Ethyl pyruvate protects PC12 cells from dopamine-induced apoptosis

European Journal of Pharmacology

Volumn 508, Issue 1-3, 2005, Pages 57-68

  Wang, Li Zhen ^a   Sun, Wan Chun ^a   Zhu, Xing Zu ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Dopamine; Ethyl pyruvate; Nuclear transcription factor kappa B; Oxidative stress; p53; Parkinson's disease

Indexed keywords

DOPAMINE; ETHYLPYRUVATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P53; PYRUVIC ACID DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ACETYLCYSTEINE; ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL SURVIVAL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN PEROXIDE; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; NF-KAPPA B; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRUVATES; RATS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 12844269491     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.12.020     Document Type: Article

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