-
1
-
-
0036146384
-
A novel heterozygous mutation in PPARγ gene in a patient with familial partial lipodystrophy
-
Agarwal AK, Garg A (2002) A novel heterozygous mutation in PPARγ gene in a patient with familial partial lipodystrophy. J Clin Endocrinol Metab 87: 408-411
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 408-411
-
-
Agarwal, A.K.1
Garg, A.2
-
2
-
-
0141448772
-
Adipokines, inflammation, and the endothelium in diabetes
-
Aldhahi W, Hamdy O (2003) Adipokines, inflammation, and the endothelium in diabetes. Curr Diab Rep 3: 293-298
-
(2003)
Curr. Diab. Rep.
, vol.3
, pp. 293-298
-
-
Aldhahi, W.1
Hamdy, O.2
-
3
-
-
0033624575
-
The common PPARγ Pro12AIa polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D et al (2000) The common PPARγ Pro12AIa polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80
-
(2000)
Nat. Genet.
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
-
4
-
-
0032588487
-
PPARγ, the ultimate thrifty gene
-
Auwerx J (1999) PPARγ, the ultimate thrifty gene. Diabetologia 42: 1033-1049
-
(1999)
Diabetologia
, vol.42
, pp. 1033-1049
-
-
Auwerx, J.1
-
5
-
-
0033213637
-
PPARγ is required for placental, cardiac, and adipose tissue development
-
Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, Koder A, Evans RM (1999) PPARγ is required for placental, cardiac, and adipose tissue development. Mol Cell 4: 585-595
-
(1999)
Mol. Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
Koder, A.7
Evans, R.M.8
-
6
-
-
0033599038
-
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
-
Barroso I et al (1999) Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402: 880-883
-
(1999)
Nature
, vol.402
, pp. 880-883
-
-
Barroso, I.1
-
7
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
Bluher M, Kahn BB, Kahn CR (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299: 572-574
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Bluher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
8
-
-
0348143232
-
Effect of meal sequence on postprandial lipid, glucose and insulin responses in young men
-
Burdge GC, Jones AE, Frye SM, Goodson L, Wootton SA (2003) Effect of meal sequence on postprandial lipid, glucose and insulin responses in young men. Eur J Clin Nutr 57: 1536-1544
-
(2003)
Eur. J. Clin. Nutr.
, vol.57
, pp. 1536-1544
-
-
Burdge, G.C.1
Jones, A.E.2
Frye, S.M.3
Goodson, L.4
Wootton, S.A.5
-
9
-
-
0035132330
-
PPARγ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
-
Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM (2001) PPARγ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 7: 48-52
-
(2001)
Nat. Med.
, vol.7
, pp. 48-52
-
-
Chawla, A.1
Barak, Y.2
Nagy, L.3
Liao, D.4
Tontonoz, P.5
Evans, R.M.6
-
10
-
-
0035097590
-
Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: Pleiotropic effects on CD36 expression and HDL
-
Chen Z et al (2001) Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: Pleiotropic effects on CD36 expression and HDL. Arterioscler Thromb Vasc Biol 21: 372-377
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, pp. 372-377
-
-
Chen, Z.1
-
11
-
-
0035957006
-
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor
-
Claudel T et al (2001) Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. Proc Natl Acad Sci USA 98: 2610-2615
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2610-2615
-
-
Claudel, T.1
-
12
-
-
0035093258
-
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice
-
Collins AR, Meehan WP, Kintscher U, Jackson S, Wakino S, Noh G, Palinski W, Hsueh WA, Law RE (2001) Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol 21: 365-371
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, pp. 365-371
-
-
Collins, A.R.1
Meehan, W.P.2
Kintscher, U.3
Jackson, S.4
Wakino, S.5
Noh, G.6
Palinski, W.7
Hsueh, W.A.8
Law, R.E.9
-
13
-
-
4243645912
-
Induction of adipocyte complement-related protein of 30 kilodaltons by PPARγ agonists: A potential mechanism of insulin sensitization
-
Combs TP et al (2002) Induction of adipocyte complement-related protein of 30 kilodaltons by PPARγ agonists: A potential mechanism of insulin sensitization. Endocrinology 143: 998-1007
-
(2002)
Endocrinology
, vol.143
, pp. 998-1007
-
-
Combs, T.P.1
-
14
-
-
0037674923
-
Inhibitory activity of clinical thiazolidinedione peroxisome proliferator activating receptor-γ ligands toward internal mammary artery, radial artery, and saphenous vein smooth muscle cell proliferation
-
de Dios ST, Bruemmer D, Dilley RJ, Ivey ME, Jennings GL, Law RE, Little PJ (2003) Inhibitory activity of clinical thiazolidinedione peroxisome proliferator activating receptor-γ ligands toward internal mammary artery, radial artery, and saphenous vein smooth muscle cell proliferation. Circulation 107: 2548-2550
-
(2003)
Circulation
, vol.107
, pp. 2548-2550
-
-
de Dios, S.T.1
Bruemmer, D.2
Dilley, R.J.3
Ivey, M.E.4
Jennings, G.L.5
Law, R.E.6
Little, P.J.7
-
15
-
-
0031595923
-
A Pro12AIa substitution in the human PPARγ2 is associated with decreased receptor activity, improved insulin sensitivity, and lowered body mass index
-
Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykkanen L, Kuusisto J, Laakso M, Fujimoto W, Auwerx J (1998) A Pro12AIa substitution in the human PPARγ2 is associated with decreased receptor activity, improved insulin sensitivity, and lowered body mass index. Nat Genet 20: 284-287
-
(1998)
Nat. Genet.
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamaki, J.4
Mykkanen, L.5
Kuusisto, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.9
-
16
-
-
0037423247
-
A war on obesity, not the obese
-
Friedman JM (2003) A war on obesity, not the obese. Science 299: 856-858
-
(2003)
Science
, vol.299
, pp. 856-858
-
-
Friedman, J.M.1
-
17
-
-
0034085884
-
A new thiazolidinedione, NC-2100, which is a weak PPAR-γ activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAγ obese mice
-
Fukui Y, Masui S, Osada S, Umesono K, Motojima K (2000) A new thiazolidinedione, NC-2100, which is a weak PPAR-γ activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAγ obese mice. Diabetes 49: 759-767
-
(2000)
Diabetes
, vol.49
, pp. 759-767
-
-
Fukui, Y.1
Masui, S.2
Osada, S.3
Umesono, K.4
Motojima, K.5
-
18
-
-
0141446024
-
Liver PPARγ contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
-
Gavrilova O, Haluzik M, Matsusue K, Cutson JJ, Johnson L, Dietz KR, Nicol CJ, Vinson C, Gonzalez FJ, Reitman ML (2003) Liver PPARγ contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J Biol Chem 278: 34268-34276
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsusue, K.3
Cutson, J.J.4
Johnson, L.5
Dietz, K.R.6
Nicol, C.J.7
Vinson, C.8
Gonzalez, F.J.9
Reitman, M.L.10
-
19
-
-
0034193776
-
Sir2 links chromatin silencing, metabolism, and aging
-
Guarente L (2000) Sir2 links chromatin silencing, metabolism, and aging. Genes Dev 14: 1021-1026
-
(2000)
Genes Dev.
, vol.14
, pp. 1021-1026
-
-
Guarente, L.1
-
20
-
-
0001001689
-
Effects of food restriction on aging: Separation of food intake and adiposity
-
Harrison DE, Archer JR, Astle CM (1984) Effects of food restriction on aging: Separation of food intake and adiposity. Proc Natl Acad Sci USA 81: 1835-1838
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 1835-1838
-
-
Harrison, D.E.1
Archer, J.R.2
Astle, C.M.3
-
21
-
-
12144286372
-
Adipose-specific PPARγ knockout causes insulin resistance in fat and liver but not in muscle
-
He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM, Evans RM (2003) Adipose-specific PPARγ knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci USA 9: 1491-1497
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.9
, pp. 1491-1497
-
-
He, W.1
Barak, Y.2
Hevener, A.3
Olson, P.4
Liao, D.5
Le, J.6
Nelson, M.7
Ong, E.8
Olefsky, J.M.9
Evans, R.M.10
-
22
-
-
0036894397
-
PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy
-
Hegele RA, Cao H, Frankowski C, Mathews ST, Leff T (2002) PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy. Diabetes 51: 3586-3590
-
(2002)
Diabetes
, vol.51
, pp. 3586-3590
-
-
Hegele, R.A.1
Cao, H.2
Frankowski, C.3
Mathews, S.T.4
Leff, T.5
-
23
-
-
0346027235
-
Muscle-specific PPARγ deletion causes insulin resistance
-
Hevener AL, He W, Barak Y, Le J, Bandyopadhyay G, Olson P, Wilkes J, Evans RM, Olefsky J (2003) Muscle-specific PPARγ deletion causes insulin resistance. Nat Med 9: 1491-1497
-
(2003)
Nat. Med.
, vol.9
, pp. 1491-1497
-
-
Hevener, A.L.1
He, W.2
Barak, Y.3
Le, J.4
Bandyopadhyay, G.5
Olson, P.6
Wilkes, J.7
Evans, R.M.8
Olefsky, J.9
-
24
-
-
0038776380
-
Inhibition of adipogenesis through MAP-kinase mediated phosphorylation of PPARγ
-
Hu E, Kim JB, Sarraf P, Spiegelman BM (1996) Inhibition of adipogenesis through MAP-kinase mediated phosphorylation of PPARγ. Science 274: 2100-2103
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Spiegelman, B.M.4
-
25
-
-
0031888958
-
PPARγ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang C, Ting AT, Seed B (1998) PPARγ agonists inhibit production of monocyte inflammatory cytokines. Nature 391: 82-86
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
26
-
-
0034920087
-
Inhibitory effect of pioglitazone on carotid arterial wall thickness in type 2 diabetes
-
Koshiyama H, Shimono D, Kuwamura N, Minamikawa J, Nakamura Y (2001) Inhibitory effect of pioglitazone on carotid arterial wall thickness in type 2 diabetes. J Clin Endocrinol Metab 86: 3452-3456
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 3452-3456
-
-
Koshiyama, H.1
Shimono, D.2
Kuwamura, N.3
Minamikawa, J.4
Nakamura, Y.5
-
27
-
-
0037312020
-
How does calorie restriction work?
-
Koubova J & Guarente L (2003) How does calorie restriction work? Genes Dev 17: 313-321
-
(2003)
Genes Dev.
, vol.17
, pp. 313-321
-
-
Koubova, J.1
Guarente, L.2
-
28
-
-
0344630205
-
Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice
-
Koutnikova H, Cock TA, Watanabe M, Houten SM, Champy MF, Dierich A, Auwerx J (2003) Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice. Proc Natl Acad Sci USA 100: 14457-14462
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14457-14462
-
-
Koutnikova, H.1
Cock, T.A.2
Watanabe, M.3
Houten, S.M.4
Champy, M.F.5
Dierich, A.6
Auwerx, J.7
-
29
-
-
0033212964
-
PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota N et al (1999) PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell 4: 597-609
-
(1999)
Mol. Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
-
30
-
-
0035032928
-
Caloric restriction in primates
-
Lane MA, Black A, Handy A, Tilmont EM, Ingram DK, Roth GS (2001) Caloric restriction in primates. Ann NY Acad Sci 928: 287-295
-
(2001)
Ann. NY Acad. Sci.
, vol.928
, pp. 287-295
-
-
Lane, M.A.1
Black, A.2
Handy, A.3
Tilmont, E.M.4
Ingram, D.K.5
Roth, G.S.6
-
31
-
-
0033864582
-
PPARγ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
-
Li AC, Brown KK, Silvestre MJ, Willson TM, Palinski W, Glass CK (2000) PPARγ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice. J Clin Invest 106: 523-531
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 523-531
-
-
Li, A.C.1
Brown, K.K.2
Silvestre, M.J.3
Willson, T.M.4
Palinski, W.5
Glass, C.K.6
-
32
-
-
0031870652
-
Macrophages in human atheroma contain PPARγ: Differentiation-dependent PPARγ expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes in vitro
-
Marx N, Sukhova G, Murphy C, Libby P, Plutzky J (1998) Macrophages in human atheroma contain PPARγ: Differentiation-dependent PPARγ expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes in vitro. Am J Pathol 153: 17-23
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 17-23
-
-
Marx, N.1
Sukhova, G.2
Murphy, C.3
Libby, P.4
Plutzky, J.5
-
33
-
-
0037373008
-
Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
-
Matsusue K, Haluzik M, Lambert G, Yim SH, Gavrilova O, Ward JM, Brewer B, Reitman ML, Gonzalez FJ (2003) Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. J Clin Invest 111: 737-747
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 737-747
-
-
Matsusue, K.1
Haluzik, M.2
Lambert, G.3
Yim, S.H.4
Gavrilova, O.5
Ward, J.M.6
Brewer, B.7
Reitman, M.L.8
Gonzalez, F.J.9
-
34
-
-
0033973843
-
Improved insulin-sensitivity in mice heterozygous for PPARγ deficiency
-
Miles PD, Barak Y, He W, Evans RM, Olefsky JM (2000) Improved insulin-sensitivity in mice heterozygous for PPARγ deficiency. J Clin Invest 105: 287-292
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 287-292
-
-
Miles, P.D.1
Barak, Y.2
He, W.3
Evans, R.M.4
Olefsky, J.M.5
-
35
-
-
0035139016
-
The role of PPARγ in macrophage differentiation and cholesterol uptake
-
Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW (2001) The role of PPARγ in macrophage differentiation and cholesterol uptake. Nat Med 7: 41-47
-
(2001)
Nat. Med.
, vol.7
, pp. 41-47
-
-
Moore, K.J.1
Rosen, E.D.2
Fitzgerald, M.L.3
Randow, F.4
Andersson, L.P.5
Altshuler, D.6
Milstone, D.S.7
Mortensen, R.M.8
Spiegelman, B.M.9
Freeman, M.W.10
-
36
-
-
0033766035
-
A selective PPARγ modulator blocks adipocyte differentiation but stimulates glucose uptake in 3T3-L1 adipocytes
-
Mukherjee R, Hoener PA, Jow L, Bilakovics J, Klausing K, Mais DE, Faulkner A, Croston GE, Paterniti JR (2000) A selective PPARγ modulator blocks adipocyte differentiation but stimulates glucose uptake in 3T3-L1 adipocytes. Mol Endocrinol 14: 1425-1433
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1425-1433
-
-
Mukherjee, R.1
Hoener, P.A.2
Jow, L.3
Bilakovics, J.4
Klausing, K.5
Mais, D.E.6
Faulkner, A.7
Croston, G.E.8
Paterniti, J.R.9
-
37
-
-
0032540325
-
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
-
Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM (1998) Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 93: 229-240
-
(1998)
Cell
, vol.93
, pp. 229-240
-
-
Nagy, L.1
Tontonoz, P.2
Alvarez, J.G.3
Chen, H.4
Evans, R.M.5
-
38
-
-
0037192473
-
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
-
Nemoto S, Finkel T (2002) Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 295: 2450-2452
-
(2002)
Science
, vol.295
, pp. 2450-2452
-
-
Nemoto, S.1
Finkel, T.2
-
39
-
-
16944362008
-
Genomewide search for genes influencing percent body fat in Pima indians: Suggestive linkage at chromosome 11Q21 Q22
-
Norman RA, Thompson DB, Foroud T, Garvey WT, Bennett PH, Bogardus C, Ravussin E (1997) Genomewide search for genes influencing percent body fat in Pima indians: Suggestive linkage at chromosome 11Q21 Q22. Am J Hum Genet 60: 166-173
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 166-173
-
-
Norman, R.A.1
Thompson, D.B.2
Foroud, T.3
Garvey, W.T.4
Bennett, P.H.5
Bogardus, C.6
Ravussin, E.7
-
40
-
-
85047693638
-
Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
-
Norris AW et al (2003) Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. J Clin Invest 112: 608-618
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 608-618
-
-
Norris, A.W.1
-
41
-
-
0036399805
-
PPARγ and glucose homeostasis
-
Picard F, Auwerx J (2002) PPARγ and glucose homeostasis. Annu Rev Nutr 22: 167-197
-
(2002)
Annu. Rev. Nutr.
, vol.22
, pp. 167-197
-
-
Picard, F.1
Auwerx, J.2
-
42
-
-
0141920726
-
Genetic modulation of PPARγ phosphorylation regulates insulin sensitivity
-
Rangwala SM, Rhoades B, Shapiro JS, Rich AS, Kim JK, Shulman GI, Kaestner KH, Lazar MA (2003) Genetic modulation of PPARγ phosphorylation regulates insulin sensitivity. Dev Cell 5: 657-663
-
(2003)
Dev. Cell
, vol.5
, pp. 657-663
-
-
Rangwala, S.M.1
Rhoades, B.2
Shapiro, J.S.3
Rich, A.S.4
Kim, J.K.5
Shulman, G.I.6
Kaestner, K.H.7
Lazar, M.A.8
-
43
-
-
0032484224
-
A potent antidiabetic thiazolidinedione with unique PPARγ-activating properties
-
Reginato MJ, Bailey ST, Krakow SL, Minami C, Ishii S, Tanaka H, Lazar MA (1998) A potent antidiabetic thiazolidinedione with unique PPARγ-activating properties. J Biol Chem 273: 32679-32684
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32679-32684
-
-
Reginato, M.J.1
Bailey, S.T.2
Krakow, S.L.3
Minami, C.4
Ishii, S.5
Tanaka, H.6
Lazar, M.A.7
-
44
-
-
0036007025
-
PPARγ knockdown by engineered transcription factors: Exogenous PPARγ2 but not PPARγ1 reactivates adipogenesis
-
Ren D, Collingwood TN, Rebar EJ, Wolffe AP, Camp HS (2002) PPARγ knockdown by engineered transcription factors: Exogenous PPARγ2 but not PPARγ1 reactivates adipogenesis. Genes Dev 16: 27-32
-
(2002)
Genes Dev.
, vol.16
, pp. 27-32
-
-
Ren, D.1
Collingwood, T.N.2
Rebar, E.J.3
Wolffe, A.P.4
Camp, H.S.5
-
45
-
-
0031886864
-
The PPARγ is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK (1998) The PPARγ is a negative regulator of macrophage activation. Nature 391: 79-82
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
46
-
-
0037625000
-
Alanine for proline substitution in the PPARγ2 (PPARG2) gene and the risk of incident myocardial infarction
-
Ridker PM, Cook NR, Cheng S, Erlich HA, Lindpaintner K, Plutzky J, Zee RY (2003) Alanine for proline substitution in the PPARγ2 (PPARG2) gene and the risk of incident myocardial infarction. Arterioscler Thromb Vasc Biol 23: 859-863
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 859-863
-
-
Ridker, P.M.1
Cook, N.R.2
Cheng, S.3
Erlich, H.A.4
Lindpaintner, K.5
Plutzky, J.6
Zee, R.Y.7
-
47
-
-
0036843143
-
A new selective PPARγ antagonist with antiobesity and antidiabetic activity
-
Rieusset J, Touri F, Michalik L, Escher P, Desvergne B, Niesor E, Wahli W (2002) A new selective PPARγ antagonist with antiobesity and antidiabetic activity. Mol Endocrinol 16: 2628-2644
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 2628-2644
-
-
Rieusset, J.1
Touri, F.2
Michalik, L.3
Escher, P.4
Desvergne, B.5
Niesor, E.6
Wahli, W.7
-
48
-
-
0032189782
-
Obesity associated with a mutation in a genetic regulator of adipocyte differentiation
-
Ristow M, Muller-Wieland D, Pfeiffer A, Krone W, Kahn CR (1998) Obesity associated with a mutation in a genetic regulator of adipocyte differentiation. N Engl J Med 339: 953-959
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 953-959
-
-
Ristow, M.1
Muller-Wieland, D.2
Pfeiffer, A.3
Krone, W.4
Kahn, C.R.5
-
49
-
-
2642557181
-
A unique PPARγ ligand with potent insulin-sensitizing yet weak adipogenic activity
-
Rocchi S et al (2001) A unique PPARγ ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol Cell 8: 737-747
-
(2001)
Mol. Cell
, vol.8
, pp. 737-747
-
-
Rocchi, S.1
-
50
-
-
0141450254
-
Targeted elimination of PPARγ in β-cells leads to abnormalities in islet mass without compromising glucose homeostasis
-
Rosen ED et al (2003) Targeted elimination of PPARγ in β-cells leads to abnormalities in islet mass without compromising glucose homeostasis. Mol Cell Biol 23: 7222-7229
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 7222-7229
-
-
Rosen, E.D.1
-
51
-
-
0033213631
-
PPARγ is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM (1999) PPARγ is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell 4: 611-617
-
(1999)
Mol. Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
Spiegelman, B.M.7
Mortensen, R.M.8
-
52
-
-
0035851187
-
PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen ED, Spiegelman BM (2001) PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 276: 37731-37734
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
53
-
-
1642420745
-
Dietary fat and postprandial lipids
-
Sanders TA (2003) Dietary fat and postprandial lipids. Curr Atheroscler Rep 5: 445-451
-
(2003)
Curr. Atheroscler. Rep.
, vol.5
, pp. 445-451
-
-
Sanders, T.A.1
-
54
-
-
0344375097
-
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-γ
-
Savage DB et al (2003) Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-γ. Diabetes 52: 910-917
-
(2003)
Diabetes
, vol.52
, pp. 910-917
-
-
Savage, D.B.1
-
55
-
-
0347772237
-
Beneficial effect of troglitazone, an insulin-sensitizing antidiabetic agent, on coronary circulation in patients with non-insulin-dependent diabetes mellitus
-
Sekiya M, Suzuki J, Watanabe K, Funada J, Otani T, Akutsu H (2001) Beneficial effect of troglitazone, an insulin-sensitizing antidiabetic agent, on coronary circulation in patients with non-insulin-dependent diabetes mellitus. Jpn Circ J 65: 487-490
-
(2001)
Jpn. Circ. J.
, vol.65
, pp. 487-490
-
-
Sekiya, M.1
Suzuki, J.2
Watanabe, K.3
Funada, J.4
Otani, T.5
Akutsu, H.6
-
56
-
-
0026070429
-
Body weight and longevity in genetically obese and non-obese mice fed fat-modified diets
-
Smith BA, Edwards MS, Ballachey BE, Cramer DA, Sutherland TM (1991) Body weight and longevity in genetically obese and non-obese mice fed fat-modified diets. Growth Dev Aging 55: 81-89
-
(1991)
Growth Dev. Aging
, vol.55
, pp. 81-89
-
-
Smith, B.A.1
Edwards, M.S.2
Ballachey, B.E.3
Cramer, D.A.4
Sutherland, T.M.5
-
57
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273: 59-63
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
58
-
-
0034332862
-
Troglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with non-insulin dependent diabetes mellitus: A serial intravascular ultrasound study
-
Takagi T, Akasaka T, Yamamuro A, Honda Y, Hozumi T, Morioka S, Yoshida K (2000) Troglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with non-insulin dependent diabetes mellitus: A serial intravascular ultrasound study. J Am Coll Cardiol 36: 1529-1535
-
(2000)
J. Am. Coll. Cardiol.
, vol.36
, pp. 1529-1535
-
-
Takagi, T.1
Akasaka, T.2
Yamamuro, A.3
Honda, Y.4
Hozumi, T.5
Morioka, S.6
Yoshida, K.7
-
59
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar M, Bartke A, Antebi A (2003) The endocrine regulation of aging by insulin-like signals. Science 299: 1346-1351
-
(2003)
Science
, vol.299
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
60
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz P, Hu E, Spiegelman BM (1994) Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 79: 1147-1156
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
61
-
-
0032540012
-
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM (1998) PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93: 241-252
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.3
Thomazy, V.A.4
Evans, R.M.5
-
62
-
-
0037134040
-
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
-
Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ, DiStefano PS, Chiang LW, Greenberg ME (2002) DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296: 530-534
-
(2002)
Science
, vol.296
, pp. 530-534
-
-
Tran, H.1
Brunet, A.2
Grenier, J.M.3
Datta, S.R.4
Fornace, A.J.5
DiStefano, P.S.6
Chiang, L.W.7
Greenberg, M.E.8
-
64
-
-
85047685428
-
Inhibition of RXR and PPARγ ameliorates diet-induced obesity and type 2 diabetes
-
Yamauchi T et al (2001) Inhibition of RXR and PPARγ ameliorates diet-induced obesity and type 2 diabetes. J Clin Invest 108: 1001-1013
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1001-1013
-
-
Yamauchi, T.1
|