Lens thiol depletion by peroxynitrite. Protective effect of pyruvate

Molecular and Cellular Biochemistry

Volumn 298, Issue 1-2, 2007, Pages 199-204

  Varma, Shambhu D ^a   Hegde, Kavita R ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Lens and cataract; Nitrosative stress; Peroxynitrite induced pyruvate decarboxylation; Thiol protection

Indexed keywords

CARBON DIOXIDE; GLUTATHIONE; LINSIDOMINE; NITRIC OXIDE; PEROXYNITRITE; PYRUVIC ACID; THIOL;

ANIMAL TISSUE; ARTICLE; CHEMICAL BOND; CONTROLLED STUDY; DECARBOXYLATION; EYE PROTECTION; LENS; LENS DISEASE; NITROSATIVE STRESS; NONHUMAN; OXIDATION; PROTEIN DEPLETION; RAT;

ANIMALS; DECARBOXYLATION; GLUTATHIONE; LENS, CRYSTALLINE; MOLSIDOMINE; NITRIC OXIDE DONORS; PEROXYNITROUS ACID; PYRUVATES; RATS; SULFHYDRYL COMPOUNDS;

EID: 34247204860     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-9352-y     Document Type: Article

References (22)

1. Varma SD, Morris SM (1988) Peroxide damage to the eye lens in vitro: prevention by pyruvate. Free Rad Res Comm 4:283-290
2. Varma SD, Hegde K, Henein M (2003) Oxidative damage to mouse lens in culture. Protective effect of pyruvate. Biochim Biphys Acta 1621:246-252
3. Varma SD, Ramachandran S, Devamanoharan PS, Morris SM, Ali AH (1995) Prevention of oxidative damage to rat lens in vitro by pyruvate: possible attenuation in vivo. Curr Eye Res 14:643-649
4. Hegde KR, Varma SD (2005) Prevention of cataract by pyruvate in experimentally diabetic mice. Mol Cell Biochem 269:115-20
5. Holleman MAF (1904) Note on the action of oxygenated water on alpha-keto acids and 1,2, dicetones. Recl Tran Chi Pays-bas Belq 23:169-172
6. Fenton HJH, Jones HO (1900) The oxidation of organic acids in presence of ferrous iron, Part I. J Chem Soc Trans 77:69-76
7. Crestanello JA, Lingle DM, Millili J, Whitman GJ (1998) Pyruvate improves myocardial tolerance to reperfusion injury by acting as an antioxidant: A chemiluminescence study. Surgery 124:92-99
8. Desagher S, Glowinski J, Premont J (1997) Pyruvate protects neurons against hydrogen peroxide-induced toxicity. J Neurosci 17:9060-9067
9. Wang XF, Cynader MS (2001) Pyruvate released by astrocytes protects neurons from copper-catalyzed cysteine neurotoxicity. J Neurosci 21:3322-3331
10. Haber F, Weiss J (1934) The catalytic decomposition of hydrogen peroxide by iron salts. Proc Royal Soc Lond Series A 147:332-351
11. Ervens B, Gligorovski S, Herrmann H (2003) Temperature dependent rate constants for hydroxyl radical reactions with organic compounds in aqueous solutions. Phys Chem Chem Phys 5:1811-1824
12. Millouki A, Mu YJ (2003) On atmospheric degradation of pyruvic acid in the gas phase. J Photochem Photobiol A Chem 157:295-300
13. Stadler K, Jenei V, von Bolcshazy G, Somogyi A, Jakus J (2003) Increased nitric oxide levels as an early sign of premature aging in diabetes. Free Radic Biol Med 35:1240-1251
14. Kreines K, Rowe KW (1979) Cataracts and adult diabetes. Ohio State Med J 75:785-786
15. Devamanoharan PS, Henein M, Morris S, Ramachandran S, Richards RD, Varma SD (1991) Prevention of selenite cataract by vitamin C. Exp Eye Res 52:563-568
16. Trevithick JR, Mitton KP (2000) Vitamins C and E in cataract risk reduction. Int Ophthalmol Clin 40:59-69
17. Taylor A, Jacques PF, Chylack LT Jr, Hankinson SE, Khu PM, Rogers G, Friend J, Tung W, Wolfe JK, Padhye N, Willett WC (2002) Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities. Am J Clin Nutr 75:540-549
18. Trujillo M, Folkes L, Bartesaghi S, Kalyanaraman B, Wardman P,Radi R (2005) Peroxynitrite-derived carbonate and nitrogen dioxide radicals readily react with lipoic and dihydrolipoic acid. Free Rad Biol Med 39:279-288
19. Varma SD, Bauer SA, Richards RD (1987) Hexose Monophosphate Shunt in rat lens: Stimulation by vitamin C. Invest Ophthalmol Vis Sci 28:1164-1169
20. Ellman GL (1959) Tissue sulphydryl groups. Arch Biochem Biophys 82:70-77
21. Varma SD, Kinoshita JH (1974) Sorbitol pathway in diabetic and galactosemic rat lens. Biochim Biophys Acta 338:632-640
22. Ozaki Y, Mizuno A, Itoh K, Iriyama K (1987) Inter and intramolecular disulfide bond formation and related structural changes in the lens proteins. A Raman spectroscopic study in vivo of lens aging. J Biol Chem 262:15545-15551