The biochemical basis for the anti-inflammatory and cytoprotective actions of ethyl pyruvate and related compounds

Biochemical Pharmacology

Volumn 80, Issue 2, 2010, Pages 151-159

  Kao, Kenneth K ^a,b   Fink, Mitchell P ^a,b  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Glyoxalase; Inflammation; Janus associated kinase; NF kappaB; ROS

Indexed keywords

2 ACETAMIDOACRYLATE; 2 ACETAMIDOACRYLIC ACID METHYL EXTER; 2 OXOGLUTARIC ACID; DIPYRUVYL ACETYL GLYCEROL; ETHYLPYRUVIC ACID; METHYLPYRUVIC ACID; OXALOACETIC ACID; OXOACID; PYRUVIC ACID; PYRUVIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; BRAIN ISCHEMIA; CATARACT; CELL PROTECTION; COLITIS; CYTOKINE RELEASE; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEMORRHAGIC SHOCK; HUMAN; IMMUNOMODULATION; INFLAMMATION; LIVER INJURY; LIVER TUMOR; LUNG FIBROSIS; NEUROPROTECTION; NONHUMAN; NOTE; PANCREATITIS; PRIORITY JOURNAL; SCALD; SEPSIS; SIGNAL TRANSDUCTION; SPINAL CORD ISCHEMIA;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYTOPROTECTION; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; HUMANS; OXIDATIVE STRESS; PYRUVATES; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 77952671610     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.03.007     Document Type: Note

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