Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers

Journal of Pharmacology and Experimental Therapeutics

Volumn 304, Issue 1, 2003, Pages 464-476

  Sappington, Penny L ^a   Han, Xiaonan ^a   Yang, Runkuan ^a   Delude, Russell L ^a   Fink, Mitchell P ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; ETHYLPYRUVATE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OCCLUDIN; PROTEIN ZO1; PYRUVATE SODIUM; PYRUVIC ACID DERIVATIVE; RINGER LACTATE SOLUTION; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL TRANSLOCATION; CELL STRAIN CACO 2; CONTROLLED STUDY; ENDOTOXEMIA; HEMORRHAGIC SHOCK; IMMUNOSTIMULATION; INTESTINE CELL; INTESTINE EPITHELIUM; INTESTINE MUCOSA PERMEABILITY; MALE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESUSCITATION;

ADJUVANTS, IMMUNOLOGIC; ALANINE TRANSAMINASE; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BLOTTING, WESTERN; CACO-2 CELLS; CELL NUCLEUS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS; ENDOTOXEMIA; HEPATITIS, TOXIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; LIVER; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PYRUVATES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIGHT JUNCTIONS;

EID: 0037213248     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.043182     Document Type: Article

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