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Volumn 142, Issue 2, 2007, Pages 166-171

Beneficial effects of ethyl pyruvate in septic shock from peritonitis

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; PYRUVIC ACID ETHYL ESTER; RINGER LACTATE SOLUTION; UNCLASSIFIED DRUG;

EID: 33847165372     PISSN: 00040010     EISSN: 15383644     Source Type: Journal    
DOI: 10.1001/archsurg.142.2.166     Document Type: Article
Times cited : (25)

References (38)
  • 1
    • 31344461826 scopus 로고    scopus 로고
    • Sepsis in European intensive care units: Results of the SOAP study
    • Vincent JL, Sakr Y, Sprung CL, et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med. 2006;34:344-353.
    • (2006) Crit Care Med , vol.34 , pp. 344-353
    • Vincent, J.L.1    Sakr, Y.2    Sprung, C.L.3
  • 2
    • 0038001565 scopus 로고    scopus 로고
    • Ringer's ethyl pyruvate solution: A novel resuscitation fluid for the treatment of hemorrhagic shock and sepsis
    • Fink MP. Ringer's ethyl pyruvate solution: a novel resuscitation fluid for the treatment of hemorrhagic shock and sepsis. J Trauma. 2003;54:S141-S143.
    • (2003) J Trauma , vol.54
    • Fink, M.P.1
  • 3
    • 0037616308 scopus 로고    scopus 로고
    • Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock
    • Venkataraman R, Kellum JA, Song M, Fink MP. Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock. Shock. 2002;18:507-512.
    • (2002) Shock , vol.18 , pp. 507-512
    • Venkataraman, R.1    Kellum, J.A.2    Song, M.3    Fink, M.P.4
  • 4
    • 0142249406 scopus 로고    scopus 로고
    • Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice
    • Miyaji T, Hu X, Yuen PS, et al. Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice. Kidney Int. 2003;64:1620-1631.
    • (2003) Kidney Int , vol.64 , pp. 1620-1631
    • Miyaji, T.1    Hu, X.2    Yuen, P.S.3
  • 5
    • 0037125985 scopus 로고    scopus 로고
    • Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation
    • Ulloa L, Ochani M, Yang H, et al. Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proc Natl Acad Sci U S A. 2002;99:12 351-12 356.
    • (2002) Proc Natl Acad Sci U S A , vol.99
    • Ulloa, L.1    Ochani, M.2    Yang, H.3
  • 6
    • 0042829191 scopus 로고    scopus 로고
    • Low-dose vasopressin in the treatment of septic shock in sheep
    • Sun Q, Dimopoulos G, Nguyen DN, et al. Low-dose vasopressin in the treatment of septic shock in sheep. Am J Respir Crit Care Med. 2003;168:481-486.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 481-486
    • Sun, Q.1    Dimopoulos, G.2    Nguyen, D.N.3
  • 7
    • 9644297875 scopus 로고    scopus 로고
    • Use of low tidal volume in septic shock may decrease severity of subsequent acute lung injury
    • Su F, Nguyen ND, Creteur J, et al. Use of low tidal volume in septic shock may decrease severity of subsequent acute lung injury. Shock. 2004;22:145-150.
    • (2004) Shock , vol.22 , pp. 145-150
    • Su, F.1    Nguyen, N.D.2    Creteur, J.3
  • 8
    • 0344309146 scopus 로고    scopus 로고
    • Dose-dependent effects of ethyl pyruvate in mice subjected to mesenteric ischemia and reperfusion
    • Uchiyama T, Delude RL, Fink MP. Dose-dependent effects of ethyl pyruvate in mice subjected to mesenteric ischemia and reperfusion. Intensive Care Med. 2003;29:2050-2058.
    • (2003) Intensive Care Med , vol.29 , pp. 2050-2058
    • Uchiyama, T.1    Delude, R.L.2    Fink, M.P.3
  • 9
    • 0036088799 scopus 로고    scopus 로고
    • Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock
    • Yang R, Gallo DJ, Baust JJ, et al. Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol. 2002;283:G212-G221.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Yang, R.1    Gallo, D.J.2    Baust, J.J.3
  • 10
    • 0036599639 scopus 로고    scopus 로고
    • Resuscitation from hemorrhagic shock with Ringer's ethyl pyruvate solution improves survival and ameliorates intestinal mucosal hyperpermeability in rats
    • Tawadrous ZS, Delude RL, Fink MP. Resuscitation from hemorrhagic shock with Ringer's ethyl pyruvate solution improves survival and ameliorates intestinal mucosal hyperpermeability in rats. Shock. 2002;17:473-477.
    • (2002) Shock , vol.17 , pp. 473-477
    • Tawadrous, Z.S.1    Delude, R.L.2    Fink, M.P.3
  • 11
    • 0037213248 scopus 로고    scopus 로고
    • Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers
    • Sappington PL, Han X, Yang R, Delude RL, Fink MP. Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers. J Pharmacol Exp Ther. 2003;304:464-476.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 464-476
    • Sappington, P.L.1    Han, X.2    Yang, R.3    Delude, R.L.4    Fink, M.P.5
  • 12
    • 7944233880 scopus 로고    scopus 로고
    • Ethyl pyruvate reduces liver injury in a murine model of extrahepatic cholestasis
    • Yang R, Uchiyama T, Watkins SK, Han X, Fink MP. Ethyl pyruvate reduces liver injury in a murine model of extrahepatic cholestasis. Shock. 2004;22:369-375.
    • (2004) Shock , vol.22 , pp. 369-375
    • Yang, R.1    Uchiyama, T.2    Watkins, S.K.3    Han, X.4    Fink, M.P.5
  • 13
    • 24944460440 scopus 로고    scopus 로고
    • Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia
    • Hauser B, Kick J, Asfar P, et al. Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia. Crit Care Med. 2005;33:2034-2042.
    • (2005) Crit Care Med , vol.33 , pp. 2034-2042
    • Hauser, B.1    Kick, J.2    Asfar, P.3
  • 14
    • 0002015656 scopus 로고
    • The estimation of the surface area of the body
    • Dubois EF, ed, Philadelphia, Pa: Lea & Febiger;
    • Dubois EF. The estimation of the surface area of the body. In: Dubois EF, ed. Basal Metabolism in Health and Disease. Philadelphia, Pa: Lea & Febiger; 1936:125-144.
    • (1936) Basal Metabolism in Health and Disease , pp. 125-144
    • Dubois, E.F.1
  • 15
    • 0030294357 scopus 로고    scopus 로고
    • Hyperoxia activates NF-kappaB and increases TNF-alpha and IFN-gamma gene expression in mouse pulmonary lymphocytes
    • Shea LM, Beehler C, Schwartz M, Shenkar R, Tuder R, Abraham E. Hyperoxia activates NF-kappaB and increases TNF-alpha and IFN-gamma gene expression in mouse pulmonary lymphocytes. J Immunol. 1996;157:3902-3908.
    • (1996) J Immunol , vol.157 , pp. 3902-3908
    • Shea, L.M.1    Beehler, C.2    Schwartz, M.3    Shenkar, R.4    Tuder, R.5    Abraham, E.6
  • 16
    • 0035217837 scopus 로고    scopus 로고
    • The antioxidant potential of pyruvate in the amitochondriate diplomonads Giardia intestinalis and Hexamita inflata
    • Biagini GA, Park JH, Lloyd D, Edwards MR. The antioxidant potential of pyruvate in the amitochondriate diplomonads Giardia intestinalis and Hexamita inflata. Microbiology. 2001;147:3359-3365.
    • (2001) Microbiology , vol.147 , pp. 3359-3365
    • Biagini, G.A.1    Park, J.H.2    Lloyd, D.3    Edwards, M.R.4
  • 17
    • 51149212381 scopus 로고
    • Oxidation of α-diketons and α-keto-acids by hydrogen peroxide
    • Bunton CA. Oxidation of α-diketons and α-keto-acids by hydrogen peroxide. Nature. 1949;163:444-446.
    • (1949) Nature , vol.163 , pp. 444-446
    • Bunton, C.A.1
  • 19
    • 0032738998 scopus 로고    scopus 로고
    • Antioxidative properties of pyruvate and protection of the ischemic rat heart during cardioplegia
    • Dobsak P, Courderot-Masuyer C, Zeller M, et al. Antioxidative properties of pyruvate and protection of the ischemic rat heart during cardioplegia. J Cardiovasc Pharmacol. 1999;34:651-659.
    • (1999) J Cardiovasc Pharmacol , vol.34 , pp. 651-659
    • Dobsak, P.1    Courderot-Masuyer, C.2    Zeller, M.3
  • 20
    • 84961006890 scopus 로고    scopus 로고
    • Montgomery CM, Webb JL. Metabolic studies on heart mitochondria, II: the inhibitory action of parapyruvate on the tricarboxylic acid cycle. J Biol Chem. 1956;221:359-368.
    • Montgomery CM, Webb JL. Metabolic studies on heart mitochondria, II: the inhibitory action of parapyruvate on the tricarboxylic acid cycle. J Biol Chem. 1956;221:359-368.
  • 21
    • 0024600885 scopus 로고
    • Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart: Near-complete prevention of reperfusion contractile failure
    • Bunger R, Mallet RT, Hartman DA. Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart: near-complete prevention of reperfusion contractile failure. Eur J Biochem. 1989;180:221-233.
    • (1989) Eur J Biochem , vol.180 , pp. 221-233
    • Bunger, R.1    Mallet, R.T.2    Hartman, D.A.3
  • 22
    • 0030030820 scopus 로고    scopus 로고
    • Pyruvate prevents ischemia-reperfusion mucosal injury of rat small intestine
    • Cicalese L, Lee K, Schraut W, Watkins S, Borle A, Stanko R. Pyruvate prevents ischemia-reperfusion mucosal injury of rat small intestine. Am J Surg. 1996;171:97-100.
    • (1996) Am J Surg , vol.171 , pp. 97-100
    • Cicalese, L.1    Lee, K.2    Schraut, W.3    Watkins, S.4    Borle, A.5    Stanko, R.6
  • 23
    • 0035888871 scopus 로고    scopus 로고
    • Protection by pyruvate against transient forebrain ischemia in rats
    • Lee JY, Kim YH, Koh JY. Protection by pyruvate against transient forebrain ischemia in rats. J Neurosci. 2001;21:1-6.
    • (2001) J Neurosci , vol.21 , pp. 1-6
    • Lee, J.Y.1    Kim, Y.H.2    Koh, J.Y.3
  • 24
    • 0034910965 scopus 로고    scopus 로고
    • Sodium pyruvate is better than sodium chloride as a resuscitation solution in a rodent model of profound hemorrhagic shock
    • Slovin PN, Huang CJ, Cade JR, et al. Sodium pyruvate is better than sodium chloride as a resuscitation solution in a rodent model of profound hemorrhagic shock. Resuscitation. 2001;50:109-115.
    • (2001) Resuscitation , vol.50 , pp. 109-115
    • Slovin, P.N.1    Huang, C.J.2    Cade, J.R.3
  • 26
    • 3142759947 scopus 로고    scopus 로고
    • Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis
    • Yang R, Uchiyama T, Alber SM, et al. Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis. Crit Care Med. 2004;32:1453-1459.
    • (2004) Crit Care Med , vol.32 , pp. 1453-1459
    • Yang, R.1    Uchiyama, T.2    Alber, S.M.3
  • 27
    • 0347758406 scopus 로고    scopus 로고
    • Evidence that glutathione depletion is a mechanism responsible for the anti-inflammatory effects of ethyl pyruvate in cultured lipopolysaccharide-stimulated RAW 264.7 cells
    • Song M, Kellum JA, Kaldas H, Fink MP. Evidence that glutathione depletion is a mechanism responsible for the anti-inflammatory effects of ethyl pyruvate in cultured lipopolysaccharide-stimulated RAW 264.7 cells. J Pharmacol Exp Ther. 2004;308:307-316.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 307-316
    • Song, M.1    Kellum, J.A.2    Kaldas, H.3    Fink, M.P.4
  • 28
    • 14344255881 scopus 로고    scopus 로고
    • Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65
    • Han Y, Englert JA, Yang R, Delude RL, Fink MP. Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65. J Pharmacol Exp Ther. 2005;312:1097-1105.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 1097-1105
    • Han, Y.1    Englert, J.A.2    Yang, R.3    Delude, R.L.4    Fink, M.P.5
  • 30
    • 2342432453 scopus 로고    scopus 로고
    • Ethyl pyruvate preserves cardiac function and attenuates oxidative injury after prolonged myocardial ischemia
    • Woo YJ, Taylor MD, Cohen JE, et al. Ethyl pyruvate preserves cardiac function and attenuates oxidative injury after prolonged myocardial ischemia. J Thorac Cardiovasc Surg. 2004;127:1262-1269.
    • (2004) J Thorac Cardiovasc Surg , vol.127 , pp. 1262-1269
    • Woo, Y.J.1    Taylor, M.D.2    Cohen, J.E.3
  • 31
    • 4544347659 scopus 로고    scopus 로고
    • Pyruvate prevents cardiac dysfunction and AMP-activated protein kinase activation by hydrogen peroxide in isolated rat hearts
    • Leon H, Atkinson LL, Sawicka J, Strynadka K, Lopaschuk GD, Schulz R. Pyruvate prevents cardiac dysfunction and AMP-activated protein kinase activation by hydrogen peroxide in isolated rat hearts. Can J Physiol Pharmacol. 2004;82:409-416.
    • (2004) Can J Physiol Pharmacol , vol.82 , pp. 409-416
    • Leon, H.1    Atkinson, L.L.2    Sawicka, J.3    Strynadka, K.4    Lopaschuk, G.D.5    Schulz, R.6
  • 32
    • 0942276499 scopus 로고    scopus 로고
    • The intermediary metabolite pyruvate attenuates stunning and reduces infarct size in in vivo porcine myocardium
    • Kristo G, Yoshimura Y, Niu J, et al. The intermediary metabolite pyruvate attenuates stunning and reduces infarct size in in vivo porcine myocardium. Am J Physiol Heart Circ Physiol. 2004;286:H517-H524.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Kristo, G.1    Yoshimura, Y.2    Niu, J.3
  • 33
    • 1342345252 scopus 로고    scopus 로고
    • Improved systolic and diastolic myocardial function with intracoronary pyruvate in patients with congestive heart failure
    • Hermann HP, Arp J, Pieske B, et al. Improved systolic and diastolic myocardial function with intracoronary pyruvate in patients with congestive heart failure. Eur J Heart Fail. 2004;6:213-218.
    • (2004) Eur J Heart Fail , vol.6 , pp. 213-218
    • Hermann, H.P.1    Arp, J.2    Pieske, B.3
  • 35
    • 0034042444 scopus 로고    scopus 로고
    • Pyruvate: Metabolic protector of cardiac performance
    • Mallet RT. Pyruvate: metabolic protector of cardiac performance. Proc Soc Exp Biol Med. 2000;223:136-148.
    • (2000) Proc Soc Exp Biol Med , vol.223 , pp. 136-148
    • Mallet, R.T.1
  • 36
    • 0026354819 scopus 로고
    • Colloid oncotic pressure and body water dynamics in septic and injured patients
    • Lucas CE, Ledgerwood AM, Rachwal WJ, Grabow D, Saxe JM. Colloid oncotic pressure and body water dynamics in septic and injured patients. J Trauma. 1991;31:927-931.
    • (1991) J Trauma , vol.31 , pp. 927-931
    • Lucas, C.E.1    Ledgerwood, A.M.2    Rachwal, W.J.3    Grabow, D.4    Saxe, J.M.5
  • 37
    • 0034883436 scopus 로고    scopus 로고
    • Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats
    • Sims CA, Wattanasirichaigoon S, Menconi MJ, Ajami AM, Fink MP. Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats. Crit Care Med. 2001;29:1513-1518.
    • (2001) Crit Care Med , vol.29 , pp. 1513-1518
    • Sims, C.A.1    Wattanasirichaigoon, S.2    Menconi, M.J.3    Ajami, A.M.4    Fink, M.P.5
  • 38
    • 17144422899 scopus 로고    scopus 로고
    • Future strategies in the treatment of acute renal failure: Growth factors, stem cells, and other novel therapies
    • Bates CM, Lin F. Future strategies in the treatment of acute renal failure: growth factors, stem cells, and other novel therapies. Curr Opin Pediatr. 2005;17:215-220.
    • (2005) Curr Opin Pediatr , vol.17 , pp. 215-220
    • Bates, C.M.1    Lin, F.2


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