaling in platelets: antithrombotic effects of PPARβ," The FASEB Journal, Vol. 20, no. 2, pp. 326-328, 2006.
    • (2006) The FASEB Journal , vol.20 , Issue.2 , pp. 326-328
    • Ali, F.Y.1    Davidson, S.J.2    Moraes, L.A.3
  • 65
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • S. A. Kliewer, K. Umesono, D. J. Noonan, R. A. Heyman, and R. M. Evans, "Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors," Nature, Vol. 358, no. 6389, pp. 771-774, 1992.
    • (1992) Nature , vol.358 , Issue.6389 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 66
    • 23444431623 scopus 로고    scopus 로고
    • Retinoid X receptor heterodimers in the metabolic syndrome
    • A. I. Shulman and D. J. Mangelsdorf, "Retinoid X receptor heterodimers in the metabolic syndrome," The New England Journal of Medicine, Vol. 353, no. 6, pp. 604-615, 2005.
    • (2005) The New England Journal of Medicine , vol.353 , Issue.6 , pp. 604-615
    • Shulman, A.I.1    Mangelsdorf, D.J.2
  • 67
    • 3142510687 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis and diabetes mellitus
    • J. Plutzky, "Inflammation in atherosclerosis and diabetes mellitus," Reviews in Endocrine and Metabolic Disorders, Vol. 5, no. 3, pp. 255-259, 2004.
    • (2004) Reviews in Endocrine and Metabolic Disorders , vol.5 , Issue.3 , pp. 255-259
    • Plutzky, J.1
  • 68
    • 2442711384 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells
    • N. Marx, H. Duez, J.-C. Fruchart, and B. Staels, "Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells," Circulation Research, Vol. 94, no. 9, pp. 1168-1178, 2004.
    • (2004) Circulation Research , vol.94 , Issue.9 , pp. 1168-1178
    • Marx, N.1    Duez, H.2    Fruchart, J.-C.3    Staels, B.4
  • 69
    • 33745714392 scopus 로고    scopus 로고
    • PPARs and other nuclear receptors in inflammation
    • G. Rizzo and S. Fiorucci, "PPARs and other nuclear receptors in inflammation," Current Opinion in Pharmacology, Vol. 6, no. 4, pp. 421-427, 2006.
    • (2006) Current Opinion in Pharmacology , vol.6 , Issue.4 , pp. 421-427
    • Rizzo, G.1    Fiorucci, S.2
  • 70
    • 0027191040 scopus 로고
    • CDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
    • T. Sher, H. F. Yi, O. W. McBride, and F. J. Gonzalez, "cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor," Biochemistry, Vol. 32, no. 21, pp. 5598-5604, 1993.
    • (1993) Biochemistry , vol.32 , Issue.21 , pp. 5598-5604
    • Sher, T.1    Yi, H.F.2    McBride, O.W.3    Gonzalez, F.J.4
  • 72
    • 25444522187 scopus 로고    scopus 로고
    • Sensitivity to bleomycin-induced lung injury is not moderated by an antigen-limited T-cell repertoire
    • T. H. Thatcher, P. J. Sime, and R. K. Barth, "Sensitivity to bleomycin-induced lung injury is not moderated by an antigen-limited T-cell repertoire," Experimental Lung Research, Vol. 31, no. 7, pp. 685-700, 2005.
    • (2005) Experimental Lung Research , vol.31 , Issue.7 , pp. 685-700
    • Thatcher, T.H.1    Sime, P.J.2    Barth, R.K.3
  • 74
    • 0030325227 scopus 로고    scopus 로고
    • Regulation of triglyceride metabolism by PPARs: Fibrates andthi-azolidinediones have distinct effects
    • J. Auwerx, K. Schoonjans, J.-C. Fruchart, and B. Staels, "Regulation of triglyceride metabolism by PPARs: fibrates andthi-azolidinediones have distinct effects," Journal of atherosclerosis and thrombosis, Vol. 3, no. 2, pp. 81-89, 1996.
    • (1996) Journal of Atherosclerosis and Thrombosis , vol.3 , Issue.2 , pp. 81-89
    • Auwerx, J.1    Schoonjans, K.2    Fruchart, J.-C.3    Staels, B.4
  • 75
    • 33846623798 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets
    • J. D. Brown and J. Plutzky, "Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets," Circulation, Vol. 115, no. 4, pp. 518-533, 2007.
    • (2007) Circulation , vol.115 , Issue.4 , pp. 518-533
    • Brown, J.D.1    Plutzky, J.2
  • 76
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor S activates fat metabolism to prevent obesity
    • Y.-X. Wang, C.-H. Lee, S. Tiep, et al, "Peroxisome-proliferator-activated receptor S activates fat metabolism to prevent obesity," Cell, Vol. 113, no. 2, pp. 159-170, 2003.
    • (2003) Cell , vol.113 , Issue.2 , pp. 159-170
    • Wang, Y.-X.1    Lee, C.-H.2    Tiep, S.3
  • 77
    • 33644645013 scopus 로고    scopus 로고
    • PPARδ: A dagger in the heart of the metabolic syndrome
    • G. D. Barish, V. A. Narkar, and R. M. Evans, "PPARδ: a dagger in the heart of the metabolic syndrome," Journal of Clinical Investigation, Vol. 116, no. 3, pp. 590-597, 2006.
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.3 , pp. 590-597
    • Barish, G.D.1    Narkar, V.A.2    Evans, R.M.3
  • 78
    • 0142116239 scopus 로고    scopus 로고
    • Transcriptional repression of atherogenic inflammation: Modulation by PPARδ
    • C.-H. Lee, A. Chawla, N. Urbiztondo, D. Liao, W. A. Boisvert, and R. M. Evans, "Transcriptional repression of atherogenic inflammation: modulation by PPARδ," Science, Vol. 302, no. 5644, pp. 453-457, 2003.
    • (2003) Science , vol.302 , Issue.5644 , pp. 453-457
    • Lee, C.-H.1    Chawla, A.2    Urbiztondo, N.3    Liao, D.4    Boisvert, W.A.5    Evans, R.M.6
  • 79
    • 0036716140 scopus 로고    scopus 로고
    • Minireview: A novel pathway of prostacyclin signaling - Hanging out with nuclear receptors
    • H. Lim and S. K. Dey, "Minireview: a novel pathway of prostacyclin signaling - hanging out with nuclear receptors," Endocrinology, Vol. 143, no. 9, pp. 3207-3210, 2002.
    • (2002) Endocrinology , vol.143 , Issue.9 , pp. 3207-3210
    • Lim, H.1    Dey, S.K.2
  • 80
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and 5
    • B. M. Forman, J. Chen, and R. M. Evans, "Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and 5," Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, no. 9, pp. 4312-4317, 1997.
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.9 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 81
    • 0027364246 scopus 로고
    • Organic nitrates and compounds that increase intraplatelet cyclic guanosine monophosphate (cGMP) levels enhance the antiaggregating effects of the stable prostacyclin analogue iloprost
    • G. Anfossi, P. Massucco, E. Mularoni, F. Cavalot, L. Mattiello, and M. Trovati, "Organic nitrates and compounds that increase intraplatelet cyclic guanosine monophosphate (cGMP) levels enhance the antiaggregating effects of the stable prostacyclin analogue iloprost," Prostaglandins Leukotrienes and Essential Fatty Acids, Vol. 49, no. 5, pp. 839-845, 1993.
    • (1993) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.49 , Issue.5 , pp. 839-845
    • Anfossi, G.1    Massucco, P.2    Mularoni, E.3    Cavalot, F.4    Mattiello, L.5    Trovati, M.6
  • 82
    • 0027367670 scopus 로고
    • Interactions between nitric oxide and prostacyclin
    • R. J. Gryglewski, "Interactions between nitric oxide and prostacyclin," Seminars in Thrombosis and Hemostasis, Vol. 19, no. 2, pp. 158-166, 1993.
    • (1993) Seminars in Thrombosis and Hemostasis , vol.19 , Issue.2 , pp. 158-166
    • Gryglewski, R.J.1
  • 83
    • 0023878659 scopus 로고
    • Synergistic inhibition of platelet aggregation by endothelium-derived relaxing factor and prostacyclin
    • P. S. Macdonald, M. A. Read, and G. J. Dusting, "Synergistic inhibition of platelet aggregation by endothelium-derived relaxing factor and prostacyclin," Thrombosis Research, Vol. 49, no. 5, pp. 437-449, 1988.
    • (1988) Thrombosis Research , vol.49 , Issue.5 , pp. 437-449
    • Macdonald, P.S.1    Read, M.A.2    Dusting, G.J.3
  • 84
    • 0023446425 scopus 로고
    • The antiaggregating properties of vascular endothelium: Interactions between prostacyclin and nitric oxide
    • M. W. Radomski, R. M. Palmer, and S. Moncada, "The antiaggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide," British Journal of Pharmacology, Vol. 92, no. 3, pp. 639-646, 1987.
    • (1987) British Journal of Pharmacology , vol.92 , Issue.3 , pp. 639-646
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 85
    • 0027178139 scopus 로고
    • Synergistic platelet antiaggregatory effects of the adenylate cyclase activator iloprost and the guanylate cyclase activating agent SIN-1 in vivo
    • M. Spiecker, H. Darius, and J. Meyer, "Synergistic platelet antiaggregatory effects of the adenylate cyclase activator iloprost and the guanylate cyclase activating agent SIN-1 in vivo," Thrombosis Research, Vol. 70, no. 5, pp. 405-415, 1993.
    • (1993) Thrombosis Research , vol.70 , Issue.5 , pp. 405-415
    • Spiecker, M.1    Darius, H.2    Meyer, J.3
  • 86
    • 0024805212 scopus 로고
    • Interactions of iloprost and sodium nitroprusside on vascular smooth muscle and platelet aggregation
    • P. S. Lidbury, E. Antunes, G. de Nucci, and J. R. Vane, "Interactions of iloprost and sodium nitroprusside on vascular smooth muscle and platelet aggregation," British Journal of Pharmacology, Vol. 98, no. 4, pp. 1275-1280, 1989.
    • (1989) British Journal of Pharmacology , vol.98 , Issue.4 , pp. 1275-1280
    • Lidbury, P.S.1    Antunes, E.2    De Nucci, G.3    Vane, J.R.4
  • 87
    • 0026611494 scopus 로고
    • Synergism between PGE1-metabolites (13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation
    • R. Katzenschlager, K. Weiss, W. Rogatti, B. A. Peskar, and H. Sinzinger, "Synergism between PGE1-metabolites (13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-Dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation," Prostaglandins Leukotrienes and Essential Fatty Acids, Vol. 45, no. 3, pp. 207-210, 1992.
    • (1992) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.45 , Issue.3 , pp. 207-210
    • Katzenschlager, R.1    Weiss, K.2    Rogatti, W.3    Peskar, B.A.4    Sinzinger, H.5
  • 89
    • 32044471323 scopus 로고    scopus 로고
    • Role of prostacyclin versus peroxisome proliferator-activated receptor β receptors in prostacyclin sensing by lung fibroblasts
    • F. Y Ali, K. Egan, G. A. FitzGerald, et al, "Role of prostacyclin versus peroxisome proliferator-activated receptor β receptors in prostacyclin sensing by lung fibroblasts," American Journal of Respiratory Cell and Molecular Biology, Vol. 34, no. 2, pp. 242-246, 2006.
    • (2006) American Journal of Respiratory Cell and Molecular Biology , vol.34 , Issue.2 , pp. 242-246
    • Ali, F.Y.1    Egan, K.2    FitzGerald, G.A.3
  • 91
    • 0036245961 scopus 로고    scopus 로고
    • Human B lymphocytes and B lymphomas express PPAR-γ and are killed by PPAR-γ agonists
    • J. Padilla, E. Leung, and R. P. Phipps, "Human B lymphocytes and B lymphomas express PPAR-γ and are killed by PPAR-γ agonists," Clinical Immunology, Vol. 103, no. 1, pp. 22-33, 2002.
    • (2002) Clinical Immunology , vol.103 , Issue.1 , pp. 22-33
    • Padilla, J.1    Leung, E.2    Phipps, R.P.3
  • 92
    • 0347756655 scopus 로고    scopus 로고
    • Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shutting of PPAR-y and ReIA
    • D. Kelly, J. I. Campbell, T. P. King, et al, "Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shutting of PPAR-y and ReIA," Nature Immunology, Vol. 5, no. 1, pp. 104-112, 2004.
    • (2004) Nature Immunology , vol.5 , Issue.1 , pp. 104-112
    • Kelly, D.1    Campbell, J.I.2    King, T.P.3
  • 93
    • 0029102676 scopus 로고
    • Structural organization of mouse peroxisome proliferator-activated receptor γ (mPPARγ) gene: Alternative promoter use and different splicing yield two mPPARy isoforms
    • Y. Zhu, C. Qi, J. R. Korenberg, et al, "Structural organization of mouse peroxisome proliferator-activated receptor γ (mPPARγ) gene: alternative promoter use and different splicing yield two mPPARy isoforms," Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, no. 17, pp. 7921-7925, 1995.
    • (1995) Proceedings of the National Academy of Sciences of the United States of America , vol.92 , Issue.17 , pp. 7921-7925
    • Zhu, Y.1    Qi, C.2    Korenberg, J.R.3
  • 94
    • 0030835678 scopus 로고    scopus 로고
    • The organization, promoter analysis, and expression of the human PPARy gene
    • L. Fajas, D. Auboeuf, E. Raspé, et al, "The organization, promoter analysis, and expression of the human PPARy gene," Journal of Biological Chemistry, Vol. 272, no. 30, pp. 18779-18789, 1997.
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.30 , pp. 18779-18789
    • Fajas, L.1    Auboeuf, D.2    Raspé, E.3
  • 95
    • 0032560545 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
    • M. Ricote, J. Huang, L. Fajas, et al, "Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein," Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, no. 13, pp. 7614-7619, 1998.
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.13 , pp. 7614-7619
    • Ricote, M.1    Huang, J.2    Fajas, L.3
  • 96
    • 0032543415 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor γ (PPARγ) in rat aortic smooth muscle cells
    • K. Iijima, M. Yoshizumi, J. Ako, et al, "Expression of peroxisome proliferator-activated receptor γ (PPARγ) in rat aortic smooth muscle cells," Biochemical and Biophysical Research Communications, Vol. 247, no. 2, pp. 353-356, 1998.
    • (1998) Biochemical and Biophysical Research Communications , vol.247 , Issue.2 , pp. 353-356
    • Iijima, K.1    Yoshizumi, M.2    Ako, J.3
  • 97
    • 0036681640 scopus 로고    scopus 로고
    • Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor y
    • A. Nencioni, F. Grünebach, A. Zobywlaski, C. Denzlinger, W. Brugger, and P. Brossart, "Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor y," Journal of Immunology, Vol. 169, no. 3, pp. 1228-1235, 2002.
    • (2002) Journal of Immunology , vol.169 , Issue.3 , pp. 1228-1235
    • Nencioni, A.1    Grünebach, F.2    Zobywlaski, A.3    Denzlinger, C.4    Brugger, W.5    Brossart, P.6
  • 98
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-y is a negative regulator of macrophage activation
    • M. Ricote, A. C. Li, T. M. Willson, C. J. Kelly, and C. K. Glass, "The peroxisome proliferator-activated receptor-y is a negative regulator of macrophage activation," Nature, Vol. 391, no. 6662, pp. 79-82, 1998.
    • (1998) Nature , vol.391 , Issue.6662 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 99
    • 0347753697 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptors and cancers: Complex stories
    • L. Michalik, B. Desvergne, and W. Wahli, "Peroxisome-proliferator-activated receptors and cancers: complex stories," Nature Reviews Cancer, Vol. 4, no. 1, pp. 61-70, 2004.
    • (2004) Nature Reviews Cancer , vol.4 , Issue.1 , pp. 61-70
    • Michalik, L.1    Desvergne, B.2    Wahli, W.3
  • 101
    • 33847365733 scopus 로고    scopus 로고
    • PPARy1 attenuates cytosol to membrane translocation of PKCα to desensitize monocytes/macrophages
    • A. von Knethen, M. Soller, N. Tzieply, et al, "PPARy1 attenuates cytosol to membrane translocation of PKCα to desensitize monocytes/macrophages," Journal of Cell Biology, Vol. 176, no. 5, pp. 681-694, 2007.
    • (2007) Journal of Cell Biology , vol.176 , Issue.5 , pp. 681-694
    • Von Knethen, A.1    Soller, M.2    Tzieply, N.3
  • 102
    • 0034693323 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-y and nuclear factor-κB
    • S. W. Chung, B. Y Kang, S. H. Kim, et al, "Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-y and nuclear factor-κB," Journal of Biological Chemistry, Vol. 275, no. 42, pp. 32681-32687, 2000.
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.42 , pp. 32681-32687
    • Chung, S.W.1    Kang, B.Y.2    Kim, S.H.3
  • 103
    • 0032900439 scopus 로고    scopus 로고
    • New insights into the role of nuclear factor-κB, a ubiquitous transcription factor in the initiation of diseases
    • F. Chen, V. Castranova, X. Shi, and L. M. Demers, "New insights into the role of nuclear factor-κB, a ubiquitous transcription factor in the initiation of diseases," Clinical Chemistry, Vol. 45, no. 1, pp. 7-17, 1999.
    • (1999) Clinical Chemistry , vol.45 , Issue.1 , pp. 7-17
    • Chen, F.1    Castranova, V.2    Shi, X.3    Demers, L.M.4
  • 104
    • 34247330542 scopus 로고    scopus 로고
    • Nongenomic signaling of the retinoid X receptor through binding and in-hibiting Gq in human platelets
    • L. A. Moraes, K. E. Swales, J. A. Wray, et al, "Nongenomic signaling of the retinoid X receptor through binding and in-hibiting Gq in human platelets," Blood, Vol. 109, no. 9, pp. 3741-3744, 2007.
    • (2007) Blood , vol.109 , Issue.9 , pp. 3741-3744
    • Moraes, L.A.1    Swales, K.E.2    Wray, J.A.3
  • 105
    • 38349166623 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ and the retinoid X receptor transcription factors are released from activated human platelets and are shed in microparticles
    • D. M. Ray, S. L. Spinelli, S. J. Pollock, et al, "Peroxisome proliferator-activated receptor γ and the retinoid X receptor transcription factors are released from activated human platelets and are shed in microparticles," Thrombosis and Haemostasis, Vol. 101, 2008.
    • (2008) Thrombosis and Haemostasis , vol.101
    • Ray, D.M.1    Spinelli, S.L.2    Pollock, S.J.3
  • 106
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by per-oxisome proliferator-activated receptor-γ activators
    • V. Pasceri, H. D. Wu, J. T. Willerson, and E. T. H. Yeh, "Modulation of vascular inflammation in vitro and in vivo by per-oxisome proliferator-activated receptor-γ activators," Circulation, Vol. 101, no. 3, pp. 235-238, 2000.
    • (2000) Circulation , vol.101 , Issue.3 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3    Yeh, E.T.H.4
  • 107
    • 33747871378 scopus 로고    scopus 로고
    • The thiazolidine-dione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells
    • K. Goya, S. Sumitani, M. Otsuki, et al, "The thiazolidine-dione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells," Journal of Diabetes and its Complications, Vol. 20, no. 5, pp. 336-342, 2006.
    • (2006) Journal of Diabetes and its Complications , vol.20 , Issue.5 , pp. 336-342
    • Goya, K.1    Sumitani, S.2    Otsuki, M.3
  • 108
    • 33646940215 scopus 로고    scopus 로고
    • Pathophysiology of platelet resistance to anti-aggregating agents in insulin resistance and type 2 diabetes: Implications for anti-aggregating therapy
    • G. Anfossi and M. Trovati, "Pathophysiology of platelet resistance to anti-aggregating agents in insulin resistance and type 2 diabetes: implications for anti-aggregating therapy," Cardiovascular and Hematological Agents in Medicinal Chemistry, Vol. 4, no. 2, pp. 111-128, 2006.
    • (2006) Cardiovascular and Hematological Agents in Medicinal Chemistry , vol.4 , Issue.2 , pp. 111-128
    • Anfossi, G.1    Trovati, M.2
  • 109
    • 0142072232 scopus 로고    scopus 로고
    • The insulin resistance syndrome: Implications for thrombosis and cardiovascular disease
    • I. Juhan-Vague, P. E. Morange, and M.-C. Alessi, "The insulin resistance syndrome: implications for thrombosis and cardiovascular disease," Pathophysiology of Haemostasis and Thrombosis, Vol. 32, no. 5-6, pp. 269-273, 2002.
    • (2002) Pathophysiology of Haemostasis and Thrombosis , vol.32 , Issue.5-6 , pp. 269-273
    • Juhan-Vague, I.1    Morange, P.E.2    Alessi, M.-C.3
  • 110
    • 33745867367 scopus 로고    scopus 로고
    • Abnormalities of coagulation, platelet function, and fibrinolysis associated with syndromes of insulin resistance
    • D. J. Schneider, "Abnormalities of coagulation, platelet function, and fibrinolysis associated with syndromes of insulin resistance," Coronary Artery Disease, Vol. 16, no. 8, pp. 473-476, 2005.
    • (2005) Coronary Artery Disease , vol.16 , Issue.8 , pp. 473-476
    • Schneider, D.J.1
  • 111
    • 0036706856 scopus 로고    scopus 로고
    • Mechanisms involved in platelet hyperactivation and platelet-endothelium interrelationships in diabetes mellitus
    • M. Trovati and G. Anfossi, "Mechanisms involved in platelet hyperactivation and platelet-endothelium interrelationships in diabetes mellitus," Current Diabetes Reports, Vol. 2, no. 4, pp. 316-322, 2002.
    • (2002) Current Diabetes Reports , vol.2 , Issue.4 , pp. 316-322
    • Trovati, M.1    Anfossi, G.2
  • 112
    • 0036183388 scopus 로고    scopus 로고
    • Influence of insulin and of insulin resistance on platelet and vascular smooth muscle cell function
    • M. Trovati and G. Anfossi, "Influence of insulin and of insulin resistance on platelet and vascular smooth muscle cell function," Journal of Diabetes and Its Complications, Vol. 16, no. 1, pp. 35-40, 2002.
    • (2002) Journal of Diabetes and its Complications , vol.16 , Issue.1 , pp. 35-40
    • Trovati, M.1    Anfossi, G.2
  • 114
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • P. Libby, P. M. Ridker, and A. Maseri, "Inflammation and atherosclerosis," Circulation, Vol. 105, no. 9, pp. 1135-1143, 2002.
    • (2002) Circulation , vol.105 , Issue.9 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 117
    • 0037231665 scopus 로고    scopus 로고
    • Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E
    • Y. Huo, A. Schober, S. B. Forlow, et al, "Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E," Nature Medicine, Vol. 9, no. 1, pp. 61-67, 2002.
    • (2002) Nature Medicine , vol.9 , Issue.1 , pp. 61-67
    • Huo, Y.1    Schober, A.2    Forlow, S.B.3
  • 118
    • 33845676582 scopus 로고    scopus 로고
    • + progenitor cells into foam cells and endothelial cells
    • + progenitor cells into foam cells and endothelial cells," The FASEB Journal, Vol. 20, no. 14, pp. 2559-2561, 2006.
    • (2006) The FASEB Journal , vol.20 , Issue.14 , pp. 2559-2561
    • Daub, K.1    Langer, H.2    Seizer, P.3
  • 119
    • 0037037566 scopus 로고    scopus 로고
    • A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation
    • S. Massberg, K. Brand, S. Grüner, et al, "A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation," Journal of Experimental Medicine, Vol. 196, no. 7, pp. 887-896, 2002.
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.7 , pp. 887-896
    • Massberg, S.1    Brand, K.2    Grüner, S.3
  • 120
    • 24044440435 scopus 로고    scopus 로고
    • Platelet adhesion via glycoprotein IIb integrin is critical for athero-progression and focal cerebral ischemia: An in vivo study in mice lacking glycoprotein IIb
    • S. Massberg, K. Schürzinger, M. Lorenz, et al, "Platelet adhesion via glycoprotein IIb integrin is critical for athero-progression and focal cerebral ischemia: an in vivo study in mice lacking glycoprotein IIb," Circulation, Vol. 112, no. 8, pp. 1180-1188, 2005.
    • (2005) Circulation , vol.112 , Issue.8 , pp. 1180-1188
    • Massberg, S.1    Schürzinger, K.2    Lorenz, M.3
  • 122
    • 0030752615 scopus 로고    scopus 로고
    • 3) mediates platelet adhesion to the luminal aspect of endothelial cells: Implications for reperfusion in acute myocardial infarction
    • 3) mediates platelet adhesion to the luminal aspect of endothelial cells: implications for reperfusion in acute myocardial infarction," Circulation, Vol. 96, no. 6, pp. 1809-1818, 1997.
    • (1997) Circulation , vol.96 , Issue.6 , pp. 1809-1818
    • Gawaz, M.1    Neumann, F.-J.2    Dickfeld, T.3
  • 123
    • 0030053912 scopus 로고    scopus 로고
    • Platelet function in acute myocardial infarction treated with direct angioplasty
    • M. Gawaz, F.-J. Neumann, I. Ott, A. Schiessler, and A. Schömig, "Platelet function in acute myocardial infarction treated with direct angioplasty," Circulation, Vol. 93, no. 2, pp. 229-237, 1996.
    • (1996) Circulation , vol.93 , Issue.2 , pp. 229-237
    • Gawaz, M.1    Neumann, F.-J.2    Ott, I.3    Schiessler, A.4    Schömig, A.5
  • 124
    • 33644867007 scopus 로고    scopus 로고
    • Adherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitro
    • H. Langer, A. E. May, K. Daub, et al, "Adherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitro," Circulation Research, Vol. 98, no. 2, pp. e2-e10, 2006.
    • (2006) Circulation Research , vol.98 , Issue.2 , pp. e2-e10
    • Langer, H.1    May, A.E.2    Daub, K.3
  • 125
    • 1442350428 scopus 로고    scopus 로고
    • Effect of nonsteroidal anti-inflammatory drugs on amyloid-β formation and macrophage activation after platelet phagocytosis
    • D. M. Jans, W. Martinet, M. Fillet, et al, "Effect of nonsteroidal anti-inflammatory drugs on amyloid-β formation and macrophage activation after platelet phagocytosis," Journal of Cardiovascular Pharmacology, Vol. 43, no. 3, pp. 462-470, 2004.
    • (2004) Journal of Cardiovascular Pharmacology , vol.43 , Issue.3 , pp. 462-470
    • Jans, D.M.1    Martinet, W.2    Fillet, M.3
  • 126
    • 0037076799 scopus 로고    scopus 로고
    • Platelet phagocytosis and processing of β-amyloid precursor protein as a mechanism of macrophage activation in atherosclerosis
    • G. R. Y. De Meyer, D. M. M. De Cleen, S. Cooper, et al., "Platelet phagocytosis and processing of β-amyloid precursor protein as a mechanism of macrophage activation in atherosclerosis," Circulation Research, Vol. 90, no. 11, pp. 1197-1204, 2002.
    • (2002) Circulation Research , vol.90 , Issue.11 , pp. 1197-1204
    • De Meyer, G.R.Y.1    De Cleen, D.M.M.2    Cooper, S.3
  • 127
    • 0037458650 scopus 로고    scopus 로고
    • Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cells
    • T. Nassar, B. S. Sachais, S. Akkawi, et al, "Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cells," Journal of Biological Chemistry, Vol. 278, no. 8, pp. 6187-6193, 2003.
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.8 , pp. 6187-6193
    • Nassar, T.1    Sachais, B.S.2    Akkawi, S.3
  • 128
    • 0033990516 scopus 로고    scopus 로고
    • Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesis
    • M. Gawaz, K. Brand, T. Dickfeld, et al, "Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesis," Atherosclerosis, Vol. 148, no. 1, pp. 75-85, 2000.
    • (2000) Atherosclerosis , vol.148 , Issue.1 , pp. 75-85
    • Gawaz, M.1    Brand, K.2    Dickfeld, T.3
  • 129
    • 0035799376 scopus 로고    scopus 로고
    • RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium
    • P. von Hundelshausen, K. S. Weber, Y. Huo, et al, "RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium," Circulation, Vol. 103, no. 13, pp. 1772-1777, 2001.
    • (2001) Circulation , vol.103 , Issue.13 , pp. 1772-1777
    • Von Hundelshausen, P.1    Weber, K.S.2    Huo, Y.3
  • 130
    • 0032744218 scopus 로고    scopus 로고
    • Differential regulation of platelet aggregation by matrix metalloproteinases-9 and -2
    • C. Fernandez-Patron, M. A. Martinez-Cuesta, E. Salas, et al, "Differential regulation of platelet aggregation by matrix metalloproteinases-9 and -2," Thrombosis and Haemostasis, Vol. 82, no. 6, pp. 1730-1735, 1999.
    • (1999) Thrombosis and Haemostasis , vol.82 , Issue.6 , pp. 1730-1735
    • Fernandez-Patron, C.1    Martinez-Cuesta, M.A.2    Salas, E.3
  • 131
    • 0030946445 scopus 로고    scopus 로고
    • Release of gelatinase A during platelet activation mediates aggregation
    • G. Sawicki, E. Salas, J. Murat, H. Miszta-Lane, and M. W. Radomski, "Release of gelatinase A during platelet activation mediates aggregation," Nature, Vol. 386, no. 6625, pp. 616-619, 1997.
    • (1997) Nature , vol.386 , Issue.6625 , pp. 616-619
    • Sawicki, G.1    Salas, E.2    Murat, J.3    Miszta-Lane, H.4    Radomski, M.W.5
  • 132
    • 0037109144 scopus 로고    scopus 로고
    • 3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells
    • 3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells," Circulation, Vol. 106, no. 16, pp. 2111-2117, 2002.
    • (2002) Circulation , vol.106 , Issue.16 , pp. 2111-2117
    • May, A.E.1    Kälsch, T.2    Massberg, S.3    Herouy, Y.4    Schmidt, R.5    Gawaz, M.6
  • 133
  • 134
    • 0035860838 scopus 로고    scopus 로고
    • Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and platelets
    • S. W. Galt, S. Lindemann, D. Medd, et al, "Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and platelets," Circulation Research, Vol. 89, no. 6, pp. 509-516, 2001.
    • (2001) Circulation Research , vol.89 , Issue.6 , pp. 509-516
    • Galt, S.W.1    Lindemann, S.2    Medd, D.3
  • 135
    • 18144418144 scopus 로고    scopus 로고
    • Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels
    • N. A. Turner, D. J. O'Regan, S. G. Ball, and K. E. Porter, "Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels," The FASEB Journal, Vol. 19, no. 7, pp. 804-806, 2005.
    • (2005) The FASEB Journal , vol.19 , Issue.7 , pp. 804-806
    • Turner, N.A.1    O'Regan, D.J.2    Ball, S.G.3    Porter, K.E.4
  • 136
    • 0034978984 scopus 로고    scopus 로고
    • Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranyl-geranylation
    • B. Wong, W. C. Lumma, A. M. Smith, J. T. Sisko, S. D. Wright, and T.-Q. Cai, "Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranyl-geranylation," Journal of Leukocyte Biology, Vol. 69, no. 6, pp. 959-962, 2001.
    • (2001) Journal of Leukocyte Biology , vol.69 , Issue.6 , pp. 959-962
    • Wong, B.1    Lumma, W.C.2    Smith, A.M.3    Sisko, J.T.4    Wright, S.D.5    Cai, T.-Q.6
  • 137
    • 33744511921 scopus 로고    scopus 로고
    • Profound resolution of early atherosclerosis with conjugated linoleic acid
    • S. Toomey, B. Harhen, H. M. Roche, D. Fitzgerald, and O. Belton, "Profound resolution of early atherosclerosis with conjugated linoleic acid," Atherosclerosis, Vol. 187, no. 1, pp. 40-49, 2006.
    • (2006) Atherosclerosis , vol.187 , Issue.1 , pp. 40-49
    • Toomey, S.1    Harhen, B.2    Roche, H.M.3    Fitzgerald, D.4    Belton, O.5
  • 138
    • 85047693466 scopus 로고    scopus 로고
    • Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ
    • A. C. Li, C. J. Binder, A. Gutierrez, et al, "Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ," Journal of Clinical Investigation, Vol. 114, no. 11, pp. 1564-1576, 2004.
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.11 , pp. 1564-1576
    • Li, A.C.1    Binder, C.J.2    Gutierrez, A.3
  • 139
    • 0035097590 scopus 로고    scopus 로고
    • Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: Pleiotropic effects on CD36 expression and HDL
    • Z. Chen, S. Ishibashi, S. Perrey, et al, "Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL," Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 21, no. 3, pp. 372-377, 2001.
    • (2001) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.21 , Issue.3 , pp. 372-377
    • Chen, Z.1    Ishibashi, S.2    Perrey, S.3
  • 140
    • 0033864582 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
    • A. C. Li, K. K. Brown, M. J. Silvestre, T. M. Willson, W. Palinski, and C. K. Glass, "Peroxisome proliferator-activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice," Journal of Clinical Investigation, Vol. 106, no. 4, pp. 523-531, 2000.
    • (2000) Journal of Clinical Investigation , vol.106 , Issue.4 , pp. 523-531
    • Li, A.C.1    Brown, K.K.2    Silvestre, M.J.3    Willson, T.M.4    Palinski, W.5    Glass, C.K.6
  • 141
    • 2442425421 scopus 로고    scopus 로고
    • Rosiglitazone, alig-and of the peroxisome proliferator-activated receptor-γ, reduces acute pancreatitis induced by cerulein
    • S. Cuzzocrea, B. Pisano, L. Dugo, et al, "Rosiglitazone, alig-and of the peroxisome proliferator-activated receptor-γ, reduces acute pancreatitis induced by cerulein," Intensive Care Medicine, Vol. 30, no. 5, pp. 951-956, 2004.
    • (2004) Intensive Care Medicine , vol.30 , Issue.5 , pp. 951-956
    • Cuzzocrea, S.1    Pisano, B.2    Dugo, L.3
  • 142
    • 0034614270 scopus 로고    scopus 로고
    • Activation of PPARα or γ reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells
    • H. Shu, B. Wong, G. Zhou, et al, "Activation of PPARα or γ reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells," Biochemical and Biophysical Research Communications, Vol. 267, no. 1, pp. 345-349, 2000.
    • (2000) Biochemical and Biophysical Research Communications , vol.267 , Issue.1 , pp. 345-349
    • Shu, H.1    Wong, B.2    Zhou, G.3
  • 143
    • 3042811373 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-y agonist rosiglitazone reduces circulating platelet activity in patients without diabetes mellitus who have coronary artery disease
    • J. S. Sidhu, D. Cowan, J. A. Tooze, and J.-C. Kaski, "Peroxisome proliferator-activated receptor-y agonist rosiglitazone reduces circulating platelet activity in patients without diabetes mellitus who have coronary artery disease," American Heart Journal, Vol. 147, no. 6, pp. 1032-1037, 2004.
    • (2004) American Heart Journal , vol.147 , Issue.6 , pp. 1032-1037
    • Sidhu, J.S.1    Cowan, D.2    Tooze, J.A.3    Kaski, J.-C.4
  • 144
    • 33646569668 scopus 로고    scopus 로고
    • Effects of rosiglitazone on lipids, adipokines, and inflammatory markers in nondiabetic patients with low high-density lipoprotein cholesterol and metabolic syndrome
    • F. F. Samaha, P. O. Szapary, N. Iqbal, et al, "Effects of rosiglitazone on lipids, adipokines, and inflammatory markers in nondiabetic patients with low high-density lipoprotein cholesterol and metabolic syndrome," Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 26, no. 3, pp. 624-630, 2006.
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.3 , pp. 624-630
    • Samaha, F.F.1    Szapary, P.O.2    Iqbal, N.3
  • 145
    • 0034685589 scopus 로고    scopus 로고
    • Activation of PPARδ alters lipid metabolism in db/db mice
    • M. D. Leibowitz, C. Fiévet, N. Hennuyer, et al, "Activation of PPARδ alters lipid metabolism in db/db mice," FEBS Letters, Vol. 473, no. 3, pp. 333-336, 2000.
    • (2000) FEBS Letters , vol.473 , Issue.3 , pp. 333-336
    • Leibowitz, M.D.1    Fiévet, C.2    Hennuyer, N.3
  • 146
    • 22344449773 scopus 로고    scopus 로고
    • Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1
    • J. N. van der Veen, J. K. Kruit, R. Havinga, et al., "Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1," Journal of Lipid Research, Vol. 46, no. 3, pp. 526-534, 2005.
    • (2005) Journal of Lipid Research , vol.46 , Issue.3 , pp. 526-534
    • Van Der Veen, J.N.1    Kruit, J.K.2    Havinga, R.3
  • 147
    • 0021844957 scopus 로고
    • Fibrin formation and platelet aggregation in patients with severe coronary artery disease: Relationship with the degree of myocardial ischemia
    • A. Gallino, A. Haeberli, H. R. Baur, and P. W. Straub, "Fibrin formation and platelet aggregation in patients with severe coronary artery disease: relationship with the degree of myocardial ischemia," Circulation, Vol. 72, no. 1, pp. 27-30, 1985.
    • (1985) Circulation , vol.72 , Issue.1 , pp. 27-30
    • Gallino, A.1    Haeberli, A.2    Baur, H.R.3    Straub, P.W.4
  • 149
    • 0031685956 scopus 로고    scopus 로고
    • Differential effect of the antidiabetic thiazolidinediones troglitazone and pioglitazone on human platelet aggregation mechanism
    • T. Ishizuka, S. Itaya, H. Wada, et al, "Differential effect of the antidiabetic thiazolidinediones troglitazone and pioglitazone on human platelet aggregation mechanism," Diabetes, Vol. 47, no. 9, pp. 1494-1500, 1998.
    • (1998) Diabetes , vol.47 , Issue.9 , pp. 1494-1500
    • Ishizuka, T.1    Itaya, S.2    Wada, H.3
  • 150
    • 1242294387 scopus 로고    scopus 로고
    • A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and akt-dependent pathway and leads to endothelial-dependent vasorelaxation
    • M. Lorenz, S. Wessler, E. Follmann, et al, "A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation," Journal of Biological Chemistry, Vol. 279, no. 7, pp. 6190-6195, 2004.
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 6190-6195
    • Lorenz, M.1    Wessler, S.2    Follmann, E.3
  • 151
    • 13844272374 scopus 로고    scopus 로고
    • The effects of PPAR-γ lig-and pioglitazone on platelet aggregation and arterial thrombus formation
    • D. Li, K. Chen, N. Sinha, et al, "The effects of PPAR-γ lig-and pioglitazone on platelet aggregation and arterial thrombus formation," Cardiovascular Research, Vol. 65, no. 4, pp. 907-912, 2005.
    • (2005) Cardiovascular Research , vol.65 , Issue.4 , pp. 907-912
    • Li, D.1    Chen, K.2    Sinha, N.3
  • 152
    • 0037176138 scopus 로고    scopus 로고
    • Thrombomodulin expression by THP-1 but not by vascular endothelial cells is upregulated by pioglitazone
    • H. Kanehara, G. Tohda, K. Oida, J. Suzuki, H. Ishii, and I. Miyamori, "Thrombomodulin expression by THP-1 but not by vascular endothelial cells is upregulated by pioglitazone," Thrombosis Research, Vol. 108, no. 4, pp. 227-234, 2002.
    • (2002) Thrombosis Research , vol.108 , Issue.4 , pp. 227-234
    • Kanehara, H.1    Tohda, G.2    Oida, K.3    Suzuki, J.4    Ishii, H.5    Miyamori, I.6
  • 153
    • 0037231474 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ ligands increase release of nitric oxide from endothelial cells
    • D. S. Calnek, L. Mazzella, S. Roser, J. Roman, and C. M. Hart, "Peroxisome proliferator-activated receptor γ ligands increase release of nitric oxide from endothelial cells," Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 23, no. 1, pp. 52-57, 2003.
    • (2003) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.23 , Issue.1 , pp. 52-57
    • Calnek, D.S.1    Mazzella, L.2    Roser, S.3    Roman, J.4    Hart, C.M.5
  • 154
    • 1542652475 scopus 로고    scopus 로고
    • Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: Evidence for involvement of peroxisome proliferator-activated receptor (PPAR) γ-dependent and PPARγ-independent signaling pathways
    • D.-H. Cho, Y. J. Choi, S. A. Jo, and I. Jo, "Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: evidence for involvement of peroxisome proliferator-activated receptor (PPAR) γ-dependent and PPARγ-independent signaling pathways," Journal of Biological Chemistry, Vol. 279, no. 4, pp. 2499-2506, 2004.
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.4 , pp. 2499-2506
    • Cho, D.-H.1    Choi, Y.J.2    Jo, S.A.3    Jo, I.4
  • 155
    • 0034730794 scopus 로고    scopus 로고
    • Peroxi-some proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-α expression in neonatal rat cardiac myocytes
    • H. Takano, T. Nagai, M. Asakawa, et al, "Peroxi-some proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-α expression in neonatal rat cardiac myocytes," Circulation Research, Vol. 87, no. 7, pp. 596-602, 2000.
    • (2000) Circulation Research , vol.87 , Issue.7 , pp. 596-602
    • Takano, H.1    Nagai, T.2    Asakawa, M.3
  • 156
    • 0035923566 scopus 로고    scopus 로고
    • In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone
    • T.-L. Yue, J. Chen, W. Bao, et al, "In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone," Circulation, Vol. 104, no. 21, pp. 2588-2594, 2001.
    • (2001) Circulation , vol.104 , Issue.21 , pp. 2588-2594
    • Yue, T.-L.1    Chen, J.2    Bao, W.3
  • 157
    • 0032869566 scopus 로고    scopus 로고
    • The role of neutrophils in myocardial ischemia-reperfusion injury
    • J. E. Jordan, Z.-Q. Zhao, and J. Vinten-Johansen, "The role of neutrophils in myocardial ischemia-reperfusion injury," Cardiovascular Research, Vol. 43, no. 4, pp. 860-878, 1999.
    • (1999) Cardiovascular Research , vol.43 , Issue.4 , pp. 860-878
    • Jordan, J.E.1    Zhao, Z.-Q.2    Vinten-Johansen, J.3
  • 158
    • 0032737858 scopus 로고    scopus 로고
    • The per-oxisome proliferator-activated receptorγ (PPARγ) as a regulator of monocyte/macrophage function
    • M. Ricote, J. T. Huang, J. S. Welch, and C. K. Glass, "The per-oxisome proliferator-activated receptorγ (PPARγ) as a regulator of monocyte/macrophage function," Journal of Leukocyte Biology, Vol. 66, no. 5, pp. 733-739, 1999.
    • (1999) Journal of Leukocyte Biology , vol.66 , Issue.5 , pp. 733-739
    • Ricote, M.1    Huang, J.T.2    Welch, J.S.3    Glass, C.K.4
  • 159
    • 0035919661 scopus 로고    scopus 로고
    • Resveratrol reduction of infarct size in long-evans rats subjected to focal cerebral ischemia
    • S.S. Huang, M. C. Tsai, C. L. Chih, L.M. Hung, and S. K. Tsai, "Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia," Life Sciences, Vol. 69, no. 9, pp. 1057-1065, 2001.
    • (2001) Life Sciences , vol.69 , Issue.9 , pp. 1057-1065
    • Huang, S.S.1    Tsai, M.C.2    Chih, C.L.3    Hung, L.M.4    Tsai, S.K.5
  • 160
    • 0037272881 scopus 로고    scopus 로고
    • Therapeutic potential of peroxisome proliferator-activated receptor agonists for neurological disease
    • D. L. Feinstein, "Therapeutic potential of peroxisome proliferator-activated receptor agonists for neurological disease," Diabetes Technology & Therapeutics, Vol. 5, no. 1, pp. 67-73, 2003.
    • (2003) Diabetes Technology & Therapeutics , vol.5 , Issue.1 , pp. 67-73
    • Feinstein, D.L.1
  • 161
    • 34147182536 scopus 로고    scopus 로고
    • PPAR: A new pharmacological target for neuroprotection in stroke and neurode-generative diseases
    • R. Bordet, T. Ouk, O. Petrault, et al, "PPAR: a new pharmacological target for neuroprotection in stroke and neurode-generative diseases," Biochemical Society Transactions, Vol. 34, part 6, pp. 1341-1346, 2006.
    • (2006) Biochemical Society Transactions , vol.34 , pp. 1341-1346
    • Bordet, R.1    Ouk, T.2    Petrault, O.3
  • 162
    • 0031657607 scopus 로고    scopus 로고
    • Relationship between obesity and the increased risk of major complications in non-insulin-dependent diabetes mellitus
    • S. Rios, "Relationship between obesity and the increased risk of major complications in non-insulin-dependent diabetes mellitus," European Journal of Clinical Investigation, Vol. 28, supplement 2, pp. 14-18, 1998.
    • (1998) European Journal of Clinical Investigation , vol.28 , pp. 14-18
    • Rios, S.1
  • 163
    • 0024210824 scopus 로고
    • Mediators produced by the endothelial cell
    • R. J. Gryglewski, R. M. Botting, and J. R. Vane, "Mediators produced by the endothelial cell," Hypertension, Vol. 12, no. 6, pp. 530-548, 1988.
    • (1988) Hypertension , vol.12 , Issue.6 , pp. 530-548
    • Gryglewski, R.J.1    Botting, R.M.2    Vane, J.R.3
  • 164
    • 0031985026 scopus 로고    scopus 로고
    • Platelet resistance to nitrates in obesity and obese NIDDM, and normal platelet sensitivity to both insulin and nitrates in lean NIDDM
    • G. Anfossi, E. M. Mularoni, S. Burzacca, et al, "Platelet resistance to nitrates in obesity and obese NIDDM, and normal platelet sensitivity to both insulin and nitrates in lean NIDDM," Diabetes Care, Vol. 21, no. 1, pp. 121-126, 1998.
    • (1998) Diabetes Care , vol.21 , Issue.1 , pp. 121-126
    • Anfossi, G.1    Mularoni, E.M.2    Burzacca, S.3
  • 165
    • 3943106073 scopus 로고    scopus 로고
    • Impaired synthesis and action of antiaggregating cyclic nucleotides in platelets from obese subjects: Possible role in platelet hyperactivation in obesity
    • G. Anfossi, I. Russo, P. Massucco, et al, "Impaired synthesis and action of antiaggregating cyclic nucleotides in platelets from obese subjects: possible role in platelet hyperactivation in obesity," European Journal of Clinical Investigation, Vol. 34, no. 7, pp. 482-489, 2004.
    • (2004) European Journal of Clinical Investigation , vol.34 , Issue.7 , pp. 482-489
    • Anfossi, G.1    Russo, I.2    Massucco, P.3
  • 166
    • 0021043104 scopus 로고
    • Decreased sensitivity of platelets to prostacyclin in patients with diabetes mellitus
    • T. Akai, K. Naka, K. Okuda, T. Takemura, and S. Fujii, "Decreased sensitivity of platelets to prostacyclin in patients with diabetes mellitus," Hormone and Metabolic Research, Vol. 15, no. 11, pp. 523-526, 1983.
    • (1983) Hormone and Metabolic Research , vol.15 , Issue.11 , pp. 523-526
    • Akai, T.1    Naka, K.2    Okuda, K.3    Takemura, T.4    Fujii, S.5
  • 167
    • 0024202215 scopus 로고
    • The platelet insulin receptor: Detection, partial characterizaztion, and search for a function
    • C. Falcon, G. Pfliegler, H. Deckmyn, and J. Vermylen, "The platelet insulin receptor: detection, partial characterizaztion, and search for a function," Biochemical and Biophysical Research Communications, Vol. 157, no. 3, pp. 1190-1196, 1988.
    • (1988) Biochemical and Biophysical Research Communications , vol.157 , Issue.3 , pp. 1190-1196
    • Falcon, C.1    Pfliegler, G.2    Deckmyn, H.3    Vermylen, J.4
  • 168
    • 0024213166 scopus 로고
    • Insulin directly reduces platelet sensitivity to aggregating agents. Studies in vitro and in vivo
    • M. Trovati, G. Anfossi, F. Cavalot, P. Massucco, E. Mularoni, and G. Emanuelli, "Insulin directly reduces platelet sensitivity to aggregating agents. Studies in vitro and in vivo," Diabetes, Vol. 37, no. 6, pp. 780-786, 1988.
    • (1988) Diabetes , vol.37 , Issue.6 , pp. 780-786
    • Trovati, M.1    Anfossi, G.2    Cavalot, F.3    Massucco, P.4    Mularoni, E.5    Emanuelli, G.6
  • 169
    • 0021960112 scopus 로고
    • Platelet insulin receptor determination in non-insulin dependent diabetes mellitus
    • M. Udvardy, G. Pfliegler, and K. Rak, "Platelet insulin receptor determination in non-insulin dependent diabetes mellitus," Cellular and Molecular Life Sciences, Vol. 41, no. 3, pp. 422-423, 1985.
    • (1985) Cellular and Molecular Life Sciences , vol.41 , Issue.3 , pp. 422-423
    • Udvardy, M.1    Pfliegler, G.2    Rak, K.3
  • 170
    • 0026089213 scopus 로고
    • Restoration by insulin of impaired prostaglandin E1/I2 receptor activity of platelets in acute ischemic heart disease
    • N. N. Kahn, H. S. Mueller, and A. K. Sinha, "Restoration by insulin of impaired prostaglandin E1/I2 receptor activity of platelets in acute ischemic heart disease," Circulation Research, Vol. 68, no. 1, pp. 245-254, 1991.
    • (1991) Circulation Research , vol.68 , Issue.1 , pp. 245-254
    • Kahn, N.N.1    Mueller, H.S.2    Sinha, A.K.3
  • 171
    • 0035407264 scopus 로고    scopus 로고
    • Pathophysiology of oxidative stress in diabetes mellitus
    • B. Lipinski, "Pathophysiology of oxidative stress in diabetes mellitus," Journal of Diabetes and its Complications, Vol. 15, no. 4, pp. 203-210, 2001.
    • (2001) Journal of Diabetes and its Complications , vol.15 , Issue.4 , pp. 203-210
    • Lipinski, B.1
  • 172
    • 0025096104 scopus 로고
    • Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose
    • J. V. Hunt, C. C. Smith, and S. P. Wolff, "Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose," Diabetes, Vol. 39, no. 11, pp. 1420-1424, 1990.
    • (1990) Diabetes , vol.39 , Issue.11 , pp. 1420-1424
    • Hunt, J.V.1    Smith, C.C.2    Wolff, S.P.3
  • 173
    • 0022854527 scopus 로고
    • The regulation of the biosynthesis of prostaglandins and leukotrienes
    • W. E. Lands and R. J. Kulmacz, "The regulation of the biosynthesis of prostaglandins and leukotrienes," Progress in Lipid Research, Vol. 25, no. 1-4, pp. 105-109, 1986.
    • (1986) Progress in Lipid Research , vol.25 , Issue.1-4 , pp. 105-109
    • Lands, W.E.1    Kulmacz, R.J.2
  • 174
    • 0024195210 scopus 로고
    • Metabolism of fatty acids by platelets and the functions of various metabolites in mediating platelet function
    • M. Lagarde, "Metabolism of fatty acids by platelets and the functions of various metabolites in mediating platelet function," Progress in Lipid Research, Vol. 27, no. 2, pp. 135-152, 1988.
    • (1988) Progress in Lipid Research , vol.27 , Issue.2 , pp. 135-152
    • Lagarde, M.1
  • 175
    • 17544394772 scopus 로고    scopus 로고
    • Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status
    • E. Véricel, C. Januel, M. Carreras, P. Moulin, and M. Lagarde, "Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status," Diabetes, Vol. 53, no. 4, pp. 1046-1051, 2004.
    • (2004) Diabetes , vol.53 , Issue.4 , pp. 1046-1051
    • Véricel, E.1    Januel, C.2    Carreras, M.3    Moulin, P.4    Lagarde, M.5
  • 176
    • 0035652821 scopus 로고    scopus 로고
    • 12(S)-hydroperoxy-eicosatetraenoic acid increases arachidonic acid availability in collagen-primed platelets
    • C. Calzada, E. Véricel, B. Mitel, L. Coulon, and M. Lagarde, "12(S)-hydroperoxy-eicosatetraenoic acid increases arachidonic acid availability in collagen-primed platelets," Journal of Lipid Research, Vol. 42, no. 9, pp. 1467-1473, 2001.
    • (2001) Journal of Lipid Research , vol.42 , Issue.9 , pp. 1467-1473
    • Calzada, C.1    Véricel, E.2    Mitel, B.3    Coulon, L.4    Lagarde, M.5
  • 177
    • 0031453235 scopus 로고    scopus 로고
    • Platelet-leukocyte-cross-talk in diabetes mellitus
    • D. Tschoepe, U. Rauch, and B. Schwippert, "Platelet-leukocyte-cross-talk in diabetes mellitus," Hormone and Metabolic Research, Vol. 29, no. 12, pp. 631-635, 1997.
    • (1997) Hormone and Metabolic Research , vol.29 , Issue.12 , pp. 631-635
    • Tschoepe, D.1    Rauch, U.2    Schwippert, B.3
  • 178
    • 0019857575 scopus 로고
    • Fibrinogen binding and ADP-induced aggregation in platelets from diabetic subjects
    • H. Lee, R. C. Paton, P. Passa, and J. P. Caen, "Fibrinogen binding and ADP-induced aggregation in platelets from diabetic subjects," Thrombosis Research, Vol. 24, no. 1-2, pp. 143-150, 1981.
    • (1981) Thrombosis Research , vol.24 , Issue.1-2 , pp. 143-150
    • Lee, H.1    Paton, R.C.2    Passa, P.3    Caen, J.P.4
  • 180
    • 0022359246 scopus 로고
    • Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients
    • R. K. Mayfield, P. V. Halushka, H. J. Wohltmann, et al, "Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients," Diabetes, Vol. 34, no. 11, pp. 1127-1133, 1985.
    • (1985) Diabetes , vol.34 , Issue.11 , pp. 1127-1133
    • Mayfield, R.K.1    Halushka, P.V.2    Wohltmann, H.J.3
  • 181
    • 0037461106 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on soluble CD40L in patients with type 2 diabetes and coronary artery disease
    • N. Marx, A. Imhof, J. Froehlich, et al, "Effect of rosiglitazone treatment on soluble CD40L in patients with type 2 diabetes and coronary artery disease," Circulation, Vol. 107, no. 15, pp. 1954-1957, 2003.
    • (2003) Circulation , vol.107 , Issue.15 , pp. 1954-1957
    • Marx, N.1    Imhof, A.2    Froehlich, J.3
  • 183
    • 27844545767 scopus 로고    scopus 로고
    • Signalling role of adipose tissue: Adipokines and inflammation in obesity
    • P. Trayhurn and I. S. Wood, "Signalling role of adipose tissue: adipokines and inflammation in obesity," Biochemical Society Transactions, Vol. 33, part 5, pp. 1078-1081, 2005.
    • (2005) Biochemical Society Transactions , vol.33 , pp. 1078-1081
    • Trayhurn, P.1    Wood, I.S.2
  • 184
    • 20344400660 scopus 로고    scopus 로고
    • Adipocyte signaling and lipid homeostasis: Sequelae of insulin-resistant adipose tissue
    • Y.-H. Yu and H. N. Ginsberg, "Adipocyte signaling and lipid homeostasis: sequelae of insulin-resistant adipose tissue," Circulation Research, Vol. 96, no. 10, pp. 1042-1052, 2005.
    • (2005) Circulation Research , vol.96 , Issue.10 , pp. 1042-1052
    • Yu, Y.-H.1    Ginsberg, H.N.2
  • 185
    • 0035825152 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug prescribing: Past, present, and future
    • R. Jones, "Nonsteroidal anti-inflammatory drug prescribing: past, present, and future," The American Journal of Medicine, Vol. 110, no. 1, supplement 1, pp. S4-S7, 2001.
    • (2001) The American Journal of Medicine , vol.110 , Issue.1 , pp. S4-S7
    • Jones, R.1
  • 189
    • 33645063230 scopus 로고    scopus 로고
    • Sex differences in platelet reactivity and response to low-dose aspirin therapy
    • D. M. Becker, J. Segal, D. Vaidya, et al, "Sex differences in platelet reactivity and response to low-dose aspirin therapy," Journal of the American Medical Association, Vol. 295, no. 12, pp. 1420-1427, 2006.
    • (2006) Journal of the American Medical Association , vol.295 , Issue.12 , pp. 1420-1427
    • Becker, D.M.1    Segal, J.2    Vaidya, D.3
  • 190
    • 33645861080 scopus 로고    scopus 로고
    • Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events
    • D. L. Bhatt, K. A. A. Fox, W. Hacke, et al, "Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events," The New England Journal of Medicine, Vol. 354, no. 16, pp. 1706-1717, 2006.
    • (2006) The New England Journal of Medicine , vol.354 , Issue.16 , pp. 1706-1717
    • Bhatt, D.L.1    Fox, K.A.A.2    Hacke, W.3
  • 191
    • 4143064763 scopus 로고    scopus 로고
    • Clopidogrel added to aspirin versus aspirin alone in secondary prevention and high-risk primary prevention: Rationale and design of the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance (CHARISMA) trial
    • D. L. Bhatt and E. J. Topol, "Clopidogrel added to aspirin versus aspirin alone in secondary prevention and high-risk primary prevention: rationale and design of the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance (CHARISMA) trial," American Heart Journal, Vol. 148, no. 2, pp. 263-268, 2004.
    • (2004) American Heart Journal , vol.148 , Issue.2 , pp. 263-268
    • Bhatt, D.L.1    Topol, E.J.2
  • 192
    • 0034660472 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura associated with clopidogrel
    • C. L. Bennett, J. M. Connors, J. M. Carwile, et al, "Thrombotic thrombocytopenic purpura associated with clopidogrel," The New England Journal of Medicine, Vol. 342, no. 24, pp. 1773-1777, 2000.
    • (2000) The New England Journal of Medicine , vol.342 , Issue.24 , pp. 1773-1777
    • Bennett, C.L.1    Connors, J.M.2    Carwile, J.M.3
  • 193
    • 0033518847 scopus 로고    scopus 로고
    • Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting
    • S. R. Steinhubl, W. A. Tan, J. M. Foody, and E. J. Topol, "Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting," Journal of the American Medical Association, Vol. 281, no. 9, pp. 806-810, 1999.
    • (1999) Journal of the American Medical Association , vol.281 , Issue.9 , pp. 806-810
    • Steinhubl, S.R.1    Tan, W.A.2    Foody, J.M.3    Topol, E.J.4
  • 194
    • 0035227860 scopus 로고    scopus 로고
    • Oral glycoprotein IIb/IIIa antagonists in coronary artery disease
    • D. P. Chew and D. L. Bhatt, "Oral glycoprotein IIb/IIIa antagonists in coronary artery disease," Current Cardiology Reports, Vol. 3, no. 1, pp. 63-71, 2001.
    • (2001) Current Cardiology Reports , vol.3 , Issue.1 , pp. 63-71
    • Chew, D.P.1    Bhatt, D.L.2
  • 195
    • 0035895332 scopus 로고    scopus 로고
    • Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: A meta-analysis of phase III multicenter randomized trials
    • D. P. Chew, D. L. Bhatt, S. Sapp, and E. J. Topol, "Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials," Circulation, Vol. 103, no. 2, pp. 201-206, 2001.
    • (2001) Circulation , vol.103 , Issue.2 , pp. 201-206
    • Chew, D.P.1    Bhatt, D.L.2    Sapp, S.3    Topol, E.J.4
  • 196
    • 33744813015 scopus 로고    scopus 로고
    • The L162V polymorphism at the peroxisome proliferator activated receptor α locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: The veterans affairs HDL intervention trial (VA-HIT)
    • E. S. Tai, D. Collins, S. J. Robins, et al, "The L162V polymorphism at the peroxisome proliferator activated receptor α locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT)," Atherosclerosis, Vol. 187, no. 1, pp. 153-160, 2006.
    • (2006) Atherosclerosis , vol.187 , Issue.1 , pp. 153-160
    • Tai, E.S.1    Collins, D.2    Robins, S.J.3
  • 197
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
    • A. Keech, R. J. Simes, P. Barter, et al, "Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial," The Lancet, Vol. 366, no. 9500, pp. 1849-1861, 2005.
    • (2005) The Lancet , vol.366 , Issue.9500 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, P.3
  • 198
    • 23644456172 scopus 로고    scopus 로고
    • Therapeutic roles of peroxisome proliferator-activated receptor agonists
    • B. Staels and J.-C. Fruchart, "Therapeutic roles of peroxisome proliferator-activated receptor agonists," Diabetes, Vol. 54, no. 8, pp. 2460-2470, 2005.
    • (2005) Diabetes , vol.54 , Issue.8 , pp. 2460-2470
    • Staels, B.1    Fruchart, J.-C.2
  • 200
    • 0035115289 scopus 로고    scopus 로고
    • Troglitazone and liver function abnormalities: Lessons from a prescription event monitoring study and spontaneous reporting
    • P. Biswas, L. V. Wilton, and S. A. Shakir, "Troglitazone and liver function abnormalities: lessons from a prescription event monitoring study and spontaneous reporting," Drug Safety, Vol. 24, no. 2, pp. 149-154, 2001.
    • (2001) Drug Safety , vol.24 , Issue.2 , pp. 149-154
    • Biswas, P.1    Wilton, L.V.2    Shakir, S.A.3
  • 201
    • 85077298357 scopus 로고    scopus 로고
    • Troglitazone withdrawn from market
    • "Troglitazone withdrawn from market," American Journal of Health-System Pharmacy, Vol. 57, no. 9, p. 834, 2000.
    • (2000) American Journal of Health-System Pharmacy , vol.57 , Issue.9 , pp. 834
  • 202
    • 32044446983 scopus 로고    scopus 로고
    • Implications of rosiglitazone and pioglitazone on cardiovascular risk in patients with type 2 diabetes mellitus
    • B. K. Irons, R. S. Greene, T. A. Mazzolini, K. L. Edwards, and R. B. Sleeper, "Implications of rosiglitazone and pioglitazone on cardiovascular risk in patients with type 2 diabetes mellitus," Pharmacotherapy, Vol. 26, no. 2, pp. 168-181, 2006.
    • (2006) Pharmacotherapy , vol.26 , Issue.2 , pp. 168-181
    • Irons, B.K.1    Greene, R.S.2    Mazzolini, T.A.3    Edwards, K.L.4    Sleeper, R.B.5
  • 203
    • 26244453309 scopus 로고    scopus 로고
    • Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive study (PROspective pioglitAzone clinical trial in macroVascular events): A randomised controlled trial
    • J. A. Dormandy, B. Charbonnel, D. J. Eckland, et al, "Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial in macroVascular Events): a randomised controlled trial," The Lancet, Vol. 366, no. 9493, pp. 1279-1289, 2005.
    • (2005) The Lancet , vol.366 , Issue.9493 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.J.3
  • 204
    • 0037031267 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
    • S. M. Haffner, A. S. Greenberg, W. M. Weston, H. Chen, K. Williams, and M. I. Freed, "Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus," Circulation, Vol. 106, no. 6, pp. 679-684, 2002.
    • (2002) Circulation , vol.106 , Issue.6 , pp. 679-684
    • Haffner, S.M.1    Greenberg, A.S.2    Weston, W.M.3    Chen, H.4    Williams, K.5    Freed, M.I.6
  • 205
    • 33845405222 scopus 로고    scopus 로고
    • Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
    • S. E. Kahn, S. M. Haffner, M. A. Heise, et al, "Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy," The New England Journal of Medicine, Vol. 355, no. 23, pp. 2427-2443, 2006.
    • (2006) The New England Journal of Medicine , vol.355 , Issue.23 , pp. 2427-2443
    • Kahn, S.E.1    Haffner, S.M.2    Heise, M.A.3
  • 206
    • 33847699014 scopus 로고    scopus 로고
    • DREAM study: Prevention of type 2 diabetes with ramipril and/or rosiglitazone in persons with dysglycaemia but no cardiovascular desease
    • A. J. Scheen, "DREAM study: prevention of type 2 diabetes with ramipril and/or rosiglitazone in persons with dysglycaemia but no cardiovascular desease," Revue Medicale de Liege, Vol. 61, no. 10, pp. 728-732, 2006.
    • (2006) Revue Medicale de Liege , vol.61 , Issue.10 , pp. 728-732
    • Scheen, A.J.1
  • 207
    • 34250865768 scopus 로고    scopus 로고
    • Rosiglitazone evaluated for cardiovascular outcomes - An interim analysis
    • P. D. Home, S. J. Pocock, H. Beck-Nielsen, et al, "Rosiglitazone evaluated for cardiovascular outcomes - an interim analysis," The New England Journal of Medicine, Vol. 357, no. 1, pp. 28-38, 2007.
    • (2007) The New England Journal of Medicine , vol.357 , Issue.1 , pp. 28-38
    • Home, P.D.1    Pocock, S.J.2    Beck-Nielsen, H.3
  • 208
    • 1642446053 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ: Too much of a good thing causes harm
    • T.-A. Cock, S. M. Houten, and J. Auwerx, "Peroxisome proliferator-activated receptor-γ: too much of a good thing causes harm," EMBO Reports, Vol. 5, no. 2, pp. 142-147, 2004.
    • (2004) EMBO Reports , vol.5 , Issue.2 , pp. 142-147
    • Cock, T.-A.1    Houten, S.M.2    Auwerx, J.3
  • 209
    • 0037177058 scopus 로고    scopus 로고
    • The dawn of the SPPARMs?
    • S. M. Rangwala and M. A. Lazar, "The dawn of the SPPARMs?" Science's STKE, Vol. 2002, no. 121, p. pe9, 2002.
    • (2002) Science's STKE , vol.2002 , Issue.121 , pp. pe9
    • Rangwala, S.M.1    Lazar, M.A.2
  • 210
    • 33947576591 scopus 로고    scopus 로고
    • Discovery of tertiary aminoacids as dual PPARα/γ agonists-I
    • P. V. Devasthale, S. Chen, Y. Jeon, et al, "Discovery of tertiary aminoacids as dual PPARα/γ agonists-I," Bioorganic & Medicinal Chemistry Letters, Vol. 17, no. 8, pp. 2312-2316, 2007.
    • (2007) Bioorganic & Medicinal Chemistry Letters , vol.17 , Issue.8 , pp. 2312-2316
    • Devasthale, P.V.1    Chen, S.2    Jeon, Y.3
  • 211
    • 20144370408 scopus 로고    scopus 로고
    • Design and synthesis of N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [muraglitazar/BMS-298585], a novel peroxisome proliferator-activated receptor α/γ dual agonist with efficacious glucose and lipid-lowering activities
    • P. V. Devasthale, S. Chen, Y Jeon, et al, "Design and synthesis of N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [muraglitazar/BMS-298585], a novel peroxisome proliferator-activated receptor α/γ dual agonist with efficacious glucose and lipid-lowering activities," Journal of Medicinal Chemistry, Vol. 48, no. 6, pp. 2248-2250, 2005.
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.6 , pp. 2248-2250
    • Devasthale, P.V.1    Chen, S.2    Jeon, Y.3
  • 213
    • 0030069325 scopus 로고    scopus 로고
    • Activation of gene transcription by prostacyclin analogues is mediated by the peroxisome-proliferators-activated receptor (PPAR)
    • R. Hertz, I. Berman, D. Keppler, and J. Bar-Tana, "Activation of gene transcription by prostacyclin analogues is mediated by the peroxisome-proliferators-activated receptor (PPAR)," European Journal of Biochemistry, Vol. 235, no. 1-2, pp. 242-247, 1996.
    • (1996) European Journal of Biochemistry , vol.235 , Issue.1-2 , pp. 242-247
    • Hertz, R.1    Berman, I.2    Keppler, D.3    Bar-Tana, J.4
  • 214
    • 0034094324 scopus 로고    scopus 로고
    • PPARδ functions as a prostacyclin receptor in blastocyst implantation
    • H. Lim and S. K. Dey, "PPARδ functions as a prostacyclin receptor in blastocyst implantation," Trends in Endocrinology and Metabolism, Vol. 11, no. 4, pp. 137-142, 2000.
    • (2000) Trends in Endocrinology and Metabolism , vol.11 , Issue.4 , pp. 137-142
    • Lim, H.1    Dey, S.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.