메뉴 건너뛰기




Volumn 14, Issue 1, 2002, Pages 51-58

Aspirin resistance and genetic polymorphisms

Author keywords

Aspirin; Cyclooxygenase; Ischemic events; Myocardial infarction; Platelets; Polymorphisms

Indexed keywords

ACETYLSALICYLIC ACID; ALLOANTIGEN; ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GLYCOPROTEIN IIIA; HEPARIN; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; SERINE; THROMBOCYTE SPECIFIC ALLOANTIGEN 1; THROMBOCYTE SPECIFIC ALLOANTIGEN 2; TICLOPIDINE; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2; WARFARIN;

EID: 0037288750     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022066305399     Document Type: Review
Times cited : (135)

References (51)
  • 1
    • 0035865322 scopus 로고    scopus 로고
    • A map of the human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • International SNP Map Working Group. A map of the human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 2001;409:928-933.
    • (2001) Nature , vol.409 , pp. 928-933
  • 2
    • 0022485106 scopus 로고
    • Haemostatic function and ischaemic heart disease: Principal results of the Northwick Park Heart Study
    • Meade TW, Mellows S, Brozovic M, et al. Haemostatic function and ischaemic heart disease: Principal results of the Northwick Park Heart Study. Lancet 1986;2:533-537.
    • (1986) Lancet , vol.2 , pp. 533-537
    • Meade, T.W.1    Mellows, S.2    Brozovic, M.3
  • 4
    • 0025948224 scopus 로고
    • von Willebrand factor in plasma: A novel risk factor for recurrent myocardial infarction and death
    • Jansson JK, Nilsson TK, Johnson O. von Willebrand factor in plasma: A novel risk factor for recurrent myocardial infarction and death. Br Heart J 1991;66:351-355.
    • (1991) Br Heart J , vol.66 , pp. 351-355
    • Jansson, J.K.1    Nilsson, T.K.2    Johnson, O.3
  • 5
    • 0023185776 scopus 로고
    • Plasminogen activatory inhibitor in plasma: Risk factor for recurrent myocardial infarction
    • Hamsten A, De Faire U, Walldius G, et al. Plasminogen activatory inhibitor in plasma: Risk factor for recurrent myocardial infarction. Lancet 1987;2:3-9.
    • (1987) Lancet , vol.2 , pp. 3-9
    • Hamsten, A.1    De Faire, U.2    Walldius, G.3
  • 6
    • 0028226514 scopus 로고
    • Prospective study of endogenous tissue plasminogen activator and risk of stroke
    • Ridker PM, Hennekens CH, Stampfer MJ, Manson JE, Vaughan DE. Prospective study of endogenous tissue plasminogen activator and risk of stroke. Lancet 1994;343:940-943.
    • (1994) Lancet , vol.343 , pp. 940-943
    • Ridker, P.M.1    Hennekens, C.H.2    Stampfer, M.J.3    Manson, J.E.4    Vaughan, D.E.5
  • 8
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. NEJM 2001;345:494-502.
    • (2001) NEJM , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3
  • 9
    • 0035908781 scopus 로고    scopus 로고
    • Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study
    • Mehta SR, Yusuf S, Peters RJ, et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study. Lancet 2001;358:527-533.
    • (2001) Lancet , vol.358 , pp. 527-533
    • Mehta, S.R.1    Yusuf, S.2    Peters, R.J.3
  • 10
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu TKH, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991;64:1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.H.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 11
    • 0032514474 scopus 로고    scopus 로고
    • A dual thrombin receptor system for platelet activation
    • Kahn ML, Zheng YW, Huang W, et al. A dual thrombin receptor system for platelet activation. Nature 1998;394:690-694.
    • (1998) Nature , vol.394 , pp. 690-694
    • Kahn, M.L.1    Zheng, Y.W.2    Huang, W.3
  • 12
    • 0028289804 scopus 로고
    • New insights into the mechanisms of platelet adhesion and aggregation
    • Ruggeri ZM. New insights into the mechanisms of platelet adhesion and aggregation. Semin Hematol 1994;31:229-239.
    • (1994) Semin Hematol , vol.31 , pp. 229-239
    • Ruggeri, Z.M.1
  • 13
    • 0033573790 scopus 로고    scopus 로고
    • Platelet GPIIb/IIIa blockers
    • Topol EJ, Byzova TV, Plow E. Platelet GPIIb/IIIa blockers. Lancet 1999;353:227-231.
    • (1999) Lancet , vol.353 , pp. 227-231
    • Topol, E.J.1    Byzova, T.V.2    Plow, E.3
  • 14
    • 0008926519 scopus 로고    scopus 로고
    • Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes
    • The PURSUIT Trial Investigators: Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes. N Engl J Med 1998;339:436-443.
    • (1998) N Engl J Med , vol.339 , pp. 436-443
  • 15
    • 2642599026 scopus 로고    scopus 로고
    • Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction
    • The Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study Investigators. Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction. N Engl J Med 1998;338:1488-1497.
    • (1998) N Engl J Med , vol.338 , pp. 1488-1497
  • 16
    • 0030918995 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE study
    • The CAPTURE Investigators: Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE study. Lancet 1997;349:1429-1435.
    • (1997) Lancet , vol.349 , pp. 1429-1435
  • 17
    • 0026767437 scopus 로고
    • The molecular biology of human platelet proteins
    • Kunicki TJ, Newman PJ. The molecular biology of human platelet proteins. Blood 1992;80:1396-1404.
    • (1992) Blood , vol.80 , pp. 1396-1404
    • Kunicki, T.J.1    Newman, P.J.2
  • 19
    • 0035833502 scopus 로고    scopus 로고
    • The coxibs, selective inhibitors of cyclooxygenase-2
    • Fitzgerald GA, Patrono C. The coxibs, selective inhibitors of cyclooxygenase-2. NEJM 2001;354:433-442.
    • (2001) NEJM , vol.354 , pp. 433-442
    • Fitzgerald, G.A.1    Patrono, C.2
  • 20
    • 0023968630 scopus 로고
    • Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
    • DeWitt DL, Smith WL. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci USA 1988;85:1412-1416.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1412-1416
    • Dewitt, D.L.1    Smith, W.L.2
  • 21
    • 0025248570 scopus 로고
    • The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases
    • DeWitt DL, El-Harith EA, Kraemer SA, et al. The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases. J Biol Chem 1990;265:5192-5198.
    • (1990) J Biol Chem , vol.265 , pp. 5192-5198
    • Dewitt, D.L.1    El-Harith, E.A.2    Kraemer, S.A.3
  • 23
    • 0035924765 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors and the antiplatelet effects of aspirin
    • Catella-Lawson F, et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. NEJM 2001;345:1809.
    • (2001) NEJM , vol.345 , pp. 1809
    • Catella-Lawson, F.1
  • 25
    • 0034671987 scopus 로고    scopus 로고
    • Distinct influences of carboxyl terminal segment structure on function in the two isoforms of prostaglandin H synthase
    • Guo Q, Kulmacz RJ. Distinct influences of carboxyl terminal segment structure on function in the two isoforms of prostaglandin H synthase. Arch Biochem Biophys 2000;384:269-279.
    • (2000) Arch Biochem Biophys , vol.384 , pp. 269-279
    • Guo, Q.1    Kulmacz, R.J.2
  • 26
    • 0028961611 scopus 로고
    • Prostaglandin H synthase-1: Evaluation of c-terminus function
    • Ren Y, Loosemitchell DS, Kulmacz RJ. Prostaglandin H synthase-1: Evaluation of c-terminus function. Arch Biochem Biophys 1995;316:751-757.
    • (1995) Arch Biochem Biophys , vol.316 , pp. 751-757
    • Ren, Y.1    Loosemitchell, D.S.2    Kulmacz, R.J.3
  • 27
    • 0029664422 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and -2 of endothelial cells utilize exogenous or endogenous arachidonic acid for transcellular production of thromboxane
    • Karim S, Habib A, Levy-Toledano S, et al. Cyclooxygenase-1 and -2 of endothelial cells utilize exogenous or endogenous arachidonic acid for transcellular production of thromboxane. J Biol Chem 1996;271:12042-12048.
    • (1996) J Biol Chem , vol.271 , pp. 12042-12048
    • Karim, S.1    Habib, A.2    Levy-Toledano, S.3
  • 29
    • 17344367171 scopus 로고    scopus 로고
    • Up-regulation of prostacyclin synthesis-related gene expression by shear stress in vascular endothelial cells
    • Okahara K, Sun B, Kambayashi J. Up-regulation of prostacyclin synthesis-related gene expression by shear stress in vascular endothelial cells. Arterioscler Thromb Vasc Biol 1998;18:1922.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1922
    • Okahara, K.1    Sun, B.2    Kambayashi, J.3
  • 30
    • 0027447701 scopus 로고
    • Aspirin response and failure in cerebral infarction
    • Helgason CM, Tortorice KL, Winkler SR, et al. Aspirin response and failure in cerebral infarction. Stroke 1993;24:345-350.
    • (1993) Stroke , vol.24 , pp. 345-350
    • Helgason, C.M.1    Tortorice, K.L.2    Winkler, S.R.3
  • 31
    • 0345040152 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in human platelets as a possible factor in aspirin resistance
    • Weber AA, Zimmermann KM, Meyer-Kirchrath J, Schror K. Cyclooxygenase-2 in human platelets as a possible factor in aspirin resistance. Lancet 1999;353:900.
    • (1999) Lancet , vol.353 , pp. 900
    • Weber, A.A.1    Zimmermann, K.M.2    Meyer-Kirchrath, J.3    Schror, K.4
  • 32
    • 0035451677 scopus 로고    scopus 로고
    • Roles of cyclooxygenase (COX)-1 and COX-2 in prostanoid production by human endothelial cells: Selective up-regulation of prostacyclin synthesis by COX-2
    • Caughey GF, Cleland LG, Penglis PS, Gamble JR, James MJ. Roles of cyclooxygenase (COX)-1 and COX-2 in prostanoid production by human endothelial cells: Selective up-regulation of prostacyclin synthesis by COX-2. J Immunol 2001;167:2831-2838.
    • (2001) J Immunol , vol.167 , pp. 2831-2838
    • Caughey, G.F.1    Cleland, L.G.2    Penglis, P.S.3    Gamble, J.R.4    James, M.J.5
  • 33
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • Eikelboom JW, Hirsh J, Weit JI, et al. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002:105:1650-1655.
    • (2002) Circulation , vol.105 , pp. 1650-1655
    • Eikelboom, J.W.1    Hirsh, J.2    Weit, J.I.3
  • 34
    • 0031039680 scopus 로고    scopus 로고
    • Platelet alloantigens: Cardiovascular as well as immunological risk factors?
    • Newman PJ. Platelet alloantigens: Cardiovascular as well as immunological risk factors? Lancet 1997;349:370-371.
    • (1997) Lancet , vol.349 , pp. 370-371
    • Newman, P.J.1
  • 35
    • 0031586472 scopus 로고    scopus 로고
    • Platelet glycoprotein IIIa polymorphism and coronary thrombosis
    • Nurden AT. Platelet glycoprotein IIIa polymorphism and coronary thrombosis. Lancet 1997;350:1189-1191.
    • (1997) Lancet , vol.350 , pp. 1189-1191
    • Nurden, A.T.1
  • 36
    • 18244414272 scopus 로고    scopus 로고
    • Platelet GP IIIa PLA polymorphisms display different sensitivities to agonists
    • Michaelson AD, Furman MI, Goldschmidt-Clermont P, et al. Platelet GP IIIa PLA polymorphisms display different sensitivities to agonists. Circulation 2000;101:1013-1018.
    • (2000) Circulation , vol.101 , pp. 1013-1018
    • Michaelson, A.D.1    Furman, M.I.2    Goldschmidt-Clermont, P.3
  • 37
    • 0033760129 scopus 로고    scopus 로고
    • Deffective platelet response to arachidonic acid and thromboxane A(2) in subjects with PL(A2) polymorphism of beta(3) subunit glycoprotein IIIa
    • Andrioli G, Minuz P, Solero P, et al. Deffective platelet response to arachidonic acid and thromboxane A(2) in subjects with PL(A2) polymorphism of beta(3) subunit glycoprotein IIIa. British Journal of Haematology 2000;110:911-918.
    • (2000) British Journal of Haematology , vol.110 , pp. 911-918
    • Andrioli, G.1    Minuz, P.2    Solero, P.3
  • 38
    • 0033761053 scopus 로고    scopus 로고
    • Relationship between bleeding time, aspirin and the PLA1/A2 polymorphism of platelet glycoprotein IIIa
    • Szczeklik A, Undas A, Sanak M, Frolow M, Wegrzyn W. Relationship between bleeding time, aspirin and the PLA1/A2 polymorphism of platelet glycoprotein IIIa. British Journal of Haematology 2000;110:965-967.
    • (2000) British Journal of Haematology , vol.110 , pp. 965-967
    • Szczeklik, A.1    Undas, A.2    Sanak, M.3    Frolow, M.4    Wegrzyn, W.5
  • 39
    • 0029875770 scopus 로고    scopus 로고
    • A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis
    • Weiss EJ, Bray PF, Tayback M, et al. A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med 1996;334:1090-1094.
    • (1996) N Engl J Med , vol.334 , pp. 1090-1094
    • Weiss, E.J.1    Bray, P.F.2    Tayback, M.3
  • 40
    • 0031586491 scopus 로고    scopus 로고
    • Platelet glycoprotein IIIa polymorphisms and the risk of coronary stent thrombosis
    • Walter DH, Schachinger V, Eisner M, Dimmeler S, Zeiher AM. Platelet glycoprotein IIIa polymorphisms and the risk of coronary stent thrombosis. Lancet 1997;350:1217-1219.
    • (1997) Lancet , vol.350 , pp. 1217-1219
    • Walter, D.H.1    Schachinger, V.2    Eisner, M.3    Dimmeler, S.4    Zeiher, A.M.5
  • 41
    • 0033514507 scopus 로고    scopus 로고
    • PLA polymorphism of platelet glycoprotein IIIa and risk of restenosis after coronary stent placement
    • Kastrati A, Schomig A, Seyfarth M, et al. PLA polymorphism of platelet glycoprotein IIIa and risk of restenosis after coronary stent placement. Circulation 1999;99:1005-1010.
    • (1999) Circulation , vol.99 , pp. 1005-1010
    • Kastrati, A.1    Schomig, A.2    Seyfarth, M.3
  • 42
    • 0030882209 scopus 로고    scopus 로고
    • Association of the platelet PLA polymorphism of glycoprotein IIb/IIIa and the fibrinogen Bβ 448 polymorphism with myocardial infarction and extent coronary artery disease
    • Carter AM, Ossei-Gerning N, Wilson IJ, Grant PJ. Association of the platelet PLA polymorphism of glycoprotein IIb/IIIa and the fibrinogen Bβ 448 polymorphism with myocardial infarction and extent coronary artery disease. Circulation 1997;96:1424-1431.
    • (1997) Circulation , vol.96 , pp. 1424-1431
    • Carter, A.M.1    Ossei-Gerning, N.2    Wilson, I.J.3    Grant, P.J.4
  • 43
    • 0033169099 scopus 로고    scopus 로고
    • Prothrombotic genetic risk factors in young survivors of myocardial infarction
    • Ardissino PM, Mannucci PM, Merlini PA, et al. Prothrombotic genetic risk factors in young survivors of myocardial infarction. Blood 1999;94:46-51.
    • (1999) Blood , vol.94 , pp. 46-51
    • Ardissino, P.M.1    Mannucci, P.M.2    Merlini, P.A.3
  • 44
    • 0033586430 scopus 로고    scopus 로고
    • Platelet glycoprotein IIIa polymorphism, aspirin, and thrombin generation
    • (letter).
    • Undas A, Sanak M, Musial J, Szczeklik A. Platelet glycoprotein IIIa polymorphism, aspirin, and thrombin generation (letter). Lancet 1999;353:982-983.
    • (1999) Lancet , vol.353 , pp. 982-983
    • Undas, A.1    Sanak, M.2    Musial, J.3    Szczeklik, A.4
  • 46
    • 0030614495 scopus 로고    scopus 로고
    • PL(A1/A2) polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis
    • Ridker PM, et al. PL(A1/A2) polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis. Lancet 1997;349:385-388.
    • (1997) Lancet , vol.349 , pp. 385-388
    • Ridker, P.M.1
  • 47
    • 0031155630 scopus 로고    scopus 로고
    • The Leu 33/Pro polymorphism (PLA1/PLA2) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM study
    • Herrmann SM, Poirier O, Marques-Vidal P, et al. The Leu 33/Pro polymorphism (PLA1/PLA2) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM study. Thromb Haemost 1997;77:1179-1181.
    • (1997) Thromb Haemost , vol.77 , pp. 1179-1181
    • Herrmann, S.M.1    Poirier, O.2    Marques-Vidal, P.3
  • 48
    • 0027431790 scopus 로고
    • Variability of integrin a2 b1 activity on human platelets
    • Kunicki TJ, Orchekowski R, Annis D, Honda Y. Variability of integrin a2 b1 activity on human platelets. Blood 1993;82:2693.
    • (1993) Blood , vol.82 , pp. 2693
    • Kunicki, T.J.1    Orchekowski, R.2    Annis, D.3    Honda, Y.4
  • 49
    • 0030942489 scopus 로고    scopus 로고
    • Hereditary variation in platelet integrin alpha 2 beta 1 density is associated with two silent polymorphisms in the alpha 2 gene coding sequence
    • Kunicki TJ, Kritzik M, Annis DS, Nugent DJ. Hereditary variation in platelet integrin alpha 2 beta 1 density is associated with two silent polymorphisms in the alpha 2 gene coding sequence. Blood 1997;89:1939-1943.
    • (1997) Blood , vol.89 , pp. 1939-1943
    • Kunicki, T.J.1    Kritzik, M.2    Annis, D.S.3    Nugent, D.J.4
  • 50
    • 0001218842 scopus 로고    scopus 로고
    • Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction
    • Moshfegh K, Wuillemin WA, Redondo M, et al. Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction. Lancet 1999;353:351-354.
    • (1999) Lancet , vol.353 , pp. 351-354
    • Moshfegh, K.1    Wuillemin, W.A.2    Redondo, M.3
  • 51
    • 0030961921 scopus 로고    scopus 로고
    • Coronary risk factors and plaque morphology in men with coronary disease who died suddenly
    • Burke AP, Farb A, Malcom GT, Liang YH, Smialek J, Virmani R. Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. NEJM 1997;336:1276-1282.
    • (1997) NEJM , vol.336 , pp. 1276-1282
    • Burke, A.P.1    Farb, A.2    Malcom, G.T.3    Liang, Y.H.4    Smialek, J.5    Virmani, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.