Inhibition by ethyl pyruvate of the nuclear translocation of nuclear factor-κB in cultured lung epithelial cells

Pulmonary Pharmacology and Therapeutics

Volumn 23, Issue 4, 2010, Pages 308-315

  Mizutani, Ayako ^a   Maeda, Noriko ^a   Toku, Seikichi ^a   Isohama, Yoichiro ^b   Sugahara, Kazuhiro ^a   Yamamoto, Hideyuki ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

A549 cells; Alveolar epithelial cells; Ethyl pyruvate; Inflammation; Nuclear factor B; Tumor necrosis factor

Indexed keywords

ANTIINFLAMMATORY AGENT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PYRUVIC ACID ETHYL ESTER; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; REPORTER GENE; TRANSCRIPTION INITIATION;

CELL LINE; CELL NUCLEUS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GENES, REPORTER; HUMANS; I-KAPPA B PROTEINS; IMMUNOBLOTTING; NF-KAPPA B; PHOSPHORYLATION; PROTEIN TRANSPORT; PULMONARY ALVEOLI; PYRUVATES; TIME FACTORS; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77952668967     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2010.03.002     Document Type: Article

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